Journal of University Medical & Dental College最新文献

{"title":"Antimicrobial Susceptibility Pattern of Methicillin-Resistant Staphylococcus aureus in a Tertiary care Hospital","authors":"Aqsa Aslam, Wajiha Mahjabeen, Muhammad Zia ul Rehman, Sana Qanber Abbasi, Nazish Babar, Huzaifa Saleem","doi":"10.37723/jumdc.v13i4.761","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.761","url":null,"abstract":"Background & Objective: Methicillin-resistant Staphylococcus aureus (MRSA) has become a major therapeutic issue across the world. The current study is designed to evaluate the trends in the susceptibility pattern of MRSA strains isolated from various clinical samples in a tertiary care hospital in Islamabad. The antimicrobial susceptibility pattern will not only add data but will also guide us about treatment options for MRSA infection. \u0000Methodology: This study was done in the Microbiology laboratory of Dr. Akbar Niazi Teaching Hospital, Islamabad after approval from the institutional ethical committee from May 2021 to December 2021. It was a descriptive cross-sectional study in which 155 clinical samples which revealed growth of Staphylococcus aureus were included by nonprobability convenient sampling technique. The cefoxitin disk was used to detect methicillin susceptibility. The susceptibility pattern of MRSA strains was seen against various antibiotics. The data entry and analysis were done using the Statistical Package for the Social Sciences (SPSS) version 25. \u0000Results: Out of 155 isolates of Staphylococcus aureus, 90(58.1%) isolates were MRSA. All the MRSA strains were sensitive to linezolid and vancomycin. The majority of the strains were sensitive to minocycline (71.1%), gentamycin (70%), and clindamycin (68.9%). The strains showed a relatively lower degree of sensitivity to other antimicrobials: trimethoprim/sulfamethoxazole (20%), ciprofloxacin (25.6%), levofloxacin (31.1%), and erythromycin (24.4%). There were only 2 MRSA strains isolated from urine samples which were sensitive to nitrofurantoin. \u0000Conclusion: There is a very high prevalence of MRSA in our setup. The majority of isolates are also resistant to macrolides, trimethoprim-sulfamethoxazole, and fluoroquinolones. Fortunately, all the MRSA strains are sensitive to vancomycin and linezolid.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical & Dental College","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134499902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-esteem, optimism and their associated factors among Optometry students at the University of Lahore","authors":"Mudassar Ali Roomi, Ansa Farooq, Ahmad Bilal, Shagufta Khaliq, Hafsa Iqbal, Muhammad Imran Ashraf","doi":"10.37723/jumdc.v13i4.736","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.736","url":null,"abstract":"BACKGROUND & OBJECTIVE: Self-esteem and optimism are important for students’ success. Our objectives were (a) to determine self-esteem and life-orientation (optimism) levels among Optometry students in the Department of Optometry & Vision Sciences at the University of Lahore (UoL) (b) to investigate associations between sociodemographic factors, self-esteem, and optimism. \u0000METHODOLOGY: This cross-sectional study was conducted during November 2021 to December 2021 at the Department of Optometry and Vision Sciences, UoL. A total of 168 Optometry students were recruited by convenience sampling. Self-esteem was estimated using Rosenberg Self-Esteem Questionnaire. Life Orientation Test-Revised (LOT-R) questionnaire was used to measure optimism. Ethical approval was obtained from the Institutional Review Board of the UoL. Chi-square was used to determine associations between sociodemographic variables, self-esteem, and optimism. \u0000RESULTS: Mean self-esteem score was 18.48±3.86 (range:8-30). About 20% of students had low self-esteem. The mean life orientation score was 14.15±2.8 (range:5-24). About 43% of students had low optimism. Significant associations were found between self-esteem, reason of admission in the Optometry program with p-value=0.001, family income  p=0.037 , choice of the Optometry program p=0.036, and reason of admission in the Optometry program 0.032. \u0000CONCLUSION: Low self-esteem and low optimism have been observed among a significant percentage of Optometry students at the UoL. Reason of admission in the Optometry program and