Parm Khakh, Arshdeep S Marwaha, Ryaan El-Andari, Michelle M Graham, Evan J Wiens
{"title":"Prophylactic anticoagulation following anterior ST-elevation myocardial infarction for prevention of left ventricular thrombus: a narrative review.","authors":"Parm Khakh, Arshdeep S Marwaha, Ryaan El-Andari, Michelle M Graham, Evan J Wiens","doi":"10.1007/s11239-026-03271-x","DOIUrl":"https://doi.org/10.1007/s11239-026-03271-x","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ameer Awashra, Anwar Zahran, Mohammed AbuBaha, Abubakar Nazir, Mohammed Tareq Mutar, Ahmed Emara, Lubna Alnatour, Mohamed S Elgendy, Abdalhakim Shubietah, Mohammed Ruzieh, Fadi Safi
{"title":"Pulmonary embolism mortality in the United States: a nationwide analysis.","authors":"Ameer Awashra, Anwar Zahran, Mohammed AbuBaha, Abubakar Nazir, Mohammed Tareq Mutar, Ahmed Emara, Lubna Alnatour, Mohamed S Elgendy, Abdalhakim Shubietah, Mohammed Ruzieh, Fadi Safi","doi":"10.1007/s11239-026-03266-8","DOIUrl":"https://doi.org/10.1007/s11239-026-03266-8","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Establishment and validation of a machine learning-based prediction model for sepsis-induced coagulopathy.","authors":"Shilei Li, Fang Chen, Yuxin Dong, Haixia Chai, Yuanyuan Liu, Lei Xia, Heng Jin, Songtao Shou","doi":"10.1007/s11239-026-03272-w","DOIUrl":"https://doi.org/10.1007/s11239-026-03272-w","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yousef Radwan Alnomani, Mansour Algazar, Mohamed Mosad Omar, Mohamed A Aldemerdash, Kerollos Henes, Amr Arafa, Bushra Muneer Rageh, Ahmed Abdelaziz
{"title":"Angio-Seal plug-based versus dual ProGlide for transfemoral hemostasis in transcatheter aortic valve replacement: a systematic review and meta-analysis.","authors":"Yousef Radwan Alnomani, Mansour Algazar, Mohamed Mosad Omar, Mohamed A Aldemerdash, Kerollos Henes, Amr Arafa, Bushra Muneer Rageh, Ahmed Abdelaziz","doi":"10.1007/s11239-026-03261-z","DOIUrl":"https://doi.org/10.1007/s11239-026-03261-z","url":null,"abstract":"<p><p>Transcatheter aortic valve replacement (TAVR) carries risks of vascular and bleeding complications. We aimed to study the effectiveness of Angio-Seal combined with Perclose ProGlide versus dual Perclose ProGlide following transfemoral TAVR. We searched PubMed, Cochrane Library, Scopus, and WOS from inception until November 2024 for studies comparing Parclose ProGlide with Angio-Seal versus dual Parclose ProGlide in transfemoral TAVR. The primary outcome was major vascular complications, while other secondary outcomes were bleeding complications, the need for additional vascular closure device (VCD), minor vascular complications, unplanned surgical intervention, mortality, hematoma, pseudoaneurysm, and dissection. Dichotomous outcomes were pooled and analyzed using odds ratio (OR) with 95% confidence interval (CI) via the DerSimonian-Laird random-effect model. Seven studies (two RCTs and five observational studies) comprising 1,766 patients were included. In RCT-only analyses, single Perclose ProGlide combined with Angio-Seal showed no significant difference compared with dual Perclose ProGlide in major vascular complications (OR = 0.54, 95% CI [0.28-1.04], P = 0.07) or major/life-threatening bleeding (OR = 0.66, 95% CI [0.25-1.74], P = 0.40). However, it significantly reduced the need for additional vascular closure devices (OR = 0.11, 95% CI [0.05-0.24], P < 0.01) and minor vascular complications (OR = 0.52, 95% CI [0.38-0.72], P < 0.01). For dual Perclose ProGlide combined with Angio-Seal, no RCTs were available; observational evidence suggested a reduction in major/life-threatening bleeding compared to dual Perclose ProGlide (OR = 0.43, 95% CI [0.21 to0.92], p = 0.03), while there was no significant difference between the two groups upon excluding Costa et al. (EuroIntervention, 17:728-735, 2021) (OR = 0.56, 95% CI [0.26 to 1.21], p = 0.14). Based on the available RCTs, the combination of single Perclose ProGlide with Angio-Seal during transfemoral TAVR significantly reduces the need for additional vascular closure devices. It may also reduce minor vascular complications, but this effect is not consistently robust. The pooled analysis of observational studies suggests a potential benefit of dual Perclose ProGlide combined with Angio-Seal for major/life-threatening bleeding. However, this finding was not robust in sensitivity analyses and no RCTs have evaluated this strategy.</p>","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bleeding events in Asian patients with cancer-associated thrombosis: a 10-year single-centre experience.","authors":"Helma Azmar, Nor Rafeah Tumian, Yew Sheng Qian","doi":"10.1007/s11239-026-03270-y","DOIUrl":"https://doi.org/10.1007/s11239-026-03270-y","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insights on management of recurrence of Cancer-associated isolated distal deep vein thrombosis.","authors":"Wei Jia, Hehe Cui, Xuemin Zhang","doi":"10.1007/s11239-026-03254-y","DOIUrl":"https://doi.org/10.1007/s11239-026-03254-y","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147530207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriele Prandin, Giovanni Furlanis, Laura Mancinelli, Emanuele Vincis, Magda Quagliotto, Edoardo Ricci, Michele Malesani, Gianpiero Farina, Luigi Cattaruzza, Paola Caruso, Marcello Naccarato, Maja Ukmar, Paolo Manganotti
