Journal of veterinary emergency and critical care最新文献

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Letter to the Editor: Improving the effectiveness of CPR in all breeds of dogs 致编辑的信:提高CPR在所有犬种中的有效性。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-11-06 DOI: 10.1111/vec.13346
Eric Marc Rottenberg
{"title":"Letter to the Editor: Improving the effectiveness of CPR in all breeds of dogs","authors":"Eric Marc Rottenberg","doi":"10.1111/vec.13346","DOIUrl":"10.1111/vec.13346","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"724-725"},"PeriodicalIF":1.3,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The authors respond 作者做出了回应。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-11-03 DOI: 10.1111/vec.13347
Sabrina N. Hoehne, Claudia Iannucci, Vishal D. Murthy, Guillaume Dutil, Arianna Maiolini
{"title":"The authors respond","authors":"Sabrina N. Hoehne, Claudia Iannucci, Vishal D. Murthy, Guillaume Dutil, Arianna Maiolini","doi":"10.1111/vec.13347","DOIUrl":"10.1111/vec.13347","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"726-727"},"PeriodicalIF":1.3,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71435013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective evaluation of the clinical course and outcome of zinc toxicosis due to metallic foreign bodies in dogs (2005–2021): 55 cases 犬金属异物锌中毒的临床过程和结果的回顾性评价(2005-2021):55例。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-10-17 DOI: 10.1111/vec.13330
Cameron S. Henke DVM, Matthew W. Beal DVM, DACVECC, Rebecca A. L. Walton DVM, DACVECC, Joanna B. Finstad DVM, Brooke K. Newmans DVM, Michael P. Sliman DVM, Molly A. Racette DVM, DACVECC, Nyssa A. Levy MS, DVM, DACVECC
{"title":"Retrospective evaluation of the clinical course and outcome of zinc toxicosis due to metallic foreign bodies in dogs (2005–2021): 55 cases","authors":"Cameron S. Henke DVM,&nbsp;Matthew W. Beal DVM, DACVECC,&nbsp;Rebecca A. L. Walton DVM, DACVECC,&nbsp;Joanna B. Finstad DVM,&nbsp;Brooke K. Newmans DVM,&nbsp;Michael P. Sliman DVM,&nbsp;Molly A. Racette DVM, DACVECC,&nbsp;Nyssa A. Levy MS, DVM, DACVECC","doi":"10.1111/vec.13330","DOIUrl":"10.1111/vec.13330","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the overall clinical course of zinc toxicosis in dogs including source, time to source control, incidence of hemolytic anemia, acute liver injury (ALI), acute kidney injury (AKI), and pancreatitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective case series from 2005 to 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Six university veterinary teaching hospitals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Fifty-five client-owned dogs with known zinc toxicosis due to metallic foreign body (MFB) ingestion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>The most common source of zinc was US pennies minted after 1982 (67.3%). Forty-five of 55 (81.8%) dogs survived and 10 of 55 (18.2%) died or were euthanized. Median length of hospitalization for survivors and nonsurvivors was 3 days. The most common clinical sequelae of zinc toxicosis were anemia (87%), ALI (82%), coagulopathy (71%), thrombocytopenia (30.5%), AKI (26.9%), and acute pancreatitis (5.5%). Most dogs (67.3%) required blood products and 83% of dogs achieved a stable HCT or PCV in a median of 24 hours after MFB removal. The median duration of illness prior to presentation was 48 hours for both survivors and nonsurvivors and there was no impact of time to presentation on the incidence of ALI, AKI, or pancreatitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Zinc toxicosis secondary to MFB ingestion should be considered a differential diagnosis for dogs with gastrointestinal signs, hemolytic anemia, ALI, hemostatic abnormalities, AKI, and pancreatitis. AKI may be a more common sequela of zinc toxicosis than previously suspected. Acute pancreatitis is a rare but potentially serious sequela to zinc toxicosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"676-684"},"PeriodicalIF":1.3,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The successful use of a subcutaneous catheter in the management of severe subcutaneous emphysema in a dog with laryngeal crush injury and tracheostomy tube placement 成功使用皮下导管治疗犬喉挤压伤和气管造口管置入后的严重皮下气肿。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-10-04 DOI: 10.1111/vec.13322
Maude Poirier DVM, DACVECC, Rebecca A. L. Walton DVM, DACVECC
