Korean Journal of Anesthesiology最新文献_第5页

Effect of lipid emulsion on vasoconstriction induced by epinephrine or norepinephrine in isolated rat aorta. 脂质乳液对离体大鼠主动脉由肾上腺素或去甲肾上腺素引起的血管收缩的影响

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-06-25 DOI: 10.4097/kja.24093

Soo Hee Lee, Kyeong-Eon Park, Kibaek Eum, Yeran Hwang, Seong-Ho Ok, Gyujin Sim, Dumidu Perera, Henri K M Ravald, Youngho Park, Susanne K Wiedmer, Ju-Tae Sohn

{"title":"Effect of lipid emulsion on vasoconstriction induced by epinephrine or norepinephrine in isolated rat aorta.","authors":"Soo Hee Lee, Kyeong-Eon Park, Kibaek Eum, Yeran Hwang, Seong-Ho Ok, Gyujin Sim, Dumidu Perera, Henri K M Ravald, Youngho Park, Susanne K Wiedmer, Ju-Tae Sohn","doi":"10.4097/kja.24093","DOIUrl":"10.4097/kja.24093","url":null,"abstract":"Background: Epinephrine (EPI) or norepinephrine (NOR) is widely used to treat cardiovascular collapse during lipid emulsion (LE) resuscitation for drug toxicity. However, the effect of LE on the vasoconstriction caused by EPI or NOR remains unknown. The purpose of this study was to examine the effect of an LE (Intralipid) on the vasoconstriction caused by EPI and NOR in isolated rat aorta.Methods: The effect of LE on the vasoconstriction caused by EPI or NOR in isolated rat aorta was examined. Additionally, the effect of LE on the calcium increase caused by EPI or NOR was investigated. The distribution constant (KD: lipid to aqueous phase) of EPI or NOR between a LE (1%) and an aqueous phase was determined.Results: LE (1 and 2%) did not significantly alter vasoconstriction caused by EPI or NOR in isolated endothelium-intact aorta. Moreover, the LE did not significantly alter the increased calcium level caused by EPI or NOR. The log KD of EPI in the LE (1%) was -0.71, -0.99, and -1.00 at 20, 50, and 100 mM ionic strength, respectively. The log KD of NOR in the LE (1%) was -1.22, -1.25, and -0.96 at 20, 50, and 100 mM ionic strength, respectively.Conclusions: Taken together, the Intralipid emulsion did not alter vasoconstriction induced by EPI or NOR that seems to be due to the hydrophilicity of EPI or NOR, leading to sustained hemodynamic support produced by EPI or NOR used during LE resuscitation.","PeriodicalId":17855,"journal":{"name":"Korean Journal of Anesthesiology","volume":" ","pages":"555-564"},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new treatment option for chronic refractory coccygodynia: ultrasound-guided sacral erector spinae plane block. 慢性难治性尾骨痛的新治疗方案：超声引导下的骶骨竖脊肌平面阻滞。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-07-18 DOI: 10.4097/kja.24226

Tuba Tanyel Saraçoğlu, Burak Erken, Ergün Mendeş

引用次数: 0

Comment on "Retro superior costotransverse ligament space block as an effective analgesia after laparoscopic gastrectomy". 上肋横韧带后间隙阻滞是另一种横突间阻滞。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-07-12 DOI: 10.4097/kja.24283

Raghuraman M Sethuraman

引用次数: 0

Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study. 经导管主动脉瓣置换术后在监测麻醉护理下使用雷马唑仑与右美托咪定对恢复的影响：倾向得分匹配、非劣效性研究。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.4097/kja.24138

Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, Wook-Jong Kim, Dae-Kee Choi, In-Cheol Choi

