2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)最新文献_第10页

Direct PET reconstruction of regional binding potentials 区域结合电位的直接PET重建

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069457

P. Gravel, J. Soucy, A. Reader

{"title":"Direct PET reconstruction of regional binding potentials","authors":"P. Gravel, J. Soucy, A. Reader","doi":"10.1109/NSSMIC.2016.8069457","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069457","url":null,"abstract":"This work evaluates a maximum likelihood parameter estimation method for regions-of-interest (ML-ROI) when incorporated in a direct 4D PET image reconstruction framework including the simplified reference tissue model with the basis function method (SRTM-BFM) tracer kinetic model. The ML-ROI algorithm has been evaluated for the usual task of estimating the radioactivity concentration for ROI spatial-bases compared to voxels. We therefore extend the application of this method to include the direct estimation of binding potential (BP) values on simulated 2D+time data sets (with use of [11C]raclopride time-activity curves (TACs) from real data). The performance of the proposed method is evaluated by comparing BP estimates with those obtained from a conventional post reconstruction approach, as well as the original ML-ROI method. It is shown that the use of ROIs as spatial basis functions leads to much lower %RMSE for BP regional estimates (%RMSE reduced by a factor of 2 or more), and furthermore using direct BP estimation in conjunction with ROI spatial basis functions reduces the still further. However, the major improvement is from the use of ROI spatial basis functions, rather than the use of direct kinetic parameter estimation. On the other hand, the considerable time gained (2 orders of magnitude) makes it a potential candidate for routine application.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125593519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen beam extraction of penning ion source for compact neutron generator 紧凑型中子发生器penning离子源的氢束提取

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069714

C. Lee, D. Chang, B. Oh, J. Son, Yong-Kyun Kim

引用次数: 0

A portable fast-neutron imager with 6Li-containing scintillators 携带6li闪烁体的便携式快中子成像仪

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069834

Toru Matsumura, T. Shinkawa

引用次数: 0

Optimization of pinhole aperture size of a combined MPH/fanbeam SPECT system for I-123 DAT imaging 用于I-123数据成像的MPH/扇束SPECT系统的针孔孔径尺寸优化

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069532

A. Könik, J. M. Mukherjee, Soumyanil Banerjee, J. De Beenhouwer, G. Zubal, M. King

{"title":"Optimization of pinhole aperture size of a combined MPH/fanbeam SPECT system for I-123 DAT imaging","authors":"A. Könik, J. M. Mukherjee, Soumyanil Banerjee, J. De Beenhouwer, G. Zubal, M. King","doi":"10.1109/NSSMIC.2016.8069532","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069532","url":null,"abstract":"We proposed an inexpensive method to improve the performance of the conventional dual-camera SPECT systems for I-123 dopamine transporter (DAT) imaging for Parkinson Disease. In this method, one of the collimators is replaced with a specifically designed multi-pinhole (MPH) collimator, thus performing combined MPH/Fanbeam acquisition. The MPH consists of 9 pinholes focusing to the central brain and covering a cylindrical field of view (diameter: 12cm and height: 8cm), which includes the striatum. We present here our Monte Carlo simulation work investigating the optimal aperture size for the striatal binding ratio (SBR) and caudate/putamen ratio (C/P). Projections of the XCAT brain phantom were obtained for a range of aperture sizes (radius:1–5 mm, with increments of 1mm). Multiple noise realizations were simulated for each aperture size at realistic count levels. Reconstructions from MPH, Fanbeam and combined MPH/Fanbeam systems were obtained for various numbers of iterations. For SBR and C/P calculations activities within the striatum were estimated for a range of region of interests. Normalized root mean square errors (NRMSE) of the SBR and C/P measurements were obtained for the Fanbeam and combined MPH/Fanbeam reconstructions at different iterations and VOIs, using custom made and clinically employed quantitative analysis software. Our preliminary results suggest that an aperture radius of 2-3 mm for the MPH component yields both visually and quantitatively better estimations for the MPH/Fanbeam reconstructions.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"4 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114113848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Development and deployment of a fully parameterized fast Monte Carlo simulation in LHCb 在LHCb中开发和部署一个全参数化的快速蒙特卡罗模拟

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069894

B. Siddi

{"title":"Development and deployment of a fully parameterized fast Monte Carlo simulation in LHCb","authors":"B. Siddi","doi":"10.1109/NSSMIC.2016.8069894","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069894","url":null,"abstract":"Faster alternatives to a full, GEANT4-based simulation are being pursued within LHCb experiment. In this context the integration of the Delphes toolkit in the LHCb simulation framework is intended to provide a fully parameterized option. Delphes is a modular software designed to perform fast simulations by propagating stable particles using a parametric approach and providing reconstructed physical objects as output. It includes propagation inside a magnetic field and parameterized response for tracking and muon systems as well as calorimetric response. Particle energies are computed by smearing the initial visible particles momenta according to detector resolution in a highly-customizable way. Delphes was initially designed for general-purpose experiments such as ATLAS and CMS where is already used. The present contribution illustrates the different aspect of the integration of the Delphes toolkit in Gauss, the LHCb simulation framework. Technically the particle transport performed by GEANT4 and subsequent mimicking of detector response and reconstruction has been replaced with a parametric response of the various detector elements. The implementation required extension to Delphes itself to constrain the particle transport inside the spectrometer acceptance, in order to match the LHCb dipole magnetic field. The configuration of various parameterizations of resolution and efficiency (charged particle tracking, mis-identification rate of particle identification algorithms, calorimeter, trigger response) is also a major aspect of the work to provide a fully functional simulation system. The output of the resulting fast simulation is formatted in such a way that can be used in the LHCb physics analysis framework. The status of the integration of Delphes is given.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114195244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lithium foil gas-filled neutron detector using microstrip electrodes 采用微带电极的锂箔充气中子探测器