family income were significantly associated factors. Students’ own decision to choose a study program may increase their self-esteem and optimism. Financial assistance for students from the low socioeconomic background may be a positive approach to boost their self-esteem and optimism. Teachers, parents, and counselors should support the students to increase their self-esteem and optimism. ","PeriodicalId":178216,"journal":{"name":"Journal of University Medical & Dental College","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115482557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative effects of parsley leaves aqueous extract and ramipril on gentamicin induced nephrotoxicity in rats","authors":"Eisha Akram, Akbar Waheed, Rukhsana Munawar, Sidra Mumal, Abdul Azeem","doi":"10.37723/jumdc.v13i4.729","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.729","url":null,"abstract":"BACKGROUND & OBJECTIVE: Rats are commonly used in experimental studies as they have a smaller body size, they are easily available, and their genetic profiles are similar to each other as compared to humans. Kidney pathologies are the result of an imbalance between reactive oxygen species and antioxidants. Parsley aqueous extract is rich in polyphenolic contents and has nephroprotective effects. The objective of this study is to observe the effects of ramipril and parsley leaves aqueous extract in gentamicin induced nephrotoxicity. \u0000METHODOLOGY: An Experimental study consisting of 40 healthy male albino rats were randomly distributed into two categories after taking samples for baseline values of urea and creatinine: Category 1 consisted of a control group (Group 1) having 10 rats, while category 2 comprised of 30 rats, divided into three experimental groups after being given intraperitoneal injections of gentamicin (80mg/kg) per day. Group 2 was taken as disease control, while group 3 and group 4 were parsley treated and ramipril treated for 28 days, respectively. Biochemical markers (serum urea and creatinine) were done at day 35. SPSS version 22 was applied for Statistical analysis. One-way ANOVA test was used to determine any difference in mean values. Post hoc tuckeys test was applied for multiple comparisons amongst groups. p<0.05 was measured as significant. \u0000RESULTS: The treatment decreased the levels of serum urea and creatinine in nephrotoxic rats in group 3 (parsley treated group) and group 4 (ramipril treated group) in comparison to group 2. Group 3 had significantly reduced biochemical markers (p<0.05). \u0000CONCLUSION: Parsley leaves extract significantly reduced the serum urea and creatinine levels as compared to ramipril.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"407 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116035267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between transverse cerebellar diameter and gestational age in second and third trimester of singleton pregnancies","authors":"Beenish Nadeem, Anam Zahoor","doi":"10.37723/jumdc.v13i4.754","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.754","url":null,"abstract":"BACKGROUND & OBJECTIVE: Trans cerebellar diameter stands out as an important fetal parameter for estimating gestational age in second and third trimester when all the other parameters start showing margin of error of 3 to 4weeks. The study was designed with intent to gather more evidence on TCD measurements validity.  This will help us in using TCD on routine basis in advance pregnancies. Our objective is to determine the correlation between mean transverse cerebellar diameter and mean gestational age in 20 to 40 weeks of gestation. \u0000METHODOLOGY: This research is being conducted at radiology department of Social Security Hospital Islamabad from 1-02-2022 till 01-06-2022. Non-probability convenient sampling was done and a total of sixty (n=60) healthy women with a singleton pregnancy between 18 to 40 years of age with gestational age of 20 to 40 weeks as confirmed by ultrasound were enrolled in the study. An expert radiologist used Logic P6 ultrasonography machine during the study. TCD, HC, BPD and FL was measured in each patient and correlated with gestational age. Pearson correlation coefficient was computed using SPSS-17.0. \u0000RESULTS: Significant and strong positive correlation (r=0.98) and p<0.001 was found between TCD measured by ultrasonography and gestational age at a 0.05 significance level. \u0000CONCLUSION: Significant and strong positive correlation was found between TCD measured by ultrasonography and gestational age.