Rasim Khalilov, Steffen Seyfried, Christoph Reissfelder, Julia Hardt, Florian Herrle, Vugar Yagublu
{"title":"Impact of anastomotic leakage and radiotherapy on long-term quality of life after sphincter-saving rectal resections.","authors":"Rasim Khalilov, Steffen Seyfried, Christoph Reissfelder, Julia Hardt, Florian Herrle, Vugar Yagublu","doi":"10.1007/s00423-025-03799-1","DOIUrl":"10.1007/s00423-025-03799-1","url":null,"abstract":"<p><strong>Background: </strong>The impact of anastomotic leakage (AL) on quality of life (QoL) following low anterior resections (LAR) remains a pressing concern, particularly as advancements in surgical techniques and multimodal treatments have resulted in an increasing number of survivors.</p><p><strong>Methods: </strong>This study evaluated how AL affected health-related QoL in patients treated at the Department of Surgery, University hospital Mannheim of Heidelberg University from 2010 to 2021, utilizing the LARS score, the EORTC QLQ-C30, and the EORTC QLQ-CR29 questionnaires.</p><p><strong>Results: </strong>The study included 20 patients in each group, with those having AL matched 1:1 to control subjects without AL, based on criteria such as age, gender, comorbidities, tumor location, and resection degree. Both groups showed impaired QoL in EORTC assessments, with no statistically significant differences except in the abdominal pain scale of EORTC QLQ-CR29, which was higher for AL patients (19.99 ± 22.68 vs. 6.66 ± 17.43; p = 0.03). Comparison of QoL between patients who received neoadjuvant radiotherapy and those who did not, independent of AL, revealed significantly reduced QoL in several scales of both the EORTC QLQ-C30 and QLQ-CR29 assessments. A statistically significant worsening of QoL was observed in the sore skin domain (36.66±34.81 for RT vs. 3.70±11.11 without RT; p = 0.02) of the EORTC QLQ-CR29 among AL patients who received neoadjuvant radiotherapy. AL patients treated with Endoscopic Vacuum Therapy (EVT) showed improved QoL.</p><p><strong>Conclusions: </strong>AL alone does not appear to be an independent risk factor for impaired QoL after LAR for rectal cancer. However, the combined effect of AL and neoadjuvant radiotherapy may contribute to worse functional outcomes, significantly impacting QoL. Effective AL management with EVT can help mitigate these effects and improve patient outcomes.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"222"},"PeriodicalIF":2.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Feng-Ching Tsai, Yih Jong Chern, Yu-Jen Hsu, Chun-Kai Liao, Ching-Chung Cheng, Wen-Sy Tsai, Pao-Shiu Hsieh, Jeng-Fu You
{"title":"Comparative outcomes of intracorporeal and extracorporeal anastomosis following laparoscopic colectomy in patients with obesity with Colon cancer.","authors":"Feng-Ching Tsai, Yih Jong Chern, Yu-Jen Hsu, Chun-Kai Liao, Ching-Chung Cheng, Wen-Sy Tsai, Pao-Shiu Hsieh, Jeng-Fu You","doi":"10.1007/s00423-025-03805-6","DOIUrl":"10.1007/s00423-025-03805-6","url":null,"abstract":"","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"221"},"PeriodicalIF":2.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term outcomes of S-1 monotherapy in stage IIIA gastric cancer with small tumors and low nodal involvement.","authors":"Tsunehiko Maruyama, Yoshimasa Akashi, Reiji Nozaki, Yusuke Ozawa, Makoto Uchino, Tatsuya Oda","doi":"10.1007/s00423-025-03781-x","DOIUrl":"10.1007/s00423-025-03781-x","url":null,"abstract":"<p><strong>Background: </strong>In Japan, adjuvant chemotherapy with docetaxel/S-1 is recommended for stage III gastric cancer. However, this regimen may not be suitable for all patients due to toxicity and tolerability issues, particularly in older individuals or those with comorbidities. This study aimed to explore prognostic factors in stage IIIA gastric cancer and assess long-term outcomes in patients treated with S-1 monotherapy after curative gastrectomy.