Journal of Health Sciences and Medicine最新文献

{"title":"A biomarker predicting unfavorable prognosis in malignant pleural mesothelioma: systemic immune–inflammation index","authors":"Hüsnü Baykal, Filiz Çimen","doi":"10.32322/jhsm.1242687","DOIUrl":"https://doi.org/10.32322/jhsm.1242687","url":null,"abstract":"Aim: Malignant pleural mesothelioma (MPM) is an extremely mortal condition. Only a few prognostic biomarkers have been described for MPM. Our study looked into the association between patient survival and the Systemic Immune Inflammation Index (SII). \u0000Material and Method: A total of 158 patients who were admitted to our hospital between January 2013 and December 2022, and had a histopathologically confirmed diagnosis of MPM were included in the study. Before treatment, hematological parameters and SII were determined. A Spearman's correlation analysis was performed to analyze the correlation of mean survival with hematological parameters. \u0000Results: The study involved 158 patients in all. 70 patients had a history of smoking, the median age was 63 years, the mean survival time was 15.3 months, and 57.6% of the participants were men. The epithelioid type (84.2%) was the most prevalent histological subtype, and 29 patients had stage 4 illnesses. Of the participants, 84% had received chemotherapy, and 22% had received radiotherapy before. Among the 39 patients who had surgery, 5 had an extrapleural pneumonectomy. SII mean±sd was (1427.2±1207.3). The patients with stage 4 disease had significantly shorter survival (p=0.001). The patients who had surgery survived significantly longer (p=0.01). Hemoglobin (Hb) (r:0.21, p:0.01) and Hematocrit (Hct) (r:0.18, p:0.03) values showed weak positive correlations with mean survival. It was evident that mean survival got shorter as SII (r:-0.17, p:0.04) and neutrophil-lymphocyte ratio (NLR) (r:-0.19, p:0.02) values got higher. On the other hand, there was a strong positive association between mean survival and the lymphocyte-monocyte ratio (LMR) (r:0.21, p:0.01). When the parameters that had statistically significant differences among the groups were taken as control variables and the statistical analysis was re-performed, it was found that Hgb and Hct values as well as NLR and LMR ratios lost their significant correlations with survival. However, the SII ratio was still negatively correlated with survival (r:-0.16, p:0.04). \u0000Conclusion: Pretreatment SII is a noninvasive and easy-to-calculate biomarker that predicts the prognosis of MPM. It is negatively correlated with mean survival regardless of the tumor stage and surgical management.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133840111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the effect of age-related hearing loss on visual memory","authors":"Mahmut Huntürk Atilla","doi":"10.32322/jhsm.1244208","DOIUrl":"https://doi.org/10.32322/jhsm.1244208","url":null,"abstract":"Aim: To investigate the effect of age-related hearing loss on visual memory. \u0000Material and Method: 20 participants with normal hearing loss and 38 participants with hearing loss were included in the study. All of the patients were older than 65 years. Pure tone audiometry, speech audiometry and Benton visual retention test were applied to all participants. \u0000Results: Mean Benton test score of the hearing-normal and the hearing loss group were 13.10±1.48 and 8.81±3.27 respectively. Patients were divided into three groups as hearing-normal, hearing loss with WRS greater than 80% and hearing loss with WRS lower than 80%. In terms of Benton scores there was statistically significant difference between groups (p","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124783095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of anterior midline incision and double incision in the surgical treatment of tibial plateau fractures","authors":"Ö. Bozduman","doi":"10.32322/jhsm.1218765","DOIUrl":"https://doi.org/10.32322/jhsm.1218765","url":null,"abstract":"Aim: Tibial plateau fractures are complex fractures that often develop after high-energy trauma, often involving intra-articular fractures. They are rarely treated conservatively. Surgical planning and approach are very important in preventing possible complications. In this study, we compared two different incisions in the same fracture types. \u0000Material and Method: A total of 26 patients (20 males-6 females) with tibial plateau fractures were included in the study. Twelve of the patients were selected from those using anterior midline incisions, and 14 from those using double incisions as anterolateral and posteromedial incisions. The