International Journal of Medical Laboratory最新文献

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The Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referred to Amir al-Mu'minin Hospital of Gerash City, Fars Province, Iran 转介至伊朗法尔斯省格拉什市Amir al-Mu'minin医院的孕妇妊娠期糖尿病患病率
International Journal of Medical Laboratory Pub Date : 2021-08-10 DOI: 10.18502/ijml.v8i3.7322
E. Rezaee, F. Mohammadi, Mohammad Javad Boozhmehrani, P. Bagheri
{"title":"The Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referred to Amir al-Mu'minin Hospital of Gerash City, Fars Province, Iran","authors":"E. Rezaee, F. Mohammadi, Mohammad Javad Boozhmehrani, P. Bagheri","doi":"10.18502/ijml.v8i3.7322","DOIUrl":"https://doi.org/10.18502/ijml.v8i3.7322","url":null,"abstract":"Background and Aims: The increasing number of pregnant women being diagnosed as having gestational diabetes mellitus (GDM) and  lead health care providers to develop reliable screening protocols and know the exact worldwide epidemiology of the disease. This study seeks to obtain data that will help to improve the epidemiologic knowledge about this disease. \u0000Materials and Methods: This cross-sectional study was performed on 953 pregnant women seeking routine prenatal screening tests. Participants participate with using Carpenter-Coustan criteria in the study. Statistical analysis was performed using SPSS software. \u0000Results and Conclusions: Among 953 pregnant women , 38 participants (4%) were detected to have GDM . Fifty percent of patients in the study were overweight .The data showed a significant difference in the mean age between the diabetic and non-diabetic groups. The high prevalence of GDM in young Iranian pregnant women may emphasize the need for early diagnosis and treatment to avoid adverse outcomes associated with GDM.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133905762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Effect of Thymol on Renal Toxicity Induced by Mercury Chloride in Rats 百里香酚对氯化汞所致大鼠肾毒性的影响
International Journal of Medical Laboratory Pub Date : 2021-08-10 DOI: 10.18502/ijml.v8i3.7335
H. Jamshidi, Faeze Taheri
{"title":"The Effect of Thymol on Renal Toxicity Induced by Mercury Chloride in Rats","authors":"H. Jamshidi, Faeze Taheri","doi":"10.18502/ijml.v8i3.7335","DOIUrl":"https://doi.org/10.18502/ijml.v8i3.7335","url":null,"abstract":"Background and Aims: Mercuric chloride is highly toxic once absorbed into the bloodstream, especially the kidneys in which it is collected. Mercury chloride increases hydrogen peroxide and enhances the destruction of protective enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPX), leading to oxidative stress. Besides, thymol has anti-oxidant effects and can increase the activity of SOD and GPX. This study aims to evaluate the efficacy of thymol on mercury chloride-induced toxicity. \u0000Materials and Methods: In this study, 30 rats, consisting of 6 groups of 5, were used. Control group receiving a single dose of 0.5 mg/kg mercuric chloride for 15 days, third, fourth, and fifth group received intraperitoneal injection of mercuric chloride at a dose of 0.5 mg/kg for 15 days plus thymol at a dose of 10, 30, 50 mg/kg. The sixth group received mercuric chloride at a dose of 0.5 mg/kg for 15 days plus thymol at 30 mg/kg per day for ten days. \u0000Results: Results showed a significant difference in the activity of catalase enzyme in kidney tissue samples test. According to the results of SOD, there is a significant difference between the group of corn oil and the group of mercury chloride and between the group of mercury chloride and the group that receives thymol at a dose of 10, 30, 50 mg/kg (p ≤ 0.05). \u0000Conclusions: It can be concluded that mercury chloride-induced kidney toxicity and thymol have anti-oxidant protective effects for SOD and GPX.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133890649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of Blood Biochemical Markers and Anthropometric Parameters in Different Fatty Liver Grades 不同级别脂肪肝患者血液生化指标及人体测量参数的比较
International Journal of Medical Laboratory Pub Date : 2021-08-10 DOI: 10.18502/ijml.v8i3.7326
Narges Jani, M. Azari, S. J. Ghalekohneh, Mahdie Hemati, J. Mohiti-ardekani, A. Nadjarzadeh, Yousof Naghiaee
