Journal of Zhejiang University SCIENCE B最新文献

{"title":"Digital mental health: innovations in assessment and intervention.","authors":"Hailong Lyu, Zhaojie Ju, Jianzhong Yang, Shaohua Hu","doi":"10.1631/jzus.B2610003","DOIUrl":"10.1631/jzus.B2610003","url":null,"abstract":"<p><p>Depression and anxiety together are ranked among the leading causes of disability, affecting hundreds of millions of individuals worldwide (GBD 2019 Mental Disorders Collaborators, 2022). Yet, psychiatric care faces persistent structural barriers: limited specialist availability, geographic inequities, diagnostic subjectivity, and the stigma that deters help-seeking behaviors (Patel et al., 2018). Digital technologies, including mobile health platforms, internet-delivered interventions, and artificial intelligence (AI)-driven analytic tools, are beginning to address these constraints by extending the reach and scalability of mental health services (Graham et al., 2019; Torous et al., 2021). This transition was accelerated by the coronavirus disease 2019 (COVID-19) pandemic, as clinicians worldwide adopted remote assessment and teletherapy out of necessity (Wind et al., 2020). The promise of these tools, however, goes beyond crisis response: it not only enables population-level screening but also provides new forms of therapeutic engagement and the discovery of objective diagnostic biomarkers.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 9","pages":"927-932"},"PeriodicalIF":5.7,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive function among COVID-19 survivors in the subacute phase during the epidemic of Omicron variant in China.","authors":"Xue Luo, Shufei Zeng, Shuai Liu, Yuanhui Li, Leqin Fang, Dai Li, Qianqian Xin, Shixu DU, Yan Xu, Bin Zhang","doi":"10.1631/jzus.B2500553","DOIUrl":"10.1631/jzus.B2500553","url":null,"abstract":"<p><p>Following the relaxation of pandemic control measures in China, the impact of coronavirus disease 2019 (COVID-19) on cognitive function in the Chinese population has not been investigated. Therefore, this study aimed to assess cognitive function and identify its risk factors in the subacute phase (<3 months) of COVID-19 patients during the epidemic wave of the Omicron variant. In this nationwide smartphone-based online assessment from January 15 to 29, 2023, the Integrated Cognitive Assessment (ICA) and the Number Ordering Test (NOT) were used to assess cognitive function. Among the 9663 participants, 8905 (92.2%) were COVID-19 survivors. These patients performed poorly on most neuropsychological results (<i>P</i><0.05); however, after controlling for socio-demographics, only the ICA accuracies were lower (<i>P</i><0.05, partial <i>η</i>²≤0.001). After the initial recovery, 5832 (65.5%) COVID-19 survivors reported inflexible thinking, 5419 (60.9%) noted slowed information processing speed, and 4344 (48.8%) reported insomnia. Female sex, older age, low education level, living in Northwest China, and insomnia were significantly associated with poor performance on the key neuropsychological results (range, absolute <i>β</i> values 0.023‒0.430, <i>P</i><0.05). In the subacute phase of COVID-19, subjective cognitive complaints were highly prevalent, whereas objective cognitive differences were subtle. Despite the mild overall impact, vulnerable subgroups-such as females, older adults, individuals with low education level, and patients with insomnia-showed greater susceptibility to these cognitive changes.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 9","pages":"961-977"},"PeriodicalIF":5.7,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional face reconstruction for emotional dynamics: a novel approach to distinguishing bipolar disorder from major depressive disorder.","authors":"Tao DU, Jinchao Ge, Hong Lyu, Yutong Zhang, Xin Xu, Shaohua Hu, Jingkai Chen","doi":"10.1631/jzus.B2500705","DOIUrl":"10.1631/jzus.B2500705","url":null,"abstract":"<p><p>Major depressive disorder (MDD) and bipolar disorder (BD) are frequently misdiagnosed in clinical practice due to their overlapping symptoms, resulting in delayed treatment and an increased burden on patients. Reliable biomarkers for early differential diagnosis are currently lacking. To address this, we developed a clinical facial video dataset of patients with BD and MDD and introduced an adaptive-shape vision-to-language model (AsmV2L), a vision-language-guided fine-grained three-dimensional (3D) face reconstruction framework that better preserves affect-related facial cues from monocular videos. Using valence-arousal (VA) representations estimated from these reconstructed 3D faces, we identified distinct affective patterns that differentiated the two disorders. In the subject-level downstream evaluation, the emotional dynamic features extracted by our framework achieved 88.9% accuracy in distinguishing BD from MDD. Additionally, experiments on public benchmark datasets demonstrated that AsmV2L maintained competitive 3D reconstruction accuracy while preserving emotion-related semantic information more effectively.