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125952669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hair manifestations in factory workers with arsenic exposure in Hayatabad industrial estate Peshawar, Pakistan","authors":"Mahvish Javed, Zilli Huma, Zeeshan Kibria, Muhammad Adeel Alam Shah","doi":"10.37723/jumdc.v13i4.750","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.750","url":null,"abstract":"BACKGROUND & OBJECTIVE: Arsenic is present both naturally and from manmade sources like factory effluents. Contamination by arsenic of the groundwater is a major source of health detriment in south-east Asian countries. The aim of this study was to identify levels of arsenic in drinking water sources and factory effluents and to analyse arsenic levels in hair samples from factory workers and their families, along with morphological changes in hair in industrial workers in Peshawar. \u0000METHODOLOGY: Water and hair samples were collected by random sampling from a labor colony of 81 factory and non-factory household members living and working in the same industrial estate and analyzed for arsenic. Hair morphology was carried out in histomorphology laboratory at Khyber Medical University, Peshawar. The results obtained from both groups were compared with normal hair histomorphology. The data was analyzed by using SPSS version 20. \u0000RESULTS: The arsenic level in drinking water, colony tube wells and households was not within the permissible level of WHO (10µg/L). The arsenic level in factory effluent was 68µg/l (Pakistan Government's acceptable level is 50µg/L). The difference was statistically significant p≤0.001 between the two groups, the factory workers had a relatively higher level of arsenic, ~34ppb, in their scalp hair. Hair arsenic level also came out to be <1.00µg/g. There was a wide variation in the histomorphology of the hair samples in both groups. \u0000CONCLUSION: Elevated levels of arsenic in factory effluent demonstrate improper decontamination. The arsenic levels were within permissible levels, long term effects cannot be ruled out.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131081156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of attendance in academic performance of male and female medical students in pre clinical years: A descriptive study","authors":"M. A. Cheema, Amra Rehman, Saba Khalid, Syed Muhammad Hammad Ali, Rida Ajmal Khane","doi":"10.37723/jumdc.v13i4.682","DOIUrl":"https://doi.org/10.37723/jumdc.v13i4.682","url":null,"abstract":"BACKGROUND & OBJECTIVE: In-person attendance at medical school is a growing concern since the inception of readily available online resources. In Pakistan, a student who fails to keep up with what has been taught in class often finds academic assessments in jeopardy. The present study aimed to assess the role of attendance in academic performance among preclinical male and female students in the subject of Physiology. \u0000METHODOLOGY: Overall attendance in lectures, tutorials, and practical classes was recorded from first and second-year MBBS students’ records during the academic session of 2016-17. Scores in all written, viva voce and formative assessments were used to represent the academic performance. Data were analyzed by SPSS version 23.0. Shapiro-Wilk’s statistics were used to determine distributions. The median interquartile range (IQR) was used for non-normally distributed variables. A p-value of ≤ 0.05 was considered statistically significant. \u0000RESULTS: A total of 287 preclinical students were included in the study. Out of them, 110 (38.3%) were male, and 177 (61.7%) were females. Girls had higher overall attendance, 91% (87.2-95) as compared to the boys, 88.9% (85.6-93.2) of both MBBS years (p = 0.015). Girls also had a significantly higher percentage of scores in all formative assessments in tutorials, 65.7% (59.2-73.9) as compared to the boys, 59.6% (53.1-66.4) (p < 0.001). A positive correlation of all academic performance parameters was observed with the overall attendance (p < 0.001). The same correlations were also seen among the groups based on gender as well as the MBBS year. \u0000CONCLUSION:  Attendance at medical school, especially in the