{"title":"Comparison of Blood Biochemical Markers and Anthropometric Parameters in Different Fatty Liver Grades","authors":"Narges Jani, M. Azari, S. J. Ghalekohneh, Mahdie Hemati, J. Mohiti-ardekani, A. Nadjarzadeh, Yousof Naghiaee","doi":"10.18502/ijml.v8i3.7326","DOIUrl":"https://doi.org/10.18502/ijml.v8i3.7326","url":null,"abstract":"Background and Aims: Obesity and hyperlipidemia, diabetes, and malnutrition are among the causes of fatty liver disease. This study compares blood biochemical markers and anthropometric parameters in different grades of fatty liver. \u0000Materials and Methods: In this descriptive cross-sectional study, 73 fatty liver patients were studied. The degree of fatty liver disease was divided into three grades on ultrasonography. Anthropometric parameters BMI, waist circumstance, height, weight in the fasting state were evaluated according to the standard protocols. The blood samples were taken and biochemical variables fasting blood sugar, serum glutamic-oxaloacetic transaminase (SGOT), Serum glutamic-pyruvic transaminase (SGPT), calcium, phosphorus, low density lipoprotein (LDL), cholesterol, triglyceride, and others were examined with photometric and HPLC methods. \u0000Results: Statistical analysis was significant between grades 1 and 3 of fatty liver (p = 0.006) and body mass index between grades 1 and 3 of fatty liver (p = 0.003). Comparing SGOT between different grades did not show any significant differences. However, comparing Bili Total indicated a significant difference between grades 1 and 2 and 1 and 3. Moreover, statistical analysis of qualitative variables, such as gender, hypertension, smoking, drug, alcohol, heart disease, stomach disease, and kidney disease, was not statistically significant between the three fatty liver groups. Median ± IQR had a significant difference for SGOT and Bili Total (p < 0.05). \u0000Conclusion: This study showed the significance of BMI, waist circumstance, and bilirubin factors in different grades of fatty liver. Monitoring BMI, waist circumstance, and bilirubin factors will be useful for susceptible people to non-alcoholic fatty liver disease.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130980462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of Human Cystic Echinococcosis in Sanandaj City, Kurdistan Province, Western Iran 伊朗西部库尔德斯坦省萨南达杰市人类囊性棘球蚴病的血清患病率
International Journal of Medical Laboratory Pub Date : 2021-08-10 DOI: 10.18502/ijml.v8i3.7325
N. Nazari, Tooran Nayeri, F. Hazrati
{"title":"Seroprevalence of Human Cystic Echinococcosis in Sanandaj City, Kurdistan Province, Western Iran","authors":"N. Nazari, Tooran Nayeri, F. Hazrati","doi":"10.18502/ijml.v8i3.7325","DOIUrl":"https://doi.org/10.18502/ijml.v8i3.7325","url":null,"abstract":"Background and Aims: Echinococcus granulosus (E. granulosus) is a cestode parasite that causes cystic hydatid disease in humans worldwide. Iran is one of the endemic regions for infection that indicate the importance and presence of infection in this country. Therefore, the current research aimed to characterize the seroprevalence of human cystic echinococcosis in Sanandaj city, Kurdistan province, western Iran. \u0000Materials and methods: Totally, 500 serum samples were collected from patients referred to different health centers in Sanandaj city using cluster sampling in 2018-2019. All the sera were examined using the enzyme-linked immunosorbent assay test. \u0000Results: The seroprevalence of human hydatidosis was reported at 2.2% by ELISA test in Sanandaj city. This rate was 9 (1.9%) in women and 2 (0.4) in men. The age group of 20-30 years old had the highest positivity rate (1.0%). Also, the subjects that consumed home slaughtered meat had the highest infection rate at 4 (0.8%). There was no significant difference regarding factors studied such as sex, education, residence, consumed water, keeping a dog, and the seropositivity. \u0000Conclusions: Seroprevalence of human cystic echinococcosis in Sanandaj city is lower than the general prevalence in Iran. Our research team hopes to provide accurate data on the prevalence of hydatidosis in Sanandaj encourage more extensive research to help prevent this parasite in Iran and worldwide.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128370256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and Paraclinical Characteristics of 57 Deceased COVID-19 Patients in Tehran, Iran: A Retrospective Observational Study 伊朗德黑兰57例COVID-19死亡患者的临床和临床旁特征:一项回顾性观察研究
International Journal of Medical Laboratory Pub Date : 2021-03-09 DOI: 10.18502/IJML.V8I1.5667
Niayesh Mohebbi, Sara Pakzad Karamad, K. Moghadam, Mohamadreza Jafary, Poorya Rajabi, A. Nejat, A. Kasaeian, Mona Talaschian
