Korean Journal of Ophthalmology : KJO最新文献

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Comments on "The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects". 对“健康受试者乳头周围和乳头旁脉络膜厚度的相关性”的评论。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-04-01 DOI: 10.3341/kjo.2022.0124
Salih Uzun, Fatma Uzun
{"title":"Comments on \"The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects\".","authors":"Salih Uzun, Fatma Uzun","doi":"10.3341/kjo.2022.0124","DOIUrl":"https://doi.org/10.3341/kjo.2022.0124","url":null,"abstract":"Dear Editor, We have read and reviewed the article entitled “The correlation of peripapillary and juxtapapillary choroidal thickness in healthy subjects” by Son et al. [1] with great interest. The authors investigated the peripapillary choroidal thickness (PPCT) and juxtapapillary choroidal thickness (JPCT) by using circle and radial B-scan images, respectively. The authors showed that the two measures of choroidal thickness (CT) around the optic nerve head were well correlated. However, the peripapillary choroid was generally thicker than the juxtapapillary choroid, especially in eyes with small Bruch’s membrane opening area. We congratulate the authors for their precious study, and we would like to request more details and their valuable contributions to the article. The choroid is one of the most vascularized regions of the human body. Therefore, various local and systemic physiologic/pathologic conditions and environmental factors have effects on CT. It has been shown in the literature that age, sex, systemic or local diseases and their treatments, use of medicine, intraocular pressure, refractive error, axial length of the globe, and many other factors have effects on CT [2]. In addition, pregnancy, body mass index, menstrual cycle, and systemic blood pressure have a remarkable effect on CT. Furthermore, consuming food, and caffeinated or noncaffeinated drinks, and exercise before optical coherence tomography measurements can cause significant changes in CT [2]. Moreover, CT shows considerable diurnal variation and is able to increase by 50% in an hour and by four times in a few days [3]. We would like to ask authors whether all those factors have been assessed in the study.","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 2","pages":"198-199"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/79/86/kjo-2022-0124.PMC10151172.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10213446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Reply: Comments on "The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects". 作者回复:对“健康受试者乳头周围和乳头旁脉络膜厚度的相关性”的评论。
Dong Hwan Son, Jinho Lee, Jeong-Ah Kim
{"title":"Author Reply: Comments on \"The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects\".","authors":"Dong Hwan Son, Jinho Lee, Jeong-Ah Kim","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 2","pages":"198-199"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10154674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Fractal Dimension of Peripapillary Vasculature in Primary Open-Angle Glaucoma 原发性开角型青光眼乳头周围血管分形维数的修正
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-21 DOI: 10.3341/kjo.2020.0089.e1
Chae Hyun Song, S. Kim, K. Lee
{"title":"Correction to: Fractal Dimension of Peripapillary Vasculature in Primary Open-Angle Glaucoma","authors":"Chae Hyun Song, S. Kim, K. Lee","doi":"10.3341/kjo.2020.0089.e1","DOIUrl":"https://doi.org/10.3341/kjo.2020.0089.e1","url":null,"abstract":"","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"13 1","pages":"200 - 200"},"PeriodicalIF":0.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73137017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Visual Acuity, Macular Thickness, and Level of Proteinuria in Children with Nephrotic Syndrome. 肾病综合征儿童的视力、黄斑厚度和蛋白尿水平的评价。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2021.0131
Lam Mun-Wei, Mohd Yazid Aiman-Mardhiyyah, Abdul Aziz Hayati, Ilias Mohamad Ikram, Evelyn Li Min Tai, Ismail Shatriah
{"title":"Evaluation of Visual Acuity, Macular Thickness, and Level of Proteinuria in Children with Nephrotic Syndrome.","authors":"Lam Mun-Wei,&nbsp;Mohd Yazid Aiman-Mardhiyyah,&nbsp;Abdul Aziz Hayati,&nbsp;Ilias Mohamad Ikram,&nbsp;Evelyn Li Min Tai,&nbsp;Ismail Shatriah","doi":"10.3341/kjo.2021.0131","DOIUrl":"https://doi.org/10.3341/kjo.2021.0131","url":null,"abstract":"<p><strong>Purpose: </strong>Macular edema, serous retinal detachment, and retinal pigment epithelial detachment have been reported in patients with nephrotic syndrome. However, there is limited data about macular thickness in children with nephrotic syndrome. The aim of this study was to compare the mean macular thickness in children with nephrotic syndrome and in a control group and to correlate it with visual acuity and level of proteinuria.