Journal of the International Association of Providers of AIDS Care最新文献

{"title":"Advanced HIV Disease at Antiretroviral Therapy Initiation and Treatment Outcomes Among Children and Adolescents Compared to Adults Living With HIV in Kinshasa, Democratic Republic of the Congo.","authors":"Otto Nzapfurundi Chabikuli, John D Ditekemena, Lovemore Nyasha Sigwadhi, Astrid Mulenga, Aimé Mboyo, Dieudonne Bidashimwa, Jean B Nachega","doi":"10.1177/23259582231221955","DOIUrl":"10.1177/23259582231221955","url":null,"abstract":"<p><p><b>Background:</b> Little is known about advanced HIV disease (AHD) at antiretroviral therapy (ART) initiation among children and adolescents living with HIV (CALHIV) and related age disparities in the Democratic Republic of the Congo (DRC). <b>Methods:</b> We conducted a retrospective cohort analysis of routine program data collected among adults, adolescents, and children living with HIV in 6 health zones in Kinshasa, DRC from 2005 to 2020. <b>Results:</b> Thirty-two percent of those who initiated ART had AHD. Compared to adults, adolescents had a 15% higher risk of AHD (RR: 1.15; 95% CI: 1.08-1.21; <i>P < </i>.001). Despite their higher risk of AHD, adolescents had a lower risk of mortality (aSHR: 0.72; 95% CI: 0.52-0.99; <i>P </i>= .047) and lower cumulative death events versus adults (aSHR: 0.44; 95% CI: 0.34-0.59; <i>P</i> < .001). <b>Conclusions:</b> ADH at ART initiation is highly prevalent in Kinshasa, DRC, and adolescents are disproportionally impacted. There is a need to scale up high-impact HIV interventions targeting CALHIV.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231221955"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10752042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"It's Still in the Test Tube and Finding out How the Experiment Ends… \". A Qualitative Study on Health and Aging in Older Gay Males Living with HIV in England.","authors":"Stefano Licchelli,&nbsp;Andrew King,&nbsp;Kimberley J Smith","doi":"10.1177/23259582221144448","DOIUrl":"https://doi.org/10.1177/23259582221144448","url":null,"abstract":"<p><p>This paper highlights experiences and perceptions of older gay males living with Human Immunodeficiency Virus (HIV) in relation to age, sexual orientation, HIV status and how they perceive health. Participants were gay males aged 50 and over living in England, diagnosed with HIV for longer than 2 years. In total, 19 interviews were conducted between March 2020 and March 2021. Data were analysed using thematic analysis. Three major themes were generated: 1.) Health as holistic and as a balance; 2.) The impact of HIV on people's lives; 3.) The Intersectionality of stigma: a lifetime of discrimination. Participants highlighted the changing nature of the concept of health through their lifespan while the intersectionality of stigma in different contexts is examined considering the personal journey of living with HIV. The implications of health as a complex concept and intersectional stigma on the planning and delivering of care in this population are discussed.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582221144448"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"You Almost Feel Out of Touch [For Saying] … 'Oh, and by the way, Stop Smoking.'\" A Qualitative Exploration of Provider Perspectives About Discussing Tobacco and Cannabis Use With 18-24-Year-Old Young Adults With HIV.","authors":"Samantha V Hill, Paige Palenski, Heidi M Crane, Conall O'Cleirigh, Lynn T Matthews, Karen Cropsey","doi":"10.1177/23259582231163125","DOIUrl":"10.1177/23259582231163125","url":null,"abstract":"<p><p><b>Background:</b> Youth with HIV (YWH) aged 18-24 are overburdened by tobacco, with half also using cannabis recreationally. Increasing tobacco cessation necessitates exploring providers' approaches to cessation. <b>Methods:</b> Grounded in social cognitive theory, we explored cognitive, socioenvironmental, and behavioral factors impacting providers' approaches to tobacco use among recreational cannabis users. Virtual interviews were conducted among healthcare providers caring for YWH in Washington (legalized cannabis), Massachusetts (legalized cannabis), and Alabama (cannabis not legal). Interviews were transcribed and analyzed via deductive and exploratory, thematic approaches using NVivo 12 Plus. <b>Results:</b> Twelve providers participated; 80% were subspecialist physicians. All providers (<i>N</i> = 12) reported discussing tobacco use; none reported discussing tobacco use in conjunction with cannabis use. Identified themes included competing demands including cannabis co-use, prioritization of social determinants of health, and need for youth-tailored tools. <b>Conclusions:</b> YWH disproportionately use tobacco and recreational cannabis. Optimizing clinical visits to identify opportunities to address tobacco is crucial.