STABILITY AND SUNSCREEN ACTIVITY OF NUTMEG SEED OIL EMULGEL WITH CARBOPOL 940 VARIATION AS GEL BASE

Ilma Nur Khafifa, Ayu Shabrina, M. F. Rochman
{"title":"STABILITY AND SUNSCREEN ACTIVITY OF NUTMEG SEED OIL EMULGEL WITH CARBOPOL 940 VARIATION AS GEL BASE","authors":"Ilma Nur Khafifa, Ayu Shabrina, M. F. Rochman","doi":"10.31603/pharmacy.v8i2.6085","DOIUrl":null,"url":null,"abstract":"Nutmeg seed oil is one of essential oil which unstable in storage. The stability of nutmeg seed oil can be improved by being formulated into an emulgel with carbopol 940. This study was to determine the physical stability and SPF value of nutmeg oil emulgel in vitro with carbopol 940 as a gel base. Nutmeg seed oil emulgel was made with 10% nutmeg seed oil concentration and variation of carbopol 940 base, namely 0.60% (FI), 0.80% (FII), and 1.0% (FIII). Nutmeg seed oil emulgel was tested for physical stability including organoleptic, homogeneity, adhesion, dispersibility, viscosity, pH, and SPF value in vitro. Evaluation of physical stability and SPF value of nutmeg oil emulgel was carried out for 30 days of storage at 30±2°C with RH 65±5%. Quantitative data from evaluation of physical stability and SPF value were analyzed by t-test dependent. All the physical parameters showed no significant changes (p > 0.05). Emulgel were white, thick, with nutmeg seed oil odor. pH were in safe range for skin (6.12-6.90). Nutmeg seed oil emulgel had pseudo plastic rheology in day 0 and it changed into pseudoplastic-tixothropic on day 30.  The SPF value of nutmeg seed oil emulgel FI, FII, and FIII were above 8 and it did not showed significant change after 30 days of storage (p > 0.05). The SPF value of nutmeg seed oil emulgel were categorized as maximum protection.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Farmasi Sains dan Praktis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31603/pharmacy.v8i2.6085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

Nutmeg seed oil is one of essential oil which unstable in storage. The stability of nutmeg seed oil can be improved by being formulated into an emulgel with carbopol 940. This study was to determine the physical stability and SPF value of nutmeg oil emulgel in vitro with carbopol 940 as a gel base. Nutmeg seed oil emulgel was made with 10% nutmeg seed oil concentration and variation of carbopol 940 base, namely 0.60% (FI), 0.80% (FII), and 1.0% (FIII). Nutmeg seed oil emulgel was tested for physical stability including organoleptic, homogeneity, adhesion, dispersibility, viscosity, pH, and SPF value in vitro. Evaluation of physical stability and SPF value of nutmeg oil emulgel was carried out for 30 days of storage at 30±2°C with RH 65±5%. Quantitative data from evaluation of physical stability and SPF value were analyzed by t-test dependent. All the physical parameters showed no significant changes (p > 0.05). Emulgel were white, thick, with nutmeg seed oil odor. pH were in safe range for skin (6.12-6.90). Nutmeg seed oil emulgel had pseudo plastic rheology in day 0 and it changed into pseudoplastic-tixothropic on day 30.  The SPF value of nutmeg seed oil emulgel FI, FII, and FIII were above 8 and it did not showed significant change after 30 days of storage (p > 0.05). The SPF value of nutmeg seed oil emulgel were categorized as maximum protection.
以卡波醇940变异为凝胶基的肉豆蔻籽油乳液的稳定性和防晒活性
肉豆蔻籽油是一种贮藏不稳定的精油。肉豆蔻籽油的稳定性可以通过与carbopol 940配制成乳化凝胶来提高。本研究以卡波姆940为凝胶基质,测定肉豆蔻油乳液的物理稳定性和SPF值。用10%的肉豆蔻籽油浓度和卡波姆940碱的变化,即0.60%(FI)、0.80%(FII)和1.0%(FIII)制备肉豆蔻籽油乳液。在体外测试肉豆蔻籽油乳液的物理稳定性,包括感官、均匀性、粘附性、分散性、粘度、pH值和SPF值。肉豆蔻油乳液的物理稳定性和SPF值的评估是在30±2°C和RH 65±5%的条件下储存30天。物理稳定性评估和SPF值的定量数据通过t检验进行分析。所有物理参数均无显著变化(p>0.05)。乳胶凝胶呈白色,粘稠,有肉豆蔻籽油气味。pH值在皮肤安全范围内(6.12-6.90)。肉豆蔻籽油乳液在第0天具有假塑性流变性,在第30天变为假塑性触变性。肉豆蔻油乳液的SPF值FI、FII和FIII均在8以上,储存30天后没有显著变化(p>0.05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
70
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信