</p><p><strong>Methods: </strong>We retrospectively analyzed 73 patients with stage IIIA gastric cancer (UICC 7th edition) who underwent curative gastrectomy and received postoperative adjuvant S-1 monotherapy between 2005 and 2018.Various prognostic factors, including preoperative (age, sex, BMI, tumor markers), perioperative (surgical approach, operative duration, blood loss, complications), and tumor-related variables (tumor size, lymph node status, histological features), were analyzed. Recurrence-free survival (RFS) was the primary endpoint, and cut-off values were determined using ROC analysis. Cox proportional hazards models were used for univariate and multivariate analyses.</p><p><strong>Results: </strong>The 3- and 5-year RFS rates were 71.7% and 64.3%, respectively. Multivariate analysis identified smaller tumor size (≤ 55.0 mm, P = 0.006) and lower lymph node positivity rate (≤ 0.079, P = 0.008) as independent favorable prognostic factors.</p><p><strong>Conclusion: </strong>S-1 monotherapy may be associated with favorable long-term outcomes in selected patients with stage IIIA gastric cancer who have small tumors and low lymph node positivity rates. While these results are encouraging, they should not be interpreted as a rationale for broadly recommending S-1 monotherapy. Further studies are needed to define its role in individualized treatment strategies.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"219"},"PeriodicalIF":2.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henning Wendelin Wolf, Sara Canovi, Christian Andreas Nebiker
{"title":"Do stricter criteria for intraoperative parathyroid hormone monitoring reduce the risk of persistence or reoperation in primary hyperparathyroidism? A receiver operating characteristic analysis.","authors":"Henning Wendelin Wolf, Sara Canovi, Christian Andreas Nebiker","doi":"10.1007/s00423-025-03796-4","DOIUrl":"10.1007/s00423-025-03796-4","url":null,"abstract":"<p><strong>Purpose: </strong>Intraoperative parathyroid hormone (PTH) measurement is a beneficial tool in the surgical management of primary hyperparathyroidism. The expected degree of intraoperative PTH reduction, which guides surgical decision-making, determines the sensitivity and specificity of this test. While stricter criteria may enhance diagnostic accuracy, an optimal threshold has not been conclusively established. The aim of this study was to identify the PTH reduction threshold that provides the highest sensitivity and specificity for achieving biochemical cure.</p><p><strong>Patients and methods: </strong>A retrospective analysis was conducted on 141 patients who underwent parathyroidectomy for primary hyperparathyroidism, focusing on the intraoperative drop in PTH and surgical success. A receiver operating characteristic analysis was performed to identify the optimal threshold that balances sensitivity and specificity in predicting biochemical cure.</p><p><strong>Results: </strong>The mean percentage reduction at the end of surgery was 73.93% (SD ± 16.54%) with an overall cure rate of 94%. The area under the curve was 0.73 for a 50% PTH reduction, 0.77 for a 60% reduction, and 0.68 for a 70% reduction.</p><p><strong>Conclusion: </strong>The optimal balance between sensitivity and specificity was achieved with a 60% intraoperative PTH reduction. Stricter criteria increase sensitivity but may also raise the risk of surgical overtreatment.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"220"},"PeriodicalIF":2.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk assessment of gallbladder cancer in patients with primary sclerosing cholangitis and gallbladder polyps: a systematic review.","authors":"Ieva Grikyte, Povilas Ignatavicius","doi":"10.1007/s00423-025-03678-9","DOIUrl":"10.1007/s00423-025-03678-9","url":null,"abstract":"<p><strong>Purpose: </strong>To review, evaluate and summarize data from the literature presenting the risk of developing gallbladder cancer in patients with PSC and gallbladder polyps.</p><p><strong>Methods: </strong>The systematic review was performed according to PRISMA recommendations and registered in the PROSPERO database. The PubMed, ScienceDirect, Web of Science, Biomed Central and EBSCOhost databases were used. Studies analysing patients with PSC and gallbladder polyps, their association with malignancy and outcomes were included.