Jurnal Farmasi Sains dan Praktis最新文献_第6页

STANDARDIZATION OF SECONDARY METABOLITES AND HEAVY METAL CONTAMINATION ASSAY ON ONCHIDIID SLUG (ONCHIDIUM TYPHAE) WEST KALIMANTAN WATERS 西加里曼丹水域牙鲆次生代谢物标准化及重金属污染测定

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-10-31 DOI: 10.31603/pharmacy.v8i3.7296

B. Wijianto, A. Nurhidayah, Sri Luliana

引用次数: 2

EVALUATION OF RESPONSE CORELLATION USING CHEMOMETRICS ANALYSIS FOR PRE-OPTIMIZATION QUERCETIN – SELF EMULSION FORMULATION 应用化学计学分析评价槲皮素自乳化制剂的反应相关性

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6660

S. Shiyan, Jessica Nathasia, Galih Pratiwi

{"title":"EVALUATION OF RESPONSE CORELLATION USING CHEMOMETRICS ANALYSIS FOR PRE-OPTIMIZATION QUERCETIN – SELF EMULSION FORMULATION","authors":"S. Shiyan, Jessica Nathasia, Galih Pratiwi","doi":"10.31603/pharmacy.v8i2.6660","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i2.6660","url":null,"abstract":"The optimization approach using the simplex lattice design (SCD) has many advantages, including a minimized number of experiments and a good description of the interactions between components. However, modeling with the SCD approach has not evaluated between responses. Therefore, this study aims to apply chemometric analysis to evaluate the response from the optimization stage using the quercetin – self emulsion formulations (quercetin-SEFs) as a model. SEFs were prepared using grapeseed oil, croduret, and PEG 400. The evaluated responses included emulsification time and transmittance. Both responses were developed in endurance test by centrifugation method and stability test using freeze-thaw. Chemometric analysis on CA produced a dendrogram, while PCA produced score plots, loading plots, scree plots, and biplots. Emulsification time has a positive correlation with transmittance value. The quercetin-SEFs formula in SCD was classified into three groups based on the similarity of characters. Chemometric analysis was successfully applied in evaluating the response to the quercetin-SEFs optimization modeling.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42674429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EFFECT OF BETEL LEAF EXTRACT SPRAY ON HISTOPATHOLOGY OF WOUND HEALING 槟榔叶提取物喷雾对创面愈合组织病理学的影响

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6902

L. H. Nurani, I. M. Sikumbang, S. Yuliani, Citra Aryani Edityaningrum

引用次数: 0

EFFECT OF GELATIN AS A BINDER ON TURMERIC EXTRACT TABLET FORMULATION 明胶粘结剂对姜黄浸膏片剂配方的影响

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6399

Adidiya Permadi, Iis Wahyuningsih, S. Yuliani, Ibdal Satar, Ratna Wijayatri

引用次数: 1

STABILITY AND SUNSCREEN ACTIVITY OF NUTMEG SEED OIL EMULGEL WITH CARBOPOL 940 VARIATION AS GEL BASE 以卡波醇940变异为凝胶基的肉豆蔻籽油乳液的稳定性和防晒活性

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6085

Ilma Nur Khafifa, Ayu Shabrina, M. F. Rochman

{"title":"STABILITY AND SUNSCREEN ACTIVITY OF NUTMEG SEED OIL EMULGEL WITH CARBOPOL 940 VARIATION AS GEL BASE","authors":"Ilma Nur Khafifa, Ayu Shabrina, M. F. Rochman","doi":"10.31603/pharmacy.v8i2.6085","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i2.6085","url":null,"abstract":"Nutmeg seed oil is one of essential oil which unstable in storage. The stability of nutmeg seed oil can be improved by being formulated into an emulgel with carbopol 940. This study was to determine the physical stability and SPF value of nutmeg oil emulgel in vitro with carbopol 940 as a gel base. Nutmeg seed oil emulgel was made with 10% nutmeg seed oil concentration and variation of carbopol 940 base, namely 0.60% (FI), 0.80% (FII), and 1.0% (FIII). Nutmeg seed oil emulgel was tested for physical stability including organoleptic, homogeneity, adhesion, dispersibility, viscosity, pH, and SPF value in vitro. Evaluation of physical stability and SPF value of nutmeg oil emulgel was carried out for 30 days of storage at 30±2°C with RH 65±5%. Quantitative data from evaluation of physical stability and SPF value were analyzed by t-test dependent. All the physical parameters showed no significant changes (p > 0.05). Emulgel were white, thick, with nutmeg seed oil odor. pH were in safe range for skin (6.12-6.90). Nutmeg seed oil emulgel had pseudo plastic rheology in day 0 and it changed into pseudoplastic-tixothropic on day 30. The SPF value of nutmeg seed oil emulgel FI, FII, and FIII were above 8 and it did not showed significant change after 30 days of storage (p > 0.05). The SPF value of nutmeg seed oil emulgel were categorized as maximum protection.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45107135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