{"title":"Clinical and Paraclinical Characteristics of 57 Deceased COVID-19 Patients in Tehran, Iran: A Retrospective Observational Study","authors":"Niayesh Mohebbi, Sara Pakzad Karamad, K. Moghadam, Mohamadreza Jafary, Poorya Rajabi, A. Nejat, A. Kasaeian, Mona Talaschian","doi":"10.18502/IJML.V8I1.5667","DOIUrl":"https://doi.org/10.18502/IJML.V8I1.5667","url":null,"abstract":"Background and Aims: In 2019, a novel coronavirus called SARS-COV-2 spread throughout the world, causing a pandemic a few months later. As the virus is not well-known and highly contagious, it is important to observe patients for all possible symptoms and comorbidities. This study aimed to demonstrate some demographic, clinical, and paraclinical features of the deceased patients with COVID-19 in Iran. Materials and Methods: A retrospective observational study was designed to demonstrate the clinical and paraclinical features of deceased patients who had a positive real time-polymerase chain reaction test result for COVID-19. The study included all COVID-19 patients who visited Shariati Hospital, Tehran, Iran, from February 20th until May 20th, 2020. All data were analyzed using IBM SPSS version 21 (Mann-Whitney or Fisher’s test). \u0000 Results: The patients had a mean age of 63.86 ± 16.428, and most were males (59.65%). Diabetes and hypertension were the most frequent comorbidities. The most common symptoms among the patients were dyspnea (64.91%), weakness (61.40%), fever (60.71%), and having ground-glass opacities in the CT scans (85.96%). There was also a rise in lactate dehydrogenase, serum ferritin, D-dimer, and procalcitonin. \u0000Conclusions: Older COVID-19 patients are more likely to get more severe forms of the disease. Most of the deceased COVID-19 patients had ground-glass opacities in their CT scans. Dyspnea, fatigue, and fever were the most frequent symptoms. Hypertension and diabetes were the most important comorbidities. There was almost no significant difference between the two genders regarding clinical and paraclinical symptoms.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121947564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Detection of Human Cytomegalovirus in Semen of infertile Men in Tehran 德黑兰不育男性精液中巨细胞病毒的分子检测
International Journal of Medical Laboratory Pub Date : 2021-03-09 DOI: 10.18502/IJML.V8I1.5673
M. Moradi, Somayeh Sadat Moochani, N. Yamini, D. Javanmard, Arezoo Marjani, A. Tabibzadeh, A. Tavakoli, S. Monavari
{"title":"Molecular Detection of Human Cytomegalovirus in Semen of infertile Men in Tehran","authors":"M. Moradi, Somayeh Sadat Moochani, N. Yamini, D. Javanmard, Arezoo Marjani, A. Tabibzadeh, A. Tavakoli, S. Monavari","doi":"10.18502/IJML.V8I1.5673","DOIUrl":"https://doi.org/10.18502/IJML.V8I1.5673","url":null,"abstract":"Background and Aims: Human cytomegalovirus (HCMV) can induce latency and evade the immune system. The latent virus can reactive later in older ages and due to immunosuppressive conditions. Sexually transmitted diseases and viruses can influence the male reproductive system, and members of the Herpesviridae family are one of these important viruses. Regarding the importance of herpesviruses, specially HCMV, this research aimed to evaluate the prevalence of HCMV in semen samples of infertile men. \u0000Materials and Methods: Semen samples were collected from infertility centers affiliated to Iran University of Medical Sciences. The chromatin state was assessed by DNA fragmentation index. Nucleic acids were extracted from the semen specimens, and a real-time polymerase chain reaction assay was performed to detect HCMV DNA. \u0000Results: Enrolled patients were 82 infertile men. The mean age of participants was 37.3 ± 6.1 years, and the mean motility and DNA fragmentation index of the samples were 33.6 ± 2 % and 27.2 ± 1.2, respectively. The prevalence of HCMV was 11%, and there was no statistically significant difference between HCMV and sperm parameters except the motility. \u0000Conclusions: HCMV infection could be important in sperm motility, and HCMV prevalence in infertile patients was 11%. Further investigations in this field can be helpful for a clear result in the future.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115758374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Which Culture System Is better for Chondrogenesis of Adipose-Derived Stem Cells ; Pellet or Micromass? 哪种培养体系更有利于脂肪干细胞的软骨形成颗粒还是微团?
