Journal of the European Academy of Dermatology and Venereology最新文献

{"title":"Sexual orientation and gender identity in clinical trials of atopic dermatitis and psoriasis.","authors":"Michael J Martinez, Corinne Rabbin-Birnbaum, Howa Yeung, John G Zampella","doi":"10.1111/jdv.20742","DOIUrl":"https://doi.org/10.1111/jdv.20742","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of adalimumab-induced psoriasis in hidradenitis suppurativa versus other inflammatory diseases.","authors":"Tung S Tran, Anh B Q Nguyen, Trang M Nguyen, Edward V Loftus, Courtney A Arment, Doanh H Le, Afsaneh Alavi, David A Wetter, Giang H Nguyen","doi":"10.1111/jdv.20743","DOIUrl":"https://doi.org/10.1111/jdv.20743","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An adhesive magnetic tray for on-surgical-table needle management.","authors":"Guoqun Yu, Fan Yang, Liu Yang, Yamin Zhang, Juan Tao","doi":"10.1111/jdv.20749","DOIUrl":"https://doi.org/10.1111/jdv.20749","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inter- and intra-observer agreement among dermatologists in assessing suspected melanoma lesions captured by general practitioners with smartphones.","authors":"Edmond Démoulins, Heloïse Schmeltz, Aurélie Gaultier, Jean Michel Nguyen, Gaëlle Quereux, Brigitte Dreno, Ludovic Martin, Cédric Rat","doi":"10.1111/jdv.20726","DOIUrl":"https://doi.org/10.1111/jdv.20726","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world efficacy and safety of baricitinib combined with corticosteroids in alopecia areata.","authors":"Jorge Naharro-Rodríguez, Emilio Berna-Rico, Ángela Hermosa-Gelbard, Diego Buendía-Castaño, Sergio Vañó-Galván, David Saceda-Corralo","doi":"10.1111/jdv.20747","DOIUrl":"https://doi.org/10.1111/jdv.20747","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omalizumab dosing patterns and drug survival in adult patients with chronic spontaneous urticaria","authors":"Ditte Georgina Zhang,&nbsp;Mia-Louise Nielsen,&nbsp;Jennifer Astrup Sørensen,&nbsp;Somaia Naassan,&nbsp;Christian Vestergaard,&nbsp;Emek Kocatürk,&nbsp;Zarqa Ali,&nbsp;Jacob P. Thyssen,&nbsp;Alexander Egeberg,&nbsp;Simon Francis Thomsen","doi":"10.1111/jdv.20737","DOIUrl":"10.1111/jdv.20737","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Omalizumab is an effective treatment for chronic spontaneous urticaria (CSU), but strategies and predictors for guiding long-term management and discontinuation remain limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To examine real-world treatment patterns, including dosing modifications and discontinuation, and identify potential predictive factors for these outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a retrospective, observational, real-life study of adult patients with CSU treated with omalizumab at a Urticaria Center of Reference and Excellence (UCARE) in Copenhagen, Denmark, between May 20, 2015, and April 4, 2024. The Kaplan-Meier estimator was used to visualize time to discontinuation and dose escalation/reduction (using standard label dosing as reference), and Cox-regressions with hazard ratios (HR) were used to investigate potential predictive variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 430 patients initiated on omalizumab, 139 (32.4%) escalated treatment, 161 (37.5%) reduced treatment, and 90 (21.0%) discontinued treatment directly from the standard dose. The median survival time for dose escalation was 2 years (95% CI: 1.17–3.55), and the strongest predictor was a positive basophil histamine release assay (BHRA) (HR: 2.79, 95% CI: 1.69–4.61). Fast treatment response (HR: 0.50, 95% CI: 0.33–0.75) and higher baseline UCT scores (HR: 0.89, 95% CI: 0.82–0.97) decreased the risk of dose escalation. The median survival time to dose reduction was 1.2 years (95% CI: 0.98–1.49) and was more likely in males (HR: 1.68, 95% CI: 1.13–2.50) and patients with fast treatment response (HR: 1.66, 95% CI: 1.12–2.48). Median survival time to discontinuation (all reasons) of omalizumab was 3 years (95% CI: 2.35–3.64).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A considerable proportion of patients with CSU require modifications to the recommended omalizumab dosing regimen. A positive BHRA was the strongest predictor for dose escalation, while male sex and fast treatment response were the strongest predictors for dose reduction. Our study highlights the need for individualized strategies in managing CSU.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":"39 10","pages":"1796-1805"},"PeriodicalIF":8.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond vancomycin: Pharmacovigilance detects new drugs involved in linear IgA bullous dermatosis.","authors":"Manon Roques, François Montastruc, Marion Marcaillou, Chloé Challamel, Bénédicte Lebrun-Vignes, Claire de Canecaude, Romain Barus","doi":"10.1111/jdv.20745","DOIUrl":"https://doi.org/10.1111/jdv.20745","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic failure in leprosy, French Guiana, 2011-2024: Impact of bacillary index.","authors":"Quiterie Boscals de Réals, Juliette Lebret, Kinan Drak Alsibai, Romain Blaizot, Geoffrey Grotta","doi":"10.1111/jdv.20744","DOIUrl":"https://doi.org/10.1111/jdv.20744","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture risk among adults with atopic dermatitis: A population-based cohort study in the United Kingdom","authors":"Zelma C. Chiesa Fuxench,&nbsp;Joy Wan,&nbsp;Sonia Wang,&nbsp;Maha N. Syed,&nbsp;Daniel B. Shin,&nbsp;Katrina Abuabara,&nbsp;Adina R. Lemeshow,&nbsp;Joel M. Gelfand","doi":"10.1111/jdv.20728","DOIUrl":"10.1111/jdv.20728","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":"39 9","pages":"e816-e819"},"PeriodicalIF":8.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constraints of using Dermatology Life Quality Index as a benchmark for new quality of life measures: An interpretive viewpoint","authors":"Melih Akyol,&nbsp;Rukiye Yasak Guner,&nbsp;Mustafa Tosun","doi":"10.1111/jdv.20732","DOIUrl":"10.1111/jdv.20732","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":"39 10","pages":"e938-e939"},"PeriodicalIF":8.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}