Journal of the European Academy of Dermatology and Venereology最新文献

{"title":"Trends in cutaneous melanoma mortality and incidence in European Union 15+ countries between 1990 and 2019.","authors":"Xingyue M Wang, Kim Borsky, Dominic W Proctor, Richard Goodall, Dominic C Marshall, William Dobell, Justin D Salciccioli, Rubeta N Matin, Joseph Shalhoub, Naguib El-Muttardi","doi":"10.1111/jdv.20524","DOIUrl":"https://doi.org/10.1111/jdv.20524","url":null,"abstract":"<p><strong>Background: </strong>Cutaneous melanoma (CM) is the leading cause of skin cancer mortality with associated high healthcare costs. Up-to-date reporting of epidemiological trends for CM is required to project future trends, assess the burden of disease and aid evaluation of new diagnostic, therapeutic and preventative strategies.</p><p><strong>Objectives: </strong>To describe the trends in CM mortality, incidence, mortality-to-incidence indices (MIIs) and disability-adjusted life years (DALYs) over the last three decades.</p><p><strong>Methods: </strong>A population-based cross-sectional study of the Global Burden of Disease (GBD) database between 1990 and 2019 was performed. Nineteen high-income countries with similar health expenditure and classified as having high-quality mortality data including the United Kingdom, the United States, Australia and selected European Union countries were included. Annual age-standardized incidence rates (ASIRs), age-standardized death rates (ASDRs) and DALYs for each country were extracted. Mortality-to-incidence indexes were calculated by dividing the ASDR by the ASIR. Trends were described using Joinpoint regression analysis.</p><p><strong>Results: </strong>Almost all countries demonstrated increasing ASDR in males over the observation period with greatest percentage increase in Greece (+87%), and there was greater heterogeneity between countries in females. CM mortality was greater for males than females in all countries. Most recent Joinpoint analysis shows significantly decreasing mortality in all countries except the United Kingdom (+0.5% males between 2007 and 2019, +0.1% females between 2002 and 2019). Incidence rates increased in all countries, with evidence of plateau from 2015 onwards. While MIIs cannot be used as a proxy for survival, statistically significant decreases in MII were observed in all countries. Overall, DALYs remained static.</p><p><strong>Conclusions: </strong>Over the past 30 years, CM mortality and incidence has increased in most EU15+ countries. There is evidence that in recent years, CM mortality is decreasing. The burden of disease as assessed using DALYs has remained mostly unchanged. Future work should not solely focus on expensive innovative therapies, but also on optimizing primary prevention.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in pain interference with daily activities and functional impairment among patients with hidradenitis suppurativa: A population-based study in the United States.","authors":"Paige Kingston, Hannah Peterson, Kathryn Lee, Margaret Y Huang, Danielle Yee, Edwin Korouri, April W Armstrong","doi":"10.1111/jdv.20518","DOIUrl":"https://doi.org/10.1111/jdv.20518","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response-Letter to the Editor: High-frequency ultrasound accuracy in preoperative cutaneous melanoma assessment.","authors":"Georgina E Sellyn, Andrea A Lopez, Shramana Ghosh, Michael C Topf, Heidi Chen, Eric Tkaczyk, Jennifer G Powers","doi":"10.1111/jdv.20465","DOIUrl":"https://doi.org/10.1111/jdv.20465","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of dermoscopic signs of regression in melanocytic lesions with immune checkpoint inhibitor response in metastatic melanoma patients.","authors":"Samy Belkaïd, Marion Clerc, Mona Amini-Adle, Delphine Maucort-Boulch, Stéphane Dalle, Luc Thomas","doi":"10.1111/jdv.20528","DOIUrl":"https://doi.org/10.1111/jdv.20528","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probing into functional decline among bullous pemphigoid patients: Letter in reply.","authors":"Saskia Ingen-Housz-Oro, Raphaël Ouakrat, Émilie Sbidian","doi":"10.1111/jdv.20529","DOIUrl":"https://doi.org/10.1111/jdv.20529","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal association