Klinicka mikrobiologie a infekcni lekarstvi最新文献_第5页

[Clinical progression of the first wave of novel coronavirus infection in Ostrava]. 俄斯特拉发省第一波新型冠状病毒感染的临床进展

Klinicka mikrobiologie a infekcni lekarstvi Pub Date : 2020-09-01

Lenka Petroušová, Simona da Silva, Luděk Rožnovský, Irena Martinková

{"title":"[Clinical progression of the first wave of novel coronavirus infection in Ostrava].","authors":"Lenka Petroušová, Simona da Silva, Luděk Rožnovský, Irena Martinková","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: The first case of coronavirus infection in the Moravian-Silesian Region was diagnosed on March 12, 2020. The study aimed to describe the first wave and clinical manifestation of the coronavirus epidemic at the Department of Infectious Diseases in Ostrava.Material and methods: The sample comprised a total of 195 patients requiring hospitalization at the Department of Infectious Diseases in Ostrava between March 1 and August 31, 2020. The virus was diagnosed using polymerase chain reaction from nasopharyngeal swabs in 192 patients and from the bronchoalveolar lavage in one patient. In the other two patients, serological tests were applied using virus neutralization assays and ELISA specific antibodies.Results: The sample included 100 men and 95 women. The mean age was 69.5 years. The most common diagnosis was pneumonia, observed in 123 patients (63 %). Respiratory symptoms without pneumonia were seen in 37 patients (19 %); loss of smell and taste in 14 patients (7 %); cardiovascular complications in 9 patients (5 %); acute psychosis in 2 patients (1 %); and diarrhea and vomiting in 25 patients (13 %). The remaining 23 patients (12 %) did not present any symptoms. The mean length of hospital stay was 11 days. The most frequent comorbidity was cardiovascular disease (70 %). A total of 39 patients died (20 %); their mean age was 77 years. Mechanical ventilation was started in 16 patients, of whom 7 died (43 %). The treatment was mostly symptomatic. Hydroxychloroquine was administered to 21 patients (11 %), favipiravir to 26 patients (13 %) and remdesivir to 13 patients (6 %).Conclusion: Respiratory complications predominated in the majority of patients with coronavirus infection. In most cases, the treatment was symptomatic. One-fifth of the patients, mostly elderly ones, died.","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"26 3","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38797491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Two case reports of chronic hepatitis C retreatment]. 【慢性丙型肝炎再治疗2例报告】。

Klinicka mikrobiologie a infekcni lekarstvi Pub Date : 2020-09-01

Luděk Rožnovský, Jakub Mrázek, Lenka Petroušová, Irena Orságová, Libuše Kabieszová, Michaela Konečná, Alena Kloudová

引用次数: 0

[Chromoblastomycosis and phaeohyphomycosis, overlooked fungal diseases]. [嗜色菌病和褐丝菌病，被忽视的真菌疾病]。