Jurnal Farmasi Sains dan Praktis最新文献_第7页

FORMULATIONS AND PHYSICAL STABILITY TEST OF OLIVE OIL (Olea europaea L.) LIP BALM WITH ILLIPE BUTTER 橄榄油的配方及物理稳定性试验唇膏含有伊利普黄油

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.4977

Rise Desnita, Desy Siska Anastasia, M. Putri

{"title":"FORMULATIONS AND PHYSICAL STABILITY TEST OF OLIVE OIL (Olea europaea L.) LIP BALM WITH ILLIPE BUTTER","authors":"Rise Desnita, Desy Siska Anastasia, M. Putri","doi":"10.31603/pharmacy.v8i1.4977","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.4977","url":null,"abstract":"Lip balm is a preparation that is applied on the lips to protect the lips from damage. Olive oil is an oil that has emollient properties that are able to maintain moisture, flexibility, and smoothness in the skin. Oleic acid content in olive oil has the ability to improve skin permeability. Tengkawang fat is known to have characteristics similar to cocoa fat so it is used as a base. This study will provide an overview of the physical properties of olive oil lip balm (olive oil) with tengkawang fat based on storage for 28 days. Lip balm preparations are made in three concentration variations for 10%, 15%, and 20%, Then the preparation will be observed organoleptically changes, homogeneity of the preparation, pH and temperature of the melting point. The results ANOVA test of pH showed there was no significant difference between storage time to pH for each formula. Organoleptic and homogeneity test show good results in the absence of discoloration, odor, and texture and homogeneity during the storage period. The evaluation of lip balm preparations for each formula showed that the preparations were physically stable during the 28-day storage period.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47195288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SYSTEMATIC REVIEW OF THE USABILITY EVALUATION METHODOLOGY OF HEALTH INFORMATION SYSTEMS 卫生信息系统可用性评价方法的系统审查

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.6625

S. A. Kristina, Rivai Endra Dwi Yulianto, Anna Wahyuni Widayanti

{"title":"SYSTEMATIC REVIEW OF THE USABILITY EVALUATION METHODOLOGY OF HEALTH INFORMATION SYSTEMS","authors":"S. A. Kristina, Rivai Endra Dwi Yulianto, Anna Wahyuni Widayanti","doi":"10.31603/pharmacy.v8i1.6625","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.6625","url":null,"abstract":"A good information system will support the implementation of the tasks and functions of the organization. This systematic review aims to identify and characterize the methods and attributes in usability evaluation and identify measurement techniques in usability evaluation. This systematic review uses the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. The search was carried out using two databases, namely PubMed and Science Direct, by limiting information systems related to health published from 2015 to 2021. Articles that met the criteria were evaluated for methods, attributes, measurement techniques, and usability criteria used. Article quality was assessed using a modified Downs and Black checklist. The search identified 132 articles. The results of abstract screening and duplication-checking obtained 128 articles. The screening was carried out through a complete review of the inclusion and exclusion criteria, obtained 9 articles that met the criteria. There are five methods used for usability evaluation, namely Think aloud (TA), Heuristic evaluation (HE), System Usability Scale (SUS), User viewpoint, and Cognitive Walkthrough Method. Six problem definitions used in usability evaluation are ISO, Nielsen, user-based, TAUCHI, 19 item usability questions, and successful completion of scenarios. The measurement technique is done by qualitative and quantitative analysis. Effectiveness, efficiency, and satisfaction are criteria that are always assessed from almost all articles reviewed. The heuristic evaluation method with quantitative measurement techniques using an evaluator in evaluating usability based on scenarios then proceeding with qualitative measurement techniques to deepen problems and provide solutions is the most ideal usability evaluation measurement technique.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43707456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

FORMULATION OF CHEWABLE TABLET PREPARATIONS FROM THE COMBINATION OF Azadirachta Indica A. Juss. AND Gynura Procumbens (Merr.) 印楝组合可药用片剂的研制。与Gynura Procumbens（Merr.）

