Journal of Health Sciences and Medicine最新文献

{"title":"Colonoscopy indications and findings in older adults","authors":"O. Bakkaloğlu, T. Eşkazan, Selcuk Candan, Yusuf Erzi̇n, Ahmet Merih Dobrucali","doi":"10.32322/jhsm.1351555","DOIUrl":"https://doi.org/10.32322/jhsm.1351555","url":null,"abstract":"Aims: The share of older population is increasing globally. Colonoscopy is a frequently used diagnostic/therapeutic procedure, no study to our knowledge comprehensively examines the indications and findings of colonoscopy in geriatric population. We aimed to reveal these in older adults. Methods: Colonoscopy procedures performed in older adults (≥65 years), which covered a 5-year period (2017-2022), were analyzed retrospectively. Indications and findings of colonoscopies were assessed. The relationship between the indications and the associated findings was also evaluated on an indication basis. Results: In the study, 2370 colonoscopy procedures were examined. 27.8% were performed in very old (≥75 years) patients. Colonoscopy was completed in 84.3%. Colon cleansing was not optimal in approximately one-fourth. The frequency of completion of colonoscopies and optimal cleaning were similar in the very old. Iron deficiency anemia (IDA) or fecal occult blood test (FOBT) positivity and screening colonoscopy were the common indications. Regarding indications, IDA-FOBT positivity and bleeding were more frequent, screening colonoscopy, IBD and polyp control were less frequent in the very old group. Colonoscopy was reported as normal in 42.4% of the patients, while polyps (28.3%) and diverticula (17.5%) were the common findings. Among findings tumor, diverticula and solitary rectal ulcer were higher in the very old. IDA -FOBT positivity, bleeding, and colonoscopy performed due to findings of other imaging modalities were related to diagnosis of a tumor. Conclusion: In this study, we presented the indications and results of colonoscopy in a large number of older patients. The main indications for colonoscopy can be listed as IDA-FOBT positivity, screening colonoscopy and control of previous polyp-tumor. Near one of two colonoscopies were found to be normal, polyps and diverticula were the major pathologies in the rest. It should be emphasized that IDA -FOBT positivity, bleeding, and findings of other imaging modalities were related to tumor in colonoscopy.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-life data of azacitidine-venetoclax combination in acute myeloid leukemia patients: a single center experience","authors":"T. Bulduk, Melda Cömert, Ebru Kiliç, S. Sayın, Murat Yıldırım, M. Aylı","doi":"10.32322/jhsm.1359253","DOIUrl":"https://doi.org/10.32322/jhsm.1359253","url":null,"abstract":"Aims: To evaluate real-life data on the efficacy and safety of Venetoclax (Ven) therapy used in combination with hypomethylating agent (HMA) in patients with acute myeloid leukemia (AML). Methods: The records of newly diagnosed, relapsed or refractory (RR) AML patients over 18 years of age who were planned to be treated with Azacitidine (AZA) combined with Ven because they were not suitable for intensive chemotherapy and patients who received AZA combined with Ven maintenance therapy after achieving remission were retrospectively analyzed. The standard protocol for patients is subcutaneous or intravenous AZA 75 mg/m2 on days 1-7/ every 28 days + oral Ven treatment 100-400 mg/day for 28 days. The treatment response rates, survival times, and side effect profiles of 18 newly diagnosed patients, 12 RR patients, and 4 patients receiving AZA+Ven as maintenance treatment between January 2021 and March 2022 were evaluated. Results: It was found that 8 of the 34 patients (23.5%) who were examined in the present study died before the first response could be evaluated. When the response rates were evaluated, complete response (CR) or complete remission with incomplete blood count recovery (CRi) (CR+CRi) was found to be 61% in the group receiving AZA+Ven in the first line, and CR+CRi was 50% in the group receiving AZA+Ven because of RR AML. In the group receiving AZA+Ven in the first line, the average Overall Survival (OS) was 8.00 months (95% CI: 1.58-14.41), and 7.00 months in the RR group (95% CI: 1.78-12, 21). All patients in the group receiving AZA+Ven for maintenance purposes were alive and the median follow-up period was 12.50±6.02 months in this group (Mean±SD). The most common side effect was neutropenia, and the most common cause of death was disease progression. Conclusion: In AML patients ineligible for intensive treatment due to advanced age or comorbidities, real-life data of AZA+Ven therapy with effective CR+CRi rates and a manageable spectrum of side effects promise hope.