Klinische Monatsblatter fur Augenheilkunde最新文献

{"title":"Long-term Follow-up of Outer Retinal Microdefects (ORMDs) in Pachychoroid Pigment Epitheliopathy (PPE) and Subsequent Central Serous Chorioretinopathy (CSCR): A Report of Two Cases.","authors":"Mihaela Chitoroaga, Yannic Pannatier Schuetz, Daniela Gallo Castro, Anna Chiara Nascimbeni, Aude Ambresin","doi":"10.1055/a-2500-5687","DOIUrl":"10.1055/a-2500-5687","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"418-420"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Reproducibility of Measurements of Peripapillary Blood Flow with Laser Speckle Flowgraphy in Healthy and POAG Subjects.","authors":"Alexander von Vopelius-Feldt, Timothy Hamann, Andreas Mayr, Marc Töteberg-Harms","doi":"10.1055/a-2469-8403","DOIUrl":"10.1055/a-2469-8403","url":null,"abstract":"<p><strong>Background: </strong>Peripapillary blood flow is of diagnostic value in glaucoma.</p><p><strong>Material and methods: </strong>We investigated the reproducibility of peripapillary blood flow measurements in healthy individuals and in open-angle glaucoma (OAG) patients with the Nidek laser speckle flowgraphy (LSFG)-NAVI system. Blood flow was calculated as the mean of vascular area (MV), mean of tissue area (MT), and mean of overall flow (MA). Intra-rater, inter-session, and inter-rater reproducibility were assessed by determining the intraclass correlation coefficient (ICC) and coefficient of variance (COV).</p><p><strong>Results: </strong>There were 28 healthy subjects and 16 patients with OAG who participated in this prospective single-center trial. ICC and COV of intra-rater reproducibility were assessed in MV as 0.901; 6.424, MT as 0.909; 4.025, and MA as 0.965; 4.168. Inter-session reproducibility yielded ICC and COV values of MV (0.834; 9.223), MT (0.904; 6.215), MA (0.909; 7.069). Inter-rater reproducibility was computed for MV as 0.78; 9.758, MT as 0.890; 7.210, and MA as 0.888; 6.942. There was a significant difference in MA (p = 0.0184) between the healthy individuals (mean 36.299) and the OAG group (mean 24.944), which was not observed for MV (p = 0.0735) or MT (<i>p = </i>0.1351).</p><p><strong>Conclusion: </strong>High reproducibility of measurements of peripapillary blood flow with the LSFG system was demonstrated in both groups. There is a difference in peripapillary blood flow between healthy controls and OAG patients.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"384-391"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Conventional Horizontal Strabismus Surgery Still a Valid Option in High Myopia?","authors":"Lene Maurer, Anja Palmowski-Wolfe","doi":"10.1055/a-2498-0202","DOIUrl":"10.1055/a-2498-0202","url":null,"abstract":"<p><strong>Background: </strong>Surgical methods to join extraocular muscles are now often used to reduce the risk of scleral perforation in strabismus surgery, but published results indicate that the outcome is highly variable. We therefore wanted to assess whether conventional horizontal strabismus surgery is still a valid option in high myopia.</p><p><strong>Patients and methods: </strong>A retrospective chart review of patients with high myopia, defined as a spherical equivalent of ≥ - 6.0 D in at least one eye, and who had undergone conventional horizontal strabismus surgery was performed. Exotropic angles were converted to positive angles to summarize the results.</p><p><strong>Results: </strong>22 patients were analyzed (15 corrected for esotropia, 7 for exotropia). Prior to surgery, the mean angle of deviation, measured with the alternate prism cover test, was 33.9 prism diopters (PD; range 13 - 75 PD) at distance and 35.3 PD (range 8 - 75 PD) at near. Three months post-surgery, the overall mean dose effect (DE in PD/mm surgery) was 2.8 (standard deviation [SD] 0.5) at distance and 2.9 (SD 0.6) at near. In esotropia, the mean DE was 3.0 at both distance and near; in exotropia, the mean DE was 2.3 at distance and 2.5 at near. There were no major complications such as scleral perforations or retinal detachment.</p><p><strong>Conclusion: </strong>Our data show that conventional horizontal strabismus surgery in high myopia is feasible, is not linked to an increased risk of scleral perforation, and offers predictable results.