mean age of the patients is 50.8 (24-76) years. The distribution of patients according to fracture classification was 9 Schatzker type-6, 17 Schatzker type-5. Average follow-up time is 34.1 months (24.5-42.2). Postoperative complications, union time, joint range of motion, radiological Rasmussen criteria, Medial Proximal Tibial Angle (MPTA) and Posterior Proximal Tibial Angle (PPTA) measurements, Lachman and valgus-varus stress tests for ligament stability evaluation, Hospital for Special Surgery (HSS) and visual analogue scale (VAS) assessments were performed to evaluate the clinical status of the patients. Results were compared between both incision groups. \u0000Results: Union in the anterior midline was 11.07 (±1.68) weeks and bilateral union was 9.96 (±1.35) weeks (p :0.074). Rasmussen scoring was 14.83 (±2.16) in the anterior group and 14.57 (±2.13) in the bilateral group (p:0.760). The MPTA was 85.35 (±3.97) degrees in the anterior group, and the MPTA was 86.40 (±3.74) degrees in the bilateral group (p: 0.492). PPTA was 80.77 (±1.95) degree in the anterior group, and PPTA was 80.85 (±1.78) degree in the bilateral group. HSS score was 70 (±9.02) in the anterior group and HSS score was 71.71 (±1.15) in the bilateral group (p:0.681). Rom was measured as 101.67 (±12.67) degrees in the anterior group and 107.86 (±13.54) degrees in the bilateral group (p: 0.243). The VAS anterior group was 2.83 (±1.64) and the VAS bilateral group was 3.36 (±2.09) (p:0.491).Instability was seen in 1 patient in the anterior group and 1 patient in the bilateral group (p:1). Infection was observed in 1 patient in the anterior group and in 3 patients in the bilateral group (p:0.598). \u0000Conclusion: The anterior incision is as effective a surgical approach as bilateral incision in correct patient preferences. Surgical site visibility in anterior incision is satisfactory. The principal aspect is to perform the correct surgical planning for the correct patient.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129405659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of second- and third-trimester complete uterine rupture cases followed up in a tertiary hospital: a retrospective cohort study","authors":"Ç. Özgökçe, Aydın Ocal, O. Demirci","doi":"10.32322/jhsm.1227049","DOIUrl":"https://doi.org/10.32322/jhsm.1227049","url":null,"abstract":"Aim: There are not many studies that compared the uterine rupture cases pertaining to different trimesters of pregnancy in terms of the changes in relevant risk factors and fetomaternal outcomes. In this context, this study was carried out to comparatively analyze the cases who were diagnosed with complete uterine rupture and gave birth in the hospital where this study was conducted in terms of the relevant risk factors and fetomaternal outcomes. \u0000Material and Method: The population of this retrospective study consisted of patients who were diagnosed with complete uterine rupture and gave birth in our hospital between January 2015 and June 2022. Patients’ demographic characteristics, cesarean section, labor induction histories, and fetal and maternal outcomes were recorded. The patients included in this study were divided into two groups based on the trimester when the complete uterine rupture occurred as second- and third-trimester complete uterine rupture groups. The groups were compared in terms of fetal, maternal, and obstetric outcomes. \u0000Results: Out of the 56718 deliveries performed during the study period, a total of 27 complete uterine rupture cases, of whom 10 had second-, and 17 had third-trimester uterine rupture, were included in the study sample. Accordingly, the incidence of rupture was calculated as 0.047%. Of these 27 cases, 9 had re-pregnancy. Bilateral hypogastric artery ligation was performed in seven patients and six of these patients were in the third trimester rupture group. Of the 27 cases with complete uterine rupture, 19 had a cesarean section history. All 8 cases that did not have a cesarean section history had a complete uterine rupture in the third trimester. \u0000Conclusion: Complete uterine rupture is associated with adverse maternal and fetal outcomes. Fertility-sparing surgery (primary repair) is the first-line therapy. The prognosis of second-trimester uterine ruptures is more unfavorable compared to third-trimester uterine ruptures from the fetal point of view yet more favorable from the maternal point of view.