Klinische Monatsblatter fur Augenheilkunde最新文献_第7页

Imbalanced Trace Elements as Risk Factors in the Pathogenesis of Glaucoma. 微量元素失衡是青光眼发病的危险因素。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-07-01 Epub Date: 2026-06-22 DOI: 10.1055/a-2805-1399

Kira Steinhorst, Petra Lakatos, Bettina Hohberger

引用次数: 0

Primäres Offenwinkelglaukom als neurodegenerative Erkrankung – Risikofaktoren und therapeutische Empfehlungen. 原发性开角青光眼作为一种神经退行性疾病：风险因素和治疗建议。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-07-01 Epub Date: 2026-07-20 DOI: 10.1055/a-2754-8830

Carl Erb, Verena Prokosch

引用次数: 0

Physical Inactivity as a Risk Factor for Neurodegeneration and Sports Medicine-based Recommendations. [缺乏运动作为神经退行性变的危险因素和运动医学建议]。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-07-01 Epub Date: 2026-02-19 DOI: 10.1055/a-2815-0976

Eva Schaeffer, Burkhard Weisser

{"title":"Physical Inactivity as a Risk Factor for Neurodegeneration and Sports Medicine-based Recommendations.","authors":"Eva Schaeffer, Burkhard Weisser","doi":"10.1055/a-2815-0976","DOIUrl":"10.1055/a-2815-0976","url":null,"abstract":"Abstract: Brain aging, many neurological diseases, and glaucoma are associated with neurodegenerative processes of varying degrees. Regular physical activity is one of the most successful non-pharmacological interventions for prevention and treatment. The mechanisms of neuroprotection through exercise and sport are becoming increasingly well understood. In addition to general anti-inflammatory and antioxidant effects, there are specific effects on neurogenesis, brain plasticity, and angiogenesis in the brain, which are also clinically associated with, among other things, reduced cognitive decline. Dozens of exerkines are now known. These are proteins or metabolites that are released during exercise and exert neuroprotective effects in the brain via specific mechanisms of action, e. g., BDNF (brain-derived neurotrophic factor) or VEGF (vascular endothelial growth factor). Intervention studies have shown that moderate endurance training, as well as specific strength training, can stimulate these and other neurobiologically relevant factors and positively influence atrophy processes in certain brain regions (e. g., the hippocampus).","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"731-735"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Photodynamic Therapy in Chronic Central Serous Chorioretinopathy: A Retrospective Analysis at Hanusch Hospital, Vienna. 光动力疗法治疗慢性中枢性浆液性脉络膜视网膜病变的疗效：维也纳Hanusch医院回顾性分析。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-07-01 Epub Date: 2026-02-10 DOI: 10.1055/a-2772-8827

Christoph Spartalis, Christoph Hackl, Stephan Radda, Oliver Findl

{"title":"Efficacy of Photodynamic Therapy in Chronic Central Serous Chorioretinopathy: A Retrospective Analysis at Hanusch Hospital, Vienna.","authors":"Christoph Spartalis, Christoph Hackl, Stephan Radda, Oliver Findl","doi":"10.1055/a-2772-8827","DOIUrl":"10.1055/a-2772-8827","url":null,"abstract":"Abstract: BACKGROUND: Chronic central serous chorioretinopathy (cCSC) is an exudative maculopathy characterised by persistent subretinal fluid and potential visual deterioration. Photodynamic therapy (PDT) with verteporfin is an established treatment option, particularly in refractory or chronic cases. This retrospective, single centre study aimed to evaluate the functional and morphological efficacy of PDT in patients with cCSC at Hanusch Hospital, Vienna.Abstract: PATIENTS/MATERIALS AND METHODS: We analysed 49 eyes of 38 patients who underwent PDT between 2020 and 2025. Best-corrected visual acuity (decimal), central retinal thickness (CRT, µm), and subretinal fluid (SRF, µm) were assessed using spectral domain OCT before and after treatment. Statistical analyses included the Shapiro-Wilk test for normality and the Wilcoxon signed-rank test for paired samples. Subgroup analyses were conducted for repeat PDT (Re-PDT) and secondary choroidal neovascularisation (CNV).Abstract: RESULTS: Overall, PDT led to a significant improvement in visual acuity (p = 0.041) and a highly significant reduction in both CRT and SRF (each p < 0.001). In the Re-PDT subgroup (n = 6), significant morphological improvement (p = 0.028 for CRT and SRF) was observed without a statistically significant gain in vision (p = 0.109). No significant therapeutic effect was found in patients with secondary CNV. There was a significant negative correlation between visual acuity and CRT (r = - 0.42; p = 0.005) and between visual acuity and SRF (r = - 0.37; p = 0.012).Abstract: CONCLUSION: PDT appears to be an effective treatment for achieving anatomical and functional stabilisation in cCSC. The limited visual improvement in Re-PDT and CNV subgroups underscores the importance of early treatment and tailored decision-making in cases of secondary neovascularisation.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"759-766"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corneal Neurotisation in Neurotrophic Keratopathy: A Retrospective Analysis of Functional Outcomes and Clinical Courses. 神经营养性角膜病变的角膜神经化：功能结局和临床过程的回顾性分析。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-25 DOI: 10.1055/a-2864-5774

Patrick Thelen, Jakob B W Weiss, Thomas Reinhard, Wolf Alexander Lagrèze, Steffen U Eisenhardt, Philip Christian Maier