DETERMINATION OF TOTAL FLAVONOID IN JAMU “X” WITH UV-VISIBLE SPECTROPHOTOMETRIC METHODS 紫外可见分光光度法测定加木x中总黄酮含量

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6864

Perdana Priya Haresmita, Missya Putri Kurnia Pradani

{"title":"DETERMINATION OF TOTAL FLAVONOID IN JAMU “X” WITH UV-VISIBLE SPECTROPHOTOMETRIC METHODS","authors":"Perdana Priya Haresmita, Missya Putri Kurnia Pradani","doi":"10.31603/pharmacy.v8i2.6864","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i2.6864","url":null,"abstract":"Jamu is still the choice of Indonesian people as an alternative to modern medicine until now. As a cultural heritage of the Indonesian, jamu is still very popular from the west to the east of Indonesia. The enthusiasm of the Indonesian in consuming jamu has encouraged many traditional medicine industries to produce jamu with many kinds of claim. Jamu \"X\" is claimed to help maintain body health. This research was conducted to determine the total flavonoid content in jamu \"X\" calculated as rutin by UV-spectrophotometric method with aluminum chloride (AlCl3) reagent. Jamu \"X\" is a product with new formula that is expected to be marketed soon. The determination of the maximum absorbance wavelength of rutin was carried out at a wavelength of 400-800 nm and the resulting maximum absorbance wavelength of rutin was 416.5 nm. The determination of total flavonoid calculated as rutin determined using a linear regression equation from the rutin standard. The linear regression equation was determined from a rutin standard curve series with 10; 12.5; 15; 17.5 and 20 g/ml, respectively and the linear regression equation obtained y = 0.0275x + 0.093. The results of the determination of rutin in the jamu \"X\" were 1.474%; 1.474% and 1.469% with an average value of 1.472%.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42092123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

SOME NATURAL FLAVONOIDS FROM GUAVA (PSIDIUM GUAJAVA L.) AGAINST SARS COV-2, INSILICO PREDICTION AND DRUGS EVALUATION 番石榴中的一些天然类黄酮(psidium guajava l .)针对SARS - cov-2的计算机预测及药物评价

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.6441

Arief Kusuma Wardani

引用次数: 0

THE INFLUENCES OF KNOWLEDGE LEVEL BEHAVIOUR AND ATTITUDE IN SELECTING TYPE OF POWDER ON THE INCIDENCE OF ACNE VULGARIS IN BANYUMAS REGENCY 知识水平、行为及爽身粉选择态度对常见性痤疮发病率的影响

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-06-30 DOI: 10.31603/pharmacy.v8i2.4668

Anggita Nur Fauzana, I. Hapsari, Irsalina Nurul Putri, Githa Fungie Galistiani

{"title":"THE INFLUENCES OF KNOWLEDGE LEVEL BEHAVIOUR AND ATTITUDE IN SELECTING TYPE OF POWDER ON THE INCIDENCE OF ACNE VULGARIS IN BANYUMAS REGENCY","authors":"Anggita Nur Fauzana, I. Hapsari, Irsalina Nurul Putri, Githa Fungie Galistiani","doi":"10.31603/pharmacy.v8i2.4668","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i2.4668","url":null,"abstract":"Background: Acne vulgaris is a chronic obstructive and inflammatory skin disease. It occurs in almost all adolescents with a prevalence of 90%. Pathogenesis of Acne vulgaris is estimated to be related to several triggering factors such as food by 23.2%, stress by 26.4%, hormones by 32.7% and use of cosmetics by 47.3%. Powder is the most widely used cosmetic in the long term and one of the causes of Acne vulgaris which causes occlusion of pores on the skin surface. In the content of powder that causes acne vulgaris because there are comedogenic ingredients such as lanolin. Methods: This study was an observational study with data collection techniques using cluster sampling and sampling technique by accidental sampling. Results: The level of knowledge of women in the Banyumas Regency was dominated by the high category as many as 64 respondents (64.0%). The incidence of acne vulgaris out of 100 respondents, 67 (67.0%) of respondents had mild acne vulgaris, 22 respondents (22.0%) had moderate acne vulgaris and 1 respondent (1.0%) had severe acne vulgaris and the rest had no acne vulgaris. Chi-square analysis showed that there was a relationship between knowledge with behavior and attitude in choosing the type of powder to the incidence of acne vulgaris as evidenced by the p value of each variable, namely 0.044 and 0.028 (p <0.05). Conclusion: the level of knowledge with behavior and attitude in choosing the powder type had a significant relationship to the incidence of acne vulgaris in women in Banyumas Regency.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42025300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EVALUATION OF ANTI-EPILEPTIC DRUGS DOSAGE IN MALNOURISHED CHILDREN: CASES IN INDONESIAN COMMUNITY OF EPILEPSY 营养不良儿童抗癫痫药物剂量评价:印度尼西亚癫痫社区病例

