LGBT health最新文献

{"title":"Prevalence of Hypermobile Ehlers-Danlos Syndrome in Transgender and Gender Diverse Individuals: A Retrospective Cohort Study.","authors":"Tomasz Tabernacki, Lydia McLachlan, Matthew Loria, Shubham Gupta, Swagata Banik, Kirtishri Mishra, Megan McNamara","doi":"10.1177/23258292251382250","DOIUrl":"https://doi.org/10.1177/23258292251382250","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> This study compared the prevalence of hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorder (HSD) between transgender and gender-diverse (TGD) individuals and cisgender individuals. <b><i>Methods:</i></b> We conducted a retrospective analysis using a large electronic health record database spanning 2004-2024. TGD individuals were identified using International Classification of Diseases, Tenth Revision codes related to gender identity and stratified by hormone therapy status. Cisgender comparison groups were defined by the absence of gender identity diagnoses and hormone therapy exposure. Prevalence odds ratios (ORs) with 95% confidence intervals were calculated to compare hEDS and HSD diagnoses between groups. <b><i>Results:</i></b> TGD individuals demonstrated a significantly higher prevalence of hEDS and HSD than cisgender individuals (OR: 18.45). The prevalence among TGD individuals assigned female at birth was 2.62%, and among those assigned male at birth, 1.00%, compared with 0.16% and 0.04% in cisgender females and males, respectively. Hormone therapy status was not associated with significant differences in prevalence. <b><i>Conclusions:</i></b> These findings indicate a substantially increased burden of hypermobility-related disorders among TGD individuals. Enhanced clinical recognition and multidisciplinary management strategies are needed to address the unique health care challenges faced by this population.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Well-Woman Visits and Cervical Cancer Screening at the Intersection of Sexual Orientation and Race/Ethnicity Among Illinois Women.","authors":"Caitlin M Meyer, Kristin Rankin, Arden Handler, William Barshop, Madison Levecke, Brenikki Floyd","doi":"10.1177/23258292251379503","DOIUrl":"https://doi.org/10.1177/23258292251379503","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> This study examined receipt of a well-woman visit (WWV) and cervical cancer screening (CCS) at the intersection of sexual orientation and race/ethnicity among Illinois women aged 21-65. <b><i>Methods:</i></b> This study used 2016, 2018, and 2020 Illinois Behavioral Risk Factor Surveillance System (BRFSS) data for women aged 21-65 to examine rates of CCS (<i>n</i> = 2848) and 2016-2018, 2020, and 2021 Illinois BRFSS data to examine WWV receipt (<i>n</i> = 5863) by sexual orientation (heterosexual vs. lesbian, gay, and bisexual [LGB]). Self-reported race/ethnicity was tested as an effect modifier to assess intersectionality. Using binomial regression, adjusted prevalence differences (aPD) and 95% confidence intervals (CIs) were estimated. Covariates included age, education, marital status, employment, and health insurance coverage. <b><i>Results:</i></b> Overall, 4.6% of Illinois women aged 21-65 self-identified as LGB. Heterosexual and LGB women had a similar prevalence of receipt of both a WWV (77.1% and 71.7%, respectively; aPD = 3.22, 95% CI: -3.62 to 10.06) and CCS (85.3% and 83.4%, respectively; aPD = 2.13, 95% CI: -4.77 to 9.04). Among non-Hispanic (NH) Black women, heterosexual compared with LGB women had a higher prevalence of receiving both types of care; however, adjusted associations included the null. Hispanic women had similar prevalence estimates by sexual orientation for both outcomes, and NH White heterosexual compared with LGB women had a higher prevalence of CCS, but not WWV. <b><i>Conclusion:</i></b> In Illinois overall, heterosexual and LGB women received preventive care at similar rates. However, when stratified by race/ethnicity, WWV and CCS receipt rates may be higher for heterosexual compared with LGB women, indicating potential missed opportunities for preventive care.