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231163125"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/8a/10.1177_23259582231163125.PMC10074605.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9684953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathways Between Intersectional Stigma and HIV Treatment Engagement Among Men Who Have Sex with Men (MSM) in India.","authors":"Kiran Bhutada, Venkatesan Chakrapani, Fazlur R Gulfam, Jonathan Ross, Sarit A Golub, Steven A Safren, Rita Prasad, Viraj V Patel","doi":"10.1177/23259582231199398","DOIUrl":"10.1177/23259582231199398","url":null,"abstract":"<p><p>In India and other low-and-middle-income countries, little is known about how intersectional stigma affects MSM engagement in ART. Informed by the Health Stigma and Discrimination Framework, we qualitatively examined how multiple stigmas influence ART engagement among Indian MSM. We conducted 3 focus groups (N = 22) with MSM living with HIV, aged 21-58 years, in Delhi and Hyderabad to identify potential intervention targets and solutions to improve treatment outcomes. Framework analysis and techniques were used to code and analyze translated audio-recordings. Findings revealed enacted stigma, associated with HIV and MSM identity, manifested as familial shame and healthcare discrimination, inhibiting access to support, and decreasing HIV care engagement. Anticipated stigma led to worry about disclosure and societal repercussions. Community-Based-Organizations, ART centers, and family members were primary sources of support, leading to increased ART initiation and retention. Potential solutions included using MSM peer-counselors, increasing social support, and providing HIV education to the general community.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231199398"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/ea/10.1177_23259582231199398.PMC10501078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10258554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black Adolescent Females' Perceptions of PrEP for HIV Risk Reduction.","authors":"Mariana Budge, Ijeoma Opara, Veronica U Weser, Brandon E Sands, Kimberly D Hieftje","doi":"10.1177/23259582231206934","DOIUrl":"10.1177/23259582231206934","url":null,"abstract":"<p><p>Preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) prevention is approved for use in adolescents, though uptake remains low. Black adolescent females experience higher rates of HIV transmission compared to adolescent females of other racial/ethnic groups. Increasing PrEP awareness and education among this population may be an effective strategy to mitigate disparities in HIV transmission among Black adolescent females. Twenty-seven Black adolescent females participated in focus groups which were coded using the constant comparative method of qualitative analysis to identify major themes: (1) PrEP is not commonly framed as an HIV prevention strategy for heterosexual Black adolescent females, (2) PrEP use among peers is perceived as mostly positive, (3) Adoption of PrEP among Black adolescent females is impeded by perceived barriers such as stigma, negative side effects, and adherence concerns. These findings may inform the development of targeted culturally tailored marketing and educational campaigns centered on Black heterosexual adolescent females to increase PrEP awareness and uptake in this population disproportionately affected by HIV.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231206934"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/26/10.1177_23259582231206934.PMC10588402.