Journal of VitreoRetinal Diseases最新文献

{"title":"Combined Treatment With Inverted Internal Limiting Membrane Flap and Subretinal Injection of Balanced Salt Solution to Repair Chronic Macular Holes.","authors":"Akira Kanai, Jun Takeuchi, Takashi Koto, Makoto Inoue","doi":"10.1177/24741264241278434","DOIUrl":"10.1177/24741264241278434","url":null,"abstract":"<p><p><b>Purpose:</b> To present a surgical technique that combines an inverted internal limiting membrane (ILM) flap and subretinal injection of balanced salt solution for the closure of chronic macular holes (MH). <b>Methods:</b> Two cases are presented. <b>Results:</b> A 74-year-old man and a 63-year-old woman presented with decreased visual acuity (VA) of 20/600 and 20/200, respectively, resulting from a chronic MH. Both patients had vitrectomy, during which the ILM flap was inverted and a 38-gauge subretinal needle was used to inject balanced salt solution near the vascular arcade, creating a retinal bleb. Injection of the balanced salt solution into the MH with a backflush needle completed the detachment. The MH was then closed by a gas tamponade with improvements in VA in both patients to 20/50 and 20/40, respectively. <b>Conclusions:</b> The combined inverted ILM flap and subretinal injection of balanced salt solution into the MH, extending the detachment, led to the successful closure of a chronic MH.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241278434"},"PeriodicalIF":0.5,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging-Guided Classification of Neovascularization in Neovascular Age-Related Macular Degeneration: Progress to Date.","authors":"Giovanni Staurenghi, Eric H Souied, Tomohiro Iida, David R Chow, Armin Wolf, Roberto Gallego-Pinazo, Francesco Viola, Peter K Kaiser","doi":"10.1177/24741264241276929","DOIUrl":"10.1177/24741264241276929","url":null,"abstract":"<p><p><b>Purpose:</b> To review the evolution of terminology describing the classification of lesions in neovascular age-related macular degeneration (nAMD) based on retinal imaging technologies. <b>Methods:</b> A review of the current and historical literature on imaging-guided classification of neovascularization in nAMD was performed. <b>Results:</b> Imaging-guided classification of neovascularization in nAMD facilitates understanding of the pathological mechanisms and disease progression. Neovascularization classification has evolved with advances in imaging technologies, from earlier classifications based on neovascularization patterns assessed by fluorescein angiography to multimodal imaging patterns, resulting in varied descriptions of lesions depending on the techniques used. Until recently, there has been a lack of consensus regarding the clinical features of choroidal neovascularization lesion types as a result of the imaging modalities initially used to define them; a recent consensus on classification has the potential to simplify and clarify descriptions of neovascularization in nAMD. The use of multimodal imaging techniques will improve lesion identification and has the potential to individualize treatment plans and improve outcomes. <b>Conclusions:</b> Widespread adoption of a consensus-based, image-guided classification system for neovascular lesions in nAMD and the appropriate imaging techniques used to identify them will aid clinical research and could potentially improve patient outcomes by individualizing treatment plans in the future.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241276929"},"PeriodicalIF":0.5,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photoreceptor Characteristics in Diabetic Retinopathy vs Controls Using Adaptive Optics Imaging: Systematic Review.","authors":"Justin Grad, Amin Hatamnejad, Niveditha Pattathil, John Golding, Netan Choudhry","doi":"10.1177/24741264241286682","DOIUrl":"10.1177/24741264241286682","url":null,"abstract":"<p><p><b>Purpose:</b> To assess the differences in morphological photoreceptor outcomes measured using adaptive optics (AO)-assisted imaging between individuals with diabetes or prediabetes and healthy controls. <b>Methods:</b> A systematic search was conducted across MEDLINE, Embase, and Cochrane databases from January 2000 to June 2023. Studies that used AO-assisted imaging modalities to quantitatively compare photoreceptor outcomes in patients with diabetes or prediabetes with healthy controls were included. <b>Results</b>: Eleven studies consisting of 551 eyes were included. Most studies reported significant differences in photoreceptor outcomes between diabetic and healthy populations, particularly as diabetic retinopathy (DR) severity increased. Cone regularity was the most sensitive parameter for detecting significant differences between groups. AO imaging was less reliable in distinguishing individuals with diabetes without DR or with mild DR severity from controls. <b>Conclusions:</b> AO imaging showed promise in detecting significant differences associated with diabetes and DR, in particular with increasing disease severity. Further research is warranted to assess AO's utility as a diabetes and DR screening tool. Standardizing imaging protocols in future studies is recommended to allow for more direct quantitative comparisons. These findings highlight the current evidence on photoreceptor changes in patients with diabetes and the potential of AO in advancing diabetic eye care.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241286682"},"PeriodicalIF":0.