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.5918

N. P. Pratama, Kurnia Rahayu Purnomo Sari, E. Kurniawati

{"title":"FORMULATION OF CHEWABLE TABLET PREPARATIONS FROM THE COMBINATION OF Azadirachta Indica A. Juss. AND Gynura Procumbens (Merr.)","authors":"N. P. Pratama, Kurnia Rahayu Purnomo Sari, E. Kurniawati","doi":"10.31603/pharmacy.v8i1.5918","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.5918","url":null,"abstract":"Azadirachta indica A. Juss. and Gynura procumbens (Merr.) are one type of potential medicinal plants because they have various properties. One of the properties of these two plants is as an antioxidant. The combination of the two plants has a strong category of antioxidant activity, does not cause death and physical changes in test animals. This study aimed to make an antioxidant chewable Tablet containing a combination of Azadirachta indica A. Juss. and Gynura procumbens (Merr.) extract with a variation of mannitol-sorbitol as a filler. This variation has the advantage of covering the bitter taste of the active substance so that it is expected to provide a pleasant taste and is easy to swallow. The extract obtained was formulated into chewable Tablets with variations of mannitol-sorbitol (90%:10%), (80%:20%), and (70%:30%). The method used is wet granulation. The granules obtained were tested for their physical properties, namely flow velocity, angle of repose, and compressibility. The physical properties of the Tablets tested included uniformity of weight, size, hardness, friability, disintegration time, quality of taste, shape, and odor. Based on the test results of the physical properties of the granules, the three formulas met the requirements. While the physical properties of Tablets that do not meet the criteria are uniformity of size and disintegration time. This research concludes that the extracts of Azadirachta indica A. Juss. and Gynura procumbens (Merr.) be formulated into chewable Tablets where formula two with variations of mannitol:sorbitol (80:20%) is the best formula by fulfilling 9 of 11 requirements","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46471108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DETERMINATION OF BORAX IN WET NOODLE IN SEPATAN MARKET TANGERANG BY TURMERIC INDICATOR PAPER, FLAME TEST, AND UV-VIS SPECTROPHOTOMETRY 用姜黄指示纸、火焰试验、紫外-可见分光光度法测定柑桔湿面中硼砂的含量

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-30 DOI: 10.31603/pharmacy.v8i1.6931

Rulyta Aulia Munandar, N. Rusdiana, La Ode Akbar Rasydy

引用次数: 1

THE POTENCY OF CUCUMBER (CUCUMIS SATIVUS L.) PEEL EXTRACT AS ANTICHOLESTEROL 黄瓜(cucumis sativus l .)的效力果皮提取物抗胆固醇

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-29 DOI: 10.31603/pharmacy.v8i1.3493

Resita Putri, D. Anggraini

{"title":"THE POTENCY OF CUCUMBER (CUCUMIS SATIVUS L.) PEEL EXTRACT AS ANTICHOLESTEROL","authors":"Resita Putri, D. Anggraini","doi":"10.31603/pharmacy.v8i1.3493","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.3493","url":null,"abstract":"The liver has a very important role in the human body. However, these organ tissues are also very susceptible to be tissue damage. Fatty liver disease (steatosis) is a disease caused by high cholesterol. Physically, cholesterol is a yellowish subtance, lumps like wax, and is an arrangement of steroid groups. Non-alcoholic steatohepatitis (NASH) occurs due to excess cholesterol levels in the liver. Liver function can be affected as a result of liver damage. So, a hepatoprotector is needed. The flavonoid content of cucumber skin has potential as an anticholesterol. The purpose of this research is to analyze the ability of the ethanol extract of cucumber peel (Cucumis sativus L.) as a cholesterol lowering agents as indicated by the EC50 value. Maceration extraction method used in this study using 96% ethanol as solvent. Qualitative analysis of ethanolic extract of cucumber peel is known to have flavonoids, steroids, alkaloids as indicated by the appearance of color changes, and saponins which are indicated by the appearance of foam. Lieberman-burchad reagent was used for quantitative analysis of anticholesterol using a UV-Visible spectrophotometer. The analysis was carried out at a maximum wavelength of 665,0 nm with an incubation time of 15 minutes. The concentration variations of the extract used were between 25-150 with a range of 25 ppm. The results showed that the ethanolic extract of cucumber peel could potentially be an anticholesterol with the percentage reduction of 28.50%; 35.45%; 39.59%; 45.82%; 51.24%; and 55.12% at 5 variations of concentration. The EC50 value was achieved at a concentration of 122.04 ppm. \u0000 ","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46103862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

