Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-12-10DOI: 10.1097/JU.0000000000004340
J Quentin Clemens
{"title":"Infection and Inflammation of the Genitourinary Tract.","authors":"J Quentin Clemens","doi":"10.1097/JU.0000000000004340","DOIUrl":"10.1097/JU.0000000000004340","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"393-394"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2025-02-07DOI: 10.1097/JU.0000000000004411
{"title":"<i>The Journal of Urology</i><sup>®</sup> Home Study Course 2025 Volume 213/214.","authors":"","doi":"10.1097/JU.0000000000004411","DOIUrl":"https://doi.org/10.1097/JU.0000000000004411","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":"213 3","pages":"401-402"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-10-31DOI: 10.1097/JU.0000000000004309
Sikai Song, Akin S Amasyali, Daniel Jhang, Toby Clark, Kai Wen Cheng, Kyu Park, Nicole Mack, Cliff De Guzman, Ruby Kuang, Matthew Buell, Rose Leu, Kanha Shete, Ala'a Farkouh, Elizabeth A Baldwin, Evan Seibly, Zhamshid Okhunov, D Duane Baldwin
{"title":"Radiating for Two: Quantifying Radiation Exposure to Pregnant Urologists During Percutaneous Nephrolithotomy.","authors":"Sikai Song, Akin S Amasyali, Daniel Jhang, Toby Clark, Kai Wen Cheng, Kyu Park, Nicole Mack, Cliff De Guzman, Ruby Kuang, Matthew Buell, Rose Leu, Kanha Shete, Ala'a Farkouh, Elizabeth A Baldwin, Evan Seibly, Zhamshid Okhunov, D Duane Baldwin","doi":"10.1097/JU.0000000000004309","DOIUrl":"10.1097/JU.0000000000004309","url":null,"abstract":"<p><strong>Purpose: </strong>Current occupational recommendations limit fetal radiation dose to 1 mSv. With increased gender diversity in urology, understanding radiation exposure during pregnancy is crucial. The purpose of this study was to determine surgeon uterine radiation dose during percutaneous nephrolithotomy (PCNL) and compare effectiveness of several radiation reduction strategies in a cadaver model.</p><p><strong>Materials and methods: </strong>Two cadavers were used to simulate the surgeon and the patient in a PCNL model. An ion chamber was placed behind the surgeon's anterior uterine wall to measure the radiation dose. Three radiation reduction methods were compared: pulsed fluoroscopy (1, 4, 8, 15, 30 pulses per second [pps]), low-dose (LD) fluoroscopy, and surgeon shielding (none, 0.35-, 0.50-, 0.70-mm lead equivalents). The average radiation dose per second was recorded for 20 trials per combination. Assuming 5 minutes of fluoroscopy per PCNL, the number of cases required to exceed the fetal occupational limit was determined.</p><p><strong>Results: </strong>Decreasing pulse frequency from 30 to 1 pps reduced the dose by 96% (<i>P</i> < .001). The LD setting decreased the dose by 56% (<i>P</i> < .001). A 0.35-mm lead apron resulted in a 94% dose reduction (<i>P</i> < .001), and the 0.50- and 0.70-mm lead aprons further reduced the dose by 12% and 47%, respectively. In conventional fluoroscopy settings of automatic exposure control and at 30 pps, a surgeon could perform 12 PCNLs using no lead or 189 PCNLs using a 0.35-mm lead apron before reaching the 1-mSv limit. In addition to shielding, using 1 pps with LD fluoroscopy further decreased radiation exposure, allowing over 6000 cases to be performed with < 1 mSv uterine radiation exposure.</p><p><strong>Conclusions: </strong>Within the limitations of this cadaver study, these data support that high-volume pregnant surgeons using active radiation reduction techniques such as pulsed fluoroscopy, LD fluoroscopy, and appropriate shielding can maintain surgical volume with relatively low risk. Fetal dosimeter use with monthly monitoring is still encouraged to confirm safety throughout pregnancy.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"370-377"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-11-11DOI: 10.1097/JU.0000000000004311
Wei Rao, Liangping Zhang
{"title":"Letter: Adults With Spina Bifida Fare Worse Than Young Adults: A Systemic Vulnerability in Urinary Tract Infection-Related Hospital Care.","authors":"Wei Rao, Liangping Zhang","doi":"10.1097/JU.0000000000004311","DOIUrl":"10.1097/JU.0000000000004311","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"378"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-11-19DOI: 10.1097/JU.0000000000004318
Zihan Ye, Hongsong Chen, Xing Liu