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing the MRI findings to diagnose acute appendicitis in pregnant women","authors":"Zeynep Yildiz, Fuldem Mutlu","doi":"10.32322/jhsm.1362716","DOIUrl":"https://doi.org/10.32322/jhsm.1362716","url":null,"abstract":"Aims: To assess the performance of magnetic resonance ımaging (MRI ) scale for the diagnosis of acute appendicitis in pregnant women and to determine the added diagnostic value of MRI imaging. Methods: In this retrospective study, the data of patients who presented to our hospital emergency department between January 2018 and December 2021, had clinical and laboratory findings consistent with acute appendicitis, and were diagnosed with radiological imaging, were extracted from the hospital automation system and used for statistical analysis. Ultrasound (US) was used as the first-line diagnostic method for pregnant patients, and magnetic resonance imaging (MRI) was used as the second-line diagnostic method. The success of US and MRI examinations in diagnosing acute appendicitis was evaluated. In MRI examinations, the mean values of appendix diameter and wall thickness parameters were examined, and the sensitivity, specificity, positive predictive value, and negative predictive value of periappendiceal fat tissue intensity increase, T2A lumen hyperintensity, and periappendiceal fluid parameters were evaluated. Additionally, the frequency of acute appendicitis according to trimesters was examined. SPSS v20.0 (IBM SPSS Statistics for Windows, Version 20.0; Armonk, NY, USA) package program was used for the analysis. Results: When the medical records of 200 patients diagnosed with appandicitis were retrospectively examined, it was determined that there were 13 pregnant cases diagnosed with MRI during this period. Sensitivity, specificity, positive predictive value, and negative predictive value were evaluated for parameters including intraluminal T2A hyperintensity, wall thickness, periappendiceal fluid accumulation, and periappendiceal fatty tissue intensity increase. İntraluminal T2A hyperintensity and also periappendiceal fatty tissue intensity increase parameter sensitivity was 100%, however the wall thickness parameter had a sensitivity of 60% and the periappendiceal fluid accumulation parameter had a sensitivity of 80%. the periappendiceal fatty tissue intensity increase parameter had a a specificity of 33.3%, which is the lowest ratio among the other parameters. there was also no significant difference in the frequency of acute appendicitis according to trimesters Conclusion: MRI examination has a high success rate and can be used as the primary diagnostic method for pregnant appandicitis cases. In terms of parameter evaluation, the highest positive predictive value (90.9%) is found by the parameter of intraluminal T2 hyperintensity, and the parameter of periappendiceal fluid collection is found to be in the second place. The success of T2A lumen hyperintensity and periappendiceal fat tissue intensity increase parameters, especially in excluding negative cases, was found to be quite high.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"11 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The investigation of serum nectin-4 levels in patients with early onset preeclampsia","authors":"Zuat Acar, M. Obut, Zeynep GEDİK ÖZKÖSE, Sadun Sucu, Salim Sezer, Mevlüt Bucak, I. Dağ, Sezgi Güllü Erciyestepe, İsmail Özdemi̇r","doi":"10.32322/jhsm.1350858","DOIUrl":"https://doi.org/10.32322/jhsm.1350858","url":null,"abstract":"Aims: We aimed to investigate the level and predictive value of soluble nectin-4 in early onset preeclampsia (EOPE). Methods: Forty-three patients with EOPE and 41 healthy normotensive pregnant women participated in this prospective case-control study. The groups were matched for gestational age