{"title":"Discrete iterative algorithms for scatter-to-attenuation reconstruction in PET","authors":"Yannick Berker, V. Schulz, J. Karp","doi":"10.1109/NSSMIC.2016.8069455","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069455","url":null,"abstract":"Recently, several groups have proposed the use of scattered coincidences in positron emission tomography (PET), aiming at improved attenuation correction using the PET emission data, e.g., in PET-MRI. In this work, we analyzed the behavior of several algorithms, including reconstruction by two-branch scatter-to-attenuation back-projection (BP) and maximum likelihood expectation maximization with a one-step-late update of the system matrix (MLEM-OSL). A maximum-likelihood gradient-ascent (MLGA) approach, as previously proposed by us, was tested with four step sizes and several stabilization and acceleration techniques (Armijo step size rule, conjugate gradients, Nesterov acceleration, and subsets). The convergence speed of all algorithms was compared using phantom simulations in fields of view (FOVs) ranging from rat-sized to human-sized. For MLEM-OSL, based on a numerical criterion distinguishing low- and high-attenuation surfaces of response (SOR), the most useful (low-attenuation) SORs were isolated in order to improve convergence speed. We found that the Armijo step size rule improved convergence speed and enabled the use of conjugate gradients, further improving convergence rates. Alternatively, the use of data subsets yielded near-ideal speed-up of MLGA. Even with identical geometries (up to a spatial scale factor), performance of all algorithms depends on the FOV size, suggesting a new kind of scale problem. In particular, shortcomings of MLEM-OSL prevent convergence to the true solution in large FOVs, where MLGA behaves more favorably. Convergence rates of MLEM-OSL were improved by removing high-attenuation SORs, indicating that, opposing intuition, MLEM-OSL convergence can be improved by using less data.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124339476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pitfalls in MLAA and MLACF","authors":"K. Salvo, M. Defrise","doi":"10.1109/NSSMIC.2016.8069555","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069555","url":null,"abstract":"In time-of-flight (TOF) positron emission tomography (PET) imaging, it is possible to correct for attenuation using only the TOF-PET data. Currently two main iterative algorithms exist for this purpose: MLAA [1] and MLACF [2]. In addition to reconstructing the activity image A, MLAA reconstructs the attenuation map μ, whereas MLACF reconstructs the attenuation correction factors a. While implementing MLAA and MLACF, one has to be careful. Possible pitfalls are: (i) obtaining slice dependent scale factors, (ii) converging to local maxima, (iii) obtaining unbounded estimates, (iv) dividing by zero, and (v) using an incorrect or inefficient update scheme. First we will summarize and expand some previous results of MLAA & MLACF convergence and uniqueness issues. Next we will use this knowledge to understand the pitfalls, while giving details on the implementation to avoid them.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124042826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Januschek, Ivana Klačkov, N. Andresen, P. Denes, S. Hauf, J. Joseph, M. Kuster, C. Tindall
{"title":"Performance of the LBNL FastCCD for the European XFEL","authors":"F. Januschek, Ivana Klačkov, N. Andresen, P. Denes, S. Hauf, J. Joseph, M. Kuster, C. Tindall","doi":"10.1109/NSSMIC.2016.8069829","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069829","url":null,"abstract":"The European X-ray Free Electron Laser (XFEL.EU) is currently being commissioned in Schenefeld, Germany. From 2017 onwards it will provide spatially coherent X-rays of energies between 0.25 keV and 25keV with a unique timing structure. One of the detectors foreseen at XFEL.EU for the soft X-ray regime (energies below 6keV) is a quasi column-parallel readout FastCCD developed by Lawrence Berkeley National Lab (LBNL) specifically for the XFEL.EU requirements. Its sensor has 1920×960 pixels of 30μm ×30μm size with a beam hole in the middle of the sensor. The camera can be operated in full frame and frame store mode. With the FastCCD a frame rate of up to 120 fps can be achieved, but at XFEL.EU the camera settings are optimized for the 10Hz XFEL bunch-mode. The detector has been delivered to XFEL.EU. Results of the performance tests and calibration done using the XFEL.EU detector calibration infrastructure are presented quantifying noise level, gain and energy resolution.