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.4662

N. E. Endriastuti, M. W. Suryoputri, D. L. Ilma

{"title":"THE EVALUATION OF ANTI-EPILEPTIC DRUGS DOSAGE IN MALNOURISHED CHILDREN: CASES IN INDONESIAN COMMUNITY OF EPILEPSY","authors":"N. E. Endriastuti, M. W. Suryoputri, D. L. Ilma","doi":"10.31603/pharmacy.v8i1.4662","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.4662","url":null,"abstract":"Anti-epileptic drug (AED) has a narrow therapeutic index of drugs that a slight increase in dosage showed toxic effects. The therapeutic response is difficult to predict in malnutrition status because the patient with nutritional deficiency have more complicated problems likes hypoalbuminemia, macronutrient and micronutrients deficiency that affected the levels of AEDs. The nutritional deficiency could be a direct and indirect cause of ineffective AEDs therapy and also recurrent epilepsy. This study aims to describe the use of antiepileptic drugs in Indonesian children with poor nutritional status. The research design was observational studies with cross sectional random sampling to evaluate the AED doses of malnutrition status in children. All information was collected by spreading electronic forms and interviewing the parents by phone. The data were analyzed descriptively. Total of 8 malnourished children mostly included in the range of ages from >2 to 12 years (n=5; 62.50%) with means 3,9±2,7 years. The study showed valproic acid was bigger used in monotherapy (n=5; 62,50%) than polytherapy with carbamazepine or sodium phenytoin and phenobarbital. The means estimation of valproic acid monotherapy concentration in females’ group (n=2; 33,33%) showed sub-therapeutics level were Cssmin 26,09±0,57 mg/L and Cssmax 64,17±1,39 mg/L, also the means in males’ group (n=2; 33,33%) of valproic acid monotherapy were Cssmin 22.07±2,71 mg/L and Cssmax 54.27±6.66 mg/L. All of them included in good clinical outcome of free seizure > 6 months.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41778678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IMPROVING PKK CADRES LEVEL OF KNOWLEDGE OF ANTIBIOTIC MANAGEMENT THROUGH PHARMACISTS-DELIVERED EDUCATION INTERVENTION IN BOJONGSARI, BANYUMAS 通过药剂师教育干预来提高PKK干部的抗生素管理知识水平

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.4357

M. W. Suryoputri, H. Ekowati, Ika Mustikaningtias, Nialiana Endah

{"title":"IMPROVING PKK CADRES LEVEL OF KNOWLEDGE OF ANTIBIOTIC MANAGEMENT THROUGH PHARMACISTS-DELIVERED EDUCATION INTERVENTION IN BOJONGSARI, BANYUMAS","authors":"M. W. Suryoputri, H. Ekowati, Ika Mustikaningtias, Nialiana Endah","doi":"10.31603/pharmacy.v8i1.4357","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.4357","url":null,"abstract":"The prevalence of infectious diseases in Indonesia is high, so it can increase the use of antibiotics. The use of antibiotics which is around 40-60%. Inaddition to relatively long antibiotic therapy regimen, the lack of public knowledge in the rational use of antibiotics can cause patients to be less the risk of occurrence of antibiotic resistance, this study aims to determine the level of knowledge of PKK Cadres and to determine the level of community knowledge after providing PKK Cadres education with pharmacist assitance on antibiotic management. PKK cadres are the driving force behind village communities to carry out local health programs. The research method is a comparative descriptive with a cross sectional approach using an instrument in the form of a questionnaire and it is carried out before and after the implementation of pharmacist education. Collecting data by purposive sampling. Knowledge data of pretest and posttest were analyzed bivariately. The results of the evaluation of the education process indicated that there was an increase in the knowledge of PKK Caders. The results of pre-test dan post-test average showed increased of knowledge among PKK cadres from 69.28 to 85. The results of Wilcoxon test showed a significant difference in the PKK cadres level knowledge from the pre-test and post-test data of antibiotic management after receiving education from the pharmacist (p<0.005). Providing education on antibiotic management to PKK cadres by pharmacists has increased PKK cadres’ knowledge of antibiotic management. It is hoped that PKK cadres can disseminate this knowledge to the wider community to preventing antibiotic resistance.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49255532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0