{"title":"Corneal Neurotisation in Neurotrophic Keratopathy: A Retrospective Analysis of Functional Outcomes and Clinical Courses.","authors":"Patrick Thelen, Jakob B W Weiss, Thomas Reinhard, Wolf Alexander Lagrèze, Steffen U Eisenhardt, Philip Christian Maier","doi":"10.1055/a-2864-5774","DOIUrl":"10.1055/a-2864-5774","url":null,"abstract":"Abstract: BACKGROUND: Neurotrophic keratopathy (NK) is a rare, chronic corneal disorder resulting from impaired sensory innervation. Corneal neurotisation, which restores corneal innervation through nerve transfer, has emerged as a promising causal treatment approach. This retrospective study aimed to evaluate the clinical outcomes of corneal neurotisation in patients with NK.Abstract: MATERIAL AND METHODS: We retrospectively reviewed all patients who underwent indirect corneal neurotisation using an autologous sural nerve interposition graft for NK at the Eye Center at Medical Center, University Freiburg. Demographic characteristics, aetiology, postoperative corneal sensitivity, epithelial integrity, visual acuity, and complications were analysed descriptively.Abstract: RESULTS: A total of four patients with Mackie stages 2 to 3 were included in the analysis. All developed measurable corneal sensitivity after surgery, whereas no sensitivity was present preoperatively. Complete corneal epithelialisation was achieved in every case, with no recurrent epithelial defects during follow-up (4 - 49 months). No intraoperative or postoperative complications occurred. All patients reported subjective improvement, including reduced discomfort, keratitis, and recurrent erosions.Abstract: CONCLUSION: Indirect corneal neurotisation using an autologous sural nerve graft appears to be a safe and effective option for treating neurotrophic keratopathy. The procedure can restore corneal sensitivity, promote epithelial healing, and substantially alleviate symptoms, thereby improving patients' overall quality of life.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148330600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Siderotic Cataract Eight Months After Intralenticular Metallic Foreign Body: A Case Report and Surgical Management]. [晶状体内金属异物术后8个月白内障1例及手术处理]。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-22 DOI: 10.1055/a-2879-3759

Anton Sonntag, Daniel Röck, Karl Ulrich Bartz-Schmidt, Tobias Röck

引用次数: 0

Rare Presentation of Hidradenoma Papilliferum in the Caruncle: A Case Report. [卡隆克尔乳头状腺瘤的罕见表现：病例报告]。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-22 DOI: 10.1055/a-2848-8836

Mohamed Elabbasy, Irina Berger, Antonia Hehr, Felix Treumer

引用次数: 0

Impact of Wearing a Face Mask on the Reliability of Standard Automated Perimetry in Glaucoma Patients and Suspects: a Retrospective Longitudinal Study. 戴口罩对青光眼患者和疑似青光眼患者标准自动视野测量可靠性的影响：一项回顾性纵向研究。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-22 DOI: 10.1055/a-2823-2534

Philip Keye, Julien Martin, Charlotte Evers, Daniel Böhringer, Thomas Reinhard, Jan Luebke

{"title":"Impact of Wearing a Face Mask on the Reliability of Standard Automated Perimetry in Glaucoma Patients and Suspects: a Retrospective Longitudinal Study.","authors":"Philip Keye, Julien Martin, Charlotte Evers, Daniel Böhringer, Thomas Reinhard, Jan Luebke","doi":"10.1055/a-2823-2534","DOIUrl":"https://doi.org/10.1055/a-2823-2534","url":null,"abstract":"Abstract: PURPOSE: To assess the reliability of standard automated perimetry in a real-life cohort of glaucoma patients and suspects wearing face masks due to the COVID-19 pandemic in a large German eye hospital.Abstract: METHODS: Data of 160 eyes of 83 glaucoma patients and suspects who received at least one visual field examination and optical coherence tomography for glaucoma monitoring in 2018, 2019 and 2020 were included. Mean visual field defect and the rates of false-positive and false-negative responses between tests without (2019) and tests with a face mask (2020) were compared. Mean retinal nerve fibre layer thickness and the minimum rim width of Bruch's membrane opening served as a control for glaucoma progression.Abstract: RESULTS: No statistically significant difference between visual fields without a face mask, and examinations with a face mask could be detected for mean defect (p = 0.075), rate of false-positives (p = 0.7) and rate of false-negatives (p = 0.16).Abstract: CONCLUSION: Our data suggest that protective face mask wear does not impair the quality and reliability of standard automated perimetry in a real-life cohort of glaucoma patients and glaucoma suspects.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraorbital Abducens Nerve Schwannoma: Clinical Presentation and Histology of a Rare Tumor. [眶内鞘外神经：罕见肿瘤的临床表现与组织学]。

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-19 DOI: 10.1055/a-2834-8118

Charlotte Semoulin, Colya N Englisch, Karl T Boden, Clemens N Rudolph, Ori Staszewski, Gesine Szurman, Peter Szurman, Philip Wakili

引用次数: 0

[Clinical Manifestations of the Axenfeld-Rieger Syndrome in FOXC1-associated Disease]. foxc1相关疾病Axenfeld-Rieger综合征的临床表现

IF 1.1 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2026-06-19 DOI: 10.1055/a-2858-0240

Clara Gruenauer-Kloevekorn, Erika Maka, László Imre, Nagy Zsolt Zoltán, Eszter Jávorszky, Kálmán Tory, Bela Csákány, Nóra Szentmáry

引用次数: 0