Kidney International Reports最新文献

{"title":"Anti-Rituximab Antibodies in Primary Membranous Nephropathy: Time for Routine Monitoring in Clinical Practice?","authors":"Stathis Tsiakas , Stephanie Torres Rodriguez","doi":"10.1016/j.ekir.2025.06.033","DOIUrl":"10.1016/j.ekir.2025.06.033","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2545-2547"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and Limitations in Utilization of Continuous Renal Replacement Therapies in Public Sector Hospitals-Perspective from India","authors":"Manjusha Yadla , Priyadarshini John","doi":"10.1016/j.ekir.2025.06.009","DOIUrl":"10.1016/j.ekir.2025.06.009","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2520-2523"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Improved Diagnosis and Treatment on Holistic CKD Burden","authors":"Navdeep Tangri ,&nbsp;Stacey Priest ,&nbsp;Anthony Zara ,&nbsp;Bo Ren Long ,&nbsp;Jieling Chen ,&nbsp;Naveen Rao ,&nbsp;Clélia-Elsa Froguel ,&nbsp;Breonny Robson ,&nbsp;Nick Guldemond ,&nbsp;Matthew Eckelman ,&nbsp;Ana Flavia Moura ,&nbsp;Ralph Audehm ,&nbsp;Fiona Adshead ,&nbsp;Ming-hui Zhao ,&nbsp;Christoph Wanner ,&nbsp;Steven Chadban","doi":"10.1016/j.ekir.2025.05.039","DOIUrl":"10.1016/j.ekir.2025.05.039","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic kidney disease (CKD) is an underdiagnosed and undertreated disease despite the availability of effective interventions. The potential clinical, economic, and environmental impacts of increased diagnosis and improved adherence to guideline-directed medical therapies (GDMTs) recommended for patients with CKD are not well-understood.</div></div><div><h3>Methods</h3><div>Eight country populations (Australia, Brazil, China, Germany, The Netherlands, Spain, UK, and USA) were simulated for 25 years using the IMPACT CKD model to compare burdens under various diagnosis and GDMT adherence scenarios versus current practice. GDMT consisted of kidney protecting, glucose lowering, lipid lowering, as well as antihypertensive and lifestyle interventions. Patients could be treated with 1 or multiple therapies, if eligible, and no guideline changes occurred over the time horizon. Treatment effects were assumed multiplicative.</div></div><div><h3>Results</h3><div>Scenarios with improved GDMT adherence projected cumulative decreases in dialysis, cardiovascular (CV) events, and death by −3.2% to −23.2%, −12.2% to −41.4%, and −2.3% to −9.3%, respectively, compared with current practice over 10 years. Because of delayed CKD progression, kidney replacement therapy (KRT) costs and environmental burden were also projected to decrease by −2.5% to −19.4% and −2.7% to −21.2%, respectively, compared with current practice. All treatment scenarios predicted greater improvements over 25 years, underscoring the long-term impact of CKD, and highlighting the importance of early intervention.</div></div><div><h3>Conclusion</h3><div>Differences in projected impacts between countries are multifactorial, though they are sensitive to demographics and health care systems. Implementation of policies that lead to improved detection and treatment of CKD are urgently required across the globe to mitigate the growing burdens of CKD on patients and caregivers, health care systems, society, and our environment.</div></div>","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2608-2620"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obinutuzumab in Rituximab-Resistant Podocytopathies: A Single-Center Experience","authors":"Andrea Angeletti ,&nbsp;Gianluca Caridi ,&nbsp;Xhuliana Kajana ,&nbsp;Carolina Bigatti ,&nbsp;Agnese Spennacchio ,&nbsp;Decimo Silvio Chiarenza ,&nbsp;Gabriele Mortari ,&nbsp;Paolo Cravedi ,&nbsp;Enrico E. Verrina","doi":"10.1016/j.ekir.2025.06.019","DOIUrl":"10.1016/j.ekir.2025.06.019","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2873-2874"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat Exposure and Short-Term Changes in Kidney Biomarkers: Answers to the CKD of Unknown Etiology Conundrum?","authors":"Eranga Wijewickrama ,&nbsp;Ben Caplin","doi":"10.1016/j.ekir.2025.06.011","DOIUrl":"10.1016/j.ekir.2025.06.011","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2527-2529"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Discordant Estimated GFR Among Adults in a Community-Based Population","authors":"Wei Wang ,&nbsp;Xiufang Kong ,&nbsp;Xue Li ,&nbsp;Junan