Kidney international最新文献

{"title":"Renogram clues to venous compromise in acute kidney injury with a pelvic mass.","authors":"Michael Gilleo, Joseph Fotos, Sabine Karam","doi":"10.1016/j.kint.2026.06.046","DOIUrl":"10.1016/j.kint.2026.06.046","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":" ","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gas in a cyst: emphysematous infection in autosomal dominant polycystic kidney disease post-transplant.","authors":"Michael George Sabe, Matthew Robert Paul Davies","doi":"10.1016/j.kint.2026.06.045","DOIUrl":"10.1016/j.kint.2026.06.045","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":" ","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donor-derived fat emboli in a postreperfusion biopsy.","authors":"Farhana Begum, Satoru Kudose","doi":"10.1016/j.kint.2026.06.047","DOIUrl":"10.1016/j.kint.2026.06.047","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":" ","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iris coloboma in PAX2-related disorder.","authors":"Jawad Iqbal Rather, Rayees Ahmad Sofi","doi":"10.1016/j.kint.2026.07.006","DOIUrl":"10.1016/j.kint.2026.07.006","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":" ","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of the ovarian vein as a collateral pathway in a retroaortic left renal vein.","authors":"Grzegorz Wróbel, Waldemar Białek, Piotr Dembicki, Ryszard Maciejewski","doi":"10.1016/j.kint.2026.07.007","DOIUrl":"10.1016/j.kint.2026.07.007","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":" ","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral blood immune signatures to predict kidney histology and treatment response in lupus nephritis.","authors":"Nicholas Hasle,Shaun W Jackson","doi":"10.1016/j.kint.2026.01.038","DOIUrl":"https://doi.org/10.1016/j.kint.2026.01.038","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"458 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148539074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From gut to uremic toxins: a not-so-innocent alliance between microbiota and enterocytes in chronic kidney disease.","authors":"Sandra Wagner,Ziad A Massy,Laetitia Koppe","doi":"10.1016/j.kint.2026.05.033","DOIUrl":"https://doi.org/10.1016/j.kint.2026.05.033","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"67 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148539226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kidney cancer screening: novel concepts beyond population-level screening","authors":"Sabrina Helena Rossi ,&nbsp;Hannah Harrison ,&nbsp;Oliver Byass ,&nbsp;Jessica Kitt ,&nbsp;Michelle Clark ,&nbsp;Kerrie Massey ,&nbsp;Jason Pawluk ,&nbsp;David Blunt ,&nbsp;Stewart Manning ,&nbsp;Grant D. Stewart","doi":"10.1016/j.kint.2026.02.039","DOIUrl":"10.1016/j.kint.2026.02.039","url":null,"abstract":"<div><div>Screening for kidney cancer has been identified as a research priority by several independent initiatives. Previous work revealed that the relatively low prevalence of kidney cancer in untargeted asymptomatic individuals hinders the cost-effectiveness and clinical utility of population screening. We, therefore, undertake a comprehensive literature review summarizing novel screening concepts beyond whole population screening, including targeting high-risk populations (to increase disease prevalence), screening for kidney cancer in combination with other abdominal conditions (to reduce costs), or combining both of these approaches. Risk-stratified screening may be undertaken using phenotypic and/or genetic risk scores. Phenotypic risk scores for kidney cancer generally achieve reasonable discrimination (area under the receiver operating characteristic curve between 0.67 and 0.71 in a mixed sex cohort), with the best performing model being based on age, sex, body mass index, smoking status, hypertension diagnosis, and systolic and diastolic blood pressure. Adding genetic to phenotypic data is costly and provides only a negligible gain in discrimination (an increase in the area under the receiver operating characteristic curve of 0.007 from 0.716 to 0.723), meaning it is unlikely to represent a clinically useful strategy. Alternatively, screening for kidney cancer may be combined with other conditions to maximize efficiency, including multicancer early detection tests and combined screening using ultrasonography (concurrently with abdominal aortic aneurysm screening) or abdominal computed tomography (concurrently with lung cancer screening). The latter strategy is most promising and has the highest public acceptability. In summary, we highlight benefits and harms of different screening strategies beyond traditional population screening and offer a comprehensive and contemporary summary of recent advances in this field and future research avenues.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"110 1","pages":"Pages 70-77"},"PeriodicalIF":21.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147708523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Case | Relapsing nephrotic syndrome","authors":"Siarhei Dzedzik,&nbsp;Joseph M. Jacobs,&nbsp;Vivette D. D’Agati","doi":"10.1016/j.kint.2026.02.040","DOIUrl":"10.1016/j.kint.2026.02.040","url":null,"abstract":"","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"110 1","pages":"Pages 268-271"},"PeriodicalIF":21.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independent association between acute kidney injury and kidney function trajectory","authors":"Victor E. Prado ,&nbsp;Ian E. McCoy ,&nbsp;Yue Zhang ,&nbsp;Jesse Y. Hsu ,&nbsp;Kathleen D. Liu ,&nbsp;Anthony N. Muiru ,&nbsp;Vernon C. Chinchilli ,&nbsp;Steven G. Coca ,&nbsp;Alan S. Go ,&nbsp;Jonathan Himmelfarb ,&nbsp;James S. Kaufman ,&nbsp;Paul L. Kimmel ,&nbsp;T. Alp Ikizler ,&nbsp;Chirag R. Parikh ,&nbsp;Edward D. Siew ,&nbsp;Mark M. Wurfel ,&nbsp;Chi-yuan Hsu","doi":"10.1016/j.kint.2026.03.013","DOIUrl":"10.1016/j.kint.2026.03.013","url":null,"abstract":"<div><h3>Introduction</h3><div>It is now universally accepted that acute kidney injury (AKI) is not a limited and entirely reversible condition as many previously thought. However, the independent association between mild to moderate AKI and subsequent kidney function trajectory remains poorly characterized because prior studies have not adequately controlled for pre-existing differences between patients who did or did not develop AKI.</div></div><div><h3>Methods</h3><div>Here, we employed linear mixed-effects regression models to examine the association between an episode of AKI and subsequent trajectory of estimated glomerular filtration rate (eGFR), estimated by serum creatinine (eGFRcr) or cystatin C (eGFRcys), among all 1603 participants in the ASsessment, Serial Evaluation, and Subsequent Sequelae of Acute Kidney Injury (ASSESS-AKI) study.</div></div><div><h3>Results</h3><div>In fully adjusted analysis, mild to moderate AKI (83.1% KDIGO Stage 1, 12.2% KDIGO Stage 2) was independently associated with a small magnitude loss of kidney function, i.e., non-recovery to baseline (-1.32 [95% confidence interval, -2.19 to -0.45] ml/min per 1.73 m² for eGFRcr and -1.59 [-2.44 to -0.74] ml/min per 1.73 m² for eGFRcys). There were no statistically significant changes in eGFR slope after AKI (-0.23 [-0.73 to 0.26] ml/min per 1.73 m² per year for eGFRcr slope and -0.25 [-0.74 to 0.23] ml/min per 1.73 m² per year for eGFRcys slope).</div></div><div><h3>Conclusions</h3><div>After pre-AKI eGFR (slope), pre-AKI proteinuria, and other potential confounders were accounted for, the association between mild to moderate AKI and worsening subsequent kidney function was small. Thus, while mild to moderate AKI can be an initiator or promoter of kidney disease progression, the actual magnitude of its clinical and public health importance is likely limited.</div></div>","PeriodicalId":17801,"journal":{"name":"Kidney international","volume":"110 1","pages":"Pages 206-213"},"PeriodicalIF":21.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147743860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}