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128567739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between uric acid variability and cardiovascular risk factors in patients with diabetes","authors":"E. Akbaş, Nergis Akbaş","doi":"10.32322/jhsm.1226971","DOIUrl":"https://doi.org/10.32322/jhsm.1226971","url":null,"abstract":"Aim: This study aimed to evaluate the relationship between uric acid variability and cardiovascular risk factors, primarily albuminuria and blood lipids, in patients with diabetes. \u0000Material and Method: Data from 174 patients with diabetes whose biochemical parameters were examined at least once a year were collected over the course of five years of regular follow-up. The five-year averages and standard deviations of each parameter for each person were calculated. The adjusted standard deviation for each parameter was considered as a measure of individual variability. The patients were divided into two groups according to the median of the mean uric acid and the median of the adjusted standard deviation of uric acid. \u0000Results: Between low and high uric acid variability groups, while there was no statistically significant difference for the mean values of following parameters, there was a difference in the variability of glucose (p=0.010), HbA1c (p=0.016), total cholesterol (p=0.008), and low-density lipoprotein-cholesterol (p=0.002). Moreover, there was difference in mean albuminuria (p= 0.019), albuminuria variability (p=0.040), mean triglyceride (p=0.011), triglyceride variability (p=0.018), and mean high-density lipoprotein-cholesterol cholesterol (p=0.008). \u0000Conclusion: Clinicians should pay attention to uric acid variability in addition to basal uric acid levels since it is associated with albuminuria, an atherogenic lipid profile, renal functions, and the variability of these parameters, independent of HbA1c and glucose levels.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121092697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The late-term results in our patients operated for lumbar spine fractures","authors":"E. Izci, Oğuzhan Pekince, F. Keskin","doi":"10.32322/jhsm.1250055","DOIUrl":"https://doi.org/10.32322/jhsm.1250055","url":null,"abstract":"Aim: The current study aimed to evaluate the late-term results of patients operated for lumbar spine fractures in our clinic. \u0000Material and Method: 134 patients from January 2012 to January 2020 were treated with “short-segment pedicle instrumentation” for lumbar fractures in our neurosurgery department. Patients with a burst fracture of a single lumbar vertebra were included. The final sample consisted of 67 patients who were followed up over the years with radiographs before and after surgery and CT scans at the final follow-up. \u0000Results: The results showed that 60% of the patients were rated as Denis P1, 35% as P2, and 5% as P3. Screw breakage was observed in seven patients, and 67 patients underwent revision surgery. Furthermore, the fractured vertebral body’s height was improved at the final follow-up stage, and an increase was witnessed from the preoperative figure of 16.4 mm to 25.8 at the final follow-up. At the final follow-up, the average Cobb angle was -11.6° preoperatively, and 6.3° after the operation and the correction loss was 12.1° which was severe in the middle part of the vertebra. By the final follow-up, disc spaces were narrowed below and above the fractured vertebra, and no correlation was found between clinical outcomes and adjacent disc degeneration. \u0000Conclusion: We concluded that short-segment pedicle instrumentation produced satisfactory long-term results for lumbar fractures. To achieve adequate outcomes, correct management of complications and evaluation of various factors must be focused on.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122149923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does YouTube™ give us accurate information about bruxism?","authors":"H. Bilir, H. Yilanci","doi":"10.32322/jhsm.1229704","DOIUrl":"https://doi.org/10.32322/jhsm.1229704","url":null,"abstract":"Aim: The aim of this study is to evaluate the quality of the information provided by the most watched videos about bruxism on YouTube™. \u0000Material and Method: The results of YouTube™search were examined using the keyword “bruxism”. The searching limited to the first 130 videos. DISCERN and the video information and quality index (VIQI) and the criteria were used for evaluating the videos. Also, the interaction index and the viewing rate of the videos were calculated. The Kruskal-Wallis H Test, Pearson's Chi-Square Test, Spearman's rho correlation were used for statistical analyses. Significance level was taken as p","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124554175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlations