Medical Journal of Indonesia最新文献_第2页

Atypical orbital primary optic nerve sheath meningioma with severe disfiguring proptosis: an alternative surgical approach 非典型眼眶原发性视神经鞘脑膜瘤伴严重畸形突出:一种替代手术入路

Medical Journal of Indonesia Pub Date : 2023-11-01 DOI: 10.13181/mji.cr.236936

Sylves Patrick, Yeap Boon Tat, Muhamad Zarif Mohd Amin, Maftuhim Addenan, Shuaibah Ab.Ghani, Hanida Hanafi

引用次数: 0

Role of a journal for the publication of doctoral dissertations 期刊发表博士论文的作用

Medical Journal of Indonesia Pub Date : 2023-10-20 DOI: 10.13181/mji.ed.237163

Harrina Erlianti Rahardjo

引用次数: 0

Accuracy of machine learning models using ultrasound images in prostate cancer diagnosis: a systematic review 使用超声图像诊断前列腺癌的机器学习模型的准确性:系统综述

Medical Journal of Indonesia Pub Date : 2023-10-20 DOI: 10.13181/mji.oa.236765

Retta Catherina Sihotang, Claudio Agustino, Ficky Huang, Dyandra Parikesit, Fakhri Rahman, Agus Rizal Ardy Hariandy Hamid

{"title":"Accuracy of machine learning models using ultrasound images in prostate cancer diagnosis: a systematic review","authors":"Retta Catherina Sihotang, Claudio Agustino, Ficky Huang, Dyandra Parikesit, Fakhri Rahman, Agus Rizal Ardy Hariandy Hamid","doi":"10.13181/mji.oa.236765","DOIUrl":"https://doi.org/10.13181/mji.oa.236765","url":null,"abstract":"BACKGROUND In prostate cancer (PCa) diagnosis, many developed machine learning (ML) models using ultrasound images show good accuracy. This study aimed to analyze the accuracy of neural network ML models in PCa diagnosis using ultrasound images. METHODS The protocol was registered with PROSPERO registration number CRD42021277309. Three reviewers independently conducted a literature search in 5 online databases (PubMed, EBSCO, Proquest, ScienceDirect, and Scopus). We included all cohort, case-control, and cross-sectional studies in English, that used neural networks ML models for PCa diagnosis in humans. Conference/review articles and studies with combination examination with magnetic resonance imaging or had no diagnostic parameters were excluded. RESULTS Of 391 titles and abstracts screened, 9 articles relevant to the study were included. Risk of bias analysis was conducted using the QUADAS-2 tool. Of the 9 articles, 5 used artificial neural networks, 1 used deep learning, 1 used recurrent neural networks, and 2 used convolutional neural networks. The included articles showed a varied area under the curve (AUC) of 0.76–0.98. Factors affecting the accuracy of artificial intelligence (AI) were the AI model, mode and type of transrectal sonography, Gleason grading, and prostate-specific antigen level. CONCLUSIONS The accuracy of neural network ML models in PCa diagnosis using ultrasound images was relatively high, with an AUC value above 0.7. Thus, this modality is promising for PCa diagnosis that can provide instant information for further workup and help doctors decide whether to perform a prostate biopsy.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135617299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coagulation factors as potential predictors of COVID-19 patient outcomes 凝血因子作为COVID-19患者预后的潜在预测因素

Medical Journal of Indonesia Pub Date : 2023-10-20 DOI: 10.13181/mji.oa.236992

Dwi Anggita, Irawaty Djaharuddin, Harun Iskandar, Nur Ahmad Tabri, Jamaluddin Madolangan, Harry Akza Putrawan, Edward Pandu Wiriansya

{"title":"Coagulation factors as potential predictors of COVID-19 patient outcomes","authors":"Dwi Anggita, Irawaty Djaharuddin, Harun Iskandar, Nur Ahmad Tabri, Jamaluddin Madolangan, Harry Akza Putrawan, Edward Pandu Wiriansya","doi":"10.13181/mji.oa.236992","DOIUrl":"https://doi.org/10.13181/mji.oa.236992","url":null,"abstract":"BACKGROUND Causes of death and length of hospitalization in patients with COVID-19 have been associated with coagulopathy. The coagulopathy mechanism involves the process of coagulation and endothelial damage triggered by an inflammatory response of the SARS-CoV-2 infection due to excessive release of proinflammatory cytokines. This study aimed to determine the association of coagulation factors as potential predictors of COVID-19 patient outcomes. METHODS This retrospective study was performed on 595 patients at Wahidin Sudirohusodo Hospital, Makassar, from June 2020 to June 2021. Participants were recruited using total sampling and assessed for COVID-19 severity using the World Health Organization classification and coagulation factors (D-dimer, fibrinogen, thrombocyte, and prothrombin time [PT]). Patient outcome assessments were survival and length of hospitalization. RESULTS We found a significant sex-based disparity, with a higher COVID-19 incidence in males. Severe cases were more common among those aged >50 years, with prolonged hospitalization (>10 days) linked to higher severity (odds ratio [OR] = 2.22, 95% confidence interval [CI] = 1.31–3.77, p<0.001). Elevated fibrinogen and D-dimer levels, as well as prolonged PT, predicted severe cases. However, D-dimer had the highest influence compared to other coagulation factors (OR = 14.50, 95% CI = 5.85–35.95, p<0.001), while prolonged PT influenced mortality rates (OR = 4.02, 95% CI = 1.35–12.00, p = 0.01). CONCLUSIONS Coagulation factors, such as elevated D-dimer and fibrinogen levels and prolonged PT, predicted the severity of COVID-19 patients leading to death.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":"15 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135616574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quadrigeminal plate arachnoid cyst presenting with eye movement related migraine: a rare case report 以眼动相关偏头痛为表现的四叉肌板蛛网膜囊肿:罕见病例报告