{"title":"The successful use of a subcutaneous catheter in the management of severe subcutaneous emphysema in a dog with laryngeal crush injury and tracheostomy tube placement","authors":"Maude Poirier DVM, DACVECC,&nbsp;Rebecca A. L. Walton DVM, DACVECC","doi":"10.1111/vec.13322","DOIUrl":"10.1111/vec.13322","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the placement of a subcutaneous catheter in a dog for the management of severe subcutaneous emphysema secondary to severe laryngeal crushing injury and temporary tracheostomy tube placement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>A 6-year-old male neutered Kelpie suffered a severe laryngeal crushing injury following a dog attack. Case management included the placement of a temporary tracheostomy tube due to severe respiratory compromise and inspiratory dyspnea associated with the crush injury. During hospitalization, the patient developed severe subcutaneous emphysema, pneumomediastinum, and a pneumothorax as a complication of the laryngeal crushing injury and temporary tracheostomy. A subcutaneous catheter was placed to manage the recurrent subcutaneous emphysema while the tracheostomy stoma healed. Five months posttrauma, the dog returned to normal with mild stridor during excitement and while panting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>This is the first report in veterinary medicine describing the use of a subcutaneous catheter for the management of subcutaneous emphysema secondary to laryngeal crush injury and temporary tracheostomy tube placement.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"710-714"},"PeriodicalIF":1.3,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstracts from the International Veterinary Emergency and Critical Care Symposium, the European Veterinary Emergency and Critical Care Annual Congress, and the ACVECC VetCOT Veterinary Trauma & Critical Care Conference 2023 国际兽医紧急情况和重症监护研讨会、欧洲兽医紧急情况与重症监护年会和ACVECC兽医创伤与重症监护会议2023摘要
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-09-20 DOI: 10.1111/vec.13338
{"title":"Abstracts from the International Veterinary Emergency and Critical Care Symposium, the European Veterinary Emergency and Critical Care Annual Congress, and the ACVECC VetCOT Veterinary Trauma & Critical Care Conference 2023","authors":"","doi":"10.1111/vec.13338","DOIUrl":"https://doi.org/10.1111/vec.13338","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 S1","pages":"S1"},"PeriodicalIF":1.3,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13338","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50139429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstracts from the International Veterinary Emergency and Critical Care Symposium, the European Veterinary Emergency and Critical Care Annual Congress, and the ACVECC VetCOT Veterinary Trauma & Critical Care Conference 2023 国际兽医紧急情况和重症监护研讨会、欧洲兽医紧急情况与重症监护年会和2023年ACVECC兽医创伤与重症监护会议摘要。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-09-20 DOI: 10.1111/vec.13336
{"title":"Abstracts from the International Veterinary Emergency and Critical Care Symposium, the European Veterinary Emergency and Critical Care Annual Congress, and the ACVECC VetCOT Veterinary Trauma & Critical Care Conference 2023","authors":"","doi":"10.1111/vec.13336","DOIUrl":"10.1111/vec.13336","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 S1","pages":"S2-S42"},"PeriodicalIF":1.3,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41148116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Issue Information - Prelim 问题信息-Prelim
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-09-20 DOI: 10.1111/vec.13215
{"title":"Issue Information - Prelim","authors":"","doi":"10.1111/vec.13215","DOIUrl":"https://doi.org/10.1111/vec.13215","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 5","pages":"488-491"},"PeriodicalIF":1.3,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13215","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50152896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of equine and food animal emergency caseload by time of day, day of week, time of year, holiday, and phase of moon at an academic ambulatory and referral hospital 在学术流动医院和转诊医院按时间、星期、一年中的时间、假日和月相分配的马和食用动物急诊病例。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-09-14 DOI: 10.1111/vec.13334
Meggan T. Graves DVM, Xiaojuan Zhu PhD