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Childhood Experiences and Mental Health Outcomes Among Sexual Minority Women: A Population-Based Study.","authors":"Fenfen Ge, Arna Hauksdóttir, Huan Song, Donghao Lu, Gunnar Tómasson, Harpa Rúnarsdóttir, Marín Dögg Bjarnadóttir, Jóhanna Jakobsdóttir, Fang Fang, Thor Aspelund, Unnur Anna Valdimarsdóttir, Edda Bjork Thordardottir","doi":"10.1177/23258292251376565","DOIUrl":"https://doi.org/10.1177/23258292251376565","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> We aimed to investigate the association between sexual orientation and multiple types of adverse childhood experiences (ACEs) and to what extent ACEs mediate the association between sexual orientation and symptoms of depression and anxiety among sexual minority women (SMW). <b><i>Methods:</i></b> This was a cross-sectional analysis nested within the nationally representative Icelandic Stress-And-Gene-Analysis cohort. Data were collected from March 2018 to June 2019. Participants included 11,007 women, aged 18-69, with data on sexual orientation and ACEs. Self-reported data were obtained on 13 different ACEs, and current symptoms of depression and anxiety. <b><i>Results:</i></b> Overall, 724 (6.6%) identified as sexual minority. The mean age of SMW was 34.0 years (standard deviation [SD] 14.0) and 44.7 years (SD 14.0) for heterosexual women. SMW were more likely to report six or more ACEs than heterosexual women (21.7% vs. 11.3%, respectively), yielding an adjusted odds ratio (aOR) of 2.26 (95% confidence interval [CI] 1.76-2.91). SMW were more likely than heterosexual women to report four types of ACEs: specifically bullying, emotional abuse, sexual abuse, and mental illness in the household (aOR ranging from 1.36 to 1.71). SMW reported higher odds of current symptoms of depression (aOR = 2.10, 95% CI 1.77-2.49) and anxiety (aOR = 1.69, 95% CI 1.41-2.02). The total number of ACEs mediated 32.6% of the association between sexual orientation and depression, and 43.2% of the association between sexual orientation and anxiety. <b><i>Conclusion:</i></b> These findings suggest that ACEs are a major contributor to the mental health disparities observed among SMW.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the Influence of Sexual Orientation-Related Nondiscrimination Laws on 30-Year Cardiovascular Disease Risk.","authors":"Yashika Sharma, Morgan Philbin, Bethany Everett, Caleigh Dwyer, Anisha Bhargava, Danny Doan, Lauren B Beach, Lisa Pardee, Billy A Caceres","doi":"10.1089/LGBT.2024.0268","DOIUrl":"10.1089/LGBT.2024.0268","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> Our aim was to expand existing evidence on structural determinants of cardiovascular health disparities among lesbian, gay, and bisexual (LGB) adults by examining sexual orientation differences in the impact of sexual orientation-related nondiscrimination laws on 30-year cardiovascular disease (CVD) risk. <b><i>Methods:</i></b> We analyzed data from Waves III (2001-2002), IV (2008-2009), and V (2016-2018) of the National Longitudinal Study of Adolescent to Adult Health. Sexual orientation was categorized as exclusively heterosexual, mostly heterosexual, bisexual, or gay/lesbian. We categorized changes in sexual orientation-related nondiscrimination laws between Waves III-IV as no change (reference group), increased, or decreased. We assessed 30-year CVD risk at Wave V using the Framingham Risk Score. We ran sex-stratified regression models to examine whether the association between changes in sexual orientation-related nondiscrimination laws and 30-year CVD risk was moderated by sexual orientation. <b><i>Results:</i></b> The sample included 3768 participants (mean age [standard deviation] = 28.7 [±1.72] years) of whom approximately 77% were White, 11% Hispanic, and 51% female. Compared with exclusively heterosexual participants, an increase in nondiscrimination laws was associated with lower CVD risk among mostly heterosexual women (<i>B =</i> -5.05, 95% confidence interval [CI] = -8.50 to -1.59) and gay men (<i>B =</i> -10.22, 95% CI = -19.05 to -1.39). There were no significant differences for other LGB subgroups when compared with exclusively heterosexual adults. <b><i>Conclusions:</i></b> Increasing laws that prohibit sexual orientation-related discrimination may play an important role in reducing CVD risk among some LGB subgroups. These findings can inform structural-level interventions to reduce CVD risk among LGB adults.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Sexual Orientation and the Impact, Diagnosis, and Treatment of Endometriosis.","authors":"Shea E O'Donnell, Linda Abarbanell","doi":"10.1177/23258292251374717","DOIUrl":"https://doi.org/10.1177/23258292251374717","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> This study examined the association between sexual orientation and the impact, diagnosis, and treatment of endometriosis. <b><i>Methods:</i></b> An online survey was conducted in 2023 with 150 adults in the United States diagnosed with endometriosis, 119 of whom identified as heterosexual and 31 with a minority sexual orientation. The impact of endometriosis was measured using the Endometriosis Impact Questionnaire (EIQ), consisting