</p><p><strong>Results: </strong>Five retrospective studies and one case-control study with a total of 3415 patients diagnosed with PSC were included. Radiological examination of these 3324 patients with PSC revealed 207 (6.2%) gallbladder polyps, of which 34 (16.4%) were identified as gallbladder mass lesions. Of available histology results, 116 (34%) had gallbladder polyps. Out of these 116 patients with gallbladder polyps, gallbladder carcinoma (GBC) was found in 48 (41.4%) patients. The mean size of gallbladder polyps with adenocarcinoma ranged from 2.1 cm to 2.4 cm, whereas benign polyps ranged from 0.6 cm to 1.5 cm.</p><p><strong>Conclusion: </strong>Gallbladder polyps with malignant changes are often observed in patients diagnosed with PSC. This supports international recommendations that cholecystectomy should be performed regardless of gallbladder polyp's size in PSC patients.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"216"},"PeriodicalIF":2.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ludger Staib, Frank Willeke, Dietmar Stephan, Vivianda Menke, Olaf Hansen, Narimantas Evaldas Samalavicius, Vaida Nausediene, Burghard Abendstein, Tomislav Kulis, Christian Jackisch, Michael Lein, Johannes Schmidt, Friedemann Horst, Mareike Kristina Möller
{"title":"Safety with the senhance™ robotic system in 3,239 patients across various surgical disciplines.","authors":"Ludger Staib, Frank Willeke, Dietmar Stephan, Vivianda Menke, Olaf Hansen, Narimantas Evaldas Samalavicius, Vaida Nausediene, Burghard Abendstein, Tomislav Kulis, Christian Jackisch, Michael Lein, Johannes Schmidt, Friedemann Horst, Mareike Kristina Möller","doi":"10.1007/s00423-025-03772-y","DOIUrl":"10.1007/s00423-025-03772-y","url":null,"abstract":"<p><strong>Purpose: </strong>At present, robotic surgery has found its most frequent application in gastrointestinal, gynaecological, and urological procedures, presenting a seamless integration of advanced technology. The Senhance™ Robotic System certainly contributes to this evolution, gracefully employed to enhance precision and efficacy in these surgical disciplines. However, safety data, such as conversion rates, robotic malfunctions, and adverse event rates, are still lacking on a large scale.</p><p><strong>Methods: </strong>To shed light on this, data from nine European centres (N = 3,239) was collected prospectively as part of the TRUST registry.</p><p><strong>Results: </strong>Our results present most data from gastrointestinal surgery (2,132 cases), followed by procedures from gynaecology (609 cases) and urology (498 cases). Overall, we found a conversion rate of 4.5% (147 cases). Robotic malfunctions were seen in 3% (96 cases) of the procedures, with console malfunctions occurring in 0.5% (16 cases), monitor or camera issues affecting 0.5% (17 cases), and other malfunctions registered in 2.1% (69 cases). The most common robotic limitations were displayed by limited motion (15.6%, 505 cases) and collisions (6.2%, 202 cases). Finally, we found a 3.9% rate of adverse events, with 127 episodes across all three disciplines. Most adverse events were judged as mild in severity (53 cases) and unrelated (101 cases) to the robotic system. Additionally, only one case was considered to be certainly related to the Senhance™ Robotic System, and just three serious adverse events occurred intraoperatively.</p><p><strong>Conclusion: </strong>In conclusion, our data demonstrates that performing gastrointestinal, gynaecological, and urological surgeries with the Senhance™ Robotic System can be safe for patients and surgeons.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"218"},"PeriodicalIF":2.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgi Kalev, Sylvia Buettner, Mohamad El-Ahmar, Christoph Reissfelder, Steffen Seyfried, Georgi Vassilev, Julia Hardt