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Presentation and Treatment Outcomes of Adult-Onset Coats Disease.","authors":"Saarang Hansraj, Vishal Raval, Subhadra Jalali, Niroj Sahoo, Anthony Vipin Das","doi":"10.1177/24741264241286580","DOIUrl":"10.1177/24741264241286580","url":null,"abstract":"<p><p><b>Purpose:</b> To study the clinical profile, treatment, and outcomes of patients 35 years or older diagnosed with Coats disease. <b>Methods:</b> A cross-sectional observational hospital-based study was performed. <b>Results:</b> The study included 74 eyes diagnosed with adult-onset Coats disease. The mean age at presentation was 50 years (range, 35-75). Most patients were men (72.5%) and had a unilateral presentation (92.8%). The most common stage at presentation was 2A (extrafoveal exudation) (39.2%) followed by 2B (foveal exudation (33.7%). Optical coherence tomography was performed in 40 eyes; 32 eyes (80.0%) had intraretinal fluid (IRF), 31 eyes (77.5%) had hard exudates, and 22 eyes (55.0%) had a disorganized retinal inner layer. Fluorescein angiography was performed in 35 eyes and showed an irregular foveal avascular zone in 28 eyes (80.0%). Multiple leaking microaneurysms were seen in 32 eyes (91.4%), with extensive vascular abnormalities involving the macula (86%) and extramacular zones (91%). Treatment modalities comprised laser photoablation (43.4%), cryotherapy with or without laser application (5.7%), and intravitreal injections (49%), alone or in combination. At a mean follow-up of 28 months (range, 3-293), 23 eyes (39.6%) had anatomic resolution of subretinal fluid and/or IRF. No statistical improvement was found in the mean best-corrected visual acuity (VA) between preoperatively and postoperatively (<i>P</i> > .05). <b>Conclusions:</b> Patients with adult-onset Coats disease have a unilateral presentation with a less severe stage than patients with childhood-onset disease. Despite the good anatomic responses after treatment, the final VA remained unchanged.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241286580"},"PeriodicalIF":0.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macular, Choroidal, and Peripapillary Perfusion Changes in Mild and Moderate Traumatic Brain Injury Using Optical Coherence Tomography and Angiography.","authors":"Grant A Justin, Lauren Winslow, Anita Kundu, Cason B Robbins, Praruj Pant, S Tammy Hsu, Chantal J Boisvert, Nathan T Tagg, Sandra S Stinnett, Rupesh Agrawal, Dilraj S Grewal, Sharon Fekrat","doi":"10.1177/24741264241275272","DOIUrl":"10.1177/24741264241275272","url":null,"abstract":"<p><p><b>Introduction:</b> To compare the retinal and choroidal architecture and microvasculature between patients with mild or moderate traumatic brain injury (TBI) and controls with normal cognition using optical coherence tomography (OCT) and OCT angiography (OCTA). <b>Methods:</b> Patients with a documented history of TBI, and age-matched and sex-matched controls were recruited. The primary outcome measures were differences between OCT parameters, including the choroidal vascularity index, and between OCTA superficial capillary plexus metrics, including foveal avascular zone (FAZ) circularity, 3.0 mm × 3.0 mm and 6.0 mm × 6.0 mm macular vessel density and perfusion density, and 4.5 mm × 4.5 mm peripapillary capillary perfusion density and capillary flux index. <b>Results:</b> Sixty-seven eyes of 36 patients with TBI and 72 eyes of 36 control patients met the inclusion criteria. Twelve patients (33.3%) had a diagnosis of mild TBI without loss of consciousness (LOC), 21 (58.3%) had mild TBI with LOC, and 3 (8.3%) had moderate TBI. There was a significant reduction in FAZ circularity and in 3.0 mm × 3.0 mm macular OCTA vessel density and perfusion density in patients with TBI. In cases with TBI associated with posttraumatic stress disorder, all macular OCTA parameters were significantly reduced. There was an increase in the choroidal vascularity index across the severity of TBI; however, it was reduced in those with more than 1 TBI (<i>P</i> = .03). <b>Conclusions:</b> There was a reduction in macular perfusion in eyes of patients with mild or moderate TBI. The choroidal vascularity index helps differentiate subtle effects of more severe or mild repeated TBI. Further prospective investigation will evaluate OCT imaging and OCTA imaging as a noninvasive screening modalities to assess changes in retinal and choroidal microvasculature.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241275272"},"PeriodicalIF":0.5,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Diffuse Uveal Melanocytic Proliferation in the Setting of Ovarian Cancer.","authors":"Matthew Olis, Thomas A Weppelmann, Mamta Patel","doi":"10.1177/24741264241278822","DOIUrl":"10.1177/24741264241278822","url":null,"abstract":"<p><p><b>Purpose:</b> To describe a case of bilateral diffuse uveal melanocytic proliferation in the setting of metastatic ovarian cancer. <b>Methods:</b> A single case was analyzed and a literature review of treatment efficacy performed. <b>Results</b>: A 64-year-old woman presented to ophthalmology in July 2022 for evaluation of blurred vision in the setting of ovarian cancer and a possible reaction to chemotherapy. A comprehensive workup led to the diagnosis of bilateral diffuse uveal melanocytic proliferation. Treatment to potentially preserve the patient's vision comprised a sub-Tenon triamcinolone injection and plasmapheresis. <b>Conclusions:</b> Plasmapheresis did not improve the visual acuity (VA) in the patient's right eye; however, 6 months after the last treatment, the VA in the left eye improved from 20/50 to 20/30, corresponding to a decrease in macular edema. Given the rarity of bilateral diffuse uveal melanocytic proliferation, its uncertain pathogenesis, and its varied responses to treatment, it is imperative to establish a diagnostic management and treatment algorithm to improve visual outcomes.