Medical Journal of Indonesia Pub Date : 2023-10-20 DOI: 10.13181/mji.cr.236858

Yemima Graciela, Robert Shen, Mardjono Tjahjadi

引用次数: 0

Transventricular transforaminal endoscopic fenestration with cysto-ventriculoperitoneal shunt to manage a third ventricular arachnoid cyst: a case report 经脑室经椎间孔内窥镜开窗联合膀胱-脑室-腹膜分流术治疗第三脑室蛛网膜囊肿1例报告

Medical Journal of Indonesia Pub Date : 2023-10-17 DOI: 10.13181/mji.cr.236856

Nia Yuliatri, Ingrid Ayke Widjaya, Alphadenti Harlyjoy, Gibran Aditiara Wibawa, None Satyanegara

引用次数: 0

Risk of seizure recurrence in children with new-onset afebrile seizure 新发非热性癫痫患儿癫痫复发的风险

Medical Journal of Indonesia Pub Date : 2023-10-09 DOI: 10.13181/mji.oa.236927

Mufeed Akram Taha, Noorjan Abdullah Muhammed

{"title":"Risk of seizure recurrence in children with new-onset afebrile seizure","authors":"Mufeed Akram Taha, Noorjan Abdullah Muhammed","doi":"10.13181/mji.oa.236927","DOIUrl":"https://doi.org/10.13181/mji.oa.236927","url":null,"abstract":"BACKGROUND A seizure is a brief change in the normal neuronal electrical activity of the brain that causes changes in consciousness, perception, behavior, or movement. This study aimed to evaluate clinical findings, initial electroencephalography (EEG), and brain imaging findings as predictors of seizure recurrence after the first nonfebrile seizure. METHODS This prospective follow-up study was conducted at Azadi Teaching Hospital, Kirkuk from July 2019 to January 2022 and enrolled 150 patients, ranging from 1 month to 15 years of age, who presented with their first afebrile seizure. The seizure types were classified based on the International League Against Epilepsy in 2017. A brain imaging with EEG was performed within 72 hours after admission. RESULTS The median age of the patients was 5 years. A higher risk of seizure recurrence occurred in patients with focal seizure (relative risk [RR] = 6.604) (95% confidence interval [CI] 3.975–10.971), seizure occurrence at sleep (RR = 3.815) (95% CI 2.410–6.039), an abnormal neurological presentation such as Todd’s paralysis (RR = 1.739) (95% CI 1.252–2.415), a positive family history of seizures (RR = 2.333) (95% CI 1.598–3.408), abnormal EEG (RR = 0.171) (95% CI 0.092–0.318), and abnormal brain image findings (RR = 0.681) (95% CI 0.492–0.941) within 72 hours. Seizure recurrence was not correlated with sex. CONCLUSIONS Early and late childhood new-onset afebrile seizures with a positive family history, focal epilepsy, seizure during sleep, prolonged attack duration with frequent attacks within 24 hours, and abnormal initial EEG and brain image had a high risk of seizure recurrence.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135094821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mutation of PAX3 and MITF genes in a family with type 1 Waardenburg syndrome: a case series PAX3和& lt; em> MITF1型瓦尔登堡综合征家族基因序列分析

Medical Journal of Indonesia Pub Date : 2023-10-04 DOI: 10.13181/mji.cr.236954

Habibah Setyawati Muhiddin, Ulfah Rimayanti, Fadhlullah Latama, Andi Muhammad Ichsan, Marliyanti Nurrahmah Akib, Adelina Titirina Poli, None Budu, Andi Pratiwi

引用次数: 0

Food-induced brain activity in adult obesity: a quantitative electroencephalographic study 成人肥胖中食物引起的脑活动:定量脑电图研究

