基于KDIGO 2012指南的肾小球滤过率和尿白蛋白与肌酐比值在泰国社区医院的应用:慢性肾病的患病率及其危险因素

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-12-08 DOI:10.12659/MSMBR.938176

Veeravan Lekskulchai

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引用次数: 0

摘要

肾脏疾病在早期很难被发现;因此，制定了肾脏疾病:改善全球预后(KDIGO) 2012指南，以改善肾脏疾病患者的护理和预后。本研究旨在确定在社区医院服务中应用该指南的临床结果。材料和方法从患者的医疗记录中提取数据，并分析使用估计的肾小球滤过率(eGFR)和尿白蛋白-肌酐比(UACR)检测肾脏疾病的结果。结果36 172例年龄≥18岁的患者使用eGFR检测，76.86%的患者肾功能正常。慢性肾脏疾病(CKD)患病率为8.20%;大多数CKD患者(68%)处于3a和3b期。慢性肾病最常见的病因是糖尿病和高血压。UACR主要用于糖尿病患者。单独UACR≥3mg /mmol肌酐的患者比例明显高于合并eGFR的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Use of Estimated Glomerular Filtration Rate and Urine Albumin-to-Creatinine Ratio Based on KDIGO 2012 Guideline in a Thai Community Hospital: Prevalence of Chronic Kidney Disease and its Risk Factors.

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BACKGROUND Kidney disease is hard to detect at its early stage; therefore, the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guideline was developed for improving care and outcomes of patients with kidney disease. This study aimed to determine clinical outcomes from applying this guideline in a community hospital service. MATERIAL AND METHODS The patients' data were extracted from their medical records and analyzed for outcomes of using the estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) for detecting kidney disease. RESULTS The eGFR was utilized in 36 172 patients aged ≥18 years, and 76.86% of them had normal kidney function. The prevalence of chronic kidney disease (CKD) was 8.20%; most patients (68%) with CKD were in stages 3a and 3b. The most common causes of CKD were diabetes and hypertension. The UACR was mainly used in patients with diabetes. The percentage of patients with UACR ≥3 mg/mmol creatinine alone was significantly higher than that of patients with eGFR.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.