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 9","pages":"946-960"},"PeriodicalIF":5.7,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic alliance across delivery modalities: a systematic narrative review of alliance strength and outcome prediction in face-to-face, online, and blended psychotherapy.","authors":"Xiaoyi Zhou, Huimin Huang, Ruoxu Bi, Lena Verdeli, Hailong Lyu","doi":"10.1631/jzus.B2500701","DOIUrl":"10.1631/jzus.B2500701","url":null,"abstract":"<p><p>The frequency of online psychotherapy, including pure online (PO: videoconference [PO-VC], telephone [PO-TEL], asynchronous therapist-guided [PO-Async]), or blended (BLD) modalities, has grown exponentially, yet how the therapeutic alliance (TA), a key outcome predictor, compares across these formats and face-to-face (FTF) treatment remains unclear. To compare the TA strength and the TA‒outcome association across FTF, PO, and BLD modalities, a systematic narrative review (Preferred Reporting Items for Systematic Reviews and Meta-Analyses/Synthesis Without Meta-analysis [PRISMA/SWiM]) was performed by searching PubMed, PsycARTICLES, and Web of Science. Studies were deemed eligible if they quantitatively compared TA across at least two modalities in adults with depressive or anxiety disorders. PO arms were classified as telepsychotherapy (PO-VC/TEL) or therapist-guided digital interventions (PO-Async). The findings were synthesized by direction and consistency. Nine studies, including three primary randomized controlled trials (RCTs) and six secondary analyses, were finally included in this study. TA strength was broadly comparable across all three modalities. One study found significantly lower patient-rated working alliance inventory (WAI) scores at Week 2 in PO-Async versus FTF, resolving by Week 8. The TA‒outcome association was mixed, varying by modality, rater perspective, and timepoint. The results showed that TA was broadly equivalent across FTF, PO, and BLD formats, although asynchronous PO might show a transient week-2 lag. The TA‒outcome association was less consistent in PO/BLD than in FTF. As a preliminary hypothesis, digital delivery may shift the functional emphasis of the alliance from affective bonding toward task/goal engagement.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 9","pages":"932-945"},"PeriodicalIF":5.7,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and application of a novel TaqMan qPCR assay targeting the <i>gN</i> gene for genotyping pseudorabies virus.","authors":"Yulan Jin, Xuan Ji, Weiren Dong, Yanming Huang, Jiyong Zhou, Jinyan Gu","doi":"10.1631/jzus.B2500729","DOIUrl":"https://doi.org/10.1631/jzus.B2500729","url":null,"abstract":"<p><p>Pseudorabies virus (PRV), known as porcine herpesvirus type I, belongs to the α-herpesvirus subfamily of the herpesviridae family. Its virions are oval or round, with a genome of approximately 143 000 bp and a high guanine-cytosine (GC) content of 73% (Pomeranz et al., 2005). While swine are the natural host and the virus has caused significant economic loss to the pig industry, PRV can infect other mammals, causing acute infectious diseases characterized by neurological symptoms (He et al., 2019; Cheng et al., 2020). Young pigs are more susceptible to PRV and the infection in piglets is nearly 100% fatal, whereas adult pigs exhibit reproductive disorders such as abortion, stillbirths, and reduced fertility, ultimately decreasing farm productivity (Zuckermann, 2000). Due to its global impact, PRV is classified as a Class B infectious disease by the World Organization for Animal Health (WOAH).</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 8","pages":"923-926"},"PeriodicalIF":5.7,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13474196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced nerve growth factor (NGF) mediates arsenic-induced mitochondrial dynamics imbalance and neuronal damage both in vivo and in vitro.","authors":"Xinbo Ma, Liu Yang, Xinhua Shao, Jia Cui, Ziqiao Guan, Man Lyu, Shuaifei Yang, Na Fang, Yang Liu, Yanhui Gao, Xiaona Liu, Yanmei Yang","doi":"10.1631/jzus.B2500216","DOIUrl":"10.1631/jzus.B2500216","url":null,"abstract":"<p><p>Arsenic exposure is known to cause cognitive deficits, although the underlying mechanisms are yet to be explored. In this study, we investigated the role of nerve growth factor (NGF), a neuroprotective factor, in arsenic-induced cognitive impairment. In mouse models exposed to 25 and 50 mg/L sodium arsenite (NaAsO₂), we observed neuronal damage accompanied by the downregulation of NGF, decreased phosphorylation of phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT), reduced phosphorylation of the mitochondrial fission protein dynamin-related protein 1 (Drp1), and downregulation of the mitochondrial fusion protein optic atrophy 1 (OPA1). Similarly, the downregulation of NGF, inactivation of the PI3K/AKT signaling pathway, mitochondrial dynamics imbalance (dysregulation of mitochondrial fission and fusion processes), and increased apoptosis were observed in HT-22 cells exposed to 4 μmol/L NaAsO₂. NGF overexpression mitigated these arsenic-induced alterations, while the protective effect of NGF against arsenic toxicity was reduced by LY294002, a PI3K/AKT pathway inhibitor. These findings suggest that a decrease in NGF mediates the arsenic-disrupted mitochondrial dynamics via inhibiting the PI3K/AKT pathway, ultimately impairing cognitive function.