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"478-480"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Ophthalmology Residency Training in Switzerland: A Trainee-Based Survey.","authors":"Amr Saad, Rino Vicini, Nastasia Foa, Frédéric Villard, Sarah Vez, Anne Catherine Karal-Biechl, Virginie Bühler, Lilly Khamsy, Ferhat Turgut","doi":"10.1055/a-2460-0047","DOIUrl":"10.1055/a-2460-0047","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the current status of ophthalmology residency training in Switzerland and provide insights for enhancing training programs.</p><p><strong>Materials and methods: </strong>The survey covered demographic data such as gender, age, workplace, and year of residency, as well as working conditions, current practical and diagnostic skills, interest in scientific work, and future plans. It consisted of 16 multiple choice questions (MCQ), 5 multiple select questions (MSQ), 8 free-text, 6 Net Promoter Score (NPS), and 4 Likert scale questions. All Young Swiss Ophthalmologists (YSO) members received an invitation to participate in the survey using an online form. All collected data were anonymized, and participants provided their consent for data collection, analysis, and publication.</p><p><strong>Results: </strong>The survey assessed the perspectives of 63 Swiss ophthalmology residents on their training experiences. Respondents indicated the greatest interest in specializing in cataract and vitreoretinal surgery, followed by cornea, glaucoma, refractive surgery, and lid surgery. They also expressed a great need for improved supervision, structured curricula, and alignment of clinical and research duties. While pursuing additional surgical training and private practice autonomy, residents also expressed a preference for balanced workloads that emphasize patient care over full-time academic work.</p><p><strong>Conclusion: </strong>The survey indicates a need to standardize ophthalmology residency training in Switzerland to ensure comprehensive and uniform education. It also highlights specific areas for improvement, such as the absence of surgical training. Ongoing assessments are necessary to evaluate future developments.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"498-506"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperreflective Dots (HRDs) in Two Patients with Nonarteritic Anterior Ischemic Optic Neuropathy (NAION).","authors":"Elisa Santos, Peter M Maloca, Aki Kawasaki","doi":"10.1055/a-2532-1032","DOIUrl":"https://doi.org/10.1055/a-2532-1032","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"242 4","pages":"471-474"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Ocular Biometry Measurements from Two Swept-Source OCT Devices: Eyestar 900 vs. Anterion.","authors":"Julian V Kool van Langenberghe, Petra Schwarzer, Tobias Jahn, Christoph Tappeiner, Dimitrios Kyroudis, Eva Vrbka, David Goldblum","doi":"10.1055/a-2463-4061","DOIUrl":"10.1055/a-2463-4061","url":null,"abstract":"<p><strong>Background: </strong>Advanced swept-source optical coherence tomography (SS-OCT) devices are the current gold standard for the measurement of ocular biometric and keratometric parameters, which are essential for the calculation and selection of intraocular lenses (IOLs). This study compares the agreement of two SS-OCT devices, the Eyestar 900 (Haag-Streit, Köniz, Switzerland) and the Anterion (Heidelberg Engineering, Heidelberg, Germany).</p><p><strong>Materials and methods: </strong>All patients undergoing cataract surgery or seeking consultation for corneal abnormalities between January 2024 and May 2024 were eligible for inclusion. Both eyes were included in the final analysis.</p><p><strong>Results: </strong>A sample of 86 eyes from 43 patients was analysed. The mean differences (ES-AN) across all data between the Eyestar 900 (ES) and Anterion (AN) were as follows: anterior chamber depth (ACD) - 0.080 mm (ICC > 0.926), axial length (AL) 0.015 mm (ICC > 0.99), central corneal thickness (CCT) 0.914 µm (ICC > 0.921), corneal curvature along the flat meridian (K1) - 0.024 D (ICC > 0.904), and steep meridian (K2) - 0.210 D (ICC > 0.902), white-to-white corneal diameter (WTW) 0.215 mm (ICC > 0.81). There was excellent agreement for ACD, AL, CCT, K1, K2, and WTW. However, the corneal axis (AX) showed only moderate agreement (ICC > 0.389), with a mean difference of 5.97° and a notable standard deviation of 58.6°.