Medical Journal of Indonesia Pub Date : 2023-10-03 DOI: 10.13181/mji.oa.236974

Kemas Abdurrohim, Pradana Soewondo, Fiastuti Witjaksono, Hasan Mihardja, Wresti Indriatmi, Heri Wibowo, Selfi Handayani, Nurhadi Ibrahim

{"title":"Food-induced brain activity in adult obesity: a quantitative electroencephalographic study","authors":"Kemas Abdurrohim, Pradana Soewondo, Fiastuti Witjaksono, Hasan Mihardja, Wresti Indriatmi, Heri Wibowo, Selfi Handayani, Nurhadi Ibrahim","doi":"10.13181/mji.oa.236974","DOIUrl":"https://doi.org/10.13181/mji.oa.236974","url":null,"abstract":"BACKGROUND Obesity may be associated with declined food consumption control through neurological and behavioral processes, as well as heightened responsiveness of the brain’s reward systems. Performing neuroimaging and neurophysiological methods such as electroencephalography (EEG) can examine the connection between brain function and behavior. This study aimed to identify brain regulation of feeding behavior to food cues, which could be a potential neuromodulatory intervention target in adult obesity. METHODS This cross-sectional study was conducted at Cipto Mangunkusumo Hospital, Jakarta, involving 40 adults with obesity. EEG analysis was performed to measure electrophysiological brain activity during eyes-open condition and during exposure to high-calorie food cues. Student’s t-tests were performed to identify any significant differences between the groups (p<0.05). RESULTS Beta waves in the frontal (channel F7) and gamma waves in the central (channels C3 and C4) and parietal (channels P3 and P4) regions were significantly increased during food cues compared to resting state/eyes-open condition without stimulation. Theta waves in the frontal (channels F7 and F8), central (channel C3), and parietal (channels P3 and P4) regions and alpha waves in the central (channels C3 and C4) and parietal (channels P3 and P4) regions were significantly decreased during food cues compared with resting state. CONCLUSIONS In adults with obesity, increased beta activity in the frontal and gamma in the central and parietal regions suggested increased food-cue awareness and heightened attentional focus toward food stimuli. Additionally, decreased alpha and theta activities in frontal regions could underline deficits in executive functions and higher motivation.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135697623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic value of neutrophil-to-lymphocyte ratio and fibrinogen levels in ovarian cancer 中性粒细胞/淋巴细胞比值及纤维蛋白原水平对卵巢癌的预后价值

Medical Journal of Indonesia Pub Date : 2023-10-02 DOI: 10.13181/mji.oa.236880

Roudhona Rosaudyn, Faradillah Mutiani, Indra Yuliati, Birama Robby Indraprasta

{"title":"Prognostic value of neutrophil-to-lymphocyte ratio and fibrinogen levels in ovarian cancer","authors":"Roudhona Rosaudyn, Faradillah Mutiani, Indra Yuliati, Birama Robby Indraprasta","doi":"10.13181/mji.oa.236880","DOIUrl":"https://doi.org/10.13181/mji.oa.236880","url":null,"abstract":"BACKGROUND High neutrophil-to-lymphocyte ratio (NLR) and fibrinogen levels have been associated with mortality in several malignancies. However, the studies on the association between NLR or fibrinogen levels and ovarian cancer prognosis are inconsistent. This study aimed to investigate the prognostic roles of NLR and fibrinogen in ovarian cancer. METHODS A systematic search of electronic databases was performed to analyze studies on the association of pre-treatment NLR and fibrinogen levels with overall survival (OS) and progression-free survival (PFS) among patients with ovarian cancer. The hazard ratio (HR) and corresponding 95% confidence intervals [CIs] were analyzed. All statistical analyses were done using RevMan version 5.4 (Cochrane, United Kingdom). RESULTS A total of 7,312 patients from 27 studies were included. The median cut-off for high NLR was 3.6 for OS among 17 studies and 3.23 for PFS among 11 studies reporting an NLR HR. The median cut-off for fibrinogen levels was 4.0 in 9 studies reporting fibrinogen levels HR. High NLR was associated with lower OS (HR 1.35, 95% CI 1.18 to 1.55, p<0.0001, I2 = 76%) and PFS (HR 1.35, 95% CI 1.14 to 1.60, p = 0.0005, I2 = 71%). High fibrinogen levels were associated with lower OS (HR 1.44, 95% CI 1.14 to 1.82, p = 0.002, I2 = 81%) and PFS (HR 1.34, 95% CI 1.17 to 1.55, p<0.0001, I2 = 15%). This association occurred in all ovarian cancer types. CONCLUSIONS High pre-treatment NLR and plasma fibrinogen levels were related to poor OS and PFS in ovarian cancer.","PeriodicalId":18302,"journal":{"name":"Medical Journal of Indonesia","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135902377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0