of renal parenchymal attenuations and CT severity scores on three consecutive CTs in COVID-19 patients","authors":"A. Kaya, Burcu Akman","doi":"10.32322/jhsm.1227526","DOIUrl":"https://doi.org/10.32322/jhsm.1227526","url":null,"abstract":"Aim: We aimed to investigate the correlation between the temporal changes of computed tomography severity score (CT-SS) ​​and mean renal parenchymal attenuation (MRPA) values in consecutive chest computed topographies (CT). \u0000Material and Method: This retrospective, single-center study included 65 (≥18 years) COVID-19 patients with positive RT-PCR tests. A radiologist calculated three consecutive chest CT-SSs and measured the MPRAs on CTs from the upper half of each kidney included in the cross-section. Paired samples test and Wilcoxon signed-rank test were used to evaluate the temporal changes of mean renal parenchymal attenuation (RPA) and median CT-SS values, in three consecutive CTs. Spearman's test was used to evaluate the correlation of each RPA and CT-SS value on three consecutive CTs. \u0000Results: The study population included 65 patients with a mean age of 61.49±13.91 years. A total of 36/65 (55.4%) were male. We found a significant increase between the first and second CT-SS (p","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125488902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemorrhage","authors":"Idris Kocatürk, Sedat Gülten","doi":"10.32322/jhsm.1225428","DOIUrl":"https://doi.org/10.32322/jhsm.1225428","url":null,"abstract":"Aim: This study aims to evaluate immature granulocyte count (IG#) and percentage (IG%) in the prediction of mortality in spontaneous intracerebral hemorrhage (SICH). \u0000Material and Method: Demographic characteristics and laboratory test results of patients diagnosed with SICH and admitted to the neurology clinic in a tertiary hospital between January 1, 2020, and January 1, 2022, were recorded. One hundred ten patients were included in the study. While 80 of these patients constituted the group that recovered after treatment, 30 of them formed the group that died despite treatment. IG and other laboratory and clinic parameters were statistically compared in both groups. \u0000Results: Of 110 patients, 45 (42.7%) were female, and 65 (57.3%) were male. IG counts were higher in the non-survival group than in the survival group (p=0.001). When the patients were divided according to low IG% (=0.6), 30 patients were in the high IG# group, and 80 patients were in the low IG% group. White blood cell (WBC), neutrophil count (NEUT#), monocyte count (MONO#), IG#, neutrophil-lymphocyte ratio (NLR), and hemorrhage volume (HV) values were statistically significantly higher in the high IG% group than in the low IG% group; Glasgow coma score (GCS) and percentage of lymphocytes (LYMPH%) values were significantly lower too. In addition, the mortality rate in the high IG# group was significantly higher than the mortality rate in the low IG% group (53.23% vs. 17.5%). \u0000Conclusion: IG is a new, easily accessible, inexpensive, and promising marker for predicting in-hospital mortality in patients with SICH.","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132613099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative assessment of patients' admission to urology departments during and before the COVID-19 pandemic: a retrospective cohort study","authors":"A. Keleş, A. Karakeçi, T. Ozan, E. Yuvanç","doi":"10.32322/jhsm.1220104","DOIUrl":"https://doi.org/10.32322/jhsm.1220104","url":null,"abstract":"Aim: To determine the diseases that presented to the urology department during the COVID-19 pandemic and for hospital-based comparison with the diseases that presented in the same period of the previous year. \u0000Material and Method: In this retrospective follow-up study, patients who were admitted to the tertiary university hospital and secondary state hospital urology departments between April-July 2019 and April-July 2020 were included in the study. We searched the health administrative data using the International Classification of Diseases-10 codes. The number and variety of patients who were admitted to the urology departments in the same months of 2019 and 2020 were compared. \u0000Results: In both hospitals, the total number of admissions decreased during the pandemic in 2020 compared to the pre-pandemic year. Also, elective admissions decreased in 2020 compared to the pre-pandemic year (p","PeriodicalId":176872,"journal":{"name":"Journal of Health Sciences and Medicine","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130607298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}