</p><p><strong>Conclusions: </strong>The Eyestar 900 and Anterion demonstrated substantial agreement for all parameters except for the corneal meridian axis. It may be assumed that the inclusion of eyes with irregular corneal topographies may have contributed to this discrepancy.</p><p><strong>Summary: </strong>Overall, there was a high level of agreement between the Eyestar 900 and Anterion. It is reasonable to assume that the measurement outcomes provided by both devices are interchangeable for the calculation of target refractive outcomes for intraocular lenses, with no clinically relevant differences.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"357-362"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Eye injuries and defective vision in school and club sports - Arguments for DIN-approved glasses suitable for school sports].","authors":"Gernot Jendrusch","doi":"10.1055/a-2288-3021","DOIUrl":"10.1055/a-2288-3021","url":null,"abstract":"<p><p>Visual deficits/ametropia are particularly significant obstacles in sports because the visual system controls/corrects all of an athlete's movements. However, athletes are at increased risk for eye injuries caused by high-velocity objects e.g. balls or physical contact with opponents. This article presents the current (German) figures on eye injuries in club and school sports and evaluates the risk of eye injuries in various sports.2392 eye injuries, selected from the 221273 club sports injuries recorded in the Ruhr University Bochum and ARAG Sports Insurance database for the period 1987-2017 were evaluated. The school sports eye injuries recorded by the German Social Accident Insurance for 2019 were also analyzed.Of all the club sports injuries recorded, 1.08% were eye injuries; of these, 19.7% had to be treated in hospital, 13.9% required surgery, and 56.9% prevented the injured athletes from working. Blunt trauma was the most common cause of injury, comprising more than 50% of cases. Eye injuries were strongly overrepresented in club sports injuries sustained during water polo, squash, badminton, and tennis (injury proportion ratio [IPR] = 5.1-8.8). In school sports, eye injuries comprised 1.83% of the reported cases.Eye injuries in sports are relatively rare, but often serious. Based on the increased IPR found for some sports, further studies must analyze the risk of eye injury in more detail. Eye protection in the form of sport-appropriate glasses should be used.In addition, the article addresses the problem of \"defective vision in sport\" and its adequate correction and shows the requirements for spectacles suitable for (school) sport using the example of DIN 58184 \"Spectacles suitable for school sports - Requirements and test methods\".</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"521-531"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Analytical Methods for the Validation of the Sterility of Autologous Serum Eye Drops.","authors":"Frank Blaser, Isabelle Meneau, Jana Schneider, Jürg Wiedler, Hanspeter Hinrikson, Daniel Barthelmes, Sandrine Zweifel, Anahita Bajka, Sadiq Said, Maximilian Robert Justus Wiest","doi":"10.1055/a-2468-5416","DOIUrl":"10.1055/a-2468-5416","url":null,"abstract":"<p><strong>Purpose: </strong>For specific samples, there are different methods and requirements for testing sterility. Blood and blood products are analyzed using automated blood culture methods, while pharmacopeial sterility is assessed using membrane filtration or direct inoculation according to the European Pharmacopoeia (Ph. Eur. 2.6.1.) to detect microbial growth. As autologous serum eye drops (ASEDs) may be viewed as both a blood product and a classical drug, the Swiss legislator has classified these as non-standardizable drugs, and thus, the pharmacopeial requirements apply. This study investigates ASED preparations with respect to the performance of a common automated blood culture system, BD BACTEC, in detecting aerobic and anaerobic bacteria and fungi in ASED preparations, with pharmacopeial sterility testing using agar plate cultures.