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124141174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A combination of multiple channels of FPGA based time-to-digital converter for high time precision","authors":"Qiang Cao, Yonggang Wang, Chong Liu","doi":"10.1109/NSSMIC.2016.8069649","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069649","url":null,"abstract":"The full hardware solution introduced in our previous work could implement multi-channel time-to-digital converters (TDCs) in a Xilinx Kintex-7 FPGA with better than 10 ps RMS precision and 710 MHz measurement throughput. Based on these fundamental TDC blocks, we propose a method to improve the time precision further by merging multiple TDC blocks, which is equivalent to increasing the number of TDC bins multiple times. Two merged TDC channels, each with four TDC blocks, are implemented in the Kintex-7 FPGA and the performance is evaluated. For fixed time intervals in the range from 0 to 20 ns, the average RMS precision measured by the two TDC channels reaches 3.1 ps. The test results show that the FPGA based multi-channel TDC system can be flexibly configured as either more TDC channels with a low time precision or fewer TDC channels with a high time precision.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127673106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James T. Johnson, S. Thompson, S. Watson, D. Chichester
{"title":"Optimization of a fast neutron scintillator for real-time pulse shape discrimination in the transient reactor test facility (TREAT) hodoscope","authors":"James T. Johnson, S. Thompson, S. Watson, D. Chichester","doi":"10.1109/NSSMIC.2016.8069782","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069782","url":null,"abstract":"We present a multi-channel, fast-neutron/photon detection system that uses ZnS(Ag) scintillator detectors. The system employs field-programmable gate arrays to pulse-shape analysis for real-time all-digital neutron/photon differentiation, producing particle-dependent pulse height and temporal distributions while allowing count rates in excess of 1,000,000 events per second per channel. The system size is scalable in blocks of 16 channels.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126317459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Bedeschi, R. Cenci, P. Marino, M. Morello, G. Punzi, L. Ristori, F. Spinella, S. Stracka, J. Walsh
{"title":"Real-time track reconstruction during readout using an artificial retina architecture","authors":"F. Bedeschi, R. Cenci, P. Marino, M. Morello, G. Punzi, L. Ristori, F. Spinella, S. Stracka, J. Walsh","doi":"10.1109/NSSMIC.2016.8069933","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069933","url":null,"abstract":"We present the results of a study of the feasibility of implementing real-time track reconstruction within the framework of a pre-existing readout system, using the “Artificial Retina” approach. This is the first attempt at building a complete medium-size prototype of this kind (comprising about 8M Logic Elements, distributed on several separate boards), operating it continuously at its limit speed. This study emphasizes logic architecture, correct operation, size, and compatibility with a standard readout framework, to explore its useability as an add-on to a conventional readout system. For this reason we have chosen for implementation a moderate-cost, moderate-speed board already in use in the data acquisition of an existing HEP experiment. Our choice fell on the readout boards currently in use by the NA62 experiment (TEL62), each equipped with 5 Altera Stratix III FPGAs and 4 Gbit/s ethernet interface. We have reprogrammed the board firmware in two different ways, to make the boards behave as the two main blocks of a AR system (switch system, and cellular processor farm). They are interfaced via the front panel, inverting their normal data flow path, by custom interconnection boards, and devoped in internal sytem for continuous feeding of data in order to test them at their maximum achievable speed. We report the results of extensive tests perfomed with this prototype, and discuss their implications regarding the applicability of the “retina architecture” to faster, and custom-developed real-time processors.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126477804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myeong-Hun Jeong, C. Sullivan, Michael Cheng, Shaowen Wang
{"title":"Minimization of the impact of sensor velocity on the probability of source detection using geographically weighted methods","authors":"Myeong-Hun Jeong, C. Sullivan, Michael Cheng, Shaowen Wang","doi":"10.1109/NSSMIC.2016.8069703","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069703","url":null,"abstract":"Location-aware mobile sensors have fundamentally changed the ways radiation levels are detected and tracked. These changes have raised many exciting research questions related to nuclear forensics. This paper investigates the relationship between a mobile sensors' velocity and radiation counts. The study compares the correlations of the sensors' velocity and measurment radiation counts with a source or without a source. Geographically weighted approaches such as a moving kernel are used to identify regional variations in the relationship between variables. The experimental results present that there is a negative correlation between sensors' velocity and radiation counts with a source, while there is no statistically significant correlation without a source. These results can be used to decrease false alarm rates in a geotagged sensor network.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115821743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuma Oikawa, S. Gunji, T. Nakamori, M. Takakura, T. Ueda, Tatsuya Kishikawa, S. Daigle, J. Gaskin, B. Ramsey, C. Wilson-Hodge, R. Preece, M. McConnell, P. Bloser, J. Legere, D. Yonetoku, T. Mihara, K. Hayashida, Y. Kishimoto, S. Kishimoto, H. Takahashi, Y. Yatsu, K. Toma, T. Sakamoto
