Korean Journal of Urology最新文献

{"title":"Pediatric urology in the KJU.","authors":"Jung Yoon Kang","doi":"10.4111/kju.2015.56.4.255","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.255","url":null,"abstract":"Korea has four distinct seasons: spring, summer, fall, and winter. April is sunny springtime, with new buds on the trees and fantastic cherry blossoms in the streets all over the country. Childhood and adolescence are like the spring season in a human's lifetime. They are an energetic and dynamic period during which growth and regeneration are occurring every day. The Korean Society of Pediatric Urology (KSPU) was established on April 25, 1992. It originated from the Korean Pediatric Urology study group, which was founded in 1987. KSPU has participated in the Asia Pacific Association of Pediatric Urologists (APAPU) since 1999, and the annual meetings of the APAPU were twice held in Korea, in Seoul in 2002 and in Busan in 2012. KSPU has made an effort to have a broad academic exchange with the world. KSPU had published its own journal, the Korean Journal of Pediatric Urology (KJSPU), since April 2009. KJSPU was published twice a year for 5 years, and it was united with the Korean Journal of Urology (KJU) in January 2014. The main reasons for the merger of the two journals were the overlap in scope and members among the societies and the expectation to provide more in-depth knowledge in the section of Pediatric Urology and to improve the overall quality of the KJU [1]. After the merger, about 50% of the manuscripts for pediatric urology submitted to the KJU came from outside Korea, including Turkey, Iran, India, Saudi Arabia, Egypt, and Tunisia in Africa. The acceptance rate of the articles for pediatric urology was 53.3% in 2014. This was slightly higher than the overall acceptance rate of KJU, which was 46.1% in 2014 [2]. Ten pediatric-related articles including one review article, which was about robot-assisted laparoscopic surgery, were published in 2014. Several interesting papers were published in 2014, including a research study on a urinary biomarker in neonatal hydronephrosis [3] and a multicenter observational study about pediatric neurogenic bladder [4]. In Korea, more than 35 centers and hospitals have the da Vinci robot system (Intuitive Surgical Inc., Sunnyvale, CA, USA). About 7,000 surgeries are performed annually, and the number of cases is increasing yearly. However, few robot-assisted surgeries have been performed in the field of pediatric urology in Korea. Except for the review article, one case report about infant robotic surgery was published in the KJU [5]. Accordingly, articles related to robot-assisted pediatric surgery are welcome in the KJU. KJU has a special advantage in the genomics/stem cell field in urology and the ease of access to video clips compared with various other urologic journals. Also, KJU has a well-designed peer review system, and the key focus in 2015 will be on rapid critical reviews, fast publication, and easy-to-access online audiovisual content [6]. Therefore, I sincerely ask pediatric urologists worldwide to submit manuscripts to the KJU, which will be an excellent jour","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"255-6"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33092648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of nanoparticles to monitor human mesenchymal stem cells transplanted into penile cavernosum of rats with erectile dysfunction.","authors":"Jae Heon Kim,&nbsp;Hong Jun Lee,&nbsp;Seung Hwan Doo,&nbsp;Won Jae Yang,&nbsp;Dongho Choi,&nbsp;Jung Hoon Kim,&nbsp;Jong Ho Won,&nbsp;Yun Seob Song","doi":"10.4111/kju.2015.56.4.280","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.280","url":null,"abstract":"<p><strong>Purpose: </strong>This study was performed to examine the treatment of erectile dysfunction by use of superparamagnetic iron oxide nanoparticles-labeled human mesenchymal stem cells (SPION-MSCs) transplanted into the cavernous nerve injured cavernosa of rats as monitored by molecular magnetic resonance imaging (MRI).</p><p><strong>Materials and methods: </strong>Eight-week-old male Sprague-Dawley rats were divided into three groups of 10 rats each: group 1, sham operation; group 2, cavernous nerve injury; group 3, SPION-MSC treatment after cavernous nerve injury. Immediately after the cavernous nerve injury in group 3, SPION-MSCs were injected into the cavernous nerve injured cavernosa. Serial T2-weighted MRI was done immediately after injection and at 2 and 4 weeks. Erectile response was assessed by cavernous nerve stimulation at 2 and 4 weeks.</p><p><strong>Results: </strong>Prussian blue staining of SPION-MSCs revealed abundant uptake of SPION in the cytoplasm. After injection of 1×10(6) SPION-MSCs into the cavernosa of rats, T2-weighted MRI showed a clear hypointense signal induced by the injection. The presence of SPION in the corpora cavernosa was confirmed with Prussian blue staining. At 2 and 4 weeks, rats with cavernous nerve injury had significantly lower erectile function than did rats without cavernous nerve injury (p<0.05). The group transplanted with SPION-MSCs showed higher erectile function than did the group without SPION-MSCs (p<0.05). The presence of SPION-MSCs for up to 4 weeks was confirmed by MRI imaging and Prussian blue staining in the corpus cavernosa.</p><p><strong>Conclusions: </strong>Transplanted SPION-MSCs existed for up to 4 weeks in the cavernous nerve injured cavernosa of rats. Erectile dysfunction recovered and could be monitored by MRI.