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069790

Nathaniel S. Edwards, B. Montag, L. C. Henson, S. Bellinger, R. Fronk, M. Reichenberger, D. Mcgregor

{"title":"Lithium foil gas-filled neutron detector using microstrip electrodes","authors":"Nathaniel S. Edwards, B. Montag, L. C. Henson, S. Bellinger, R. Fronk, M. Reichenberger, D. Mcgregor","doi":"10.1109/NSSMIC.2016.8069790","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069790","url":null,"abstract":"Microstrip electrodes have been fabricated and combined with one and five suspended 6Li foils positioned within a pressurized, gas-filled chamber to create a suspended foil microstrip neutron detector. This new detector offers a mechanically and electrically robust alternative to multi-wire proportional counters. Incident neutrons are converted into charged-particle reaction products that ionize the backfill gas. Charge carriers produced from the ionization of the backfill gas drift toward their respectively-charged electrodes due to the influence of the electric field formed from the potential difference between the drift electrode and the microstrip electrode anode and cathode strips. Gas multiplication occurs as electrons approach the surface of the microstrip electrode resulting in an increase in signal amplitude. Suspended foil microstrip neutron detectors containing one and five suspended 6Li foils were simulated using MCNP6 and compared to experimental results. The measured count rates from a moderated 26-ng 252Cf source positioned 18 cm from microstrip neutron detectors equipped with one and five suspended 6Li foils were 3.25 ± 0.04 and 10.62 ± 0.14 counts per second, respectively. The intrinsic thermal neutron detection efficiency of each detector was 4.02 ± 0.04% and 14.58 ± 0.11% for one and five suspended 6Li foils, respectively.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120922990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Empirical noise power spectrum based on the image subtraction in radiography imaging 基于图像减法的放射成像经验噪声功率谱

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069476

Dong Sik Kim, Eunae Lee

{"title":"Empirical noise power spectrum based on the image subtraction in radiography imaging","authors":"Dong Sik Kim, Eunae Lee","doi":"10.1109/NSSMIC.2016.8069476","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069476","url":null,"abstract":"In order to measure the noise power spectrum (NPS) of a radiography detector from acquired images without any object, a subtraction-based algorithm, in which the input image is subtracted from another image acquired at the same exposure condition, is usually used to alleviate the fixed pattern noise influence. However, depending on variations in the x-ray tube and the readout circuits in the detector, the acquired images show nonuniform statistics and thus selecting an appropriate image pair from a given image set is important for a stable measurement of NPS. In order to select a good image pair for measuring an accurate normalized NPS (NNPS), a measurement method is proposed based on selecting an image pair from comparing the signal-to-noise ratios, which are obtained from the subtracted image. For the comparison, a commutative relationship as a sufficient condition for the accurate NNPS is considered. For a given image pair, the proposed method can provide a degree of accuracy of the empirical NNPS. For real x-ray images acquired from an indirect radiography detector, the proposed method is tested and shows stable measuring results for a set of images.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120960854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A novel electronics for large scale SiPM array readout and advanced PET applications 用于大规模SiPM阵列读出和先进PET应用的新型电子器件

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069885

Zhixiang Zhao, Qiu Huang, T. Sui, Jianfeng Xu, Q. Peng

引用次数: 0

Does energy non-linearity affect noise estimates from Monte Carlo simulations of X-ray imaging detectors? 能量非线性是否影响从蒙特卡罗模拟x射线成像探测器的噪声估计?

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069415

A. Badano

{"title":"Does energy non-linearity affect noise estimates from Monte Carlo simulations of X-ray imaging detectors?","authors":"A. Badano","doi":"10.1109/NSSMIC.2016.8069415","DOIUrl":"https://doi.org/10.1109/NSSMIC.2016.8069415","url":null,"abstract":"Publicly available Monte Carlo simulation packages for light transport in scintillator-based x-ray imaging detectors utilize a linear yield model. However, scintillators are known to be non-linear in the lower end of the energy range. Is this assumption reasonable for x-ray imaging simulations? We modified a freely available Monte Carlo package for modeling x-ray scintillators (MANTIS) to compare a linear versus a nonlinear optical yield model. We report simulations in the diagnostic x-ray energy range for a CsI:Tl. To determine the effect of the light yield model on imaging performance, we calculated the distribution of signal outputs characterized by the information or Swank factor. We find that the choice of yield model plays a significant role in the outcome statistics increasing the intensity of lower energy peaks favored by the non-linear model. This observation is confirmed by the results for the Swank factor with larger values for the non-linear models for an increase with respect to the linear model results of 42 and 26% for a high-resolution and a high-light-output model respectively. Our findings indicate that the assumption of linear light yield in Monte Carlo simulations of imaging detectors might introduce a significant bias in the estimates of noise as expressed by the Swank factor. More research is needed to implement realistic nonlinear yield models, to calculate the effect on realistic simulations including x-ray spectra of interest, and to experimentally validate these models.","PeriodicalId":184587,"journal":{"name":"2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121023173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neutron spallation to enhance muon scattering tomography 中子散裂增强介子散射层析成像

2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) Pub Date : 2016-10-01 DOI: 10.1109/NSSMIC.2016.8069702

C. Grove, C. Eldridge, J. Burns, C. Steer, G. Chapman, A. Lohstroh

引用次数: 0