{"title":"Reconstruction of the perineal defect after abdominoperineal resection with vertical rectus abdominis myocutaneous (VRAM) flap versus primary direct closure - a single center retrospective cohort study.","authors":"Georgi Kalev, Sylvia Buettner, Mohamad El-Ahmar, Christoph Reissfelder, Steffen Seyfried, Georgi Vassilev, Julia Hardt","doi":"10.1007/s00423-025-03804-7","DOIUrl":"10.1007/s00423-025-03804-7","url":null,"abstract":"","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"217"},"PeriodicalIF":2.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Abdelsamad, Mohammed Khaled Mohammed, Ibrahim Khalil, Zeyad M Wesh, Omar A Ahmed, Ahmed Elsherif, Jawad J F Alqedra, Khaled Ashraf Mohamed, Eslam Elmaghraby, Torsten Herzog, Florian Gebauer
{"title":"Continuous vs. interrupted suturing in hepaticojejunostomy: a comprehensive systematic review and meta-analysis.","authors":"Ahmed Abdelsamad, Mohammed Khaled Mohammed, Ibrahim Khalil, Zeyad M Wesh, Omar A Ahmed, Ahmed Elsherif, Jawad J F Alqedra, Khaled Ashraf Mohamed, Eslam Elmaghraby, Torsten Herzog, Florian Gebauer","doi":"10.1007/s00423-025-03756-y","DOIUrl":"10.1007/s00423-025-03756-y","url":null,"abstract":"<p><strong>Background: </strong>Hepaticojejunostomy (HJ) is a crucial reconstructive step in upper gastrointestinal (UGI), pancreaticoduodenectomy (PD), and Hepaticobiliarypancreatic (HBP) surgeries. The optimal suturing technique remains debated, with conflicting evidence regarding operative efficiency, costs, and complications. This meta-analysis compares continuous and interrupted suturing to provide evidence-based recommendations.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted using PubMed, Embase, and Cochrane Library. Primary outcomes were anastomotic time and costs, while secondary outcomes included bile leakage, anastomotic stricture, morbidity, cholangitis, hospital stay, and re-exploration rates. A random or fixed-effects model was applied based on heterogeneity. We included randomized controlled trials and non-randomized cohort studies. The risk of bias was assessed using the Cochrane ROB 2 tool, Newcastle-Ottawa Scale (NOS), and MINORS instrument as appropriate. Additionally, the quality of evidence for each outcome was evaluated using the GRADE approach. Sensitivity analyses were performed using the leave-one-out method.</p><p><strong>Results: </strong>Seven studies (1,159 patients) were included (continuous: 388, interrupted: 771). Continuous suturing significantly reduced anastomotic time (MD = -13.06 min, 95% CI: -17.37 to -8.75, P < 0.001) and costs (SMD = -4.89, 95% CI: -6.10 to -3.67, P < 0.001). However, no significant differences were observed in bile leakage, anastomotic stricture, morbidity, cholangitis, hospital stay, or re-exploration rates (P > 0.05). Sensitivity analyses confirmed these findings.</p><p><strong>Conclusion: </strong>Continuous suturing reduces anastomotic time by ~ 13 min and costs by ~ $90 without increasing complications. While these differences may be statistically significant, their clinical relevance can vary depending on the surgical context. Surgical choice should consider surgeon expertise, institutional protocols, and patient factors. Further randomized controlled trials are necessary to validate these findings.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"214"},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix von Bechtolsheim, Mareike Spindler, Veith Jungmann, Florian Oehme, Jürgen Weitz, Thilo Welsch, Benjamin Müssle
{"title":"Predictive factors for the detection of occult metastases during staging laparoscopy in patients with gastric carcinoma and adenocarcinoma of the esophagogastric junction.","authors":"Felix von Bechtolsheim, Mareike Spindler, Veith Jungmann, Florian Oehme, Jürgen Weitz, Thilo Welsch, Benjamin Müssle","doi":"10.1007/s00423-025-03783-9","DOIUrl":"10.1007/s00423-025-03783-9","url":null,"abstract":"<p><strong>Introduction: </strong>Peritoneal metastasis can occur in all stages of gastric cancer (GC) and adenocarcinoma of the esophagogastric junction (AEG) but staging laparoscopy (SL) is recommended for advanced stages. This study aimed to evaluate predictive factors for the detection of further, previously unknown (occult) metastases during SL.