Journal Pharmasci (Journal of Pharmacy and Science)最新文献_第3页

Effect of Plant Growth Regulators on Callus Induction in Piper betle L. var. Nigra 植物生长调节剂对黑椒愈伤组织诱导的影响

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2023-01-22 DOI: 10.53342/pharmasci.v8i1.302

Junairiah Junairiah, Ni’matuzahroh Ni’matuzahroh, Nabilah Istighfari Zuraidassanaaz, L. Sulistyorini

{"title":"Effect of Plant Growth Regulators on Callus Induction in Piper betle L. var. Nigra","authors":"Junairiah Junairiah, Ni’matuzahroh Ni’matuzahroh, Nabilah Istighfari Zuraidassanaaz, L. Sulistyorini","doi":"10.53342/pharmasci.v8i1.302","DOIUrl":"https://doi.org/10.53342/pharmasci.v8i1.302","url":null,"abstract":"Callus culture is one of the plant tissue culture techniques that used to study aspects of plant nutrition, somatic embryogenesis, cell suspension culture, secondary metabolite production, and genetic transformation. Callus induction was carried by adding growth regulators. Black betel (Piper betle L. var. nigra) is a medicinal plant that has the potential to produce secondary metabolites. The aim of this study was to obtain the best formula for callus induction of P. betle L. var. nigra. The single growth regulator used is 2,4-Dichlorophenoxyacetic acid (2,4-D), Benzyl Amino Purine (BAP), Indole Butyric Acid (IBA), Indole Acetic Acid (IAA), and Naphthalene Acetic Acid (NAA) with variations the concentration used is 0; 0.5; 1; 1.5; 2; 2.5 mg/L. Each treatment consisted of 6 replicates grown using Murashige and Skoog (MS) medium in vitro for eight weeks. The results showed that the 1.5 mg/L 2,4-D treatment produced the highest fresh weight (1389.5 mg) and dry weight (55.7 mg). Callus P. betle L. var. Nigra in various treatments showed various textures such as compact and friable with callus colors such as white, greenish-white, brownish-white, yellowish-green, greenish-yellow, brownish-yellow, greenish-brown, brown, and gray.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"125 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78457061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antifungal Activity of Auricularia nigricans Methanol Extract against Candida parapsilosis using The Well Method 黑木耳甲醇提取物对假丝酵母菌的孔法抑菌活性研究

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2023-01-22 DOI: 10.53342/pharmasci.v8i1.300

Septiani Resika Dewi, Floreta Fiska Yuliarni

引用次数: 0

Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent 不同溶剂洋葱皮提取物次生代谢产物的鉴定

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-03 DOI: 10.53342/pharmasci.v7i2.289

Mercyska Suryandari, G. G. Kusumo

{"title":"Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent","authors":"Mercyska Suryandari, G. G. Kusumo","doi":"10.53342/pharmasci.v7i2.289","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.289","url":null,"abstract":"Onion peels (Allium cepa L.) is often disposed of without being used and ends up as waste in markets that can pollute the environment. Onion peels can potentially be developed for treatment as an anti-cancer because of its phytochemical compounds. Previous studies have shown that secondary metabolites found in onion peels using different solvents produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolite compounds from onion peels extract (Allium cepa L.) qualitatively when extracted using 5 different solvents. This research was conducted using a phytochemical screening method on the onion peels extract (Allium cepa L.). n-Hexane, Ethyl Acetate, Acetone, Ethanol 96%, and Chloroform were used in the maceration extraction method separately. The results showed that the yield value was 0.96%; 2.66%; 3.90%; 4.80%; 1.62%. The results showed that acetone, ethanol, and chloroform extracts of onion peels extract (Allium cepa L.) contained alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins. Meanwhile, the ethyl acetate extract of onion peels contains alkaloids, flavonoids, steroids, terpenoids, and tannins. Lastly, the n-hexane extract of the onion peels only contains steroids and terpenoids. So it can be concluded that secondary metabolites in onion peels extract contain alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86420929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical Screening of Chloroform Extract from Javanese Long Pepper which Dried Through 2 Different Methods 2种不同干燥方法爪哇长椒氯仿提取物的植物化学筛选

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-03 DOI: 10.53342/pharmasci.v7i2.292