Wu","doi":"10.1016/j.ekir.2025.05.053","DOIUrl":"10.1016/j.ekir.2025.05.053","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2883-2884"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not All IgA Nephropathy are the Same: Clinical Implications of Recurrent Versus de novo Disease Posttransplant","authors":"Mythri Shankar ,&nbsp;Nada Alachkar","doi":"10.1016/j.ekir.2025.06.001","DOIUrl":"10.1016/j.ekir.2025.06.001","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2539-2541"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperthermia Predicts Cross-Shift Acute Kidney Injury Risk in Construction Workers","authors":"Erica Tourula ,&nbsp;Jonathan W. Specht ,&nbsp;M. Jo Hite ,&nbsp;Charlie Walker ,&nbsp;Serena Garcia ,&nbsp;Omkar Khandpekar ,&nbsp;Hillary A. Yoder ,&nbsp;Roger S. Zoh ,&nbsp;Blair D. Johnson ,&nbsp;David H. Wegman ,&nbsp;Jason Glaser ,&nbsp;Fabiano Amorim ,&nbsp;Zachary J. Schlader","doi":"10.1016/j.ekir.2025.05.044","DOIUrl":"10.1016/j.ekir.2025.05.044","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2856-2859"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Lactate Levels and Kinetics Predict Citrate Accumulation in Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy","authors":"Harmony Hau Man To ,&nbsp;Arthur Ming Chit Kwan ,&nbsp;Natalie Yat Yee Leung ,&nbsp;Felix Chi Kin Wong ,&nbsp;Wai Ming Chan ,&nbsp;Chun Wai Ngai ,&nbsp;Alfred Sai Kuen Wong ,&nbsp;Polly Nga Wing Tsai ,&nbsp;Tammy Sin Kwan Ma ,&nbsp;Irene Yam ,&nbsp;Pauline Yeung Ng ,&nbsp;Desmond Yat Hin Yap","doi":"10.1016/j.ekir.2025.05.038","DOIUrl":"10.1016/j.ekir.2025.05.038","url":null,"abstract":"","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2852-2855"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kidney Disease: Improving Global Outcomes Summit Recommendations on Implementation of Diabetes Management in CKD: From Primary to Data-Driven Collaborative Care","authors":"Philip Kam-Tao Li ,&nbsp;Michael Cheung ,&nbsp;Kai-Ming Chow ,&nbsp;Maria Kwan Wa Leung ,&nbsp;Lee-Ling Lim ,&nbsp;Juliana N.M. Lui ,&nbsp;Andrea O.Y. Luk ,&nbsp;Jo-Anne Manski-Nankervis ,&nbsp;Samuel Seidu ,&nbsp;Nikhil Tandon ,&nbsp;Adrian Liew ,&nbsp;Peter Lin ,&nbsp;Fei Chau Pang ,&nbsp;Na Tian ,&nbsp;Kohjiro Ueki ,&nbsp;Martin C.S. Wong ,&nbsp;Sophia Zoungas ,&nbsp;Kit Man Loo ,&nbsp;Kin Lai Chung ,&nbsp;Victor Hin-Fai Hung ,&nbsp;Juliana C.N. Chan","doi":"10.1016/j.ekir.2025.06.010","DOIUrl":"10.1016/j.ekir.2025.06.010","url":null,"abstract":"<div><div>Type 2 diabetes and chronic kidney disease (CKD) are preventable and treatable. Their silent and progressive clinical course calls for structured assessment with timely feedback to patients and care providers for activating decision-making. Apart from CKD, patients with diabetes can have complications affecting multiple organs, notably the cardiovascular system, eyes, and feet. International practice guidelines recommend annual assessment of the eyes, feet, blood, and urine to detect silent complications and measure cardiovascular-kidney-metabolic (CKM) risk factors to ensure early intervention, including treatment to multiple targets and use of organ-protective drugs. In this report, we highlight the barriers and gaps in the implementation of practice guidelines in managing diabetes in CKD with proposed solutions to overcome such barriers. By improving the practice environment and workflow, nurses can be trained to perform protocol-guided evaluation under medical supervision. The systematic data collection enables physicians to make timely decisions, including drug prescriptions and referrals to other specialists to promote collaborative care, whereas nurses can use the personalized data to empower patient self-management and improve health literacy. This ongoing data collection will form a register to align payers, providers, and patients in delivering data-driven and value-based care with the creation of real-world evidence to verify treatment effectiveness and identify care gaps while providing on-the-job training. When accompanied by a biobank, the ongoing collection and analysis of this multidimensional data will refine diagnosis, classification, prognosis, and treatment in pursuit of precision medicine.</div></div>","PeriodicalId":17761,"journal":{"name":"Kidney International Reports","volume":"10 8","pages":"Pages 2551-2565"},"PeriodicalIF":5.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}