subject of Physiology, is related to better academic performance. Female students are more regular and have the habit of attending classes which reflects on their better performance in formative assessments. A satisfactory overall attendance observed in our study might be due to the mandatory attendance policy of our medical school. ","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115708144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trend and future of infant mortality in Pakistan","authors":"Zartashia Shabbir, Anila Riaz, Fiaz Ahmad, Muhammad Imran shakoor","doi":"10.37723/jumdc.v13i3.649","DOIUrl":"https://doi.org/10.37723/jumdc.v13i3.649","url":null,"abstract":"In South Asia, Pakistan is contributing to the highest childhood mortality, including infant mortality. Child mortality has been declined globally, but Pakistan is still struggling and far behind the targets of Sustainable Development Goals. There are several reasons behind high childhood mortality, including socioeconomic determinants and a lack of effective implementation of health-related policies, particularly in primary health care settings. In the present study, we use the stochastic univariate models to uncover the trend of infant mortality by using more than half of the century data from 1960-2017.The secondary data on infant mortality rate from 1960 to 2017 was extracted from World Bank Dataset. Descriptive and time series analysis were applied by using the programming language R. The median infant mortality rate was 109 per 1,000 live births, whereas a higher mortality rate (189.8/1000) was reported in 1960. A gradual decline in infant mortality rates is experienced every year. The mortality rate went down below 100/1,000 live births from 1993 and remained 61.2/1,000 in 2017. ARIMA (1, 2, 2) is an adequate forecasting model selected by using the Auto ARIMA function with a root mean square error is 0.1006. Five years ahead forecast is obtained and yielded that infant mortality rate is expected to remain in 2018 [59.54, C.I (59.34 - 59.73)], 2019 [57.93, C.I (57.47 - 58.40)], 2020 [56.39, C.I (55.48 - 57.30)], 2021 [54.90, C.I (53.35 - 56.45)] and 2022 [53.47, C.I (51.05 - 55.88)]. The decreasing trend is expected in the infant mortality rate in Pakistan.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127896503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The conundrum of new coronavirus variants and poor uptake of booster dose: building a narrative against vaccine hesitancy in Pakistan","authors":"Naeem Mubarak, Fatima Rehman Rana, Asad Majeed Khan, Sabba Kanwal, Sundus Tariq, Saba Tariq","doi":"10.37723/jumdc.v13i3.762","DOIUrl":"https://doi.org/10.37723/jumdc.v13i3.762","url":null,"abstract":"expect many new anti-viral treatments in the year three of the pandemic, however, the vaccines remain one of the most effective public health intervention to prevent hospitalization and deaths. Nevertheless, to achieve long-term protection in the form of herd or population immunity, 75-90% of the population should receive a complete course of vaccination [2] . However, not all people accept vaccines and there exists a substantial population that remains against the whole concept of vaccination leading to the social phenomenon of vaccine hesitancy. Although the supply of vaccines was optimal in the last quarter of 2021, low & middle income countries will remain under-vaccinated for much of 2022, due to the major hindrance posed by the rampant vaccine hesitancy. This situation may lead to higher mortality and morbidity rates and weaker economic recoveries [3] .","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"50 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129865932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of oral hygiene status among children admitted in intensive care unit at tertiary care Hospital Karachi","authors":"Zulifqar Ali, Badil, Nazia Khan","doi":"10.37723/jumdc.v13i3.651","DOIUrl":"https://doi.org/10.37723/jumdc.v13i3.651","url":null,"abstract":"BACKGROUND & OBJECTIVE: Oral assessment is the vital responsibility of the nurse that can lead to preventing the illness and maintaining health in the pediatric intensive care unit. The objective of this study was to assess oral hygiene and determine associated factors among children admitted in pediatric intensive care unit at tertiary care public sector hospitals