Klinicka mikrobiologie a infekcni lekarstvi最新文献

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[Case report of fatal sepsis caused by Actinobacillus suis/equuli in an adult male]. [1例成年男性猪/马放线杆菌致致命性败血症报告]。
Petr Ježek, Lucia Mališová, Renáta Šafránková
{"title":"[Case report of fatal sepsis caused by Actinobacillus suis/equuli in an adult male].","authors":"Petr Ježek,&nbsp;Lucia Mališová,&nbsp;Renáta Šafránková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This is a case report of sepsis caused by the species Actinobacillus suis/equuli in a male agriculture worker that ended fatally. The article also contains information on identification and results of antibiotic susceptibility testing. This is a rare case of human infection and probably the first case of a human being infected by this species in the Czech Republic.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"45-47"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10411668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Digitalization in clinical microbiology]. [临床微生物学数字化]。
Milan Kolář
{"title":"[Digitalization in clinical microbiology].","authors":"Milan Kolář","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Reflections on digitalization in clinical microbiology are presented. The advantages and limitations of digital processing of microbiological data for individuals and the human population are considered.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10411674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pharmacological properties of colistin]. [粘菌素的药理特性]。
Jitka Rychlíčková, Vendula Kubíčková
{"title":"[Pharmacological properties of colistin].","authors":"Jitka Rychlíčková,&nbsp;Vendula Kubíčková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colistin is a narrow-spectrum lipopeptide antimicrobial agent used to treat nosocomial infections caused by multidrug-resistant bacteria, especially in critically ill patients and those with cystic fibrosis. Colistin represents a concentration-time-dependent antibiotic with highly variable pharmacokinetics related to the heterogeneity of the target population and the necessity of bioactivation. Colistin is administered as the inactive prodrug colistimethate sodium. Nephrotoxicity and neurotoxicity are the most frequent adverse effects.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10420315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Poultry as a reservoir of zoonotic strains of Escherichia coli]. [家禽是大肠杆菌人畜共患菌株的储存库]。
Aneta Papoušková
{"title":"[Poultry as a reservoir of zoonotic strains of Escherichia coli].","authors":"Aneta Papoušková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Poultry and poultry products are considered a potentially significant source of resistant E. coli strains and their determinants encoded by mobile genetic elements, such as genes for ESBL/AmpC beta-lactamases. Poultry also hosts extraintestinal pathogenic E. coli strains (ExPEC). The similarity of poultry avian pathogenic E. coli to human strains has led to the inclusion of ExPEC among bacteria with zoonotic potential. However, population diversity of E. coli pathotypes, host specificity and circulation of diverse strains and genetic determinants between populations are rather complex and the aforementioned risks cannot be addressed separately.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"42-44"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10411671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Can a difficult-to-treat resistance approach improve cooperation between microbiologists and clinicians?] 难以治疗的耐药方法能改善微生物学家和临床医生之间的合作吗?]