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241278822"},"PeriodicalIF":0.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myopia Support Device (Titanium Macular Buckle) for Posterior Pole Retinal Detachment With or Without Myopic Maculoschisis.","authors":"Levent Akduman, Sengul Ozdek, Serhat Ermis, Ece Ozdemir-Zeydanli, Ozgur Artunay, Mohsen Abou Shousha","doi":"10.1177/24741264241276264","DOIUrl":"10.1177/24741264241276264","url":null,"abstract":"<p><p><b>Purpose:</b> To describe 4 cases of posterior pole retinal detachment (RD) in patients with pathologic myopia that were repaired with a prototype myopia support device. <b>Methods:</b> A case series was evaluated. <b>Results:</b> Four cases of posterior pole RD were treated, 3 of which were accompanied by myopic maculoschisis and 1 that was accompanied by a choroidal neovascular membrane and a macular hole (MH). Preoperative and postoperative assessments included visual acuity, optical coherence tomography and fluorescein angiography findings, and axial lengths when available. Three patients had vitrectomy and device placement, while the other patient received device placement alone. All cases had successful repair of the RD, with complete resolution of maculoschisis and MH when present. The myopia support device provided the desired indentation, aiding in the repair. Follow-up varied between 2 months and 17 months. <b>Conclusions:</b> The myopia support device is a valuable addition for repair of posterior pole RDs in patients with pathologic myopia, with or without maculoschisis or MH. It can be used in conjunction with vitrectomy or as a standalone technique.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241276264"},"PeriodicalIF":0.5,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the Editor-in-Chief.","authors":"Timothy G Murray","doi":"10.1177/24741264241278446","DOIUrl":"https://doi.org/10.1177/24741264241278446","url":null,"abstract":"","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":"8 5","pages":"493-497"},"PeriodicalIF":0.5,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142349353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomic and Visual Outcomes of Scleral Buckle in Primary Rhegmatogenous Retinal Detachment in the Era of Pars Plana Vitrectomy.","authors":"Naresh Babu Kannan, Kulsum J Sayyad, Muthu Krishnan Vallinayagam, Chitaranjan Mishra, Keya Chakrabarti, Priyalaxmi Chakpram, Kim Ramasamy","doi":"10.1177/24741264241275009","DOIUrl":"10.1177/24741264241275009","url":null,"abstract":"<p><p><b>Introduction:</b> To determine the presenting clinical characteristics of patients with rhegmatogenous retinal detachment (RRD) who underwent scleral buckling and the impact on final visual outcomes and to determine the postoperative primary attachment rate, complications, and subsequent management. <b>Methods:</b> This retrospective observational study comprised patients with RRD who had scleral buckling surgery from January 2016 to December 2021 with a minimum follow-up of 6 months. <b>Results:</b> The study comprised 307 eyes of 290 patients; 97% of eyes were phakic. Primary anatomic attachment was achieved in 93% of eyes. Macula-on detachment had a significant relationship with visual gain, while age, refractive status, number of breaks, configuration of the detachment, traumatic etiology, and lens status did not. Eyes with recurrent detachment did not have a significant visual gain after subsequent pars plana vitrectomy (PPV). <b>Conclusions:</b> Most eyes that underwent scleral bucking were phakic. Macular status played a significant role in the visual prognosis. The primary anatomic attachment rate after scleral buckling surgery is comparable to that after PPV. Thus, scleral buckling is far from being a procedure of the past. Multiple breaks, inferior detachments, and traumatic etiology do not appear to adversely affect the visual outcomes. Multiple vitreoretinal surgeries may not result in a visual gain in cases of recurrent detachment.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241275009"},"PeriodicalIF":0.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serial OCT Imaging of Spontaneous Closure of a Pediatric Traumatic Macular Hole.","authors":"Andrew S H Tsai, Aaron R Kaufman, R V Paul Chan","doi":"10.1177/24741264241275275","DOIUrl":"10.1177/24741264241275275","url":null,"abstract":"<p><p><b>Purpose:</b> To describe a case of spontaneous closure of a pediatric traumatic macular hole (MH) using serial optical coherence tomography (OCT) imaging. <b>Methods:</b> A single case was evaluated. <b>Results:</b> An 8-year-old girl developed a full-thickness MH in the right eye after sustaining blunt trauma from a bungee cord. She was observed monthly. By 3 months, the MH spontaneously closed, at which time an epiretinal membrane (ERM) developed. Spontaneous release of the posterior hyaloid and ERM at 5 months resulted in a relatively normal foveal contour. At the patient's last follow-up, the visual acuity in the right eye had improved from 20/80 to 20/30. <b>Conclusions:</b> Observation of a pediatric traumatic MH is a viable initial treatment option. Serial OCT imaging was useful in observing the natural history and mechanism behind spontaneous closure of a traumatic MH.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264241275275"},"PeriodicalIF":0.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}