Medical Journal of Dr. D.Y. Patil Vidyapeeth最新文献

{"title":"Serum Gamma-Glutamyl Transferase and C-Reactive Protein in Essential Hypertension","authors":"Richa Awasthi, P. T. Manger, Vivek Katiyar","doi":"10.4103/mjdrdypu.mjdrdypu_164_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_164_23","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Hypertension is known to be one of the major causes of the global burden of many diseases. It is proving to be a critical medical and public health issue. Previous studies have drawn inconsistent conclusions about the risk of hypertension and its association with gamma-glutamyl transferase and C-reactive protein (CRP). CRP is a marker of systemic inflammation and has been postulated to increase the risk of hypertension. Gamma-glutamyl transferase catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide, or water. This study was undertaken to evaluate gamma-glutamyl transferase and CRP in essential hypertension and determine the association of these parameters with hypertension, if any.\u0000 \u0000 \u0000 \u0000 A total of 104 subjects (52 hypertensive cases and 52 healthy controls) between the ages of 30 and 50 were recruited after imposing certain inclusion and exclusion criteria. Gamma-glutamyl transferase and CRP were estimated using commercially available kits. All the data were tested at a 5% level of significance.\u0000 \u0000 \u0000 \u0000 Mean levels of gamma-glutamyl transferase and CRP were found to be significantly increased in patients with essential hypertension compared to controls. Elevated levels of gamma-glutamyl transferase and CRP are associated with oxidative stress and inflammation, which are in turn considered to be major factors involved in the pathogenesis of hypertension.\u0000 \u0000 \u0000 \u0000 In conclusion, our study suggests that gamma-glutamyl transferase and C-reactive protein are independently associated with hypertension.\u0000","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":" 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promotion of Religious Texts in Scientific Literature: Relevance and Validity","authors":"Himadri Bal","doi":"10.4103/mjdrdypu.mjdrdypu_979_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_979_23","url":null,"abstract":"","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141131540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound in Bone Quality Screening: From the Perspective of Osteoporosis","authors":"Sara Rosa de Sousa Andrade, Waldemar Naves do Amaral, Maria Rita de Sousa Silva, Manisha A. Rathi, Vinicius de Almeida Lima, Mayara Rios Leite Macedo","doi":"10.4103/mjdrdypu.mjdrdypu_1079_22","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_1079_22","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Among Brazilians, 4.4% of population has osteoporosis, and the characteristic population with the disease is women above 45 years. Monitoring bone mineralization from an early age becomes a preventive factor essential for those with a family history of osteoporosis or vulnerable population to develop osteoporosis. It is essential to use techniques that are affordable and easily available with high reliability. Quantitative ultrasound (QUS) can be one of these techniques.\u0000 \u0000 \u0000 \u0000 The objective of the study was to analyze the importance of phalanx ultrasound (US) as a tracking element of the bone quality, accurately establish the diagnostic tests as bone quality, define a nomogram of bone quality, build bone quality normality curve, and establish the pathological risk cutoff score according to the age group.\u0000 \u0000 \u0000 \u0000 In this descriptive, analytical, cross-sectional study, 125 women who met the inclusion criteria were selected. They were divided into four groups according to their age: group 1 (G1): 30 to 39 years; group 2 (G2): 40 to 49 years; group 3 (G3): 50 to 59 years; and group 4 (G4): 60 years and above. All the participants underwent phalanx US and dual-energy X-ray absorptiometry (DEXA). The Ultrasound Bone Profile Index (UBPI) was found, and the phalanx US and sensitivity of the same technique were determined.\u0000 \u0000 \u0000 \u0000 UBPI at the phalanx was compared with DEXA, and the sensitivity of the test was found to be 80% for G1 and 100% for G2, G3, and G4. Regarding femur DEXA, the sensitivity of the test was 90% for G1 and 100% for G2, G3, and G4. There was a significant inverse correlation observed between age and bone quality. This result includes an early decrease in bone quality, starting in the fertile period of women. The cutoff score for pathological risk was as follows: G1: 0.68 ± 0.23; G2: 0.64 ± 0.28; G3: 0.54 ± 0.37; and G4: 0.32 ± 0.30.\u0000 \u0000 \u0000 \u0000 Phalanx US proved to be a highly effective method as an osteoporosis tracking element in terms of bone quality evaluation, hence can be used as a screening tool for early diagnosis among the female population.\u0000","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":" 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141130411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Incidence of Awareness under Anesthesia and After Effects: Case Report","authors":"A. Bagle, Shahbaz Hasnain","doi":"10.4103/mjdrdypu.mjdrdypu_691_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_691_23","url":null,"abstract":"ABSTRACT\u0000 \u0000 Awareness of one’s surroundings and operations on the body is a horrifying experience for the person undergoing surgery under general anesthesia. Here we are reporting a case of a 31-year-old female patient who reported awareness under general anesthesia. During postoperative follow-up, the patient complained of memories of events while under anesthesia. It’s important to recognize the contributing elements that can lead to perioperative awareness in a surgical setting. When awareness is suspected or proven, the patient needs support during the