Gabriela Kroneislová, Jan Závora, Váslava Adámková
{"title":"[Can a difficult-to-treat resistance approach improve cooperation between microbiologists and clinicians?]","authors":"Gabriela Kroneislová,&nbsp;Jan Závora,&nbsp;Váslava Adámková","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We introduce a relatively new difficult-to-treat resistance (DTR) category to specialists. It significantly influences the predictability of morbidity and mortality in patients with invasive infections caused by DTR strains. Therefore, surveillance of DTR is an important tool of antimicrobial stewardship (AMS) and widely contributes to cooperation between microbiologists and clinicians. We also report the prevalence of strains meeting the criteria for the category in a teaching hospital.</p><p><strong>Methods: </strong>This retrospective cohort single center study included invasive isolates of gram-negative rods from patients hospitalized in the General University Hospital in Prague in 2009-2013 and in 2017-2021.</p><p><strong>Results: </strong>From a total of 1 732 (920 and 812, respectively) unique strains of gram-negative rods isolated from blood cultures in both periods, 6.6 % were carbapenem-resistant in 2009-2013 and 6.0 % in 2017-2021; 3.7 % were identified as DTR in both periods. Most of the DTR strains were A. baumannii (23.1 % and 45.0 %, respectively) and P. aeruginosa (22.2 % and 15.3 %, respectively). We identified no carbapenem-resistant E. coli and therefore no DTR E. coli.</p><p><strong>Conclusion: </strong>Infections caused by bacterial strains with a DTR phenotype are grave complications and are tricky to manage. The prevalence of severe infections caused by these strains was relatively low in the studied facility. Antibiotics with anti-DTR effects should be considered the last resort, so it is very important to comply with AMS rules and examine the susceptibility of these agents.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"52-58"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10420316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Impact of the COVID-19 pandemic on antimicrobial resistance]. [COVID-19大流行对抗菌素耐药性的影响]。
Kateřina Fišerová, Lenka Doubravská, Miroslava Htoutou Sedláková, Milan Kolář
{"title":"[Impact of the COVID-19 pandemic on antimicrobial resistance].","authors":"Kateřina Fišerová,&nbsp;Lenka Doubravská,&nbsp;Miroslava Htoutou Sedláková,&nbsp;Milan Kolář","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic has had a major impact on the healthcare system, which has been forced to manage large numbers of patients, including those with respiratory insufficiency and in need of oxygen therapy. Due to concerns about bacterial co-infection, antibiotic therapy was administered to many patients. The aim of the present study was to compare antimicrobial resistance in intensive care patients in the pre-pandemic and pandemic periods.</p><p><strong>Material and methods: </strong>Patients hospitalized at the Department of Anesthesiology, Resuscitation and Intensive Care Medicine of the University Hospital Olomouc in the pre-COVID-19 period (2018-2019) and during the pandemic (2020-2021) were enrolled in the study. Clinical samples from the lower respiratory tract were routinely collected twice a week, with one strain of a given species first isolated from each patient being included in the study.</p><p><strong>Results: </strong>While several bacterial species (Escherichia coli, Proteus mirabilis and Haemophilus influenzae) were found to occur less frequently, an increased occurrence was documented for Enterococcus faecium, Serratia marcescens and Klebsiella variicola. Overall, however, it can be concluded that there was no major change in the frequency of bacterial pathogens isolated from the lower respiratory tract during the COVID-19 period. Similarly, with only a few exceptions, antimicrobial resistance did not change significantly. More significant increases in resistance to piperacillin/tazobactam, cefotaxime, ciprofloxacin and gentamicin have been demonstrated for Serratia marcescens. However, a decrease in the resistance of Pseudomonas aeruginosa and Burkholderia cepacia complex to meropenem was also observed.</p><p><strong>Conclusions: </strong>There was no significant change in the frequency of bacterial pathogens and their resistance to antibiotics during the COVID-19 pandemic. However, there was an increase or decrease in the percentage of some species and in their resistance.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 2","pages":"36-41"},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10411676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Trichomonas vaginalis - the culprit or the accomplice?] 阴道毛滴虫——罪魁祸首还是帮凶?]