ANALYSIS BETWEEN THE NUMBER OF ANTIHYPERTENSIVE WITH MEDICATION ADHERENCE IN END STAGE RENAL DISEASE 终末期肾病降压药与药物依从性的关系分析

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-29 DOI: 10.31603/pharmacy.v8i1.5611

Pande Made Desy Ratnasari, Ketut Lia Pran Anggar Yani, Heny Dwi Arini

{"title":"ANALYSIS BETWEEN THE NUMBER OF ANTIHYPERTENSIVE WITH MEDICATION ADHERENCE IN END STAGE RENAL DISEASE","authors":"Pande Made Desy Ratnasari, Ketut Lia Pran Anggar Yani, Heny Dwi Arini","doi":"10.31603/pharmacy.v8i1.5611","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.5611","url":null,"abstract":" \u0000End-Stage Renal Disease (ESRD) is a condition of severe renal damage associated with a higher incidence of hypertension that requires antihypertensive therapy to prevent the worsening disease. Therefore, patients who received more than two types of antihypertensives have affected medication adherence. This study aimed to analyze relationship between the number of antihypertensives and medication adherence in ESRD patients. The study was a cross-sectional design involving 77 participants selected by a purposive sampling technique at Outpatient Private Hospital Buleleng Bali in July-September 2020. Data were collected based on patient’s medical records and the Probabilistic Medication Adherence Scale (ProMAS) questionnaire. The inclusion criteria were ESRD patients aged ≥18 years, with hypertension history, taking the same antihypertensive for three months before the study, sign informed consent, and completed medical record data. Those who were a weak general condition and cognitive impairment were excluded from the study. Data were analyzed using a Kruskal-Wallis test. The results showed that overall, of patients were <65 years old (80.52%), male (70.13%), duration of ESRD <5 years (89.61%), primarily high school (57.14%), and without complications (57.1%). Most patients used a combination of two antihypertensives (35.07%), and 61.04% has a high medication adherence. There was no significant relationship between the number of antihypertensives and medication adherence (p=0.847). Nevertheless, it was still shown that the higher number of antihypertensives in ESRD patients was directly proportional to the lower medication adherence. \u0000 \u0000 ","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47874504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PHYTOCHEMICAL ANALYSIS AND TOTAL FLAVONOID CONTENT ON ETHANOL AND ETHYL ACETATE EXTRACT FROM NEEM (AZADIRACHTA INDICA JUSS.) LEAVES UTILIZING UV–VIS SPECTROPHOTOMETRIC 印楝叶乙醇和乙酸乙酯提取物的紫外-可见光谱分析及总黄酮含量

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-29 DOI: 10.31603/pharmacy.v8i1.6582

Anita Puspa Widiyana, D. Illian

{"title":"PHYTOCHEMICAL ANALYSIS AND TOTAL FLAVONOID CONTENT ON ETHANOL AND ETHYL ACETATE EXTRACT FROM NEEM (AZADIRACHTA INDICA JUSS.) LEAVES UTILIZING UV–VIS SPECTROPHOTOMETRIC","authors":"Anita Puspa Widiyana, D. Illian","doi":"10.31603/pharmacy.v8i1.6582","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.6582","url":null,"abstract":"The plants are rich sources of secondary metabolites, a bioactive compound that has various activities. Flavonoids, as a type of secondary metabolite, have been reported to possess anticancer, antioxidant, antibacterial, anti-inflammatory, and antiviral activities. Flavonoid has been found abundantly in Neem (Azadirachta indica Juss.) leaves. The difference in total flavonoid content might be an occurrence of the different solvent types and concentrations. The present study was conducted to analyze the phytochemical and determine the total flavonoid content of neem leaves extract using two different solvents (namely 70% ethanol and ethyl acetate) using UV-Vis spectrophotometric. The extraction from neem leaves was performed by maceration method. Phytochemical analysis of neem leaves reveals several secondary metabolites: flavonoids, steroids/triterpenoids, tannins, and saponins. Total flavonoid content from both extracts was determined by utilizing the UV-Vis spectrophotometric method at a maximum wavelength of 428.2 nm with three repetitions, and also quercetin was used as a standard. Total flavonoid content from neem leaves extract in solvents of 70% ethanol and ethyl acetate had a value of 118.57 ± 0.08 mg/g QE and 74.17 ± 0.20 mg/g QE, respectively. Neem leaves extract in solvents of 70% ethanol and ethyl acetate had identical phytochemical content. Total flavonoid content of neem leaves from 70% ethanol extract was higher than ethyl acetate extract.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44473791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