</p><p><strong>Methods: </strong>The comparative cross-sectional study included 66 children aged 6 to 17 years with nephrotic syndrome and healthy control seen in two tertiary centers in Malaysia. We recorded demographic data, as well as visual acuity, level of proteinuria, and the mean macular thicknesses in both groups. The mean macular thickness was measured using Stratus optical coherence tomography according to nine areas of the Early Treatment Diabetic Retinopathy Study map.</p><p><strong>Results: </strong>The mean foveal thickness was 238.15 ± 22.98 µm for children with nephrotic syndrome and 237.01 ± 22.60 µm for the control group. There was no significant difference in the mean macular thickness between the groups (p = 0.843). A significant correlation with visual acuity was observed in the superior outer macula (r = -0.41, p = 0.019), the nasal outer macula (r = -0.41, p = 0.019), and the inferior outer macula (r = -0.40, p = 0.021). There was no significant correlation between the mean macular thickness and level of proteinuria (p = 0.338), although those with higher levels of proteinuria demonstrated a trend towards increased macular thickness.</p><p><strong>Conclusions: </strong>The mean macular thickness in children with nephrotic syndrome was similar to that of healthy children. A significant correlation between the mean thickness of the outer macular layer and the presenting visual acuity was observed. There was no correlation between the mean macular thickness and the level of proteinuria.</p>","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"42-48"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/9d/kjo-2021-0131.PMC9935067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9156516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Gonococcal Conjunctivitis in Adolescent Teenager: A Case Report. 青少年急性淋球菌性结膜炎1例报告。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0158
Seung Hee Ha, Hui Kyung Kim, Yeon Ji Jo
{"title":"Acute Gonococcal Conjunctivitis in Adolescent Teenager: A Case Report.","authors":"Seung Hee Ha,&nbsp;Hui Kyung Kim,&nbsp;Yeon Ji Jo","doi":"10.3341/kjo.2022.0158","DOIUrl":"https://doi.org/10.3341/kjo.2022.0158","url":null,"abstract":"Dear Editor, Gonococcal conjunctivitis is typically a neonatal disease. However, the incidence of gonococcal conjunctivitis in adults is increasing because of the increased frequency of urogenital gonococcal infections [1]. Most cases occur in neonates or sexually active adults. It is rarely considered in older children or adolescents. Since it is relatively rare in adolescents, clinical diagnosis may be delayed [2,3]. Inappropriate treatment timing means that gonococcal conjunctivitis could progress in a rapid and fulminant fashion, threatening patients’ vision. If systemic antibiotic therapy and topical eye-drop treatment are instituted before severe corneal complications occur, serious sequelae and visual loss could be reduced. We report a rare case of acute gonococcal conjunctivitis in an adolescent teenager diagnosed using a bacterial culture test without any ocular complications. The patient provided informed consent for the publication of clinical photographs. A 13-year-old adolescent boy presented with severe eyelid swelling and ocular pain with purulent discharge from the left eye, which started 5 days before presentation. The best-corrected visual acuity (BCVA) of the right eye was 20 / 20 and that of the left eye was 20 / 400. Severely decreased visual acuity of the left eye was observed. Slitlamp examination revealed unremarkable findings in the right eye; however, the left eye showed severe chemosis with conjunctival injection, vessel dilatation, and multiple tarsal conjunctival follicles. Diffuse superficial punctate corneal lesions with hazy and mild edema and purulent discharge in the conjunctival sac were also observed (Fig. 1A, 1B). The patient denied a history of sexual contact and showed no evidence of genitourinary symptoms. However, because gonococcal conjunctivitis was strongly suspected, bacterial culture using a disinfectant swab was performed at the first visit, and other laboratory examinations and urine analyses were performed. This patient, with gram-negative intracellular diplococci on Gram stain, subsequently had positive conjunctival cultures for Neisseria gonorrhoeae. Other blood markers of inf lammation, such as C-reactive protein and erythrocyte sedimentation rate, were slightly elevated, but urinalysis results were normal. The patient was administered a single dose of 1 g of intravenous ceftazidime (Cefazim, HK inno.N) and 500 mg azithromycin (Zithromax, Pfizer Inc) orally twice a day for 5 days. Topical fortified tobramycin and cephalosporin eye drops were instilled every 1 hour. Within a day, the patient showed reduced ocular discharge and inflamed conjunctiva (Fig. 1C, 1D). Topical fortified eyedrops were tapered and used every 2 hours. After 5 days, the BCVA of the left eye was 20 / 50, and conjunctival injection and corneal haziness improved (Fig. 1E, 1F). The patient was discharged after 5 days of treatment. Topical fortified eyedrops were used four times a day. After 2 weeks, the left eye BCVA was 20 / 2","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"91-92"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8d/cd/kjo-2022-0158.PMC9935068.