{"title":"Analysis of Risk Prediction Models to Identify Patients at High Risk of Urinary Incontinence","authors":"Rizki Jaya Amal, Suherdy, Delfi Sanutra, Munawmarah, Jevo Rifan Sandikta","doi":"10.59345/sjim.v2i1.110","DOIUrl":"https://doi.org/10.59345/sjim.v2i1.110","url":null,"abstract":"Introduction: Urinary incontinence (UI) is a common health problem and is often undiagnosed in hospital patients. UI can cause complications such as urinary tract infections, dermatitis, and decreased quality of life. This study aims to apply a risk prediction model to identify patients at high risk of experiencing UI at Tengku Peukan General Hospital, Southwest Aceh, Indonesia. \u0000Methods: This study used a prospective cohort design. Data was collected from 100 patients hospitalized at Tengku Peukan General Hospital, Southwest Aceh. A risk prediction model was developed using logistic regression. Model performance is measured by AUC-ROC values and accuracy. \u0000Results: The risk prediction model developed had an AUC-ROC value of 0.85 (95% CI: 0.78-0.92) and an accuracy of 82%. The most significant risk factors for UI are age, gender, history of UI, and use of diuretic medications. \u0000Conclusion: This risk prediction model can help nurses and doctors identify patients who are at high risk of experiencing UI at Tengku Peukan General Hospital, Southwest Aceh. Early intervention in high-risk patients can help prevent UI complications and improve the patient's quality of life.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"134 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140369700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of Life of Coronary Artery Disease Patients Based on the Degree of Physical Ability","authors":"Zuriati Zuriati, Farida Moh. Said","doi":"10.59345/sjim.v2i1.107","DOIUrl":"https://doi.org/10.59345/sjim.v2i1.107","url":null,"abstract":"Introduction: Coronary artery disease (CAD) is a chronic disease that can reduce the patient's quality of life (QoL). Decreased physical ability is one of the factors that can influence the QoL of CAD patients. \u0000Methods: This study used a cross-sectional descriptive design with a sample of 125 CAD patients aged 35-64 years at Dr. M. Djamil General Hospital Padang. QoL data was collected using the WHOQOL-BREF questionnaire, and the degree of physical ability was measured using the Duke Activity Status Index (DASI) questionnaire. Data analysis used the chi-square test. \u0000Results: The results showed that 43.8% of patients had good QoL, and 56.2% had very severe physical abilities. There is a significant relationship between the degree of physical ability and QoL in CAD patients (p-value 0.000). \u0000Conclusion: The degree of physical ability is a predictor of QoL in CAD patients. Interventions to improve physical abilities can help improve QoL in CAD patients.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"53 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the Efficacy of Cardiac Catheterization in Enhancing Blood Circulation in Patients with Coronary Heart Disease: A Systematic Literature Review","authors":"Khomariyana Purnama Sari","doi":"10.59345/sjim.v2i1.102","DOIUrl":"https://doi.org/10.59345/sjim.v2i1.102","url":null,"abstract":"Introduction: Cardiac catheterization is a highly efficient treatment for enhancing blood circulation to the heart in individuals with coronary heart disease (CHD). This operation has the potential to alleviate angina, enhance quality of life, and mitigate the likelihood of myocardial infarction. The objective of this study is to investigate the efficacy of cardiac catheterization in enhancing blood circulation among individuals suffering from CHD. \u0000Methods: We conducted a literature search on multiple databases, including PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar, to investigate the efficacy of cardiac catheterization in enhancing blood circulation among individuals diagnosed with CHD. This study adheres to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) Guidelines. \u0000Results: We identified twenty papers that satisfied the inclusion criteria in this investigation. The research articles were published between 2013 and 2023. The study analysis demonstrates that cardiac catheterization is efficacious in enhancing blood circulation in individuals with CHD. Cardiac catheterization can augment myocardial perfusion by up to 20%. \u0000Conclusion: Cardiac catheterization is more successful in individuals who have mild or moderate stenosis of the coronary arteries. The study analysis indicates that cardiac catheterization is efficacious in enhancing blood circulation in individuals with CHD.