</p><p><strong>Methods: </strong>Based on the European Pharmacopoeia, we inoculated sterile filtered blood serum with BioBalls of the six reference strains at a low concentration of three colony-forming units per milliliter (CFU/mL). A test battery of three different BD BACTEC culture media (hereafter referred to as Trio-BACTEC : BD BACTEC Plus Aerobic/F-Medium, BD BACTEC Lytic/10 Anaerobic/F-Medium, BD BACTEC Mycosis IC/F-Medium) and three agar plates [Tryptic Soy Agar (TSA), Chocolate Blood Agar, Sabouraud's Dextrose Agar] were inoculated per strain. We incubated the Trio- BACTEC in the BD BACTEC Blood Culture System at 35 °C for 5 days, the TSA and Chocolate plates at 35 °C for 5 days, and the Sabouraud plates at 25 °C for 7 days. We confirmed positive growth signals by microscopy or MALDI-ToF mass spectrometry and included negative controls.</p><p><strong>Results: </strong>We detected all reference strains using BACTEC and agar plates. No growth was observed in the negative controls. Overall, growth detection by BACTEC and agar plates was comparable, except for <i>Aspergillus brasiliensis</i> and <i>Candida albicans</i>, which was detected after 1 day on solid media and after 2 days on BACTEC.</p><p><strong>Conclusion: </strong>This study demonstrates the comparability of sensitivity and detection speed using the automated blood culture method and agar plates for sterility validation of ASED, even at low bacterial and fungal contamination levels.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"298-303"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-Onset Focal Corneal Edema and Recurrent Uveitis Anterior due to Retained Lens Fragment after Uneventful Cataract Surgery.","authors":"Eleftherios Chatzimichail, Alexandra Steinemann-Inauen, Oussama Habra, Peter Meyer, Nicolas Feltgen, Zisis Gatzioufas","doi":"10.1055/a-2463-0967","DOIUrl":"10.1055/a-2463-0967","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"461-462"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Choroidal Neovascularization in Pediatric Uveitis: A Case Series.","authors":"Amandine Gauderon, Chiara Eandi, Aikaterini Koryllou, Florence Hoogewoud, Katerina Theodoropoulou, Yan Guex-Crosier","doi":"10.1055/a-2467-1804","DOIUrl":"10.1055/a-2467-1804","url":null,"abstract":"<p><strong>Background: </strong>The aim of our study is to describe clinical features, therapy, and outcome of children with inflammatory choroidal neovascularization (CNV).</p><p><strong>Methods: </strong>Retrospective case series of children seen at the Jules-Gonin Eye Hospital between 2000 and 2024 with macular choroidal neovascularisation secondary to ocular inflammation.</p><p><strong>Results: </strong>Four children (one male, three females) developed a retro-foveolar neovascular membrane after a median time of 2.5 months (range 1 - 16 months) following uveitis onset. The median age at presentation was 12 years (range 5 - 12 years). The CNV presentation was unilateral in all four cases, with three patients having posterior uveitis and one panuveitis. Two patients had idiopathic bilateral granulomatous uveitis while the other two had suspected toxoplasmosis chorioretinitis. Idiopathic cases were treated with oral steroids, with one patient being additionally treated with adalimumab. Toxoplasmosis cases were managed with antibiotics and oral steroids. CNV treatment involved a single anti-VEGF injection in two cases, six injections in one case, and no injection in one case due to CNV inactivity. Median follow-up period was 4.25 years (range 0.75 to 11 years) and the median final best-corrected visual acuity was 0.9 (range 0.6 - 1.25). No recurrence of CNV was observed, despite uveitis reactivation in two cases.</p><p><strong>Conclusion: </strong>Anti-VEGF therapy is safe even in young children with minimal injections required to control the disease. Treating the underlying cause of uveitis with appropriate therapy is also crucial.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":"466-470"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}