发布求助
文献互助 智能选刊 最新文献

Journal of Virus Eradication最新文献

筛选
英文 中文
Title Page 标题页
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100294
{"title":"Title Page","authors":"","doi":"10.1016/j.jve.2022.100294","DOIUrl":"https://doi.org/10.1016/j.jve.2022.100294","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100294"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022002321/pdfft?md5=905e381c7a1919cef5bd4ab98c64f889&pid=1-s2.0-S2055664022002321-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138201408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP 1.12 – 00076 The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11 赖氨酸甲基转移酶SMYD5扩增HIV-1转录，并在转录后被Tat和USP11上调
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100117
D. Boehm , V. Lam , M. Schnolzer , M. Ott
{"title":"PP 1.12 – 00076 The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11","authors":"D. Boehm , V. Lam , M. Schnolzer , M. Ott","doi":"10.1016/j.jve.2022.100117","DOIUrl":"https://doi.org/10.1016/j.jve.2022.100117","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100117"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022000553/pdfft?md5=5c66675a337b9a30223228861147ea30&pid=1-s2.0-S2055664022000553-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138201252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substantial uneven proliferation of CD4+ T cells during recovery from acute HIV infection is sufficient to explain the observed expanded clones in the HIV reservoir 在急性HIV感染的恢复过程中，CD4+ T细胞的大量不均匀增殖足以解释在HIV库中观察到的扩增克隆
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100091
Florencia A. Tettamanti Boshier , Daniel B. Reeves , Elizabeth R. Duke , David A. Swan , Martin Prlic , E. Fabian Cardozo-Ojeda , Joshua T. Schiffer
{"title":"Substantial uneven proliferation of CD4+ T cells during recovery from acute HIV infection is sufficient to explain the observed expanded clones in the HIV reservoir","authors":"Florencia A. Tettamanti Boshier ,&nbsp;Daniel B. Reeves ,&nbsp;Elizabeth R. Duke ,&nbsp;David A. Swan ,&nbsp;Martin Prlic ,&nbsp;E. Fabian Cardozo-Ojeda ,&nbsp;Joshua T. Schiffer","doi":"10.1016/j.jve.2022.100091","DOIUrl":"10.1016/j.jve.2022.100091","url":null,"abstract":"<div><p>The HIV reservoir is a population of 1–10 million anatomically dispersed, latently infected memory CD4<sup>+</sup> T cells in which HIV DNA is quiescently integrated into human chromosomal DNA. When antiretroviral therapy (ART) is stopped and HIV replication initiates in one of these cells, systemic viral spread resumes, rekindling progression to AIDS. Therefore, HIV latency prevents cure. The detection of many populations of identical HIV sequences at unique integration sites implicates CD4<sup>+</sup> T cell proliferation as the critical driver of reservoir sustainment after a prolonged period of effective ART. Initial reservoir formation occurs during the first week of primary infection usually before ART is started. While empirical data indicates that both <em>de novo</em> infection and cellular proliferation generate latently infected cells during early untreated infection, it is not known which of these mechanisms is predominant. We developed a mathematical model that recapitulates the profound depletion and brisk recovery of CD4<sup>+</sup> T cells, reservoir creation, and viral load trajectory during primary HIV infection. We extended the model to stochastically simulate individual HIV reservoir clones. This model predicts the first detection of HIV infected clones approximately 5 weeks after infection as has recently been shown <em>in vivo</em> and suggests that substantial, uneven proliferation among clones during the recovery from CD4<sup>+</sup> lymphopenia is the most plausible explanation for the observed clonal reservoir distribution during the first year of infection.</p></div>","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 4","pages":"Article 100091"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/b7/main.PMC9792356.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial JVE 8.4 编辑JVE 8.4。
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100311
{"title":"Editorial JVE 8.4","authors":"","doi":"10.1016/j.jve.2022.100311","DOIUrl":"10.1016/j.jve.2022.100311","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 4","pages":"Article 100311"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/31/main.PMC9791823.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10449928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OP 3.5 – 00152 HIV-1RNA+infected CD4 T cell burden in acute HIV-1 infection and association with inflammatory markers OP 3.5–00152急性HIV-1感染中HIV-1RNA+感染的CD4 T细胞负荷及其与炎症标志物的关系
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100177
D. Bolton , M. Creegan , N. Jian , B. Slike , A. Tokarev , J. Ananworanich , S. Vasan , D. Hsu , N. Phanuphak , N. Chomont , S. Krebs