International Journal of Medical Laboratory Pub Date : 2020-12-07 DOI: 10.18502/ijml.v7i4.4798
M. Teimouri, B. Hashemibeni, Mohammad Mardani, Muhammadhosein Moradi
{"title":"Which Culture System Is better for Chondrogenesis of Adipose-Derived Stem Cells ; Pellet or Micromass?","authors":"M. Teimouri, B. Hashemibeni, Mohammad Mardani, Muhammadhosein Moradi","doi":"10.18502/ijml.v7i4.4798","DOIUrl":"https://doi.org/10.18502/ijml.v7i4.4798","url":null,"abstract":"Background and Aims: The current study was conducted to compare the expression levels of collagen type Π and X during chondrogenesis of human adipose-derived mesenchymal stem cells (hADMSCs) pellet and micromass cultures.  \u0000Materials and Methods: Extracted hADMSCs were cultured until three passages and then transferred to pellet and micromass cultures in the experimental groups of day 7 and day14. For pellet and micromass cultures, aliquots of 5×105 cells/ml were centrifuged and respectively cultured in the conical tubes and droplets (12.5 µl) of the 24-well plates containing  chondrogenic medium. Realtime-polymerase chain reaction technique was performed for gene expression levels. \u0000Results: Increased expression of collagen type Π was shown in micromass day14 compared to micromass day 7, pellet day 14 (p<0.01) and pellet day 7 (p<0.001). Also, an increased expression of collagen type Π was seen in micromass day 7 and pellet day 14 compared to pellet day 7 (p< 0.05). Expression of collagen type X increased in pellet day 14 compared to micromass on days 7 and 14 (p<0.001, p<0.01) and pellet day14 compared to pellet day7 (p< 0.05). An increased expression of collagen type X was shown in pellet day 7 compared to micromass on days 7 and 14 (p<0.05). \u0000Conclusions: According to the results, higher expression of collagen type Π and lower expression of collagen type X in micromass cultures that are prepared by cell suspension play a better role during cellular condensation that leads to the formation of large nodules exhibiting cartilage-like morphology, suggests a higher efficiency for micromass cultures.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128012610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diversity of Toll-like Receptor Genes and Helicobacter Pylori Infections: A Meta-Analysis Study toll样受体基因多样性与幽门螺杆菌感染:一项meta分析研究
International Journal of Medical Laboratory Pub Date : 2020-05-10 DOI: 10.18502/ijml.v7i2.2910
H. Vaez, A. Sahebkar, A. Mohammadi, M. Arzanlou, A. Yousefi-Avarvand, F. Khademi
{"title":"Diversity of Toll-like Receptor Genes and Helicobacter Pylori Infections: A Meta-Analysis Study","authors":"H. Vaez, A. Sahebkar, A. Mohammadi, M. Arzanlou, A. Yousefi-Avarvand, F. Khademi","doi":"10.18502/ijml.v7i2.2910","DOIUrl":"https://doi.org/10.18502/ijml.v7i2.2910","url":null,"abstract":"Background and Aims: Several studies have shown that host genetic factors can be associated with the risk of developing Helicobacter pylori infections. Therefore, we evaluated the most prevalent toll-like receptors (TLRs) polymorphisms in Helicobacter pylori positive subjects and their possible role in susceptibility to Helicobacter pylori infections. Materials and Methods: Using related keywords, an independent search in the electronic databases including PubMed, Scopus, Google Scholar and ISI web of knowledge was performed to collect studies evaluating, until January 15, 2019, polymorphisms in the TLR 1 to 13 genes and their association with susceptibility to Helicobacter pylori infection. A total of 18 articles met our inclusion criteria and thus were included in the meta-analysis. Results: In this meta-analysis, a significantly increased risk of Helicobacter pylori infection was observed in subjects carrying TLR2 rs3804099 (TT vs. CC: odds ratio = 2.209, 95% CI: 1.283-3.804), TLR4 rs4986790 (A allele vs. G allele: odds ratio = 2.987, 95% CI: 1.899-4.697), TLR4 rs4986791 (C allele vs. T allele: odds ratio = 5.469, 95% CI: 13.432-8.713), TLR4 rs4986791 (CC vs. TT: odds ratio = 7.974, 95% CI: 2.682-23.706), TLR4 rs10759932 (TT vs. CC: odds ratio = 3.180, 95% CI: 1.022-9.890), TLR4 rs1927914 (C allele vs. T allele: odds ratio = 8.831, 95% CI: 4.222-18.470), and TLR9 rs352140 (CC vs. CT: odds ratio = 1.878, 95% CI: 1.071-3.290) polymorphisms. Conclusions: This meta-analysis indicated that TLR2 rs3804099, TLR4 rs4986790, TLR4 rs4986791, TLR4 rs10759932, TLR4 rs1927914 and TLR9 rs352140 polymorphisms are associated with increased susceptibility to Helicobacter pylori infections.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122068378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Elevated Non-HDL Cholesterol among Patients with Diabetes in An Iranian Population 伊朗人群中糖尿病患者非高密度脂蛋白胆固醇升高的患病率
