Mass spectrometry最新文献_第3页

Determination of Choline-Containing Compounds in Rice Bran Fermented with Aspergillus oryzae Using Liquid Chromatography/Tandem Mass Spectrometry. 利用液相色谱/串联质谱法测定用黑曲霉发酵的米糠中的含胆碱化合物

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-08-08 DOI: 10.5702/massspectrometry.A0151

Masamitsu Maekawa, Anna Iwahori, Masaki Kumondai, Yu Sato, Toshihiro Sato, Nariyasu Mano

{"title":"Determination of Choline-Containing Compounds in Rice Bran Fermented with Aspergillus oryzae Using Liquid Chromatography/Tandem Mass Spectrometry.","authors":"Masamitsu Maekawa, Anna Iwahori, Masaki Kumondai, Yu Sato, Toshihiro Sato, Nariyasu Mano","doi":"10.5702/massspectrometry.A0151","DOIUrl":"10.5702/massspectrometry.A0151","url":null,"abstract":"Choline-containing compounds are essential nutrients for human activity, as they are involved in many biological processes, including cell membrane organization, methyl group donation, neurotransmission, signal transduction, lipid transport, and metabolism. These compounds are normally obtained from food. Fermented brown rice and rice bran with Aspergillus oryzae (FBRA) is a fermented food product derived from rice and rice ingredients. FBRA exhibits a multitude of functional properties with respect to the health sciences. This study has a particular focus on choline-containing compounds. We first developed a simultaneous liquid chromatography/tandem mass spectrometry (LC/MS/MS) analysis method for seven choline-containing compounds. The method was subsequently applied to FBRA and its ingredients. Hydrophilic interaction chromatography (HILIC) and selected reaction monitoring were employed for the simultaneous analysis of seven choline-containing compounds. MS ion source conditions were optimized in positive ion mode, and the product ions derived from the choline group were obtained through MS/MS optimization. Under optimized HILIC conditions, the peaks exhibited good shape without peak tailing. Calibration curves demonstrated high linearity across a 300- to 10,000-fold concentration range. The application of the method to FBRA and other ingredients revealed significant differences between food with and without fermentation. In particular, betaine and α-glycerophosphocholine were found to be highest in FBRA and brown rice malt, respectively. The results indicated that the fermentation processing of rice ingredients results in alterations to the choline-containing compounds present in foods. The developed HILIC/MS/MS method proved to be a valuable tool for elucidating the composition of choline-containing compounds in foods.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0151"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intermolecular Interactions between Aromatic Amino Acids Investigated by Ultraviolet Photodissociation Spectroscopy of Hydrogen-Bonded Clusters of Histidine and Tryptophan Enantiomers. 组氨酸和色氨酸对映体氢键簇的紫外光解光谱研究芳香氨基酸分子间相互作用。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-11-26 DOI: 10.5702/massspectrometry.A0160

Keitaro Kitahashi, Akimasa Fujihara

{"title":"Intermolecular Interactions between Aromatic Amino Acids Investigated by Ultraviolet Photodissociation Spectroscopy of Hydrogen-Bonded Clusters of Histidine and Tryptophan Enantiomers.","authors":"Keitaro Kitahashi, Akimasa Fujihara","doi":"10.5702/massspectrometry.A0160","DOIUrl":"https://doi.org/10.5702/massspectrometry.A0160","url":null,"abstract":"Intermolecular interactions between aromatic amino acids were investigated by ultraviolet photodissociation spectroscopy of hydrogen-bonded protonated clusters of histidine (His) and tryptophan (Trp) enantiomers in the gas phase. Product ion spectra and photodissociation spectra in the wavelength range of the S1-S0 transition of Trp at several temperatures (8-100 K) were obtained using a tandem mass spectrometer equipped with an electrospray ionization source and a cold ion trap. l-Trp detachment forming protonated His was the main pathway. Two bands observed at 288 and 285 nm in the photodissociation spectra of heterochiral H+(d-His)(l-Trp) indicated the coexistence of two types of conformers. The bands at 288 and 285 nm were attributed to the conformers formed from stronger and weaker intermolecular interactions, respectively. In the spectra of homochiral H+(l-His)(l-Trp), only the band due to the stronger interactions was observed at 288 nm. The intermolecular interactions of l-His with l-Trp were stronger than those of d-His with l-Trp.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0160"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11606909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study of the Deisotope Method for Mass Spectra of Complex Synthetic Polymer Mixtures Consisting of Multiple Repeating Units. 由多个重复单元组成的复杂合成聚合物混合物质谱的同位素法研究。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-12-17 DOI: 10.5702/massspectrometry.A0165