{"title":"OP 3.5 – 00152 HIV-1RNA+infected CD4 T cell burden in acute HIV-1 infection and association with inflammatory markers","authors":"D. Bolton ,&nbsp;M. Creegan ,&nbsp;N. Jian ,&nbsp;B. Slike ,&nbsp;A. Tokarev ,&nbsp;J. Ananworanich ,&nbsp;S. Vasan ,&nbsp;D. Hsu ,&nbsp;N. Phanuphak ,&nbsp;N. Chomont ,&nbsp;S. Krebs","doi":"10.1016/j.jve.2022.100177","DOIUrl":"10.1016/j.jve.2022.100177","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100177"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022001157/pdfft?md5=63b3f13cdeffb4f2917d948b455ad6da&pid=1-s2.0-S2055664022001157-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42520749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PP 7.7 – 00055 Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to a Dolutegravir-based antiretroviral regiment PP 7.7–00055转为基于多卢特格拉韦的抗逆转录病毒疗法后，循环复制能力强的潜伏HIV感染的静息CD4+T细胞暂时增加
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100269
R. Ferreira, S. Reynolds, A. Capoferri, S.N. Gowanlock, O. Baker, J. Miller, E. Brown, S. Saraf, C. Kirby, B. Lynch, J. Hackman, J. Lai, S. Tomusange, T. Kityamuweesi, S. Jamiru, A. Anok, P. Buule, D. Bruno, C. Martens, R. Rose, S. Lamers, R. Galiwango, A. Poon, T. Quinn, J. Prodger, A. Redd
{"title":"PP 7.7 – 00055 Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to a Dolutegravir-based antiretroviral regiment","authors":"R. Ferreira, S. Reynolds, A. Capoferri, S.N. Gowanlock, O. Baker, J. Miller, E. Brown, S. Saraf, C. Kirby, B. Lynch, J. Hackman, J. Lai, S. Tomusange, T. Kityamuweesi, S. Jamiru, A. Anok, P. Buule, D. Bruno, C. Martens, R. Rose, S. Lamers, R. Galiwango, A. Poon, T. Quinn, J. Prodger, A. Redd","doi":"10.1016/j.jve.2022.100269","DOIUrl":"https://doi.org/10.1016/j.jve.2022.100269","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43765716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP 1.40 – 00074 Blood Brain Barrier Pericytes and the Molecular Impact of Active and Latent HIV Infection PP 1.40–00074血脑屏障外周细胞与活动和潜伏HIV感染的分子影响
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100144
O. Naranjo , S. Torices , P. Clifford , M. Stevenson , M. Toborek
{"title":"PP 1.40 – 00074 Blood Brain Barrier Pericytes and the Molecular Impact of Active and Latent HIV Infection","authors":"O. Naranjo ,&nbsp;S. Torices ,&nbsp;P. Clifford ,&nbsp;M. Stevenson ,&nbsp;M. Toborek","doi":"10.1016/j.jve.2022.100144","DOIUrl":"10.1016/j.jve.2022.100144","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100144"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022000826/pdfft?md5=0a1fba96a71c7ab3a3eb5a63c9953f5b&pid=1-s2.0-S2055664022000826-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43972511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OP 3.4 – 00197 Infected naïve CD4+ T cells in children with HIV can proliferate and persist on ART 感染naïve CD4+ T细胞的儿童HIV病毒可以增殖和持续抗逆转录病毒治疗
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100176
M. Katusiime , S. Guo , V. Neer , S. Patro , X. Wu , A. Horner , A. Chahroudi , M. Mavigner , M. Kearney
{"title":"OP 3.4 – 00197 Infected naïve CD4+ T cells in children with HIV can proliferate and persist on ART","authors":"M. Katusiime ,&nbsp;S. Guo ,&nbsp;V. Neer ,&nbsp;S. Patro ,&nbsp;X. Wu ,&nbsp;A. Horner ,&nbsp;A. Chahroudi ,&nbsp;M. Mavigner ,&nbsp;M. Kearney","doi":"10.1016/j.jve.2022.100176","DOIUrl":"10.1016/j.jve.2022.100176","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100176"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022001145/pdfft?md5=1576dfa1a81bdfa1adf20c0fb4c668cf&pid=1-s2.0-S2055664022001145-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48900642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PP 3.1 – 00058 Development of a digital PCR assay to profile HIV expression at single-infected-cell resolution 在单感染细胞分辨率上建立一种数字PCR检测HIV表达的方法
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100181
F. Dragoni, M. Moskovljevic, F. Wu, A. Camilo-Contreras, F.R. Simonetti
{"title":"PP 3.1 – 00058 Development of a digital PCR assay to profile HIV expression at single-infected-cell resolution","authors":"F. Dragoni,&nbsp;M. Moskovljevic,&nbsp;F. Wu,&nbsp;A. Camilo-Contreras,&nbsp;F.R. Simonetti","doi":"10.1016/j.jve.2022.100181","DOIUrl":"10.1016/j.jve.2022.100181","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"8 ","pages":"Article 100181"},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2055664022001194/pdfft?md5=93b8314cb23541b78fd84d0c7bf932a7&pid=1-s2.0-S2055664022001194-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43255396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP 4.23 – 00148 Inhibition of the GSK3 pathway enhances CD8+ T cell stemness and functional capacities without promoting non-cytolytic suppression of HIV transcription PP 4.23–00148 GSK3途径的抑制增强CD8+T细胞的干性和功能能力，而不促进HIV转录的非细胞溶解性抑制
IF 5.5 4区 医学
Journal of Virus Eradication Pub Date : 2022-12-01 DOI: 10.1016/j.jve.2022.100231
M. Statzu, H. Wang, M. Paiardini, G. Silvestri, D. Kulpa
{"title":"PP 4.23 – 00148 Inhibition of the GSK3 pathway enhances CD8+ T cell stemness and functional capacities without promoting non-cytolytic suppression of HIV transcription","authors":"M. Statzu, H. Wang, M. Paiardini, G. Silvestri, D. Kulpa","doi":"10.1016/j.jve.2022.100231","DOIUrl":"https://doi.org/10.1016/j.jve.2022.100231","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46337498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信