{"title":"Letter: Development of a Novel Prediction Tool for Response to First-Line Treatments of Monosymptomatic Nocturnal Enuresis: A Randomized, Controlled, International, Multicenter Study (DRYCHILD).","authors":"Zihan Ye, Hongsong Chen, Xing Liu","doi":"10.1097/JU.0000000000004318","DOIUrl":"10.1097/JU.0000000000004318","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"379"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-11-19DOI: 10.1097/JU.0000000000004331
Phillip M Pierorazio, Nir Kleinmann, Ahmad Shabsigh, Brian Hu, Jay D Raman, Hristos Kaimakliotis, Alexander Sankin, Nirmish Singla, Andrew Meads, Brent Burger, Sunil Raju, Michael J Louie, Karim Chamie, Alon Weizer, Mark Schoenberg
{"title":"Long-Term Outcomes of Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma With UGN-101, a Mitomycin Reverse Thermal Gel.","authors":"Phillip M Pierorazio, Nir Kleinmann, Ahmad Shabsigh, Brian Hu, Jay D Raman, Hristos Kaimakliotis, Alexander Sankin, Nirmish Singla, Andrew Meads, Brent Burger, Sunil Raju, Michael J Louie, Karim Chamie, Alon Weizer, Mark Schoenberg","doi":"10.1097/JU.0000000000004331","DOIUrl":"10.1097/JU.0000000000004331","url":null,"abstract":"<p><strong>Purpose: </strong>We evaluate long-term outcomes of primary chemoablation using a mitomycin reverse thermal gel (UGN-101) in patients with low-grade upper tract urothelial carcinoma.</p><p><strong>Materials and methods: </strong>Patients who participated in the OLYMPUS trial (IRB No. TC-UT-03, NCT02793128) and achieved a complete response (CR) after 6 weekly doses of UGN-101 were followed up to 12 months after initial CR. Those with CR at study completion were eligible for long-term follow-up for up to 5 years or until disease recurrence, progression, or death.</p><p><strong>Results: </strong>Of the 71 patients enrolled in the OLYMPUS trial, 42 patients achieved CR 4 to 6 weeks after completing ≥ 1 instillation of UGN-101. Among the 41 patients followed after initial CR, median follow-up was 28.1 months (95% CI, 13.1-57.5), and median duration of response was 47.8 months (95% CI, 13.0-not estimable [NE]). Twenty patients (49%) had long-term follow-up (median 53.3 months [95% CI, 27.9-65.3]). Seventy-five percent of patients had no evidence of recurrence at the last follow-up, with median duration of response NE (95% CI, 43.5-NE) because of a low event rate.</p><p><strong>Conclusions: </strong>Primary intracavitary chemoablation with UGN-101 for low-grade upper tract urothelial carcinoma is associated with favorable long-term durability.</p><p><strong>Clinical trial registration no.: </strong>NCT02793128.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"313-322"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-12-02DOI: 10.1097/JU.0000000000004332
Cecilie Siggaard Jørgensen, Søren Rittig
{"title":"Reply: Development of a Novel Prediction Tool for Response to First-Line Treatments of Monosymptomatic Nocturnal Enuresis: A Randomized, Controlled, International, Multicenter Study (DRYCHILD).","authors":"Cecilie Siggaard Jørgensen, Søren Rittig","doi":"10.1097/JU.0000000000004332","DOIUrl":"10.1097/JU.0000000000004332","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"381"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-12-05DOI: 10.1097/JU.0000000000004346
Alireza Dehghanmanshadi, Charles C Peyton, Soroush Rais-Bahrami
{"title":"Editorial Comment.","authors":"Alireza Dehghanmanshadi, Charles C Peyton, Soroush Rais-Bahrami","doi":"10.1097/JU.0000000000004346","DOIUrl":"10.1097/JU.0000000000004346","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"321-322"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-12-09DOI: 10.1097/JU.0000000000004341
Dean G Assimos
{"title":"Endourology and Nephrolithiasis.","authors":"Dean G Assimos","doi":"10.1097/JU.0000000000004341","DOIUrl":"10.1097/JU.0000000000004341","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"391-393"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of UrologyPub Date : 2025-03-01Epub Date: 2024-11-13DOI: 10.1097/JU.0000000000004312
Samuel J Ivan, Joshua A Cohn, Jeffrey C Loh-Doyle, Aaron C Lentz, Jay Simhan
{"title":"Cuff Conundrums: Best Practice Recommendations for Urethral Instrumentation With an Artificial Urinary Sphincter in Place.","authors":"Samuel J Ivan, Joshua A Cohn, Jeffrey C Loh-Doyle, Aaron C Lentz, Jay Simhan","doi":"10.1097/JU.0000000000004312","DOIUrl":"10.1097/JU.0000000000004312","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"271-273"},"PeriodicalIF":5.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}