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"280-7"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.280","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33092652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of intraprostatic architecture and regrowth velocity for considering discontinuation of dutasteride after combination therapy with an alpha blocker: a prospective, pilot study.","authors":"Tetsuya Shindo,&nbsp;Kohei Hashimoto,&nbsp;Takashi Shimizu,&nbsp;Naoki Itoh,&nbsp;Naoya Masumori","doi":"10.4111/kju.2015.56.4.305","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.305","url":null,"abstract":"<p><strong>Purpose: </strong>We conducted a prospective single-center study to evaluate the possibility of discontinuation of dutasteride after combination therapy with an alpha blocker for benign prostatic hyperplasia (BPH).</p><p><strong>Materials and methods: </strong>We prospectively treated BPH patients with an alpha blocker and dutasteride (0.5 mg/d). Patients who had been treated with alpha blockers against BPH for more than 2 months were eligible, and 20 patients were included in the study. After 6 months of combination therapy, dutasteride was discontinued. Patients were followed for 12 months after cessation. Prostate volume, intraprostatic architecture determined by transrectal ultrasound, peak urinary flow rate, postvoid residual urine volume, and the serum prostate-specific antigen level were evaluated every 6 months, and the International Prostate Symptom Score and overactive bladder symptom score (OABSS) every 3 months. Patients were allowed to restart dutasteride during the follow-up period according to their desire.</p><p><strong>Results: </strong>Twelve patients (12/20, 60%) restarted the combination therapy from 6 to 12 months into the follow-up period. For patients who restarted dutasteride, the prostate volume and OABSS had increased and worsened after discontinuation, respectively. A visible transition zone with a clear border on transrectal ultrasound at baseline and regrowth of the prostate after discontinuation of dutasteride were risk factors for restarting the therapy (Mann-Whitney U test: p=0.008, p=0.017).</p><p><strong>Conclusions: </strong>Prostatic enlargement after discontinuation of dutasteride differs among patients. Rapid regrowth of the prostate leads to deterioration of storage symptoms and a tendency to restart dutasteride. Baseline intraprostatic architecture may be a predictive factor for whether the patient is a good candidate for discontinuation.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"305-9"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.305","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33097683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elderly men over 65 years of age with late-onset hypogonadism benefit as much from testosterone treatment as do younger men.","authors":"Farid Saad,&nbsp;Aksam Yassin,&nbsp;Ahmad Haider,&nbsp;Gheorghe Doros,&nbsp;Louis Gooren","doi":"10.4111/kju.2015.56.4.310","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.310","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the potential benefits of testosterone administration to elderly men (>65 years) with late-onset hypogonadism (LOH) in comparison with younger men and to assess the safety of testosterone administration to elderly men.</p><p><strong>Materials and methods: </strong>A total of 561 hypogonadal men from two registry studies were divided into age groups of ≤65 years (group Y, n=450; range, 32-65 years) and >65 years (group O, n=111; range, 66-84 years). Following an initial 6-week interval, all men were treated with 3-month injections of parenteral testosterone undecanoate for up to 6 years.</p><p><strong>Results: </strong>Over the 6 years, there was a progressive decrease of body weight and waist circumference. Beneficial effects on lipids and other metabolic factors and on psychological and sexual functioning progressed over the first 24 to 42 months and were sustained. Rather than a deterioration, there was an improvement of urinary parameters. Prostate volume and prostate-specific antigen increased moderately. Hematocrit levels increased but remained within safe margins.</p><p><strong>Conclusions: </strong>The benefits of restoring serum testosterone in men with LOH were not significantly different between men older than 65 years of age and younger men. There were no indications that side effects were more severe in elderly men. The effects on prostate and urinary function and hematocrit were within safe margins. Age itself need not be a contraindication to testosterone treatment of elderly men with LOH.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"310-7"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.310","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33097684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right sided double inferior vena cava with obstructed retrocaval ureter: Managed with single incision multiple port laparoscopic technique using \"Santosh Postgraduate Institute tacking ureteric fixation technique\".","authors":"Santosh Kumar,&nbsp;Shivanshu Singh,&nbsp;Nitin Garg","doi":"10.4111/kju.2015.56.4.330","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.330","url":null,"abstract":"<p><p>Right double inferior vena cava with obstructed retrocaval ureter is an extremely rare anomaly with only a few reported cases in the literature. To the best of our knowledge, this is the first case report describing ureteric repair by use of a single-incision laparoscopic technique. In addition, this report addresses the underlying surgical challenges