The effect of pre-operative MRI on the in-breast tumor recurrence rate of patients with breast cancer: a meta-analysis.

IF 2.1 3区医学 Q2 SURGERY

Langenbeck's Archives of Surgery Pub Date : 2025-04-04 DOI:10.1007/s00423-025-03691-y

Mahdieh Khoshzaban Banisi, Hani Ghadri, Behnaz Soltani, Amirali Farshid, Bahar Behnam, Amir Abbas Rhouholamini, Amirhossein Mohammadi, Seyedeh Fatemeh Hamzavi, Ashkan Azizi, Niloofar Deravi, Masoud Noroozi, Amin Magsudy, Sina Seyedipour, Shima Behzad, Yaser Khakpour

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引用次数: 0

Abstract

Purpose: The impact of preoperative MRI on breast cancer recurrence and long-term outcomes remains undefined. Therefore, this study aims at determining the influence of preoperative MRI on in-breast tumor recurrence rates in cases of surgical treatment for breast cancer.

Methods: A systematic review and meta-analysis were performed. Literature searches of PubMed, Scopus, and Google Scholar were conducted for studies up to February 2024. Two authors assessed the quality of the eligible studies and extracted their data.

Results: The meta-analysis included 14 studies (2 RCTs, 12 cohort studies) with 12,889 patients with 5,451 undergoing preoperative MRI. Pooled hazard ratio for in-breast tumor recurrence was 0.95, using fixed effects and 0.94 using random effects models with 95% confidence intervals of 0.80-1.14 and 0.77-1.14, respectively. A trend towards lower recurrence rates in the MRI group was seen, but the reduction was not statistically significant.

Conclusion: This meta-analysis found no significant reduction in in-breast tumor recurrence rates associated with preoperative MRI use in breast cancer patients, consistent with previous findings.

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目的：术前磁共振成像对乳腺癌复发和长期预后的影响仍未确定。因此，本研究旨在确定术前磁共振成像对乳腺癌手术治疗病例中乳腺肿瘤复发率的影响：方法：进行系统回顾和荟萃分析。在 PubMed、Scopus 和 Google Scholar 上检索了截至 2024 年 2 月的文献。两位作者对符合条件的研究进行了质量评估并提取了数据：荟萃分析纳入了14项研究（2项RCT研究，12项队列研究），共有12889名患者接受了术前磁共振成像检查，其中5451名患者接受了术前磁共振成像检查。采用固定效应和随机效应模型得出的乳腺内肿瘤复发危险比分别为0.95和0.94，95%置信区间分别为0.80-1.14和0.77-1.14。磁共振成像组的复发率呈下降趋势，但下降幅度在统计学上并不显著：这项荟萃分析发现，乳腺癌患者术前使用核磁共振成像并不会显著降低乳腺肿瘤复发率，这与之前的研究结果一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Langenbeck's Archives of Surgery 医学-外科

CiteScore

3.30

自引率

8.70%

发文量

342

审稿时长

4-8 weeks

期刊介绍： Langenbeck''s Archives of Surgery aims to publish the best results in the field of clinical surgery and basic surgical research. The main focus is on providing the highest level of clinical research and clinically relevant basic research. The journal, published exclusively in English, will provide an international discussion forum for the controlled results of clinical surgery. The majority of published contributions will be original articles reporting on clinical data from general and visceral surgery, while endocrine surgery will also be covered. Papers on basic surgical principles from the fields of traumatology, vascular and thoracic surgery are also welcome. Evidence-based medicine is an important criterion for the acceptance of papers.