and gravidity. Serum nectin-4 levels were compared between groups. The ROC curve was drawn to show the predictive value of nectin-4 for EOPE. Patients were followed up until the end of labor, and perinatal outcomes were recorded. Results: The demographic characteristics of the two groups were similar. Serum nectin-4 level was significantly increased in EOPE cases compared to controls (226.46±119.6 ng/ml vs. 156.54±44.8 ng/ml, p=0.001). The ROC showed that at > 160.938, the sensitivity and specificity were 67.44% and 82.93%, respectively [AUC:0.822, (CI:0.724 - 0.897), and (p< 0.001)]. Significant inverse correlations were found between nectin-4 levels and poor obstetric outcomes. Conclusion: Maternal serum nectin-4 levels were significantly higher in patients with EOPE compared with controls. Increased nectin-4 levels may contribute to the development of EOPE through possible oxidative, immunological, and inflammatory mechanisms adversely affecting trophoblastic cells.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evaluation of tear production and dry eye symptoms in patients with osteoporosis","authors":"Esin BENLİ KÜÇÜK, Erkut Küçük","doi":"10.32322/jhsm.1362476","DOIUrl":"https://doi.org/10.32322/jhsm.1362476","url":null,"abstract":"Aims: Osteoporosis is a systemic skeletal disorder characterized by decreased bone mass, compromised bone density and strength. Dry eye is a common disease of the ocular surface characterized by tear film instability with ocular discomfort, pain, and visual disturbances. Both conditions share risk factors, including age, gender, and hormonal factors. In this study, our aim is to assess the tear production and dry eye symptoms in patients with osteoporosis and compare their results a control group without osteoporosis. Methods: In this cross-sectional study, we evaluated 32 osteoporosis patients and 30 age-matched controls without osteoporosis. Tear production was assessed using Schirmer test and the symptoms of dry eye using Ocular Surface Disease Index (OSDI) questionnaire. The results of both groups were compared. Results: The mean age of the osteoporosis group was 61.4±4.9 years, and the mean age of the control group was 57.7±6.4 years (p:0.224). The Schirmer test results were 12.3±7.4 mm for the osteoporosis group and 23.1±13.7 mm for the control group. The Schirmer test results were significantly lower in the osteoporosis group (p:0.009). The mean OSDI scores for the osteoporosis group was 30.4±23.1 while it was 20.6±14.6 for the control group. The difference was not statistically significant (p:0.329). Conclusion: This study reveals a potential connection between osteoporosis and dry eye. Patients with osteoporosis have lower tear production compared to control group without osteoporosis. Further research is necessary to understand this relationship and its implications.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring occupational safety and health in future workscapes","authors":"Cengiz Akyildiz","doi":"10.32322/jhsm.1355643","DOIUrl":"https://doi.org/10.32322/jhsm.1355643","url":null,"abstract":"Aims: The aim of this manuscript is to address the evolving dynamics of work, which are placing increasing demands on current occupational safety and health (OSH) protocols. It emphasizes the need for a more adaptable approach to ensure safe and efficient work environments. The primary objective is to introduce new frameworks capable of handling the uncertainties of the future in OSH. Methods: To tackle the challenges posed by the changing landscape of work, the U.S. National Institute for Occupational Safety and Health (NIOSH) has adopted a strategic foresight approach. This approach is rooted in future studies and strategic planning, allowing NIOSH to anticipate future challenges in OSH. It involves creating well-structured and informed scenarios of potential futures, enabling organizations to prepare effectively for upcoming challenges and capitalize on emerging opportunities. Results: This manuscript represents NIOSH's inaugural foray into strategic foresight. The results showcase the integration of strategic foresight methods to enhance institutional readiness in the realm of OSH. The study delves deep into the anticipated trajectories of OSH research and protocols, offering valuable insights into the future of OSH. Conclusion: In conclusion, the evolving nature of work necessitates a more adaptable approach to occupational safety and health. NIOSH's strategic foresight venture marks a significant step towards achieving this goal. By proactively preparing for future challenges and opportunities, organizations can ensure safer and more efficient work environments. This manuscript provides a foundation for enhancing institutional readiness and navigating the evolving landscape of OSH research and protocols.