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"85 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140484218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preventing Angiotensin Converting Enzyme (ACE)-2 Glycosylation and Protease Activity Disruption as A Means of Safeguarding Against SARS-CoV-2 Infection","authors":"Imran Hasyim, Hery Supratman","doi":"10.59345/sjim.v1i2.77","DOIUrl":"https://doi.org/10.59345/sjim.v1i2.77","url":null,"abstract":"Gastric inhibitory polypeptide (GIP), also known as glucose-dependent insulinotropic polypeptide, is a peptide hormone produced by cells in the small intestine, especially in the duodenum and jejunum. GIP has been a major focus of scientific research due to its important role in regulating the body's response to food intake and controlling blood glucose levels after meals. GIP plays a role in stimulating the release of insulin from beta cells in the pancreas, especially after intake of foods containing glucose or fat. This insulin response is important for optimizing glucose use by body cells and maintaining blood glucose balance, preventing uncontrolled blood glucose spikes.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"50 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139176210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Role of Gastric Inhibitory Polypeptide in the Regulation of Metabolism and Body Physiology","authors":"Novi Margareta","doi":"10.59345/sjim.v1i2.76","DOIUrl":"https://doi.org/10.59345/sjim.v1i2.76","url":null,"abstract":"Gastric inhibitory polypeptide (GIP), also known as glucose-dependent insulinotropic polypeptide, is a peptide hormone produced by cells in the small intestine, especially in the duodenum and jejunum. GIP has been a major focus of scientific research due to its important role in regulating the body's response to food intake and controlling blood glucose levels after meals. GIP plays a role in stimulating the release of insulin from beta cells in the pancreas, especially after intake of foods containing glucose or fat. This insulin response is important for optimizing glucose use by body cells and maintaining blood glucose balance, preventing uncontrolled blood glucose spikes.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutrition and Stem Cell Integrity in Aging: Theory and Implications","authors":"Karolina Gunawan, Aisyah Aulia","doi":"10.59345/sjim.v1i2.75","DOIUrl":"https://doi.org/10.59345/sjim.v1i2.75","url":null,"abstract":"The aging process is a natural phenomenon that involves complex changes in cellular structure and function. The integrity of stem cells, which play a central role in tissue maintenance and regeneration, is affected by various factors, including nutrition. This abstract discusses the role of nutrition in influencing stem cell integrity during aging. Nutrition plays a key role in maintaining the health and normal function of stem cells. Antioxidants such as vitamins C, E, and selenium protect stem cells from oxidative stress and DNA damage, which can compromise regenerative abilities. Anti-inflammatory nutrients such as omega-3 fatty acids and polyphenols help reduce chronic inflammation that can damage the environment in which stem cells operate, maintaining conditions that support regeneration. Apart from that, nutrition also influences the length of telomeres, which protect chromosomes during replication. Folic acid, vitamin B12, and vitamin C play a role in DNA methylation around telomeres, which can influence the maintenance of telomere length and genetic integrity. Aging-related telomere shortening can trigger detrimental genetic changes and disrupt the capabilities of stem cells. A balanced diet, which includes proper nutritional intake, is an important strategy for maintaining healthy stem cells during aging. Reducing the consumption of nutrients that can trigger inflammation and oxidative stress and increasing intake of antioxidant and anti-inflammatory nutrients can help maintain stem cell integrity. Nutritional regulation also plays a role in regulating the signaling pathways that lead to stem cell differentiation, ensuring that stem cells can differentiate into the cell types necessary for tissue repair.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"12 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Update Diagnosis and Treatment of Hemoptysis","authors":"Corey Ingbar","doi":"10.59345/sjim.v1i2.74","DOIUrl":"https://doi.org/10.59345/sjim.v1i2.74","url":null,"abstract":"Hemoptysis refers to the occurrence of bleeding that comes from a location situated below the voice chords. Typically, it is categorized as normal, mild, or major, with the latter referring to bleeding exceeding 200–600 mL (about 1-2 cups) within a 24-hour period. Massive hemoptysis refers to bleeding that is either hemodynamically significant or poses a threat to ventilation. In a single study, the percentage of deaths within the hospital was found to be 6.5%. The primary objective of managing extensive hemoptysis is to provide therapeutic interventions rather than focusing on diagnostic procedures. The majority of occurrences of hemoptysis observed in patients receiving treatment outside of a hospital setting are attributed to infection, such as acute or chronic bronchitis, pneumonia, tuberculosis, or aspergillosis. The purpose of this study is to provide information on the latest advancements in the diagnosis and treatment of hemoptysis symptoms.