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49678911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HCV Genotype Distribution and Clinical Characteristics of HCV Mono-Infected and HCV/HIV Co-Infected Patients in Liangshan Prefecture, Sichuan Province, China.","authors":"Bianchuan Cao, Mei Liu, Tao Jiang, Qinghua Yu, Tianru Yuan, Ping Ding, Xian Zhou, Yongmao Huang, Yongsheng Zou, Fuli Huang","doi":"10.1177/23259582231217810","DOIUrl":"10.1177/23259582231217810","url":null,"abstract":"<p><p><b>Objective:</b> The present study aimed to characterize the genotype distribution and clinical characteristics of HCV monoinfected and HCV/HIV coinfected patients in the Liangshan Prefecture, Sichuan Province, China. <b>Methods:</b> All the patients were divided into HCV monoinfection and HCV/HIV coinfection groups according to whether they were complicated with HIV infection. The data from the two groups were collected. <b>Results:</b> In this study, HCV genotype 3 was the most common genotype in both groups, while HCV genotype 6 was significantly higher in the coinfection group than in the monoinfection group (<i>p </i>= 0.046). The white blood cell count, total bilirubin level, and HCV RNA were significantly higher in the HCV monoinfection group than that in the HCV/HIV coinfection group (<i>p </i>= 0.031; <i>p </i>< 0.001; <i>p </i>= 0.027, respectively). <b>Conclusion:</b> HCV prevalence was high in HIV-positive patients in the Liangshan Prefecture. Thus, incorporating screening and management of HCV monoinfection and HCV/HIV coinfection is needed in local region programs.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231217810"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138804445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PrEP Acceptance among Eligible Patients Attending the Largest PrEP Clinic in Jackson, Mississippi.","authors":"Madison R Hollcroft, June Gipson, Alicia Barnes, Leandro Mena, Julia C Dombrowski, Lori M Ward, Christine M Khosropour","doi":"10.1177/23259582231167959","DOIUrl":"10.1177/23259582231167959","url":null,"abstract":"<p><p>Compared to other states in the United States, Mississippi has the lowest uptake of PrEP relative to the number of people newly diagnosed with HIV in the state. Open Arms Healthcare Center is the largest provider of PrEP in Mississippi, and has systematically documented PrEP eligibility, offers, and acceptance (ie, agreed to undergo a clinical PrEP evaluation) from 2017 to mid-2020. In encounter-based analyses, we examined factors associated with PrEP acceptance. Among 721 encounters where patients were eligible for PrEP, staff offered PrEP at 680 (94%) of encounters (526 unique individuals); individuals accepted a PrEP offer at 58% of encounters. Accepting a PrEP offer was lowest (15.8%) among transgender/non-binary individuals and highest (93.3%) among individuals who reported having sex partners living with HIV. This clinic's model worked to offer PrEP to a highly impacted population, though there is a need to enhance PrEP acceptance for key groups such as transgender/non-binary individuals.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231167959"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/6b/10.1177_23259582231167959.PMC10088405.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Cohort Study Comparing Antiretroviral Treatment Outcomes Among Adolescents in Teen Clubs and Standard Care Clinics: Blantyre, Malawi.","authors":"Michael Alibi,&nbsp;Victor Mwapasa,&nbsp;Fatsani Ngwalangwa","doi":"10.1177/23259582231172340","DOIUrl":"https://doi.org/10.1177/23259582231172340","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigated if the Teen Club model improves virological suppression and reduces virological failure. Viral load monitoring is a golden ART programme performance indicator. HIV treatment outcomes are poor among adolescents compared to adults. Different service delivery models are being implemented to address this; among them is the Teen Club model. Currently, teen clubs improve treatment adherence (short-term impact), but there is a knowledge gap regarding the long-term impact. The study compared the rate of virological suppression and failure among adolescents in Teen Clubs and those on the standard of care (SoC) model.