Petra Myšková, Petra Kubáčková, Petr Janků
{"title":"[Trichomonas vaginalis - the culprit or the accomplice?]","authors":"Petra Myšková,&nbsp;Petra Kubáčková,&nbsp;Petr Janků","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The case reports describes detection of Trichomonas vaginalis in a 34-year-old patient with preterm prelabor rupture of membranes and a subsequent C-section in week 25 of her pregnancy, with the presence of T. vaginalis not being the only risk factor for preterm labor. Although a rare finding in pregnant women, the presence of this microorganism must be considered in such situations.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 1","pages":"25-26"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40387380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pulmonary complications following COVID-19 infection]. 【COVID-19感染后肺部并发症】。
Petr Jakubec, Samuel Genzor
{"title":"[Pulmonary complications following COVID-19 infection].","authors":"Petr Jakubec,&nbsp;Samuel Genzor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the relatively short period of time since December 2019, hundreds of millions of people globally have been infected with SARS-CoV-2, irrespective of their age, gender or ethnicity. Over that time, numerous mutations of various degrees of virulence and pathogenicity have occurred. The course of COVID-19 infection, an acute disease caused by the virus, is rather varied, ranging from asymptomatic or symptoms of common viral respiratory diseases to critical, with multiorgan failure and high mortality in high-risk patients. The overall mortality of the disease is 1-2 %. Unlike other viral respiratory diseases, this infection is often associated with frequent and rather diverse clinical manifestations developing after the acute phase of the infection, that is, more than 28 days after its onset. These complications are observed in both individuals with mild illness treated at home and inpatients with severe to critical illness. They develop both early after acute infection and some time after recovering from the disease. This rather heterogeneous group of pathologies may affect various organs and organ systems, with respiratory tract involvement being the most common and one of the most serious complications. Severe respiratory post-COVID-19 complications often include respiratory tract infections, in particular pneumonia.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40385975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Imipenem-cilastatin-relebactam used to treat ventilator-associated pneumonia developing after infection with SARS-CoV-2]. [亚胺培南-西司他汀-瑞巴坦用于治疗SARS-CoV-2感染后发生的呼吸机相关性肺炎]。
Ondřej Zahornacký, Štefan Porubčin, Alena Rovňáková, Pavol Jarčuška
{"title":"[Imipenem-cilastatin-relebactam used to treat ventilator-associated pneumonia developing after infection with SARS-CoV-2].","authors":"Ondřej Zahornacký,&nbsp;Štefan Porubčin,&nbsp;Alena Rovňáková,&nbsp;Pavol Jarčuška","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article describes the use of the last-resort carbapenem antibiotic imipenem in combination with relebactam, a novel b-lactamase inhibitor, in the treatment of ventilator-associated pneumonia developing after SARS-CoV-2 infection in a young pregnant patient. The introduction briefly describes the mechanism and spectrum of activity of the antibiotic, including its dosage.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 1","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40385976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Monitoring the activity of Ixodes ricinus ticks and their positivity for selected pathogenic microorganisms in the agglomeration of the city of Brno]. [监测布尔诺市聚集区蓖麻蜱的活动及其对选定病原微生物的阳性反应]。
Alena Žákovská, Alice Milotová
{"title":"[Monitoring the activity of Ixodes ricinus ticks and their positivity for selected pathogenic microorganisms in the agglomeration of the city of Brno].","authors":"Alena Žákovská,&nbsp;Alice Milotová","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>The aim is to present the results of monitoring the activity of Ixodes ricinus ticks and their positivity for dangerous pathogenic microorganisms in the Brno-Pisarky forest park. The monitored pathogens were Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, Coxiella burnetii, Erhlichia chaffensis and Francisella tularensis. Additionally, factors potentially influencing tick activity in the location (especially the temperature) were monitored.</p><p><strong>Materials and methods: </strong>In the location, ticks were caught using the flagging method. Positivity of ticks was determined by polymerase chain reaction followed by gel electrophoresis.</p><p><strong>Results: </strong>Between March and November 2021, 563 ticks were collected in the location, the vast majority being nymphs (85 %). The positivity rates were 5.6 % for the pathogen Bbsl was and 2.4 % for A. phagocytophilum. C. burnetii, E. chaffensis and F. tularensis were not confirmed in the location.</p><p><strong>Conclusion: </strong>The location was found to be infested with the pathogens Bbsl and A. phagocytophilum. However, the positivity in Brno-Pisarky is lower compared to other Brno areas.</p>","PeriodicalId":17909,"journal":{"name":"Klinicka mikrobiologie a infekcni lekarstvi","volume":"28 1","pages":"22-24"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40387379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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