healing process and during the subsequent psychological aftereffects.","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141131900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia Management of a Geriatric Patient with a Left Ventricular Ejection Fraction of 15% with Multiple Comorbidities for Spine Fixation","authors":"Sandip Baheti, Runjhun Jain","doi":"10.4103/mjdrdypu.mjdrdypu_630_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_630_23","url":null,"abstract":"","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141140361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bhagavad Gita and Psychotherapy: Applications and Handling Concerns","authors":"Vasu Mishra, SurendraS Rajpurohit, N. Nebhinani","doi":"10.4103/mjdrdypu.mjdrdypu_37_24","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_37_24","url":null,"abstract":"","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"25 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141134122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathologic Analysis of Malabsorption Syndrome in a Tertiary Care Center in South India","authors":"Nidhya Ganesan, S. Shrinnivi, R. Shivani, R. Kartikayan","doi":"10.4103/mjdrdypu.mjdrdypu_402_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_402_23","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Malabsorption syndrome is an umbrella term for manifestations consisting of diarrhea, steatorrhea, malnutrition, unexplained weight loss, persistent or recurrent abdominal pain, and anemia. Celiac disease and Tropical sprue remain the two important causes among many more.\u0000 \u0000 \u0000 \u0000 The objectives of this study were to assess the spectrum of histological features of malabsorption at a tertiary care center and to correlate the clinical, endoscopic, and histological features between the various etiologies. Biopsy specimens of 547 subjects formed the sample for this institutional-based, retrospective research. All subjects who had a clinical diagnosis of malabsorption and underwent subsequent endoscopic evaluation along with biopsy were considered. The hematoxylin and eosin-stained sections were analyzed for villous architecture and intraepithelial lymphocytes (IELs). The histopathological findings were further correlated with the endoscopic findings. Data thus obtained were statistically analyzed using Microsoft Excel for Windows (2010).\u0000 \u0000 \u0000 \u0000 The mean age of the subjects was 46.65 ± 17.31 years and with 330 males (60.33%) and 217 female (39.63%) subjects. Chronic diarrhea was the major presenting symptom in 95% of the subjects (n = 520). Normal villous architecture was noted in 68.19%, while the remaining cases showed varying degrees of atrophy ranging from mild in 27.61% (n = 151) to moderate in 2.56% (n = 14) to severe in 1.65% (n = 9). IELs were noted in 70.78% of cases.\u0000 \u0000 \u0000 \u0000 Histopathological findings, when analyzed, showed intraepithelial lymphocytosis as the major diagnosis in 34.19% of cases (n = 187), followed by tropical sprue in 19.56% (n = 107) cases. The pathology was nonspecific in about 13.89% (n = 76).\u0000","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"51 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141139803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editors, Reviewers, Rag-Pickers, and Garbage-Handlers: Similar Challenges!","authors":"A. Banerjee","doi":"10.4103/mjdrdypu.mjdrdypu_249_24","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_249_24","url":null,"abstract":"","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"50 s248","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141134873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Classic Ketogenic Diet Versus Modified Atkins Diet over Electro-Encephalogram Findings in Children with Refractory Epilepsy","authors":"Vaishali Deshpande, Purnima Prabhu, V. Udani, S. Agarkhedkar","doi":"10.4103/mjdrdypu.mjdrdypu_726_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_726_23","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Ketogenic diet (KD) is well known for control of refractory epilepsy. We wanted to study the effect of the two types of diets: classic KD and modified Atkins diet (MAD) with Indian foods to children of refractory epilepsy on electroencephalogram (EEG).\u0000 \u0000 \u0000 \u0000 To determine the effect of KD on EEG on children with refractory epilepsy.\u0000 \u0000 \u0000 \u0000 Ethics Committee approval was taken for randomized controlled trials. Sixty-five children of refractory epilepsy of 6 months to 12 years’ age from two tertiary care teaching institutes, of Pune and Mumbai, were selected and allocated to one of the two types of diets, classic KD and MAD, and followed over a period of 6 months. EEG was done in the beginning, at 3 months, and at 6 months of completion of therapy with standard techniques.\u0000 \u0000 \u0000 \u0000 The relationship of EEG findings at 3 months follow-up was statistically non-significant, but at the end of 6 months, when overall improved activity on EEG was compared, it had a significant difference of P-value = 0.01, stating KD better than MAD.\u0000 \u0000 \u0000 \u0000 Classic KD is better than MAD.\u0000","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"47 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141142356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are We Equipped or Still Unprepared to Act Early to Avoid Misuse or Overuse of Resources: A Perspective in View of Recent Conjunctivitis Surge","authors":"Preethy Edavaloth, N. Gandham, S. Mirza","doi":"10.4103/mjdrdypu.mjdrdypu_758_23","DOIUrl":"https://doi.org/10.4103/mjdrdypu.mjdrdypu_758_23","url":null,"abstract":"","PeriodicalId":18412,"journal":{"name":"Medical Journal of Dr. D.Y. Patil Vidyapeeth","volume":"56 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141133954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}