{"title":"Effects of remimazolam versus dexmedetomidine on recovery after transcatheter aortic valve replacement under monitored anesthesia care: a propensity score-matched, non-inferiority study.","authors":"Ji-Hyeon Kim, Jae-Sik Nam, Wan-Woo Seo, Kyung-Woon Joung, Ji-Hyun Chin, Wook-Jong Kim, Dae-Kee Choi, In-Cheol Choi","doi":"10.4097/kja.24138","DOIUrl":"10.4097/kja.24138","url":null,"abstract":"Background: Minimalist transcatheter aortic valve replacement (TAVR) under monitored anesthesia care (MAC) emphasizes early recovery. Remimazolam is a novel benzodiazepine with a short recovery time. This study hypothesized that remimazolam is non-inferior to dexmedetomidine in terms of recovery after TAVR.Methods: In this retrospective observational study, remimazolam was compared to dexmedetomidine in patients who underwent TAVR under MAC at a tertiary academic hospital between July 2020 and July 2022. The primary outcome was timely recovery after TAVR, defined as discharge from the intensive care unit within the first day following the procedure. Propensity score matching was used to compare timely recovery between remimazolam and dexmedetomidine, applying a non-inferiority margin of -10%.Results: The study included 464 patients, of whom 218 received remimazolam and 246 received dexmedetomidine. After propensity score matching, 164 patients in each group were included in the analysis. Regarding timely recovery after TAVR, remimazolam was non-inferior to dexmedetomidine (152 of 164 [92.7%] in the remimazolam group versus 153 of 164 [93.3%] in the dexmedetomidine group, risk difference [95% CI]: -0.6% [-6.7%, 5.5%]). The use of remimazolam was associated with fewer postoperative vasopressors/inotropes (21 of 164 [12.8%] vs. 39 of 164 [23.8%]) and temporary pacemakers (TPMs) (76 of 164 [46.3%] vs. 108 of 164 [65.9%]) compared to dexmedetomidine.Conclusions: In patients undergoing TAVR under MAC, remimazolam was non-inferior to dexmedetomidine in terms of timely recovery. Remimazolam may be associated with better postoperative recovery profiles, including a lesser need for vasopressors/inotropes and TPMs.","PeriodicalId":17855,"journal":{"name":"Korean Journal of Anesthesiology","volume":" ","pages":"537-545"},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric sedation and monitored anesthesia care: from chloral hydrate to remimazolam. 小儿镇静和监测麻醉护理：从水合氯醛到瑞咪唑仑。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI: 10.4097/kja.24632

Won-Jung Shin

引用次数: 0

Ramped versus sniffing position for Ambu® AuraGainTM insertion in patients with obesity: a randomized controlled study. 在肥胖症患者中插入 Ambu® AuraGain™ 时采用斜坡体位还是嗅觉体位：随机对照研究。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-10-01 Epub Date: 2024-08-19 DOI: 10.4097/kja.24255

Hye-Won Jeong, Hong-Beom Bae, Leyeoin Lee, Woojeong Lee, Joungmin Kim

{"title":"Ramped versus sniffing position for Ambu® AuraGainTM insertion in patients with obesity: a randomized controlled study.","authors":"Hye-Won Jeong, Hong-Beom Bae, Leyeoin Lee, Woojeong Lee, Joungmin Kim","doi":"10.4097/kja.24255","DOIUrl":"10.4097/kja.24255","url":null,"abstract":"Background: The ramped position facilitates mask ventilation and endotracheal intubation in patients with obesity. This study aimed to determine whether the ramped position improves supraglottic airway (SGA) insertion in patients with obesity.Methods: In this prospective, randomized, single-center trial, 48 obese patients undergoing elective surgery were randomized into either ramped or sniffing position groups. The Ambu® AuraGainTM (Ambu A/S), a second-generation SGA, was used. The primary outcome was the time required for the AuraGain insertion. Secondary outcomes included ease and number of insertion attempts, oropharyngeal leak pressure (OLP), and complications. The number needed to treat (NNT) was calculated to ensure ease of insertion.Results: The time required for the AuraGain insertion was significantly shorter in the ramped group than in the sniffing group (13.0 [11.0, 16.0] vs. 24.0 [21.0, 28.0], P < 0.001). The insertion was easier in the ramped group than in the sniffing group (23/24 vs. 13/24, NNT = 2.4 [95% CI, 1.6, 5.0], P = 0.003). The first-attempt success rate was higher in the ramped group than in the sniffing group, although the difference was not statistically significant (22/24 vs. 18/24, P = 0.319). The OLP and postoperative complication rates were not significantly different between the groups.Conclusions: The ramped position reduced the time required for the AuraGain insertion in obese patients while providing comparable airway sealing without increasing adverse events. Therefore, a ramped position may be a more suitable option for SGA insertion in this population.","PeriodicalId":17855,"journal":{"name":"Korean Journal of Anesthesiology","volume":" ","pages":"518-525"},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of remimazolam in reducing postoperative nausea and vomiting: a superior alternative anesthetic for total intravenous anesthesia? 雷马唑仑减轻术后恶心和呕吐的功效：全静脉麻醉的最佳替代麻醉剂？

