Preventing Angiotensin Converting Enzyme (ACE)-2 Glycosylation and Protease Activity Disruption as A Means of Safeguarding Against SARS-CoV-2 Infection

Abstract

Gastric inhibitory polypeptide (GIP), also known as glucose-dependent insulinotropic polypeptide, is a peptide hormone produced by cells in the small intestine, especially in the duodenum and jejunum. GIP has been a major focus of scientific research due to its important role in regulating the body's response to food intake and controlling blood glucose levels after meals. GIP plays a role in stimulating the release of insulin from beta cells in the pancreas, especially after intake of foods containing glucose or fat. This insulin response is important for optimizing glucose use by body cells and maintaining blood glucose balance, preventing uncontrolled blood glucose spikes.