{"title":"Atrial fibrillation detected after ischemic stroke (AFDAS) diagnosed by short-term monitoring: the importance of frontal hypoperfusion.","authors":"Gabriele Prandin, Giovanni Furlanis, Laura Mancinelli, Emanuele Vincis, Magda Quagliotto, Edoardo Ricci, Michele Malesani, Gianpiero Farina, Luigi Cattaruzza, Paola Caruso, Marcello Naccarato, Maja Ukmar, Paolo Manganotti","doi":"10.1007/s11239-026-03267-7","DOIUrl":"https://doi.org/10.1007/s11239-026-03267-7","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia M Umińska, Michał Skrzypek, Klaudyna Grzelakowska, Piotr Adamski, Robert Gajda, Tomasz Białoszyński, Tomasz Dominiak, Bartosz Hudzik, Marek Gierlotka, Miłosz Jaguszewski, Ewa Laskowska, Piotr Niezgoda, Przemysław Trzeciak, Łukasz Szarpak, Paul A Gurbel, Young-Hoon Jeong, Zuzana Motovska, Udaya Tantry, Eliano Pio Navarese, Mariusz Gąsior
{"title":"Clinical outcomes and missed benefits related to clopidogrel overuse in acute coronary syndrome.","authors":"Julia M Umińska, Michał Skrzypek, Klaudyna Grzelakowska, Piotr Adamski, Robert Gajda, Tomasz Białoszyński, Tomasz Dominiak, Bartosz Hudzik, Marek Gierlotka, Miłosz Jaguszewski, Ewa Laskowska, Piotr Niezgoda, Przemysław Trzeciak, Łukasz Szarpak, Paul A Gurbel, Young-Hoon Jeong, Zuzana Motovska, Udaya Tantry, Eliano Pio Navarese, Mariusz Gąsior","doi":"10.1007/s11239-026-03256-w","DOIUrl":"https://doi.org/10.1007/s11239-026-03256-w","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Shaheer Bin Faheem, Own E Mohammad Najmi, Usman Ahmad, Mahad Ahmad, Ammar Yahya, Sanhia Maheshwari, Ashish Ashok Lal
{"title":"A Growing mortality divide: demographic and regional disparities in thromboembolism with hypertension, U.S. 1999-2023.","authors":"Muhammad Shaheer Bin Faheem, Own E Mohammad Najmi, Usman Ahmad, Mahad Ahmad, Ammar Yahya, Sanhia Maheshwari, Ashish Ashok Lal","doi":"10.1007/s11239-026-03260-0","DOIUrl":"https://doi.org/10.1007/s11239-026-03260-0","url":null,"abstract":"","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niklas Brodin, Peter Nymberg, Beata Borgström Bolmsjö, Peter J Svensson, Johan Elf, Bengt Zöller, Susanna Calling
{"title":"Metabolic syndrome and venous thromboembolism: the role of abdominal obesity and sex differences.","authors":"Niklas Brodin, Peter Nymberg, Beata Borgström Bolmsjö, Peter J Svensson, Johan Elf, Bengt Zöller, Susanna Calling","doi":"10.1007/s11239-026-03255-x","DOIUrl":"https://doi.org/10.1007/s11239-026-03255-x","url":null,"abstract":"<p><p>Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors, including abdominal obesity, insulin resistance, dyslipidemia, and hypertension. Its association with venous thromboembolism (VTE) has been inconsistently reported. We investigated the association between MetS and VTE, and the influence of sex and abdominal obesity. We included 12,788 middle-aged and older adults from the re-examination phase of the Swedish prospective cohort Malmö Preventive Project (2002-2006). VTE events were collected using national registers until 31 December 2018. MetS was defined as the presence of three or more of the following factors: abdominal obesity, elevated triglycerides, low high-density lipoprotein cholesterol, hypertension, and impaired fasting glucose. During a mean follow-up of 11 years, 730 first VTE events occurred. The prevalence of MetS was higher in men than in women (p < 0.001). In analyses adjusted for age, height, and smoking, MetS was not associated with increased risk of VTE in men (HR 1.10; 95% CI 0.90-1.34) or women (HR 1.15; 95% CI 0.91-1.45). In women, higher VTE risk was found in those with multiple MetS factors compared to zero. Abdominal obesity was associated with VTE risk in women only (HR 1.80; 95% CI 1.43-2.27). MetS was not associated with VTE risk in men or women. The higher VTE risk observed with multiple MetS components in women appeared largely attributable to abdominal obesity, with little contribution from other components. Risk factors for VTE may differ by sex, with abdominal obesity appearing particularly relevant for women.</p>","PeriodicalId":17546,"journal":{"name":"Journal of Thrombosis and Thrombolysis","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147366007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}