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"160 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139258122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of Microorganisms Causing Urinary Tract Infections at Cut Meutia General Hospital, North Aceh, Indonesia","authors":"Hidayat Santoso, Zulfikar Ali","doi":"10.59345/sjim.v1i1.17","DOIUrl":"https://doi.org/10.59345/sjim.v1i1.17","url":null,"abstract":"Introduction: Urinary tract infection (UTI) is a general term that refers to the presence of microorganisms in the urine. Bacteria and fungi are the causative agents of urinary tract infections, which can be found in the urine of someone who is indicated to be suffering from a urinary tract infection. This study aimed to provide an overview of microorganisms that cause urinary tract infections in Cut Meutia General Hospital, North Aceh, Indonesia. \u0000Methods: This study is a descriptive observational study. A total of 100 research subjects participated in this study. Data analysis on the distribution of microorganisms that cause UTIs was carried out in a univariate. \u0000Results: The majority of microorganisms that cause urinary tract infections are Escherichia coli. In addition, other microorganisms as the cause of urinary tract infections are Klebsiella pneumoniae, Acinetobacter baumannii, Proteus mirabilis, Klebsiella oxytoca, and Pseudomonas aeruginosa. \u0000Conclusion: Escherichia coli is the most common microorganism that causes urinary tract infections at Cut Meutia General Hospital, North Aceh, Indonesia.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126265516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors of Contrast-Induced Nephropathy in Patients Undergoing Coronary Intervention Procedures","authors":"Ferdayanti Sari, Taufik Sanjaya","doi":"10.59345/sjim.v1i1.16","DOIUrl":"https://doi.org/10.59345/sjim.v1i1.16","url":null,"abstract":"Introduction: Coronary intervention (coronary angiography and percutaneous coronary intervention) is a medical procedure that uses significant amounts of contrast, which can lead to an increased incidence of contrast-induced nephropathy (CIN). This study aimed to determine the risk factors for contrast-induced nephropathy in patients undergoing coronary intervention procedures at Dr. M Djamil General Hospital, Padang, Indonesia. \u0000Methods: This study is a cross-sectional analytic observational study. A total of 100 research subjects participated in this study. Univariate analysis of the frequency distribution was performed on the variable test. Bivariate analysis was performed to determine the risk factors associated with CIN in patients undergoing coronary intervention procedures, p<0.05. \u0000Results: The results of the study showed that contrast volume ≥ 100 ml was associated with the incidence of CIN, p<0.05. In addition, serum creatinine level > 1.5 mg/dL was associated with the incidence of CIN, p<0.05. \u0000Conclusion: Contrast volume ≥ 100 ml and serum creatinine level > 1.5 mg/dl increase the risk of contrast-induced nephropathy in patients undergoing coronary intervention procedures at Dr. M Djamil General Hospital, Padang, Indonesia.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127223767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of Physiological Aspects of Erythropoiesis: A Narrative Literature Review","authors":"Noor Hedayanti, Arif Wahyudi","doi":"10.59345/sjim.v1i1.20","DOIUrl":"https://doi.org/10.59345/sjim.v1i1.20","url":null,"abstract":"Erythropoiesis is the development of red blood cells. Within the confines of the bone marrow, erythroid progenitor cells proliferate and differentiate into large nucleated proerythroblasts, which are committed to producing cells of the erythroid series. This literature review aimed to describe the physiology of erythropoiesis and its application in medical science. All stages of erythroid development are referred to as the erythron. Proerythroblasts, which possess ribosomes and can produce proteins, differentiate through several forms between erythroblasts while synthesizing hemoglobin and progressively removing most of the intracellular structures, including the nucleus. Thus the mature erythroblast becomes more compact and progressively takes on the shape and characteristics of the erythrocyte. Hemoglobin is easily seen, and its amount increases as the size of the nucleus decreases during the basophilic and polychromatophilic stages. The orthochromatic erythroblast (normoblast) is the smallest of the nucleated erythrocyte precursors.","PeriodicalId":173604,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130121849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}