Diah Wulan Safitri, Meyke Herina Syafitri

{"title":"Phytochemical Screening of Chloroform Extract from Javanese Long Pepper which Dried Through 2 Different Methods","authors":"Diah Wulan Safitri, Meyke Herina Syafitri","doi":"10.53342/pharmasci.v7i2.292","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.292","url":null,"abstract":"Fruit is easily damaged and has a short shelf life due to the high water content. Drying is one of the post-harvest handling processes that can reduce the water content of the product to increase stability during product distribution and storage. Javanese long pepper (Piper retrofractum Vahl.) is included in the 10 largest raw materials absorbed by the traditional medicine industry. Purpose of this study is to carry out phytochemical screening of chloroform extract from javanese long pepper which dried through 2 different methods. Group 1 was air-dried, while group II was pre-treated with blanching, which was boiled for a few minutes before drying in direct sunlight. The dried implicia produced from both groups were macerated with chloroform for 3 days each. The maceration filtrate then tested to determine the secondary metabolite compounds contained in it through phytochemical screening. The test is carried out by observing the presence or absence of a precipitate formed or the color change that occurs after the addition of reagents. The results showed that both groups were positive for alkaloids, flavonoids and steroids, but negative for terpenoids, tannins, and saponins. There was no difference in content between the two treatment groups.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"10 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85302237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prescribing Profile among Pregnancy in the Outpatient Pharmacy Installation of Bokor Hospital, Malang 玛琅Bokor医院门诊药房设置孕妇处方概况

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-02 DOI: 10.53342/pharmasci.v7i2.291

Endang Susilowati, Dini Mei Arisa

{"title":"Prescribing Profile among Pregnancy in the Outpatient Pharmacy Installation of Bokor Hospital, Malang","authors":"Endang Susilowati, Dini Mei Arisa","doi":"10.53342/pharmasci.v7i2.291","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.291","url":null,"abstract":"Drug therapy in pregnant women is important because it can cross the placental blood barrier so that it has a negative effect on fetal development. This study aims to determine the profile of drug prescription in pregnant women including drug therapy class, drug name, drug category based on fetal safety. This study aims to determine the profile of drug prescribing in pregnant women including drug therapy class, type of drug and drug category based on safety for the fetus. The study used retrospective data in the form of 100 prescription sheets at the Outpatient Pharmacy Installation of Bokor Hospital, Malang Regency, the period July-September 2021. The results showed that there were 14 different classes of drug therapy prescribed to pregnant women. The number of vitamin and mineral prescription cases was 116 prescriptions (54%) with 100 prescriptions (46%) consisting of 13 drug therapy classes. Five percentages of prescriptions were vitamin-mineral 54%, analgesic 18.5%, tocolytic 5.1%. 4.6% and antiemetics 4.2%. Four types of drugs were prescribed from each therapeutic class, namely mefenamic acid (analgesic), Isoxsuprine HCl (tocolytic), Ondansetron (antiemetic) and amoxicillin (antibiotic). Based on drugs to the fetus, drugs prescribed to pregnant women are included in categories A, B, C and D. In conclusion, the most prescriptions for pregnant women are vitamin and mineral supplements, analgesics, and tocolytic drugs.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"50 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89407741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organoleptic and Qualitative Test of Borax Content in Meatballs and Cilok in Lakasantri Surabaya 泗水拉卡桑里肉丸和香菇中硼砂含量的感官和定性检验

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-01 DOI: 10.53342/pharmasci.v7i2.288

Dewi Yuliani Setianingsih, Cicik Herlina Yulianti

{"title":"Organoleptic and Qualitative Test of Borax Content in Meatballs and Cilok in Lakasantri Surabaya","authors":"Dewi Yuliani Setianingsih, Cicik Herlina Yulianti","doi":"10.53342/pharmasci.v7i2.288","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.288","url":null,"abstract":"Meatballs and cilok are favorite’s food in public. Based on market surveys, it turns out that there are still foods containing dangerous preservatives like borax. Borax is a toxic material and can poison cells if ingested in large quantities. The purpose of this study was to determine the organoleptic characteristics of meatballs and cilok stored for 3 days at room temperature. In addition, to determine the presence or absence of borax in meatballs and cilok, a qualitative test was carried out using a borax rapid test kit. This research method was carried out by organoleptic and qualitative testing of meatball and cilok samples obtained around SMPN 28 Lakasantri, Surabaya. Sampling was done by total sampling method. Based on the number of meatball and cilok traders around SMPN 28 Lakasantri Surabaya, there were 5 meatball traders and 5 cilok traders with a total of 10 samples. Then, organoleptic and qualitative tests were carried out using a borax rapid test kit. The results showed that the meatball and cilok samples obtained around SMPN 28 Lakasantri Surabaya after being stored for three days at room temperature, experienced a decrease in quality in the form of a softer texture, a duller color and some even started to grow mold and mildew, and a rotting smell. Meanwhile, based on a qualitative test on all samples of meatballs and cilok using a borax rapid test kit, the results were negative.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"208 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90475346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Curcuma (Curcuma xanthorrhiza Roxb.) Extract Capsule Treatment on Mice Blood Glucose Level 姜黄(Curcuma xanthorrhiza Roxb.)提取物胶囊对小鼠血糖水平的影响