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric forearm fractures: evaluating implant removal timing and complications with exposed titanium-elastic nail tips","authors":"Fatih Gölgelioğlu, Mustafa Yalın","doi":"10.32322/jhsm.1354354","DOIUrl":"https://doi.org/10.32322/jhsm.1354354","url":null,"abstract":"Aims: The current study investigates complication rates, timing of implant removal, and correlations between removal timing and complications/refractures in pediatric forearm fracture patients who had exposed titanium-elastic nail (TEN) tips. Methods: This retrospective single-center study analyzed pediatric forearm fractures in patients who underwent TEN with exposed tips. Inclusion criteria covered cases between August 2018 and January 2022, focusing on children with both-bone forearm fractures and unsuccessful conservative treatment. Data included demographics, fracture details, reduction type, implant removal timing, complications, and refracture rates. Results: Between August 2018 and August 2022, the study involved 65 children (54 boys, 11 girls), aged 4 to 15 years. Implant removal occurred at 4 to 11 weeks, on average at 7.17±1.52 weeks. Fracture location was distal 1/3 (9.2%), middle 1/3 (78.5%), proximal 1/3 (12.3%). The predominant causes of fractures were falls (89.2%). Fracture types consisted of open fractures (6.2%) and closed fractures (93.8%). Reduction methods included mini-open reduction (9.2%) and closed reduction (90.8%). Implant removal occurred at or before 6 weeks for 43.1% of cases, while it exceeded 6 weeks for 56.9% of cases. Complications were noted in 21.5% of cases, encompassing delayed union (14.3%), hypertrophic granuloma (7.1%), infection (21.4%), skin irritation (42.9%), and refracture (14.3%). Clinical outcomes were classified as excellent in 83.1% of cases and good in 16.9% of cases. No statistically significant differences were observed in complications (p=0.351) or clinical outcomes (p=0.441) based on implant removal timing. Conclusion: Contrary to belief, exposing nail tips, not burying them, is safe, cost-effective, and leads to minimal complications with positive clinical outcomes. Implant removal timing did not significantly impact clinical outcomes or complications. TENs used in forearm fractures can be removed before 6 weeks when adequate union is observed.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropometric analysis of Turkish fetuses’ face","authors":"Işik Tuncer","doi":"10.32322/jhsm.1313544","DOIUrl":"https://doi.org/10.32322/jhsm.1313544","url":null,"abstract":"Aims: This study aims at collecting data on the morphology of the face during its development in order to get detailed information on the neighboring structures and its variations using anatomical dissections and obtain normal morphometric values of the face growth and human fetuses during the 1st, 2nd and 3rd trimester. Methods: This study was performed on spontaneously aborted 97 fetuses (49 males, 48 females) (11 first trimester, 63 second trimester and 24 third trimester) that have no observable congenital malformations or maternal history of risky pregnancy. The fetuses were taken from a Gynecology Department of a School of Medicine and a Maternity Hospital in Konya. Thirteen direct facial anthropometric measurements were performed on 97 volunteers. The data obtained were compared with the data of previous studies. Results: Means and standard deviations of the parameters in regard to gestational weeks and trimesters were calculated. A significant correlation was observed between all parameters and gestational age (p","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reappraisal of the role of Helicobacter pylori in chronic spontaneous