ANALYSIS OF TOTAL FLAVANOID LEVELS OF FENNEL LEAVES (FOENICULUM VULGARE) ETHANOL EXTRACT BY SPECTROPHOTOMETRY VISIBEL 分光光度法测定茴香叶乙醇提取物中总黄酮含量

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-28 DOI: 10.31603/pharmacy.v8i1.4972

Novena Yety Lindawati, A. Ni'ma

引用次数: 1

APPLICATION D-OPTIMAL METHOD ON THE OPTIMIZATION OF FORMULATION OF KINTAMANI ARABICA COFFEE GEL (Coffea arabica L.) D-最优化方法在阿拉伯咖啡胶配方优化中的应用

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-28 DOI: 10.31603/pharmacy.v8i1.6115

H. Wijaya, I. P. R. K. P. Wiratama, Pande Ketut Pramita Desna Putri, Kadek Sutri Ariyanthini, Elisabeth Angelina, Nieke Andina, Putu Saradevi Naripradnya, E. I. Setyawan

{"title":"APPLICATION D-OPTIMAL METHOD ON THE OPTIMIZATION OF FORMULATION OF KINTAMANI ARABICA COFFEE GEL (Coffea arabica L.)","authors":"H. Wijaya, I. P. R. K. P. Wiratama, Pande Ketut Pramita Desna Putri, Kadek Sutri Ariyanthini, Elisabeth Angelina, Nieke Andina, Putu Saradevi Naripradnya, E. I. Setyawan","doi":"10.31603/pharmacy.v8i1.6115","DOIUrl":"https://doi.org/10.31603/pharmacy.v8i1.6115","url":null,"abstract":"Arabica coffee (Coffea arabica L.) kintamani is a superior agricultural product from Bali. Arabica coffee (Coffea arabica L.) contains many compounds, one of which is caffeine which is beneficial for health and beauty. This study aims to formulate kintamani arabica coffee beans into a gel dosage form. The optimization formula of kintamani arabica coffee bean gel was made using the D-Optimal method using a combination of HPMC and propylene glycol as observation variables and spreadability, pH, and viscosity of the gel preparation as experimental responses. The study of caffeine from the gel preparation was carried out using a Franz diffusion cell. Caffeine content in the gel preparation and its release are determined by spectrophotometric method. The results showed that the amount of HPMC used would increase the viscosity value (+14113.92) and decrease the spreadability (-0.29) and pH (-6.59167E-003) of the gel. The greater the amount of propylene glycol used will decrease the viscosity value (-2484.54) and increase the spreadability value (+0.30) and pH (+0.31802) of the gel. The conclusion of this study is the use of a combination of HPMC and propylene glycol (6%:17%) resulted in the optimum formula with a viscosity value of 44,070 cps, a spreadability value of 3.6 cm, and a pH value of 5.32. The caffeine content obtained in the gel preparation was 188.47 g and the amount of caffeine released from the gel preparation for 6 hours of testing was 4.95%.","PeriodicalId":17722,"journal":{"name":"Jurnal Farmasi Sains dan Praktis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49619534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

COST OF ILLNESS DIABETES MELITUS TIPE 2: NARRATIVE REVIEW 2型糖尿病的疾病成本:叙述性回顾

Jurnal Farmasi Sains dan Praktis Pub Date : 2022-04-28 DOI: 10.31603/pharmacy.v8i1.5958

Nadia Pramasari, D. Endarti, Anna Wahyuni Widayanti

引用次数: 0