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-01 DOI: 10.53342/pharmasci.v7i2.280

Diah Nurcahyani

引用次数: 0

Decrease in Calcium Oxalate Levels in Porang Bulbs With Variations in Contact Time, Temperature and Volume of Averrhoa bilimbi Juice Solution 草酸钙含量随接触时间、温度和体积的变化而降低

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-01 DOI: 10.53342/pharmasci.v7i2.285

R. Wardani

引用次数: 0

Effect of Gamma Radiation and Curcuma xanthorrhiza Extract Capsules on Damage Mus musculus Liver Cells 伽玛辐射和姜黄提取物胶囊对损伤小鼠肝细胞的影响

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-01 DOI: 10.53342/pharmasci.v7i2.281

Septiana Kurniasari, F. K. Hentihu

{"title":"Effect of Gamma Radiation and Curcuma xanthorrhiza Extract Capsules on Damage Mus musculus Liver Cells","authors":"Septiana Kurniasari, F. K. Hentihu","doi":"10.53342/pharmasci.v7i2.281","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.281","url":null,"abstract":"Gamma radiation produces free radicals when interacting with cells. The free radical can be neutralized and caught by an antioxidant compound. This research aimed to analyze the effect of gamma radiation exposure and treated Curcuma xanthorrhiza extract capsules on the cells damage to the mice’s liver. This study used mice of the Balb/c strain with an average body weight of 18-20 grams, aged 6-8 weeks and male. This study required 80 animals for 3 groups, namely K- (without radiation and extract), R- (gamma radiation without extract of Curcuma xanthorrhiza) and R+ (given extract and then irradiated). Radiation exposure was given for 10 minutes, 20 minutes, 30 minutes, 40 minutes and 50 minutes, while Curcuma xanthorrhiza extract was given in 5 different doses, namely, 1.4 g/kg body weight; 2.0 g/kg body weight; 2.6 g/kg body weight; 3.2 g/kg body weight and 3.8 g/kg body weight. The damaging of liver cells is done by analyzing its microscopic picture. The result showed increased exposure time to gamma radiation causes increased cell damage. Cell damage is low in a row of increasing Curcuma xanthorrhiza extract dose. The adequate amount of Curcuma xanthorrhiza extract is 3.8 g/kg body weight.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78044618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Assay Of Cyperus rotundus Rhizomes Against Gram Positive And Gram Negative Bacteria 香附根茎对革兰氏阳性菌和革兰氏阴性菌的抑菌试验

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2022-08-01 DOI: 10.53342/pharmasci.v7i2.294

Diana Yuni Anjarsari, K. Lestari

{"title":"Antibacterial Assay Of Cyperus rotundus Rhizomes Against Gram Positive And Gram Negative Bacteria","authors":"Diana Yuni Anjarsari, K. Lestari","doi":"10.53342/pharmasci.v7i2.294","DOIUrl":"https://doi.org/10.53342/pharmasci.v7i2.294","url":null,"abstract":"Studies on antibacterial tests derived from natural ingredients were more intensively carried out. This was to reduce the side effects of using antibiotics related to the incidence of pathogenic bacteria. Nut grass tubers were one of the natural ingredients that are widely known for their benefits for human health. Nut grass tubers were also known to contain antibacterial compounds such as flavonoids, tannins, saponins and so on. This study aims to determine the potential of nut grass tuber extract as antibacterial of Gram positive and Gram negative. This study used a completely randomized design with the treatment of teki grass tuber extract with concentrations of 25%, 50% and 100%. Based on the research, it was known that the nut grass tubers were able to inhibit the growth of Gram positive and Gram negative bacteria in the category of weak to moderate ability. This study used the treatment of teki grass tuber extract with concentrations of 25%, 50% and 100%. Based on the research, it was found that the tuber of teki grass was able to inhibit the growth of Gram positive bacteria with the highest inhibition at 100% concentration of 5.53 mm and Gram negative with the highest inhibition at 100% concentration of 6.57 mm.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81954497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0