</p><p><strong>Materials & methods: </strong>We conducted a retrospective analysis of patients who underwent SL at our center between 2005 and 2018. Binary logistic regression analysis was used to identify risk factors for the occurrence of occult metastasis.</p><p><strong>Results: </strong>A total of 232 patients were included in the analysis. Occult metastases were detected in 48 (20.7%) patients. Forty patients (17.2%) had peritoneal carcinomatosis, 4 (1.6%) had liver metastases, 3 (1.2%) had peritoneal and liver metastases, and 1 (0.4%) had omental metastases. Univariate analysis revealed that cT4 category; cM-positivity; WHO G3 grade; histology results revealing diffuse, mixed or undifferentiated Lauren subtypes; and signet ring cells were significant risk factors for occult metastasis. Multivariate analysis confirmed that cM-positive stage (OR: 17.672; 95% CI: 3.06 to 102.052; p = 0.001) and signet ring cell count (OR: 6.228; 95% CI: 1.151 to 33.716; p = 0.034) were independently associated with occult metastasis detection by SL.</p><p><strong>Conclusion: </strong>Occult metastases are common in patients with GC or AEG who undergo SL. Histological evidence of signet ring cells should be considered a high-risk histology result and should be an independent indication for SL. Patients with positive cM staging might benefit from SL because of the high probability of further occult metastases.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"215"},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of indocyanine green fluorescence angiography in laparoscopic sleeve gastrectomy: preliminary results.","authors":"Rongwei Wei, Yonglin Li, Qi Zheng, Jing Wang, Chengyu Wu, Xiaojing Lu, Ziliang Zong, Yigang Chen","doi":"10.1007/s00423-025-03792-8","DOIUrl":"10.1007/s00423-025-03792-8","url":null,"abstract":"<p><strong>Background: </strong>In recent years, as researchers have discovered that indocyanine green (ICG) near-infrared fluorescence imaging offers excellent tissue penetration, the application of ICG fluorescence angiography (ICG-FA) in various laparoscopic procedures has become increasingly widespread and gets significant therapeutic efficacy. However, its use in laparoscopic sleeve gastrectomy (LSG) has not been extensively reported.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted on the clinical data of 291 patients who underwent LSG at our clinical medical center between September 2021 and November 2024. The patients were divided into two groups: Group A, consisting of 195 cases (without intraoperative use of ICG-FA), and Group B, comprising 96 cases (with intraoperative use of ICG-FA). Statistical software was utilized for data processing and analysis.</p><p><strong>Results: </strong>The mean blood loss along the staple line was 6.53 ± 1.69 mL in Group A and 2.57 ± 1.81 mL in Group B (p < 0.001). The mean operative time was 99.01 ± 22.63 min in Group A and 94.04 ± 22.88 min in Group B (p < 0.05). The mean hospital stay was 5.89 ± 1.48 days in Group A and 4.95 ± 2.92 days in Group B (p < 0.001). Among all 291 patients, there were 2 cases of gastric leakage, with 1 case occurring in each group, 4 patients experienced postoperative bleeding, with 2 cases occurring in each group.</p><p><strong>Conclusions: </strong>Findings from our institutional data indicate that while ICG-FA demonstrated statistically significant reductions in staple line bleeding (due to suture needle punctures), shorter mean operative time, and decreased average hospital stay, its clinical benefits in LSG for morbid obesity appear limited compared to its established utility in other laparoscopic procedures. Furthermore, ICG-FA did not reduce the incidence of postoperative complications, such as gastric leaks or bleeding.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"213"},"PeriodicalIF":2.1,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12226696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}