between body fat percentage and hidradenitis suppurativa: A two-sample Mendelian randomization study.","authors":"Dillon Mintoff, Nikolai Pace","doi":"10.1111/jdv.20525","DOIUrl":"https://doi.org/10.1111/jdv.20525","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recibokibart, an anti-IL-36 receptor monoclonal antibody, for treating generalized pustular psoriasis: Phase 1b trial.","authors":"Qiaoxia Qian, Baoqi Yang, Xueyan Lu, Zhaoxia Zhang, Jiaqi Chen, Yehong Kuang, Chunlei Zhang, Xiaoyong Man, Juan Su, Chi Ma, Guodong Zhou, Benke Li, Xiaolu Situ, Xiuqiang Ma, Yongming Yang, Yujie Feng, Shi Chen, Yifan Zhan, Qian Chen, Xiangyang Zhu, Jiucun Wang, Furen Zhang","doi":"10.1111/jdv.20511","DOIUrl":"https://doi.org/10.1111/jdv.20511","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of light dose and fluence rate on the efficacy and tolerability of topical 5-ALA photodynamic therapy for actinic keratoses: A randomized, controlled, observer-blinded intrapatient comparison study.","authors":"Adrian Tanew, Robin Ristl, Hannes Trattner, Valentin Hacker, Bettina Kroyer, Sonja Radakovic","doi":"10.1111/jdv.20527","DOIUrl":"https://doi.org/10.1111/jdv.20527","url":null,"abstract":"<p><strong>Background: </strong>Conventional photodynamic therapy (cPDT) is an effective treatment option for field cancerization and multiple actinic keratoses (AK). The main side effect of cPDT is pain during illumination which in severe cases might necessitate early termination of treatment. Modification of treatment parameters such as light dose and fluence rate is a promising approach to mitigate PDT-associated pain.</p><p><strong>Objectives: </strong>The aim of this study was to compare the efficacy and tolerability of four different cPDT illumination protocols in the treatment of AK in the head region.</p><p><strong>Methods: </strong>Prospective, investigator-blinded, within-patient study on 67 patients with multiple AK in the head region. PDT treatment was performed on comparable target areas with four different settings of illumination: (A) standard light dose and standard fluence rate, (B) standard light dose and halved fluence rate, (C) halved standard light dose and standard fluence rate and (D) halved standard light dose and halved fluence rate. Pain and the intensity of the phototoxic skin reaction was recorded during and after illumination. The clearance rate of the target areas and target lesions was assessed at 12 weeks after PDT. Target areas with incomplete clearance were retreated, those with complete clearance were reassessed at 24 weeks after PDT.</p><p><strong>Results: </strong>The mean and maximum pain level during illumination was significantly decreased at the lower fluence rates. The phototoxic skin reaction was most pronounced with the standard illumination setting. The overall clearance rate of AK and the clearance rate of the target lesions at 3 months after PDT as well as the number of recurrent or new AK at 6 months after PDT did not differ between four treatment protocols.</p><p><strong>Conclusions: </strong>Reduction of the fluence rate and/or light dose was associated with less PDT-induced pain and/or shorter exposures times without compromising the therapeutic efficacy of cPDT for AK in the head region.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of dupilumab on sleep disruptions in patients with prurigo nodularis: A systematic review and meta analysis.","authors":"Dea Metko, Shanti Mehta, Parsa Abdi, Owen D Lyons, Vincent Piguet","doi":"10.1111/jdv.20495","DOIUrl":"https://doi.org/10.1111/jdv.20495","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium chelonae cutaneous infections unrelated to invasive procedures: A multicentre retrospective case series.","authors":"Alicia Leymarie, Pascal Thibon, Charlotte Bernigaud, Claire Daurel, Elise Ouedraogo, Coralie Lheure, Nadine Lemaitre, Bernard Cribier, Andreea Calugareanu, Emilie Ducroux, Sophie Baron, Clélia Vanhaecke, Margot Lehericey, Elisa Goujon, Tanguy Allard, Sébastien Fouéré, Anne Dompmartin, Olivier Chosidow, Jérôme Robert, Emmanuelle Cambau, Nicolas Dupin, Renaud Verdon, Diane Kottler","doi":"10.1111/jdv.20521","DOIUrl":"https://doi.org/10.1111/jdv.20521","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}