of eight subscales. We also assessed factors related to diagnosis and treatment satisfaction. Data were analyzed using independent samples <i>t</i>-tests and multiple linear regression. <b><i>Results:</i></b> Participants with a minority sexual orientation had a higher average impact of endometriosis on the EIQ physical, psychological, and social subscales than heterosexual participants but a lower impact on the fertility subscale, all with medium effect sizes. They took an average of 5 years longer to be diagnosed, with 83.9% of sexual minority versus 45.4% of heterosexual participants receiving at least one misdiagnosis. More sexual minority versus heterosexual participants also reported feeling dismissed or disbelieved (96.8% vs. 64.4%), not feeling listened to by providers (96.8% vs. 62.2%), and having difficulty communicating with providers (90.3% vs. 55.5%). The association between sexual orientation and the EIQ physical, psychological, and social subscales could be explained, in particular, by having been misdiagnosed. <b><i>Conclusions:</i></b> These results highlight the need for better medical education and inclusive gynecological care to promote timely diagnosis and treatment of endometriosis. They also suggest that provider biases and discrimination may contribute to a greater impact of endometriosis on sexual minority patients.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Letter:</i> Gender Dysphoria and Transition in a Patient with Kallmann Syndrome: A Case Report.","authors":"Emilia Doda-Nowak, Anna Cykowska, Remigiusz Domin, Marek Ruchała, Katarzyna Ziemnicka","doi":"10.1177/23258292251378150","DOIUrl":"https://doi.org/10.1177/23258292251378150","url":null,"abstract":"","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protecting What We Built: A Reflection on Sexual and Gender Minority Research Achievements, What We Stand to Lose, and How to Sustain the Work Ahead.","authors":"Katrina S Kennedy, Harry Barbee, Danielle German","doi":"10.1177/23258292251376566","DOIUrl":"https://doi.org/10.1177/23258292251376566","url":null,"abstract":"<p><p>Amid increasing political threats to sexual and gender minority (SGM) research, this perspective reflects on the evolution of SGM research from the margins of public health to a robust field and assesses the unique vulnerabilities facing SGM researchers across career stages. We discuss how the field can protect its infrastructure, sustain its workforce, and preserve its impact, drawing inspiration from the harm reduction movement and our individual and collective experiences. This is both a reflection and a call to action grounded in care, intergenerational knowledge and solidarity, and the refusal to be erased.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Self-Reassurance in the Relation Between Internalized Gender Stigma, Self-Criticism, and Depression Among Transgender and Nonbinary Patients.","authors":"Roberto Baiocco, Fulvio Gregori, Fau Rosati, Nicola Petrocchi, Jessica Pistella","doi":"10.1177/23258292251371064","DOIUrl":"https://doi.org/10.1177/23258292251371064","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> This cross-sectional study investigated self-reassurance as a protective factor in mitigating depression related to internalized gender stigma and enhancing overall well-being among transgender and nonbinary (TNB) individuals during the first step of the gender-affirmation process. <b><i>Methods:</i></b> The study included 101 TNB individuals (mean age = 26.42, standard deviation = 8.83) accessing the \"Be as You Are\" Clinical and Research Center at Sapienza University of Rome, Italy, which offers psychological support for individuals undergoing gender-affirmation processes, from 2021 to 2024. Participants completed the Gender Minority Stress and Resilience Scale to assess internalized gender stigma; the Self-Criticizing/Attacking and Self-Reassuring Scale to evaluate self-criticism (i.e., hated-self and inadequate-self), and self-reassurance; and the Symptom Checklist-90 to measure depressive symptoms. Mediation and moderated mediation models were tested. <b><i>Results:</i></b> Mediation models indicated that inadequate-self significantly mediated the relationship between internalized gender stigma and depressive symptoms. The moderated mediation analysis revealed a complex pattern: higher levels of self-reassurance were associated with a more pronounced mediating effect of inadequate-self, suggesting that self-reassurance may facilitate awareness and processing of self-critical thoughts rather than simply buffer their impact. These findings suggest that self-reassurance is a complex psychological resource that may facilitate recognizing self-critical processes and contribute to emotional regulation during the gender-affirming process. <b><i>Conclusion:</i></b> These results underscore the dynamic role of self-reassurance in the initial stages of the gender-affirming process. Clinical approaches such as compassion-focused therapy may help foster self-reassurance and alleviate the psychological burden of minority stress, particularly during the vulnerable period of accessing gender-affirming care.