{"title":"Distribution of equine and food animal emergency caseload by time of day, day of week, time of year, holiday, and phase of moon at an academic ambulatory and referral hospital","authors":"Meggan T. Graves DVM,&nbsp;Xiaojuan Zhu PhD","doi":"10.1111/vec.13334","DOIUrl":"10.1111/vec.13334","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Determine the association of time of day, day of week, time of year, holiday, and phase of moon on academic ambulatory and hospital emergency caseload for equine and food animal species.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Large animal teaching hospital emergency service.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Equine and food animals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>None.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>The hospital database was searched for after-hours on-farm and in-hospital emergencies seen from 2014 to 2020. Variables included date and time of admission, species (equine or food/fiber animal [FA]), and hospital service (field or in-hospital). The association of the caseload with time of day, day of week, day of year (holiday, full moon, or new moon), and season of year was defined and examined. The majority of equine field-based emergencies occurred on the weekend, in contrast to 44.8% of hospital cases. Most equine emergencies occurred between 4:00 p.m. and midnight on weekdays and between 8:00 a.m. and 4:00 p.m. on weekends for both field (89.1% and 46.9%) and hospital (82.8% and 48%) services. The same was true for FA cases on the farm (90% and 49.2%) and in the hospital (85% and 51.4%). More equine cases (67%) were seen in the field than FA. Winter had the fewest emergency cases for all species and locations, and spring had the most for FA. The majority of holiday equine emergencies were seen in the field (62.2%), but the majority of holiday FA emergencies were seen in the hospital (66.3%). Moon phase had no significance on caseload for all species and locations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Saturdays and Sundays were the busiest days for all species and services. Winter was the slowest time for emergencies for all species and services. Most emergencies were seen between 4:00 p.m. and midnight on weekdays and between 8:00 a.m. and 4:00 p.m. on Sundays and Saturdays.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"696-704"},"PeriodicalIF":1.3,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10240250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective evaluation of acute kidney injury in horses treated with nonnitrogenous bisphosphonates (2013–2020): 8 cases 2013-2020年非含氮双膦酸盐治疗马急性肾损伤8例回顾性分析
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-09-11 DOI: 10.1111/vec.13324
Lisa Edwards DVM, DACVIM, DACVECC, K. Gary Magdesian DVM, DACVIM, DACVECC, DACVCP
{"title":"Retrospective evaluation of acute kidney injury in horses treated with nonnitrogenous bisphosphonates (2013–2020): 8 cases","authors":"Lisa Edwards DVM, DACVIM, DACVECC,&nbsp;K. Gary Magdesian DVM, DACVIM, DACVECC, DACVCP","doi":"10.1111/vec.13324","DOIUrl":"10.1111/vec.13324","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe a population of horses with acute kidney injury (AKI) following administration of bisphosphonates including clinical signs, clinicopathologic data, treatment, and outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective study from August 2013 to July 2020.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Veterinary university teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Eight adult horses with AKI following administration of nonnitrogenous bisphosphonates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>None.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Five horses received intramuscular clodronate (5/8; 62.5%) and 3 horses received intravenous tiludronate (3/8; 37.5%). Six horses (6/8; 75%) received concurrent nonsteroidal anti-inflammatory drugs. The most common initial presenting complaint was poor appetite (6/8; 75%), followed by abnormal urination (2/8; 25%). At the time of initial evaluation, the mean serum or plasma creatinine was 451.72 ± 190.06 μmol/L (5.11 ± 2.15 mg/dL) and BUN was 18.84 ± 8.85 mmol/L (52.75 ± 24.77 mg/dL). Five horses (5/6; 83.3%) had either an increased number of red blood cells (<i>n</i> = 4) or hemoprotein (<i>n</i> = 1) in the urine. All horses were treated with IV isotonic, balanced crystalloids either as a bolus, continuous rate infusion, or a combination of the 2. Seven horses (7/8; 87.5%) survived the initial episode of AKI and 1 horse (1/8; 12.5%) was euthanized. Of the 7 surviving horses, 2 horses (2/7; 28.5%) went on to develop chronic renal dysfunction. Warmblood breeds were overrepresented in the AKI group (<i>P</i> = 0.008; odds ratio: 11.5, 95% confidence interval: 1.8–72.1), when compared to horses that received