of this repair and provides a brief review of the embryology of this anomaly. The \"Santosh Postgraduate Institute ureteric tacking fixation technique\" provides ease of end-to-end uretero-ureteric anastomosis in a single-incision laparoscopic surgery. </p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"330-3"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.330","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33097687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of calcific density in pediatric patients with testicular microlithiasis.","authors":"Bumjin Lim,&nbsp;Sang Hoon Song,&nbsp;Geehyun Song,&nbsp;Kun Suk Kim","doi":"10.4111/kju.2015.56.4.318","DOIUrl":"https://doi.org/10.4111/kju.2015.56.4.318","url":null,"abstract":"<p><strong>Purpose: </strong>Testicular microlithiasis (TM) is a relatively rare clinical entity of controversial significance characterized by the existence of hydroxyapatite microliths located in the seminiferous tubules. The aim of this study was to observe the natural course of changes in the calcific density of pediatric TM.</p><p><strong>Materials and methods: </strong>We included a total of 23 TM patients undergoing scrotal ultrasound (US) on at least two occasions from July 1997 to August 2014. We retrospectively analyzed the patient characteristics, clinical manifestations, specific pathological features, and clinical outcomes. We measured the calcified area and compared the calcific density between the initial and final USs.</p><p><strong>Results: </strong>The mean age at diagnosis was 11.3±4.6 years, and the follow-up period was 79.1±38.8 months (range, 25.4-152.9 months). During the follow-up period, no patients developed testicular cancer. Calcific density on US was increased in the last versus the initial US, but not to a statistically significant degree (3.74%±6.0% vs. 3.06%±4.38%, respectively, p=0.147). When we defined groups with increased and decreased calcification, we found that diffuse TM was categorized into the increased group to a greater degree than focal TM (10/20 vs. 4/23, respectively, p=0.049). In addition, five of eight cases of cryptorchidism (including two cases of bilateral cryptorchidism) were categorized in the increased calcification group.</p><p><strong>Conclusions: </strong>Diffuse TM and cryptorchidism tend to increase calcific density. Close observation is therefore recommended for cases of TM combined with cryptorchidism and cases of diffuse TM.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 4","pages":"318-23"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.4.318","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33097685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel transurethral resection technique for superficial flat bladder tumor: grasp and bite technique.","authors":"Kyung Jin Oh,&nbsp;Yoo-Duk Choi,&nbsp;Ho Suck Chung,&nbsp;Eu Chang Hwang,&nbsp;Seung Il Jung,&nbsp;Dong Deuk Kwon,&nbsp;Kwangsung Park,&nbsp;Taek Won Kang","doi":"10.4111/kju.2015.56.3.227","DOIUrl":"https://doi.org/10.4111/kju.2015.56.3.227","url":null,"abstract":"<p><strong>Purpose: </strong>Transurethral resection of bladder tumor (TURBT) can be a challenging procedure for an inexperienced surgeon. We suggest an easy technique for TURBT, which we have named the \"grasp and bite\" technique. We describe this technique and compare its effectiveness and safety with that of conventional TURBT.</p><p><strong>Materials and methods: </strong>Monopolar TURBT (24-Fr Karl Storz) was performed in 35 patients who had superficial bladder tumors. After defining the tumor margin, the tumor and surrounding mucosa were grasped by use of a loop electrode and resectoscope sheath. With tight grasping, linear moving resection was performed. The patients' demographic, intraoperative, and postoperative data were analyzed between the conventional and grasp and bite TURBT groups.</p><p><strong>Results: </strong>Of 35 patients, 16 patients underwent conventional TURBT (group 1), and the other 19 patients underwent grasp and bite TURBT (group 2). Both groups were similar in age, tumor multiplicity, size, anesthesia method, and location. Grasp and bite TURBT could be performed as safely and effectively as conventional TURBT. There were no significant differences in irrigation duration, urethral catheterization, postoperative hemoglobin drop, or length of hospital stay. No significant side effects such as bladder perforation, severe obturator reflex, or persistent bleeding occurred. There were no significant pathological differences between specimens according to the type of resection technique.</p><p><strong>Conclusions: </strong>The grasp and bite TURBT technique was feasible for superficial bladder tumors. It may be a good tool for inexperienced surgeons owing to its convenient and easy manner.