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9218189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Y-27632, a Rho-associated Kinase Inhibitor, on Human Corneal Endothelial Cells Cultured by Isolating Human Corneal Endothelial Progenitor Cells. rho相关激酶抑制剂Y-27632对分离培养的人角膜内皮祖细胞的影响
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0133
Haeeun Shin, Joon Ki Min, Na Rae Kim, Kyoung Yul Seo, Hee Seung Chin, Soyoung Lee, Ji Won Jung
{"title":"Effects of Y-27632, a Rho-associated Kinase Inhibitor, on Human Corneal Endothelial Cells Cultured by Isolating Human Corneal Endothelial Progenitor Cells.","authors":"Haeeun Shin,&nbsp;Joon Ki Min,&nbsp;Na Rae Kim,&nbsp;Kyoung Yul Seo,&nbsp;Hee Seung Chin,&nbsp;Soyoung Lee,&nbsp;Ji Won Jung","doi":"10.3341/kjo.2022.0133","DOIUrl":"https://doi.org/10.3341/kjo.2022.0133","url":null,"abstract":"<p><strong>Conclusions: </strong>Y-27632 enabled the isolation and expansion of HCEPs. It also enhanced the proliferation, viability, and migration of differentiated HCEPs.</p><p><strong>Methods: </strong>HCEPs were isolated and expanded in a medium with and without 10μM Y-27632, and then differentiated into HCECs in a medium with fetal bovine serum. The characteristics of HCEPs and differentiated HCEPs were confirmed by immunofluorescence staining. The proliferation, viability, morphology, and wound-healing ability of differentiated HCEPs were assessed in the presence of different concentrations of Y-27632.</p><p><strong>Purpose: </strong>Human corneal endothelial progenitor cells (HCEPs), which has been selectively isolated and differentiated into human corneal endothelial cells (HCECs), are crucial for repairing corneal endothelial damage. In this study, we evaluated the roles of a Rho-assisted kinase (ROCK) inhibitor, Y-27632, on the isolation and expansion of HCEPs, and assessed the in vitro effects of different concentrations of Y-27632 on the differentiated HCEPs.</p><p><strong>Results: </strong>Y-27632 enabled the isolation and expansion of HCEPs from the corneal endothelium. The differentiated HCEPs showed an optimal increase in proliferation and survival in the presence of 10μM Y-27632. As the concentration of Y-27632 increased, differentiated HCEPs became elongated, and actin filaments were redistributed to the periphery of cells. Y-27632 also caused a concentration-dependent enhancement in the wound-healing ability of differentiated HCEPs.</p>","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"31-41"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/7c/kjo-2022-0133.PMC9935058.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9156517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of Involutional Entropion by Excising Redundant Skin and Pretarsal Orbicularis Muscle without Vertical and Horizontal Tarsal Fixation. 无垂直和水平跗骨固定,切除多余皮肤和睑前轮匝肌矫正睑内翻。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0138
Eun Woo Choi, Sun Young Jang
{"title":"Correction of Involutional Entropion by Excising Redundant Skin and Pretarsal Orbicularis Muscle without Vertical and Horizontal Tarsal Fixation.","authors":"Eun Woo Choi,&nbsp;Sun Young Jang","doi":"10.3341/kjo.2022.0138","DOIUrl":"https://doi.org/10.3341/kjo.2022.0138","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the effect of the excision of redundant skin and pretarsal orbicularis muscle, without vertical or horizontal tarsal fixation, on the correction of involutional entropion.</p><p><strong>Methods: </strong>This retrospective interventional case series recruited patients with involutional entropion who underwent excision of redundant skin and pretarsal orbicularis muscle, without vertical or horizontal tarsal fixation, from May 2018 to December 2021. Preoperative clinical characteristics and surgical outcomes, including recurrence at 1, 3, and 6 months, were determined by reviewing the medical charts. Surgical treatment included the excision of redundant skin and pretarsal orbicularis muscle, without any tarsal fixation, and simple skin suture.</p><p><strong>Results: </strong>All 52 patients (58 eyelids) attended every follow-up visit and were thus included in the analysis. Among 58 eyelids, 55 (94.8%) had satisfactory results. The recurrence rate was 3.45% (two eyelids) and the overcorrection rate was 1.7% (one eyelid).