bisphosphonates during the study period and did not develop AKI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Bisphosphonate administration, with or without concurrent nonsteroidal anti-inflammatory drugs, can be associated with AKI in horses. Serum creatinine should be monitored prior to and following bisphosphonate treatment to minimize this risk. Further evaluation of renal function is warranted in horses that develop clinical signs of poor appetite, lethargy, or altered urination in the days following bisphosphonate treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"685-695"},"PeriodicalIF":1.3,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10202857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of platelet additive solution for prolonging storage of functional canine platelet concentrate 血小板添加液对功能性犬血小板浓缩物延长贮存期的评价。
IF 1.3 3区 农林科学
Journal of veterinary emergency and critical care Pub Date : 2023-08-28 DOI: 10.1111/vec.13335
Avin Arjoonsingh DVM, Jillian M. Haines DVM, MS, DACVIM, Julianne K. Hwang PhD, Sarah C. Guess DVM, MS, DACVIM, K. Jane Wardrop DVM, MS, DACVP
{"title":"Evaluation of platelet additive solution for prolonging storage of functional canine platelet concentrate","authors":"Avin Arjoonsingh DVM,&nbsp;Jillian M. Haines DVM, MS, DACVIM,&nbsp;Julianne K. Hwang PhD,&nbsp;Sarah C. Guess DVM, MS, DACVIM,&nbsp;K. Jane Wardrop DVM, MS, DACVP","doi":"10.1111/vec.13335","DOIUrl":"10.1111/vec.13335","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To assess storage lesion development, platelet function, and bacterial growth in canine platelet concentrates (PCs) stored in a platelet additive solution (PAS) or a plasma control at 4°C for 21 days.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Design&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Prospective, ex vivo, experimental controlled study.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Setting&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;University veterinary teaching hospital.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Animals&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Ten units of canine PCs collected from blood bank donations.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Interventions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The PCs were separated into 2 bags, 1 containing 100% plasma and the other containing 35% plasma and 65% of a PAS (Plasma-Lyte A), and stored at 4°C for 21 days. At days 0, 7, 14, and 21, PCs were analyzed for the presence of swirling, aggregate formation, platelet counts, platelet indices, glucose, lactate, lactate dehydrogenase, Pv&lt;span&gt;co&lt;/span&gt;&lt;sub&gt;2&lt;/sub&gt;, Pv&lt;span&gt;o&lt;/span&gt;&lt;sub&gt;2&lt;/sub&gt;, aggregation via light aggregometry, activation percentages using flow cytometry, and bacterial growth.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Measurements and main results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Cold-stored PCs in both PAS and plasma control maintained mean pH &gt;6.8 and mean lactate &lt;9.0 mmol/L over 21 days, with no difference in glucose utilization. Swirl was maintained in both solutions for most days (76/80 combined total samples), with no difference in aggregate formation between solutions. The Pv&lt;span&gt;co&lt;/span&gt;&lt;sub&gt;2&lt;/sub&gt; was higher in plasma on all days (&lt;i&gt;P&lt;/i&gt; &lt; 0.001), with no difference in Pv&lt;span&gt;o&lt;/span&gt;&lt;sub&gt;2&lt;/sub&gt;. Platelet indices did not reflect significant storage lesion development in either solution. Lactate dehydrogenase did not differ between solutions but did increase from day 7 to day 21. Mean maximal aggregation percentage was reduced overall but with no significant difference between solutions. The only observed difference in mean activation percentage between solutions was in PAS on day 7, which was significantly higher than plasma (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). No bacterial growth occurred during storage.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Cold storage in PAS and plasma allowed PCs to be stored for up to 21 days with minimal storage lesion development, maintenance of plat","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"33 6","pages":"656-664"},"PeriodicalIF":1.3,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13335","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10440247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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