Toshiji Kudo, Shiori Yuge

引用次数: 0

Combination of Probe Electrospray Ionization Mass Spectrometry and Mass Spectrometry Imaging to Analyze Plant Alkaloids in Narcissus tazetta. 探针电喷雾电离质谱与质谱成像联合分析水仙中植物生物碱。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-12-10 DOI: 10.5702/massspectrometry.A0163

Kaoru Nakagawa, Tetsuo Iida, Manami Kobayashi, Shuichi Shimma

{"title":"Combination of Probe Electrospray Ionization Mass Spectrometry and Mass Spectrometry Imaging to Analyze Plant Alkaloids in Narcissus tazetta.","authors":"Kaoru Nakagawa, Tetsuo Iida, Manami Kobayashi, Shuichi Shimma","doi":"10.5702/massspectrometry.A0163","DOIUrl":"10.5702/massspectrometry.A0163","url":null,"abstract":"Plant alkaloids are used in a variety of medicines, such as anti-cancer drugs and analgesics. Among these plant alkaloids, galanthamine is an Amaryllidaceae type alkaloid with acetylcholinesterase inhibition activity used in the treatment of neurological diseases such as Alzheimer's disease. Although the chemical synthesis of galanthamine has been successfully achieved, Narcissus tazetta is the main source of its production. Research shows that the galanthamine content varies not only with the type of daffodil but also with the stage of development and the part of the plant. Pharmaceutical companies seek plant species with higher galanthamine content to increase pharmaceutical availability. In this study, we were able to rapidly confirm the presence of alkaloids, such as galanthamine, lycorine, and tazettine in the N. tazetta sample using the probe electrospray ionization coupled with quadrupole time-of-flight type mass spectrometry. After confirmation of the components, we then visualized the distribution of the alkaloids by mass spectrometry imaging using the atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometer. In our method, we can provide qualitative data and visualized data immediately.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0163"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparation. 大气压质谱成像使用电喷雾辅助激光解吸/电离气体通过加热管输送和最小样品制备。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-12-29 DOI: 10.5702/massspectrometry.A0167

Riku Hirotani, Yuto Miyoshi, Varun Sendilraj, Hisanao Hazama

{"title":"Atmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparation.","authors":"Riku Hirotani, Yuto Miyoshi, Varun Sendilraj, Hisanao Hazama","doi":"10.5702/massspectrometry.A0167","DOIUrl":"https://doi.org/10.5702/massspectrometry.A0167","url":null,"abstract":"Mass spectrometry (MS) is a valuable tool that enables label-free analysis and the ability to measure multiple molecules. The atmospheric pressure MS imaging (MSI) method usually requires tedious sample preparation. A simple ionization method with minimal sample preparation is needed for high-throughput analysis. We have developed an ion source that does not require sample preparation such as thinning, curing, planarization, or addition of matrix by the electrospray-assisted laser desorption/ionization with gas transportation (ELDI-GT). The sample is transported with nitrogen gas through a heated tube to the electrospray. The ion signal of protonated caffeine was measured under different transport conditions. The ion signal intensity was found to increase 11-fold by changing the flow rate and tube temperature from 2.8 cm3/s and 473 K to 25 cm3/s and 673 K. ELDI-GT was able to visualize the localization of caffeine crystals at a pixel size of 50 µm using MSI because of the effective GT using the heated tube. The dependence of the ion signal intensity was discussed on the amount of heat applied to the sample in the heated tube. ELDI-GT allowed accurate localization of caffeine at a pixel size of 50 µm without the need to apply thinning and matrix to a sample.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0167"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11703791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the Surface Morphology of a Metal Film on Ion Yields in a Platinum-Film Surface-Assisted Laser Desorption/Ionization Mass Spectrometry. 金属膜表面形态对铂膜表面辅助激光解吸/电离质谱仪离子产量的影响

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-11-12 DOI: 10.5702/massspectrometry.A0154

Kotaro Hashimoto, Kyosuke Kaneda, Taichi Shimazaki, Chouma Kurihashi, Shuhei Yamamoto, Riko Takata, Shota Nakanishi, Issey Osaka