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 9","pages":"1013-1030"},"PeriodicalIF":5.7,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Programmable DNAzyme nanocatalysts for tumor immunometabolic modulation.","authors":"Rongping Luo, Zhuojia Tang, Mengqi Ding, Lingxiu Zou, Xiaojing Liu, Fan Yin, Jianxin Lyu, Lu Wang","doi":"10.1631/jzus.B2500764","DOIUrl":"10.1631/jzus.B2500764","url":null,"abstract":"<p><p>Programmable RNA-cleaving DNAzymes (RCDs) represent a unique class of catalytic nucleic acids that couple molecular recognition with enzyme-like activity. While DNAzymes have traditionally been explored for targeted gene regulation, recent advances in nanotechnology have repositioned them as programmable biosensing modules with stimuli-responsive therapeutic potential. When integrated into metal-oxide scaffolds, DNA-framework architectures, or metal-organic frameworks, DNAzymes form hybrid platforms that create confined catalytic microenvironments, provide enriched cofactor availability, and facilitate microenvironment-responsive activation. These engineered systems can function as nanoscale biosensing modules that respond to pH, redox gradients, metal ions, or microRNA signatures and convert these biological cues into catalytic outputs. Beyond enhancing analytical performance, such platforms may also reshape tumor immunometabolism. Through the selective cleavage of metabolic or immune-regulatory transcripts, DNAzyme nanocatalysts can directly reprogram glycolysis, redox balance, oxygen tension, and mitochondrial activity, and these metabolic changes in turn alleviate immunosuppression and promote innate and adaptive immune activation. This review outlines the mechanistic foundations of DNAzyme catalysis, summarizes recent nanoengineering strategies that endow DNAzymes with programmable sensing and stimuli-responsive functions, and discusses how these systems bridge biosensing and catalytic immunometabolic functions. We conclude with perspectives on translational challenges and opportunities, endorsing programmable DNAzyme nanocatalysts as emerging preclinical platforms for biosensing-guided immunometabolic intervention.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 7","pages":"698-714"},"PeriodicalIF":5.7,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13420506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA-based one-pot rapid biosensing platform integrating turn-back loop primer-accelerated LAMP and <i>Pyrococcus furiosus</i> Argonaute for meat visual authentication.","authors":"Sheng Ding, Jing Li, Minglong Yang, Yujia Song, Xiangke Niu, Mei Li, Yao Luo","doi":"10.1631/jzus.B2500745","DOIUrl":"10.1631/jzus.B2500745","url":null,"abstract":"<p><p>Meat adulteration is a significant global food safety challenge, creating a pressing need for rapid and on-site detection technologies. Herein, we present an intelligent one-pot biosensing platform termed one-pot TLAMP-PfAgo assay (OTPA) that integrates the rapid amplification of turn-back loop primer-accelerated loop-mediated isothermal amplification (LAMP) (TLAMP) with the sequence-specific detection of <i>Pyrococcus furiosus</i> Argonaute (PfAgo). This system features a clever heat-activatable design using microcrystalline wax to spatially separate reactions within a single tube, enabling contamination-free and streamlined operation. The OTPA assay achieves sensitive and specific detection, with limits of detection as low as 3×10^-4 ng/μL for pork DNA and 2×10^-4 ng/μL for beef DNA within 30 min. It successfully enables duplex target identification and has been validated with commercial meat products, showing perfect concordance with standard polymerase chain reaction (PCR)-based qualitative detection. Notably, the result can be directly visualized under blue light, underscoring the substantial potential of this cost-effective and simple platform for point-of-care testing (POCT) and intelligent biosensing in food safety surveillance.