urticaria","authors":"Sinem ÖRNEK ÖZDEMİR, Emek Özgür","doi":"10.32322/jhsm.1352876","DOIUrl":"https://doi.org/10.32322/jhsm.1352876","url":null,"abstract":"Aims: Chronic spontaneous urticaria (CSU) is one of the most prevalent skin disorders. Helicobacter pylori (HP) infection has been linked to CSU, and HP eradication therapy has been questioned as a viable treatment option. However, studies have produced contradictory results. In addition, recent studies suggest that gastritis, rather than HP bacteria, may be responsible for CSU symptoms. Herein, we aimed to ascertain the prevalence of HP infection in CSU, explore associations between HP infection, gastritis, and CSU severity or treatment response in CSU, and investigate the impact of HP eradication therapy on the CSU course. Methods: We retrospectively analyzed CSU patients who were investigated for HP infection. Patient characteristics, in-clinic urticaria activity scores (ic-UAS) and urticaria control test (UCT) scores, and CSU treatment responses were compared across different patient groups. Results: The study included 325 CSU patients, of whom 57.2% were HP-positive and 60.9% had gastritis. The mean baseline ic-UAS showed no difference between HP-positive and HP-negative patients (2.55±2 vs 2.45±1.98, p>0.05) or between patients with and without gastritis (2.33±2 vs 2.51±2, p>0.05). HP-positive patients had higher rates of elevated CRP levels (45% vs 29.9%, p=0.023) and ASST positivity (54.8% vs 29.8%, p0.05). Conclusion: Over half of CSU patients have been found to be infected with HP. However, the HP bacterium itself, the eradication of HP, or gastritis have no significant effect on CSU severity or treatment response.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of color stability of bulk-fill restorative materials with different properties","authors":"Özge Çeliksöz, H. Tepe, Batucan Yaman","doi":"10.32322/jhsm.1347899","DOIUrl":"https://doi.org/10.32322/jhsm.1347899","url":null,"abstract":"Aims: The present study aims to evaluate the color stability of bulk-fill restorative materials with different properties over different time periods when immersed in a coffee solution. Methods: According to the selected restorative materials, the study groups were formed as follows: CNT/light (Alkasite, Cention N, Ivoclar Vivadent, light cure mode), CNT/self (Alkasite, Cention N, self cure mode) EQF (Glass hybrid restorative, Equia Forte HT, GC Corporation), AU (Single-shade bulk fill, Aura Bulk Fill, SDI), Z550 (Filtek Z550, 3M) (control group). A total of 50 samples (n=10) were prepared using standard molds (2mmx10mm). After finishing and polishing procedures, all samples were kept in distilled water at 37°C for 24 hours. The first color measurement (L*a*b ) was performed with Vita Easy Shade V (VITA Zahnfabrik). Samples were added to the coffee solution. Color was measured at times simulating 7 days, 1 month, 6 months and 1 year of clinical service. Color changes (ΔE1, ΔE2, ΔE3 and ΔE4) were calculated according to the CIE L*a*b system. Normality of the data was examined by D'Agostino & Pearson omnibus normality test. One-way ANOVA analysis and Tukey test were performed. Statistical significance level was set at p 0.05 and statistical analysis software (GraphPad Prism 6.0, GraphPad Software, USA) was used for the analysis. Results: According to ΔE1 results; clinically unacceptable color change (ΔE>3.3) values were observed in CNT/light and CNT/self groups. The color change values of EQF, Z550 and AU groups were statistically similar (p>0.05). According to ΔE2 results; an unacceptable color change (ΔE>3.3) was observed in all groups except EQF. According to ΔE3 results; an unacceptable color change (ΔE>3.3) was observed in all groups. According to ΔE4 results; an unacceptable color change (ΔE>3.3) was observed in all groups. The color change values of EQF, Z550 and AU groups were statistically similar (p>0.05). CNT/light group showed the highest color change in all time periods, followed by CNT/self group. Conclusion: The color stability of single-shade bulk fill material and glass hybrid restorative materials is similar to the control group. The color stability of alkasite material needs to be improved.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}