{"title":"Effect of the Surface Morphology of a Metal Film on Ion Yields in a Platinum-Film Surface-Assisted Laser Desorption/Ionization Mass Spectrometry.","authors":"Kotaro Hashimoto, Kyosuke Kaneda, Taichi Shimazaki, Chouma Kurihashi, Shuhei Yamamoto, Riko Takata, Shota Nakanishi, Issey Osaka","doi":"10.5702/massspectrometry.A0154","DOIUrl":"10.5702/massspectrometry.A0154","url":null,"abstract":"Matrix-assisted laser desorption ionization (MALDI) and surface-assisted laser desorption ionization (SALDI) mass spectrometry (MS), which can detect biomolecules and polymers, are widely used in biochemistry and material science. Some compounds that are difficult to ionize using MALDI can be ionized using SALDI. However, it is difficult to obtain high ion yields using SALDI/MS. In this study, a fabricated platinum (Pt) film with nanostructures on the sample surface using a sputtering method was evaluated to determine the optimal metal film for ion yield in SALDI. The surface morphology of the Pt film was analyzed using scanning electron microscopy (SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM), X-ray reflectivity (XRR), and ultraviolet-visible-near-infrared (UV-Vis-NIR) reflectance spectroscopy. The SEM, AFM, and TEM images of the Pt film showed the deposited metal film giving high ion yields of polyethylene glycol (PEG) in SALDI/MS with a Pt film (Pt-SALDI) that had a rough surface. The densities and reflectivity of films were analyzed by XRR and UV-Vis-NIR. The higher ion yields of PEG were obtained by Pt-SALDI with the Pt films with lower densities and reflectivity. This indicates that the deposition conditions for the Pt films significantly improved the ion yield in Pt-SALDI/MS. The Pt-SALDI has ionization capabilities different from those of MALDI. Therefore, optimization of Pt film for SALDI/MS and the MS imaging allows more compounds to be detected with higher sensitivity.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0154"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the Correlation between Cholesterol Levels in Blood Using Clinical Data and Hair Using Mass Spectrometry Imaging. 利用临床数据分析血液中胆固醇水平与利用质谱成像分析头发中胆固醇水平之间的相关性。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-07-24 DOI: 10.5702/massspectrometry.A0149

Erika Nagano, Hiromi Saito, Tetsuya Mannari, Munekazu Kuge, Kazuki Odake, Shuichi Shimma

{"title":"Analysis of the Correlation between Cholesterol Levels in Blood Using Clinical Data and Hair Using Mass Spectrometry Imaging.","authors":"Erika Nagano, Hiromi Saito, Tetsuya Mannari, Munekazu Kuge, Kazuki Odake, Shuichi Shimma","doi":"10.5702/massspectrometry.A0149","DOIUrl":"10.5702/massspectrometry.A0149","url":null,"abstract":"Mass spectrometry imaging (MSI) is a technique that visualizes the distribution of molecules by ionizing the components on the surface of a sample and directly detecting them. Previously, MSI using hair has primarily been used in the forensic field to detect illegal drugs. On the other hand, there are few examples of using this technology for health monitoring. In this study, hair and clinical data were collected from 24 subjects, and the correlation between blood cholesterol levels and cholesterol detected from cross-sectional hair slices was analyzed. As a result, a positive correlation with a correlation coefficient of 0.43 was observed between blood cholesterol and cholesterol detected from hair. Furthermore, when comparing the results of fluorescence staining (FS) of hair cholesterol with Filipin III and the MSI results, it was found that while FS could visualize detailed hair structures, there were cases where the results differed from MSI, possibly due to some cholesterol loss during the staining process. In the future, if various disease biomarkers can be detected using hair MSI, it could potentially become a non-invasive diagnostic method.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0149"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141794503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ambient Mass Spectrometry and Machine Learning-Based Diagnosis System for Acute Coronary Syndrome. 基于环境质谱和机器学习的急性冠状动脉综合征诊断系统。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-07-11 DOI: 10.5702/massspectrometry.A0147

Que N N Tran, Takeshi Moriguchi, Masateru Ueno, Tomohiko Iwano, Kentaro Yoshimura

{"title":"Ambient Mass Spectrometry and Machine Learning-Based Diagnosis System for Acute Coronary Syndrome.","authors":"Que N N Tran, Takeshi Moriguchi, Masateru Ueno, Tomohiko Iwano, Kentaro Yoshimura","doi":"10.5702/massspectrometry.A0147","DOIUrl":"10.5702/massspectrometry.A0147","url":null,"abstract":"Aims: The purpose of this study is to establish a novel diagnosis system in early acute coronary syndrome (ACS) using probe electrospray ionization-mass spectrometry (PESI-MS) and machine learning (ML) and to validate the diagnostic accuracy. Methods: A total of 32 serum samples derived from 16 ACS patients and 16 control patients were analyzed by PESI-MS. The acquired mass spectrum dataset was subsequently analyzed by partial least squares (PLS) regression to find the relationship between the two groups. A support vector machine, an ML method, was applied to the dataset to construct the diagnostic algorithm. Results: Control and ACS groups were separated into the two clusters in the PLS plot, indicating ACS patients differed from the control in the profile of serum composition obtained by PESI-MS. The sensitivity, specificity, and accuracy of our diagnostic system were all 93.8%, and the area under the receiver operating characteristic curve showed 0.965 (95% CI: 0.84-1). Conclusion: The PESI-MS and ML-based diagnosis system are likely an optimal solution to assist physicians in ACS diagnosis with its remarkably predictive accuracy.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0147"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Mass Spectrometry Imaging Method to Evaluate the Penetration of Moisturizing Components Coated on Surgical Gloves into Artificial Membranes. 开发一种质谱成像方法，用于评估涂在手术手套上的保湿成分对人造膜的渗透。