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 7","pages":"775-787"},"PeriodicalIF":5.7,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13420514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood‒brain barrier permeability assessment: from biomimetic models to multimodal imaging.","authors":"Miaomiao Wang, Lu Gan, Yiru Fan, Chenxi Duan, Ying Zhu, Shihua Luo, Yanhong Sun","doi":"10.1631/jzus.B2500786","DOIUrl":"10.1631/jzus.B2500786","url":null,"abstract":"<p><p>The blood‒brain barrier (BBB) is a vital physiological structure that maintains the microenvironmental homeostasis in the central nervous system (CNS). Imbalances in its permeability play a key role in various neurological disorders, including stroke, neurodegenerative diseases, and brain tumors. The development of precise techniques for assessing BBB permeability is therefore paramount for elucidating the mechanisms of neurological diseases, overcoming drug development challenges, and achieving precise diagnosis and treatment of CNS disorders. This review systematically summarizes the latest advances in the assessment of BBB permeability. Regarding in vitro models, platforms have evolved from the traditional transwell system to microfluidic chips incorporating fluid shear forces and subsequently to highly biomimetic brain organoids, with continuous improvements in the ability to simulate the neurovascular unit (NVU) microenvironment. For in vivo assessment, we detail the principles and applications of imaging techniques, including dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), positron emission tomography (PET), near-infrared II (NIR-II) fluorescence imaging (FI), and two-photon microscopy (TPM), highlighting their complementary strengths in macroscopic quantification, molecular targeting, and microscopic dynamic observation. The integration of multi-modal technologies and precise quantitative assessment is a prominent trend. Future investigations will focus on artificial intelligence (AI)-driven personalized permeability assessment, the development of novel intelligent probes, and the dynamic real-time monitoring of the BBB, thereby providing powerful methodological support for neurological disease research.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 7","pages":"715-735"},"PeriodicalIF":5.7,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13420525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenocystine-based fluorescence assay combined with structural prediction for functional analysis of cystine transporter variants in cystinuria.","authors":"Xiaobai He, Xinyi Qian, Xiaoguang Zheng, Hong Zhang, Jinbang Shao, Xiaopan Chen, Qi Ruan, Jianxin Lyu, Leixiang Yang, Linjie Chen","doi":"10.1631/jzus.B2500767","DOIUrl":"10.1631/jzus.B2500767","url":null,"abstract":"<p><strong>Objectives: </strong>Cystine stones account for 1%‒2% of adult and up to 10% of pediatric kidney stones. They result from cystinuria, an autosomal recessive disorder caused by mutations in solute carrier family 3 member 1 (<i>SLC3A1</i>) and <i>SLC7A9</i>, which encode the renal cystine transporter subunits. These mutations impair cystine reabsorption, raising urinary cystine levels and driving stone formation. Current diagnostic options remain limited in terms of detecting molecular dysfunctions. Thus, we aimed to develop a nonradioactive, cell-based method for the functional assessment of cystine transporters and mutation-specific pathologies.</p><p><strong>Methods: </strong>Using human embryonic kidney 293 (HEK293) cells transiently co-expressing wild-type or mutant <i>SLC3A1</i> and <i>SLC7A9</i>, we developed an integrated approach that combined a selenocystine-based fluorescence uptake assay with AlphaFold3-based structural predictions to rapidly and accurately assess cystine transporter function and the molecular impact of genetic mutations.</p><p><strong>Results: </strong>The affinity of the SLC3A1/SLC7A9 complex was comparably apparent for selenocystine (Michaelis constant <i>K</i>_m=(156.3±24.2) μmol/L) and cystine (literature <i>K</i>_m approximately 200 μmol/L). Using operational thresholds (mild >60%, moderate 20%‒60%, severe <20% residual activity), the assay differentiated the functional impacts of eight clinically characterized variants, including <i>SLC7A9</i> A70V, A182T, G105R, R333W, V170M, A354T, and P482L, and <i>SLC3A1</i> M467T, with categorical assignments consistent with previously published radioisotope-based functional data. AlphaFold3 modeling, combined with molecular docking, provides mechanistic interpretations of the dysfunction observed in the P482L and A354T mutants.</p><p><strong>Conclusions: </strong>The integrated approach employed in this work, which combines a sensitive selenocystine fluorescence assay with artificial intelligence (AI)-powered structural analysis, enables the rapid, precise diagnosis of cystinuria variants. This platform is compatible with standard microplate-reader infrastructure and offers potential utility in variant-interpretation pipelines and future genotype-guided therapeutic decision-making, pending prospective clinical validation.</p>","PeriodicalId":17797,"journal":{"name":"Journal of Zhejiang University SCIENCE B","volume":"27 7","pages":"806-816"},"PeriodicalIF":5.7,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13420517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}