International Journal of Medical Laboratory Pub Date : 2020-05-10 DOI: 10.18502/ijml.v7i2.2909
Asma Kheirollahi, A. Karkhaneh
{"title":"Prevalence of Elevated Non-HDL Cholesterol among Patients with Diabetes in An Iranian Population","authors":"Asma Kheirollahi, A. Karkhaneh","doi":"10.18502/ijml.v7i2.2909","DOIUrl":"https://doi.org/10.18502/ijml.v7i2.2909","url":null,"abstract":"\u0000 \u0000 \u0000Background and Aims: Non-high density lipoprotein cholesterol (non- \u0000HDL-C), which reflects all cholesterol present in potentially atherogenic lipoprotein particles, might be a useful marker of atherosclerosis in diabetic subjects. In the present study, we evaluated the prevalence of high non-HDL-C in patients with dyslipidemia in diabetic and non-diabetic subjects following LDL-C assessment as the first goal of therapy. Materials and Methods: A data set of 2142 individuals was included in the study. All values of lipid profile were compared between non-diabetic and diabetic groups and the prevalence of dyslipidemia was evaluated in two groups. \u0000Results and Conclusions: According to the results, 48% of patients with diabetes achieved combined LDL-C ≤2.5 mmol/L and non-HDL ≤3.3 mmol/L targets, and 58.2% of diabetic patients achieved LDL-C goal while only 50.2% attained non-HDL-C goal. Also, the results indicated that non-HDL-C significantly heightened in patients with diabetes. Therefore, non-HDL-C needs to be calculated as a routine assessment in patients with diabetes. \u0000 \u0000 \u0000","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130283913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
In Vitro Evaluation of Antifungal Activity of Three Traditionally Used Medicinal Plants; Umbilicus Intermedius Boiss, Cuminum Cyminum and Zingiber Officinale Extracts 三种传统药用植物抗真菌活性的体外评价脐草、茴香、生姜提取物
International Journal of Medical Laboratory Pub Date : 2019-11-10 DOI: 10.18502/ijml.v6i4.2006
Ameneh Takesh, M. Fatahinia, A. Mahmoudabadi
{"title":"In Vitro Evaluation of Antifungal Activity of Three Traditionally Used Medicinal Plants; Umbilicus Intermedius Boiss, Cuminum Cyminum and Zingiber Officinale Extracts","authors":"Ameneh Takesh, M. Fatahinia, A. Mahmoudabadi","doi":"10.18502/ijml.v6i4.2006","DOIUrl":"https://doi.org/10.18502/ijml.v6i4.2006","url":null,"abstract":"Background and Aims: The study aimed to determine the effectiveness of three medicinal plant extracts on fungi with three methods and to compare methods.  Material and methods: This study examined the antifungal properties of cumin (Cuminum cyminum L), ginger (Zingiber officinale Roscoe) and Nafe Venus (Umbilicus intermedius boiss) extracts against fungi including, Aspergillus spp., Penicillium spp., Mucor spp., Stemphylium spp., Drechslera spp., Alternaria spp., Cladosporium spp., and Aureobasidium pullulans. Furthermore, 17 candida isolates including, C. albicans, C. glabrata and C. dubliniensis were tested. In the present study two methods of disc diffusion method, agar wells diffusion method were used for assay. Then, the mixing with culture medium method was used for assessment of the antifungal activity of extracts against Alternaria sp.(as black mold), A. terreus (as hyaline mold) and C. albicans (as yeast) to compare methods as well. Results: No fungi were susceptible to extracts in disc diffusion method and agar wells diffusion method. But, this study showed that in mixing with culture medium method, cumin extract has valuable anti-fungal property and Umbilicus intermedius boiss has the inhibitory properties against the black fungi. Furthermore, it is found that mixing with culture medium method is more efficient than disc and agar well diffusion methods. Alternaria sp. and C. albicans were susceptible and resistant to all extracts.  Conclusions: it is found that mixing with culture medium method is more efficient than disc and agar well diffusion methods and inhibitory potency of the extracts varies according to the type of extraction and their concentration.","PeriodicalId":183358,"journal":{"name":"International Journal of Medical Laboratory","volume":"14 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128989731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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