{"title":"Evaluation of a bread board model gamma-ray burst polarimeter toward installation on the international space station","authors":"Yuma Oikawa, S. Gunji, T. Nakamori, M. Takakura, T. Ueda, Tatsuya Kishikawa, S. Daigle, J. Gaskin, B. Ramsey, C. Wilson-Hodge, R. Preece, M. McConnell, P. Bloser, J. Legere, D. Yonetoku, T. Mihara, K. Hayashida, Y. Kishimoto, S. Kishimoto, H. Takahashi, Y. Yatsu, K. Toma, T. Sakamoto","doi":"10.1109/NSSMIC.2016.8069641","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069641","url":null,"abstract":"To elucidate the radiation mechanism of gamma ray bursts, we are developing the polarimeter which consists of segmented plastic scintillators and GAGG(Ce) scintillators attached with multi-anode photomultipliers and avalanche photodiodes, respectively. Constructing the bread board model with 36 pieces of plastic scintillator and 24 pieces of GAGG(Ce) scintillator, we have carried out the beam experiments at the KEK Photon Factory in Japan. At the same time, we carried out also computer simulation and we compared the experimental data with results of simulations. As the results, it was recognized that the modulation factor by the experiments is consistent with that by the simulations. On the other hand, though the detection efficiency obtained by the experiments is in rough agreement with that by the simulation, the value of the detection efficiency can not be well explained reasonably. This discrepancy is likely due to the incomplete energy calibration of the plastic scintillators.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131353260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Canot, O. Kochebina, M. Alokhina, P. Abbon, J. Bard, G. Tauzin, D. Yvon, Viatcheslav Sharyy
{"title":"Development of the fast and efficient gamma detector using cherenkov light","authors":"C. Canot, O. Kochebina, M. Alokhina, P. Abbon, J. Bard, G. Tauzin, D. Yvon, Viatcheslav Sharyy","doi":"10.1109/NSSMIC.2016.8069926","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069926","url":null,"abstract":"In this presentation we describe the development of a gamma detector using Cherenkov-only light. Such a device is foreseen for the detection of 511 keV photons from the positron annihilation and provides simultaneously the extremely high resolution in time and large efficiency. The main application of such a detector is the positron detection using the time-of-flight (TOF) technique, which plays an important role in the positron emission tomography (PET). It has an application in the material science for the positron annihilation lifetime spectroscopy technique and could be important for the particle identification in high energy physics. The gamma detector consists of a PbF2 crystal coupled to a micro-channelplate photo-multiplier (MCP-PMT). The ability to detect 511 keV photons by such crystal has been demonstrated, but detection efficiency is found to be rather small, less then 10% [1], due to the limited number of photons produced by the Cherenkov effect. The low efficiency is a major limiting factor for making very fast TOF PET devices. We propose an innovative solution to overtake this limitation and reach simultaneously resolution in time better than 100 ps (FWHM) and the detection efficiency of about 50%. We describe the results of the first test of a complete detector chain with radioactive positrons source 22Na.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132456203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Afterglow artifacts correction for ultra-fast tomography acquisition by synchrotron radiation","authors":"K. Z. Zefreh","doi":"10.1109/NSSMIC.2016.8069830","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069830","url":null,"abstract":"The availability of synchrotron-generated high-flux and high-energy x-rays has significantly reduced the acquisition time a tomographic scan which allows following dynamic processes in 4D (3D space + time). In the ultra-fast endstation usually a scintillator is used to convert X-ray to visible photons that can be detected by the camera. However, this conversion is not ideal and the scintillator decays exponentially with afterglow. Afterglow can cause resolution degradation and artifacts (such as ring and band) especially with high rotation speed. Performing many ultra-fast scans at the TOMCAT beamline with different acquisition rate, we demonstrate how the acquisition time effects on the projection data and reconstructed images. Based on the acquired dataset and exploited realistic model for afterglow, we propose a correction method to remove afterglow from the projections which improves the reconstruction visually and quantitatively.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130012766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}