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 3","pages":"227-32"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.3.227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33123532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of penile prosthetic devices.","authors":"Brian Le,&nbsp;Arthur L Burnett","doi":"10.4111/kju.2015.56.3.179","DOIUrl":"https://doi.org/10.4111/kju.2015.56.3.179","url":null,"abstract":"<p><p>Penile implant usage dates to the 16th century yet penile implants to treat erectile dysfunction did not occur until nearly four centuries later. The modern era of penile implants has progressed rapidly over the past 50 years as physicians' knowledge of effective materials for penile prostheses and surgical techniques has improved. Herein, we describe the history of penile prosthetics and the constant quest to improve the technology. Elements of the design from the first inflatable penile prosthesis by Scott and colleagues and the Small-Carrion malleable penile prosthesis are still found in present iterations of these devices. While there have been significant improvements in penile prosthesis design, the promise of an ideal prosthetic device remains elusive. As other erectile dysfunction therapies emerge, penile prostheses will have to continue to demonstrate a competitive advantage. A particular strength of penile prostheses is their efficacy regardless of etiology, thus allowing treatment of even the most refractory cases. </p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 3","pages":"179-86"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.3.179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33124092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of weight reduction on the severity of lower urinary tract symptoms in obese male patients with benign prostatic hyperplasia: a randomized controlled trial.","authors":"Chi-Hang Yee,&nbsp;Wing-Yee So,&nbsp;Sidney K H Yip,&nbsp;Edwin Wu,&nbsp;Phyllis Yau,&nbsp;Chi-Fai Ng","doi":"10.4111/kju.2015.56.3.240","DOIUrl":"https://doi.org/10.4111/kju.2015.56.3.240","url":null,"abstract":"<p><strong>Purpose: </strong>We assessed whether weight reduction is an effective intervention for the management of lower urinary tract symptoms (LUTS) and investigated the relationship between obesity and LUTS.</p><p><strong>Materials and methods: </strong>This was a prospective randomized controlled trial that enrolled obese men older than 50 years with LUTS. The study period was 52 weeks. All patients received standardized alpha-adrenergic blocker therapy for the treatment of benign prostatic hyperplasia (BPH) during the run-in period. Patients were randomized to receive either a standardized prerecorded video program on the general principle of weight reduction or a comprehensive weight reduction program. Patients were assessed at different time points with symptom assessment, uroflowmetry, transrectal ultrasound, and metabolic assessment.</p><p><strong>Results: </strong>Sixty-five patients were allocated to each study arm. After the study period, no significant difference in weight reduction was found between the two arms. When the pre- and postintervention parameters were compared, none were statistically different between the 2 arms, namely nocturia, International Prostate Symptom Score, quality of life assessment, and uroflowmetry parameters. When the whole study population was taken as a single cohort, these parameters were also not significantly different between the group with a body mass index of 25 to <30 kg/m(2) and the group with a BMI of 30 to 35 kg/m(2).</p><p><strong>Conclusions: </strong>We found no association between obesity and LUTS. This could have been due to the less marked weight difference in our cohort. Whereas weight reduction may be an effective measure to improve LUTS, the implementation of a successful program remains a challenge.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 3","pages":"240-6; discussion 246-7"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.3.240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33123534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of holmium laser enucleation of the prostate for extremely large prostatic adenoma in patients with benign prostatic hyperplasia.","authors":"Myong Kim,&nbsp;Songzhe Piao,&nbsp;Hahn-Ey Lee,&nbsp;Sung Han Kim,&nbsp;Seung-June Oh","doi":"10.4111/kju.2015.56.3.218","DOIUrl":"https://doi.org/10.4111/kju.2015.56.3.218","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) for extremely large prostates.</p><p><strong>Materials and methods: </strong>Patients undergoing HoLEP between July 2008 and December 2013 from the Seoul National University Hospital Benign Prostatic Hyperplasia Database Registry were retrospectively analyzed. The patients were divided into three groups according to their total prostate volume (TPV): group A (TPV<100 mL), group B (100 mL≤TPV<200 mL), and group C (TPV≥200 mL); the clinical data of the three groups were compared. All patients were followed up 2 weeks, 3 months, and 6 months after surgery.</p><p><strong>Results: </strong>A total of 502 patients (group A, 426; group B, 70; group C, 6) with a mean age of 69.0 (standard deviation, ±7.3) years were included in our analysis. The mean prostate volume and prostate-specific antigen level were 68.7±36.9 mL and 4.15±4.24 ng/mL, respectively. The enucleation and morcellation times were longer in group C (p<0.001), and the enucleation efficacy was higher in this group (p<0.001, R(2)=0.399). Moreover, the mean postoperative catheterization and hospitalization periods were significantly longer in group C (p=0.004 and p=0.011, respectively). However, there were no significant differences between the groups in any other postoperative events, including recatheterization, reoperation, urinary tract infection, clot retention, and bladder neck contracture (p range, 0.516-0.913). One patient in group C experienced recurrence of the urethral stricture.</p><p><strong>Conclusions: </strong>HoLEP in patients with an extremely large prostate can be performed efficiently and safely.</p>","PeriodicalId":17819,"journal":{"name":"Korean Journal of Urology","volume":"56 3","pages":"218-26"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4111/kju.2015.56.3.218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33123531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}