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-08-01 Epub Date: 2024-07-18 DOI: 10.4097/kja.24465

Jong Wook Song

引用次数: 0

Tranexamic acid - a promising hemostatic agent with limitations: a narrative review. 氨甲环酸--一种前景看好但存在局限性的止血剂：综述。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-08-01 Epub Date: 2023-08-21 DOI: 10.4097/kja.23530

Dong Joon Kim, Su Yeon Cho, Ki Tae Jung

引用次数: 0

Comparison of remimazolam and desflurane in emergence agitation after general anesthesia for nasal surgery: a prospective randomized controlled study. 比较瑞马唑仑和地氟醚在鼻腔手术全身麻醉后出现躁动的情况：前瞻性随机对照研究。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-08-01 Epub Date: 2024-05-07 DOI: 10.4097/kja.23953

Sung-Ae Cho, So-Min Ahn, Woojin Kwon, Tae-Yun Sung

{"title":"Comparison of remimazolam and desflurane in emergence agitation after general anesthesia for nasal surgery: a prospective randomized controlled study.","authors":"Sung-Ae Cho, So-Min Ahn, Woojin Kwon, Tae-Yun Sung","doi":"10.4097/kja.23953","DOIUrl":"10.4097/kja.23953","url":null,"abstract":"Background: Remimazolam is an ultrashort-acting benzodiazepine. Few studies have evaluated the effects of remimazolam-based total intravenous anesthesia (TIVA) on emergence agitation (EA). This study aimed to compare the incidence and severity of EA between TIVA using remimazolam and desflurane.Methods: This prospective randomized controlled study enrolled 76 patients who underwent nasal surgery under general anesthesia. Patients were randomized into two groups of 38 each: desflurane-nitrous oxide (N2O) (DN) and remimazolam-remifentanil (RR) groups. The same protocol was used for each group from induction to emergence, except for the use of different anesthetics during maintenance of anesthesia according to the assigned group: desflurane and nitrous oxide for the DN group and remimazolam and remifentanil for the RR group. The incidence of EA as the primary outcome was evaluated using three scales: Ricker Sedation-Agitation Scale, Richmond Agitation-Sedation Scale, and Aono's four-point agitation scale. Additionally, hemodynamic changes during emergence and postoperative sense of suffocation were compared.Results: The incidence of EA was significantly lower in the RR group than in the DN group in all three types of EA assessment scales (all P < 0.001). During emergence, the change in heart rate differed between the two groups (P = 0.002). The sense of suffocation was lower in the RR group than in the DN group (P = 0.027).Conclusions: RR reduced the incidence and severity of EA in patients undergoing nasal surgery under general anesthesia. In addition, RR was favorable for managing hemodynamics and postoperative sense of suffocation.","PeriodicalId":17855,"journal":{"name":"Korean Journal of Anesthesiology","volume":" ","pages":"432-440"},"PeriodicalIF":4.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Key insights and challeneges in noninferiority trials. 非劣效性试验的关键见解和挑战。

IF 4.2 4区医学

Korean Journal of Anesthesiology Pub Date : 2024-08-01 Epub Date: 2024-07-30 DOI: 10.4097/kja.23534

Boohwi Hong, Dong-Kyu Lee

引用次数: 0