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Self-Reported Sexual Orientation Fluidity with Health and Behavior of Adults: Analysis of the Research Program on Genes, Environment, and Health Cohort.","authors":"Adovich S Rivera, Chun R Chao, Rulin C Hechter","doi":"10.1177/23258292251364913","DOIUrl":"https://doi.org/10.1177/23258292251364913","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> Health disparities by sexual orientation fluidity are relatively unexplored in middle or late adulthood. We assessed differences in self-reported health and health behaviors according to fluidity status. <b><i>Methods:</i></b> We analyzed baseline (2002-2010) and follow-up (2015-2023) survey data of Research Program on Genes, Environment, and Health participants. We classified people based on responses to sexual orientation questions: consistently heterosexual, consistently sexual minority, and fluid (changed reported orientation). We then compared health behavior (smoking, binge drinking, and physical activity) and self-rated health (Patient-Reported Outcomes Measurement Information System and EuroQol EQ-5D-3L) across groups using linear or logistic regression with or without weights for attrition using complete case data and after multiple imputation. <b><i>Results:</i></b> Of the 32,058 adults (mean age: 56 years, male: 39.6%), 378 (1.2%) were fluid. Compared with consistently heterosexual adults, fluid individuals had significantly worse self-rated health scores after adjustment for demographics and attrition, although most differences were not clinically meaningful. No differences in health behavior were noted in adjusted analyses. <b><i>Conclusion:</i></b> Sexual orientation fluidity occurs in older adults, and this group may have worse health than their heterosexual counterparts.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of and Recommendations for Asynchronous Online Focus Group Methodology for Sexual and Reproductive Health Research with Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, Asexual, and Other Sexuality- and Gender-Expansive People with a Cervix.","authors":"Madeline C Montgomery, Melissa A Clark, Don Operario, Madina Agénor","doi":"10.1177/23258292251367454","DOIUrl":"https://doi.org/10.1177/23258292251367454","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> This study aimed to characterize benefits of asynchronous online focus groups (AOFGs) for lesbian, gay, bisexual, transgender, queer, intersex, asexual, and other sexuality- and gender-expansive (LGBTQIA+) young adults with a cervix and to identify strategies for maximizing those benefits and optimizing data collection in order to increase equitable representation of this population in health research. <b><i>Methods:</i></b> From March to September 2022, we conducted six gender-stratified AOFGs with cisgender women, nonbinary people, and transgender men with a cervix ages 21-29 living in Massachusetts and Rhode Island. Participants completed a questionnaire to evaluate AOFG procedures and experiences. Based on these data and our observations of AOFG engagement, we developed and evaluated strategies to optimize both data collection and participant benefit. <b><i>Results:</i></b> AOFGs provided participants with informational and instrumental support, connection through shared experiences, and opportunity for introspection. Participants expressed a strong desire for social interaction within AOFG discussions, and we identified several strategies that were effective in promoting engagement and interaction in AOFGs. <b><i>Conclusion:</i></b> AOFGs can facilitate inclusion in research of LGBTQIA+ individuals for whom other data collection methods are inaccessible, and may offer direct social and emotional benefits to participants. Promoting social interaction among participants is essential for optimizing these benefits. These findings offer important insight for AOFG methodology as a means of increasing equitable representation of LGBTQIA+ people in health research while offering direct and immediate benefits to participants.</p>","PeriodicalId":18062,"journal":{"name":"LGBT health","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}