</p><p><strong>Conclusions: </strong>Excision of only redundant skin and the pretarsal orbicularis muscle, without capsulopalpebral fascia reattachment or horizontal lid laxity correction, is a simple surgery for correcting involutional entropion.</p>","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"49-52"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/cb/kjo-2022-0138.PMC9935069.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9218192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Risk Factors Affecting Refractive Outcomes after Phacovitrectomy for Epiretinal Membrane. 影响晶状体切除术后视网膜前膜屈光效果的危险因素评估。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0108
Yu Jin Roh, Joo Young Shin, Tae Wan Kim, Jeeyun Ahn
{"title":"Assessment of Risk Factors Affecting Refractive Outcomes after Phacovitrectomy for Epiretinal Membrane.","authors":"Yu Jin Roh,&nbsp;Joo Young Shin,&nbsp;Tae Wan Kim,&nbsp;Jeeyun Ahn","doi":"10.3341/kjo.2022.0108","DOIUrl":"https://doi.org/10.3341/kjo.2022.0108","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate factors associated with refractive outcomes after phacovitrectomy for epiretinal membrane (ERM).</p><p><strong>Methods: </strong>Retrospective review of patients undergoing phacovitrectomy for ERM was done. The main outcome measure was predictive refraction error (PE), defined as observed refraction error - target refraction error, calculated by the SRK/T, Haigis, and SRK II formulae. PE was measured at postoperative 1, 3, and 6 months. Simple and multiple linear regression analysis were used to evaluate factors associated with PE.</p><p><strong>Results: </strong>A total of 53 eyes of 53 patients were included. The mean PEs at postoperative 1, 3, and 6 months were all negative, implying myopic shift in all patients regardless of the intraocular lens formula used. Haigis formula showed the least myopic shift among the three formulae (p = 0.001, Friedman test). There was no significant difference in PE depending on preoperative central macular thickness (CMT) in subgroup analysis. On stepwise multiple linear regression analysis, ERM etiology (β = 0.759, p = 0.004, SRK/T formula; β = 0.733, p = 0.008, Haigis formula; β = 0.933, p < 0.001, SRK II formula), preoperative anterior chamber depth (β = -0.662, p = 0.013, Haigis formula; β = -0.747, p = 0.003, SRK II formula), and decrease of CMT (β = -0.003, p = 0.025, SRK/T formula) were significantly associated with PE at postoperative 6 months.</p><p><strong>Conclusions: </strong>Myopic shift in PE was observed after combined phacovitrectomy for epiretinal membrane. ERM etiology, preoperative anterior chamber depth, and decrease of CMT were significantly associated with PE at postoperative 6 months. There was no difference in PE after surgery between the two groups defined by CMT (≥500 and <500 μm).</p>","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"23-30"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/ad/kjo-2022-0108.PMC9935063.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9156518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Radiation Retinopathy after Heavy Ion Particle Therapy for Maxillary Sinus Cancer: A Case Report. 上颌窦癌重离子粒子放射治疗后视网膜病变1例报告。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0119
Choong Man Choi, Se Joon Woo
{"title":"Radiation Retinopathy after Heavy Ion Particle Therapy for Maxillary Sinus Cancer: A Case Report.","authors":"Choong Man Choi,&nbsp;Se Joon Woo","doi":"10.3341/kjo.2022.0119","DOIUrl":"https://doi.org/10.3341/kjo.2022.0119","url":null,"abstract":"Dear Editor, Radiation retinopathy (RR) is a delayed obstructive microvascular retinopathy that usually develops months to years after radiation therapy and has characteristic findings, such as intraretinal hemorrhage, cotton wool patches, and capillary nonperfusion. Heavy ion particle therapy (HIPT) has emerged as a new technology owing to its safety. Currently, few cases of RR after HIPT have been reported in Japan [1]. Here, we report the first case of RR after HIPT in South Korea. This report was approved by the Institutional Review Board of Seoul National University Bundang Hospital (No. B-2208-774-706) and the patient provided written informed consent for publication of this case report. A 37-year-old male patient visited the clinic for evaluation of his eye 1 month after receiving a total dose of 70.4 Gy carbon HIPT over 16 fractions in an area that included the optic nerve for undifferentiated polymorphic sarcoma in the right maxillary sinus. Brain and orbital magnetic resonance imaging (MRI) revealed that the tumor was in contact with the medial and inferior rectus muscles but did not invade the eyeball or optic nerve. Dendritic cell-based cancer