Karachi \u0000METHODOLOGY: This Analytical cross-sectional study was accomplished at a tertiary care hospital in the pediatric intensive care unit in Dr. Ruth K.M. Pfau Civil Hospital at Karachi. A consecutive sampling technique was used to approach the study participant. Study participants were approached through a consecutive sampling technique. The calculated sample size was 92, it was calculated by the software \"sample size determination in Health Sciences\". Beck oral assessment scale (BOAS) was used for data collection. p<0.05 was considered statistically significant. \u0000RESULTS: \u0000Out of the total 110 study participants, 80(72.75 %) were males, and 30(27.3%) were females, with overall mean age 8.45±2.97 years. In this study, 32(29.1%) children have mild dysfunction, whereas majority of the children have moderate dysfunction 67(60.9%). However severe dysfunction, which is most dangerous, was also found in 11(10.0%) children. According to results, the mild dysfunction and moderate/ severe were found statistically significant with age and gender p<0.038 and 0.013, respectively. \u0000CONCLUSION: It is concluded that almost all the children in the Pediatric Intensive Care Unit of a public sector tertiary care hospital were suffering with dysfunctions, and the majority were suffering with moderate to severe dysfunction on the basis of Beck oral assessment scale.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115765990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yield of gene Xpert in diagnosing patients with pleural tuberculosis presenting to a tertiary care hospital","authors":"Awais Aslam, Istikhar Ali Sajjad, Abdul Wajid Khan, Hafiz Muhammad Taha Waqas, Zara Saleem, Hina Imtiaz","doi":"10.37723/jumdc.v13i3.733","DOIUrl":"https://doi.org/10.37723/jumdc.v13i3.733","url":null,"abstract":"BACKGROUND & OBJECTIVE: Pleural tuberculosis is a common type of extrapulmonary tuberculosis and remains a common problem for pulmonologists. Early detection of tuberculosis is a global priority for TB control. Gene Xpert is a real-time PCR, which can reveal Mycobacterium tuberculosis within 2 hours. This study will bridge the gap and help the pulmonologist for deciding on the use of Gene Xpert as diagnostic tool for pleural tuberculosis. Our objective is to find the frequency of positive Gene Xpert among patients of pleural tuberculosis presenting to tertiary care hospital. \u0000METHODOLOGY: A Cross-sectional study was conducted in the Department of Pulmonology, Aziz Fatima Hospital, Faisalabad from 26 February 2022 to 25 March 2022. Total 187 patients ages between 15-80 years having pleural tuberculosis diagnosed during last 6 months were included in the study. Patients already taking anti-tuberculosis therapy were excluded. Pleural fluid was processed in Aziz Fatima Hospital, Faisalabad laboratory for Gene Xpert immediately. Reports were collected next day and noted in the proforma. Positive Gene Xpert as per operational definition. Data was stratified for variables like age, gender, comorbidities (like diabetes mellitus, HIV and smoking status). Chi-square test was applied taking p-value ≤ 0.05 as significant. \u0000RESULTS: Out of 187 patients, mean age was 43.71±14.93 years. 95(50.8%) patients were male and 92(49.2%) patients were females. Positive Gene Xpert was found in 49(26.2%) patients. Positive Gene Xpert is more common in patients of HIV positive 27 (38.6%) than the 22 (18.8%) patients of HIV negative shows significant association (p-value = 0.001). Out of 72 diabetic patients, 23(31.9%) patients had positive Gene Xpert and out of 115 non-diabetic patients, 26(22.6%) patients had positive Gene Xpert with p-value = 0.158.  Out of 82 smoker patients, 27(32.9%) patients had positive Gene Xpert and out of 105 non-smoker patients, 22(21%) patients had positive Gene Xpert with p-value=0.065.  Out of 57 HIV positive patients, 27(47.4%) patients had positive Gene Xpert and out of 130 HIV negative patients, 22(16.9%) patients had positive Gene Xpert with p-value =0.001. \u0000CONCLUSION:   Gene Xpert can be used as a reliable investigation for detection of pleural tuberculosis and timely initiation of treatment.","PeriodicalId":178216,"journal":{"name":"Journal of University Medical &amp; Dental College","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132972563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}