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-03-26 DOI: 10.5702/massspectrometry.A0145

Erika Nagano, Kazuki Odake, Toru Akiyoshi, Shuichi Shimma

{"title":"Development of a Mass Spectrometry Imaging Method to Evaluate the Penetration of Moisturizing Components Coated on Surgical Gloves into Artificial Membranes.","authors":"Erika Nagano, Kazuki Odake, Toru Akiyoshi, Shuichi Shimma","doi":"10.5702/massspectrometry.A0145","DOIUrl":"10.5702/massspectrometry.A0145","url":null,"abstract":"Skin dryness and irritant contact dermatitis induced by the prolonged use of surgical gloves are issues faced by physicians. To address these concerns, manufacturers have introduced surgical gloves that incorporate a moisturizing component on their inner surface, resulting in documented results showing a reduction in hand dermatitis. However, the spatial distribution of moisturizers applied to surgical gloves within the integument remains unclear. Using matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI), we investigated the spatial distribution of moisturizers in surgical gloves within artificial membranes. Recently, dermal permeation assessments using three-dimensional models, silicone membranes, and Strat-M have gained attention as alternative approaches to animal testing. Therefore, in this study, we established an in vitro dermal permeation assessment of commercially available moisturizers in surgical gloves using artificial membranes. In this study, we offer a methodology to visualize the infiltration of moisturizers applied to surgical gloves into an artificial membrane using MALDI-MSI, while evaluating commercially available moisturizer-coated surgical gloves. Using our penetration evaluation method, we confirmed the infiltration of the moisturizers into the polyethersulfone 2 and polyolefin layers, which correspond to the epidermis and dermis of the skin, after the use of surgical gloves. The MSI-based method presented herein demonstrated the efficacy of evaluating the permeation of samples containing active ingredients.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0145"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Desorption of Positive and Negative Ions from Areoles of Opuntia microdasys Cactus at Atmospheric Pressure: Cactus-MS. 在大气压力下从 Opuntia microdasys 仙人掌小窠中解吸正离子和负离子：Cactus-MS.

Mass spectrometry Pub Date : 2024-01-01 Epub Date: 2024-06-12 DOI: 10.5702/massspectrometry.A0146

Jürgen H Gross

{"title":"Desorption of Positive and Negative Ions from Areoles of Opuntia microdasys Cactus at Atmospheric Pressure: Cactus-MS.","authors":"Jürgen H Gross","doi":"10.5702/massspectrometry.A0146","DOIUrl":"10.5702/massspectrometry.A0146","url":null,"abstract":"The areoles and spines of cacti can be used to desorb ions of ionic liquids (ILs) by the mere action of an electric field into the atmospheric pressure (AP) interface of a mass spectrometer. The small cactus species Opuntia microdasys bears numerous very fine hairs on its areoles and tiny sharp spines that appeared suited to serve as needle electrodes sharp enough for field desorption of ions to occur. In fact, positive and negative ions of four ILs could be desorbed by a process analogous to AP field desorption (APFD). In contrast to APFD where activated field emitters are employed, the ILs were deposited onto one or two adjacent areoles by applying 1-3 µL of a dilute solution in methanol. After evaporation of the solvent, the cactus was positioned next to the spray shield electrode of a trapped ion mobility-quadrupole-time-of-flight instrument. Desorption of IL cations and IL anions, respectively, did occur as soon as the electrode was set to potentials in the order of ±4.5 kV, while the cactus at ground potential was manually positioned in front of the entrance electrode to bring the areole covered with a film of the sample into the right position. Neither did mixing of ILs occur between neighboring areoles nor did the cactus suffer any damage upon its use as a botanical field emitter.","PeriodicalId":18243,"journal":{"name":"Mass spectrometry","volume":"13 1","pages":"A0146"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141419783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0