vaccine treatment was concurrently combined with HIPT. Corrected visual acuity of 20 / 16 in the right eye was measured, and no abnormalities were found in the anterior segment and fundus. After 23 months of HIPT, the corrected visual acuity was 20 / 125 in the right eye. Relative afferent pupillary defect and optic disc pallor were present in the right eye. Although atrophy or inflammation of the optic nerve was not confirmed by MRI, circumferential peripheral visual field defect was present. These were signs of optic neuropathy. Fluorescein angiography and optical coherence tomography (OCT) angiography were performed. There was no retinal neovascularization, but extensive nonperfusion of the peripheral retina including the macular area with multiple intraretinal hemorrhages and cotton wool patches was observed in the right eye (Fig. 1A–1D). Since the choroidal and retinal perfusion times were within normal range, diseases that induce perfusion abnormalities, such as retinal artery occlusion or ocular ischemic syndrome were excluded. Panretinal photocoagulation was performed to prevent neovascular complications. After 33 months of HIPT, the visual-evoked potential revealed decreased P100 amplitude in the right eye which could be explained by both RR and radiation optic neuropathy. Panretinal photocoagulation was additionally performed because of iris neovascularization. After 3 months, the intraocular pressure increased to 24 mmHg with worsening of iris neovascularization in the right eye. Under the diagnosis of neovascular glaucoma, the intraocular pressure-lowering drugs were prescribed. Additionally, intravitreal bevacizumab (Avastin, Roche) was administered to the right eye five times every few months. After 59 months of HIPT, cataract surgery was performed in the right eye for an intumesce","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"88-90"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/f1/kjo-2022-0119.PMC9935066.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9163500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Cataract on Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Thickness on Swept Source Optical Coherence Tomography. 扫描源光学相干断层扫描中白内障对视网膜神经纤维层和神经节细胞-内丛状层厚度的影响。
Korean Journal of Ophthalmology : KJO Pub Date : 2023-02-01 DOI: 10.3341/kjo.2022.0097
Young-Je Choi, Bo Ram Seol
{"title":"Effects of Cataract on Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Thickness on Swept Source Optical Coherence Tomography.","authors":"Young-Je Choi,&nbsp;Bo Ram Seol","doi":"10.3341/kjo.2022.0097","DOIUrl":"https://doi.org/10.3341/kjo.2022.0097","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the changes in peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGC-IPL) thickness measured by swept source optical coherence tomography (SS-OCT) following cataract surgery in patients with glaucoma.</p><p><strong>Methods: </strong>We included 42 glaucoma eyes and 42 case-matched normal eyes that underwent cataract surgery without complications. One matching set included one glaucoma eye and one case-matched normal eye. The age, sex, and cataract subtype scores were similar for each group. Before and within 3 months of surgery, we measured the pRNFL thickness and mGCIPL thickness by SS-OCT.</p><p><strong>Results: </strong>Following cataract surgery, the image quality (IQ) of SS-OCT improved in both groups. The thickness of the pRNFL and mGC-IPL increased in the mean values and all areas, except for pRNFL from 1 to 4 o'clock in the glaucoma group and at 1 o'clock in the normal group. Posterior subcapsular cataract was related to the change in IQ following surgery. The glaucoma and normal group showed greater pRNFL thickness change due to lesser preoperative pRNFL thickness. Furthermore, the mGC-IPL thickness change was greater in the glaucoma group because of lesser preoperative mGC-IPL thickness. By contrast, the normal group demonstrated greater mGC-IPL thickness change due to higher cortical cataract scores.</p><p><strong>Conclusions: </strong>Cataracts caused the deterioration of the IQ in SS-OCT, thereby resulting in an undermeasurement of the pRNFL and mGC-IPL thickness. Preoperative pRNFL and mGC-IPL were negatively associated with postoperative pRNFL and mGCIPL thickness change in the glaucoma and normal groups. Therefore, ophthalmologists should particularly consider the effect of cataract while diagnosing glaucoma using SS-OCT.</p>","PeriodicalId":17883,"journal":{"name":"Korean Journal of Ophthalmology : KJO","volume":"37 1","pages":"12-22"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/e5/kjo-2022-0097.PMC9935059.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9216704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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