</p><p><strong>Methods: </strong>This was a retrospective cohort study. A total of 110 adolescents in teen clubs and 123 adolescents in SOC from six health facilities were selected using stratified simple random sampling. The participants were followed for 24 months. STATA version 16.0 was used for data analysis. Univariate analyses were performed for both demographic and clinical variables. A Chi-squared test was used to assess the differences between proportions. Crude and adjusted relative risks were calculated using a binomial regression model.</p><p><strong>Results: </strong>At 24 months, 56% of adolescents in the SoC arm had viral load suppression compared to 90% in the Teen Club arm. Of those who achieved viral load suppression at 24 months, about 22.7% (SoC) and 76.4% (Teen Club) achieved undetectable viral load suppression rates. Adolescents in the Teen Club arm had a lower viral load than those in the SoC arm (adjusted RR 0.23, 95% CI: 0.11-0.61; <i>p</i>  =  0.002 adjusted for age and gender). Teen Club and SoC adolescents had virological failure rates of 3.1% and 10.9%, respectively. The adjusted RR was 0.16, 95% CI: 0.03-0.78; <i>p</i>  =  0.023; those in Teen Clubs were less likely to have virological failure relative to those in SoC after adjusting for age, sex, and place of residence.</p><p><strong>Conclusion: </strong>The study found that Teen Club models are more effective at achieving virological suppression among HIV positive adolescents.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231172340"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/a0/10.1177_23259582231172340.PMC10196531.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Reliability of the Human Immunodeficiency Virus-Related Stigma Questionnaire in Persian.","authors":"Rahmatollah Moradzadeh, Iman Navidi, Maryam Zamanian","doi":"10.1177/23259582231189094","DOIUrl":"10.1177/23259582231189094","url":null,"abstract":"<p><p><b>Background:</b> It was aimed to adapt a 12-item questionnaire into Persian among people living with human immunodeficiency virus (PLHIV) in Markazi province. <b>Material and Methods:</b> Content validity was evaluated based on the opinions of the relevant experts, and by calculating the scale-level content validity index (S-CVI) and the item-level content validity index (I-CVI). Reliability was assessed via test-retest, intraclass correlation coefficient (ICC), and Cronbach's alpha. <b>Results:</b> The obtained scores on clarity and relevancy (I-CVI) ranged from 0.9 to 1. The S-CVI also had an acceptable validity of 0.99. The Cronbach's alpha index of the whole questionnaire was 0.84 and ranged from 0.69 to 0.82 for subscales. The ICC in test-retest for all questionnaires was 0.88 and for subscales ranged from 0.77 to 0.88. <b>Conclusion:</b> The Persian version of the 12-item human immunodeficiency virus-related stigma questionnaire was found to be, in addition to being short and comprehensive, acceptable reliability and high validity to use in order to determine the stigma related to Persian-speaker PLHIV.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231189094"},"PeriodicalIF":2.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/43/78/10.1177_23259582231189094.PMC10395164.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Patients' Satisfaction with Pharmaceutical Care at a Nigerian Tertiary Healthcare Facility During the Covid-19 Pandemic.","authors":"Dalhatu Muhammad Ahmad,&nbsp;Emmanuel Ebuka Abonyi,&nbsp;Joseph Chukwudi Ugwuonah,&nbsp;Peter Esin Okon,&nbsp;Shuaibu Aliyu,&nbsp;Leonard Ighodalo Uzairue Bmls MSc,&nbsp;Don Eliseo Lucero-Prisno","doi":"10.1177/23259582231159093","DOIUrl":"https://doi.org/10.1177/23259582231159093","url":null,"abstract":"<p><p><b>Background:</b> Patients' satisfaction is an important indicator of determining the quality of pharmaceutical care (PC). This study investigated Human Immunodeficiency Virus (HIV) patients' satisfaction with PC at Federal Medical Centre, Keffi-Nigeria and determined the statistical correlation between the respondents' socio-demographic variables and their satisfaction with PC. <b>Methods:</b> This cross-sectional survey study involved 351 randomly selected HIV-positive patients receiving PC in the facility. A Likert-type questionnaire was used for the data collection. <b>Results:</b> The Cronbach's alpha of the questionnaire was .916. The \"overall perception of pharmacists' care or service\" had a mean satisfaction score of 4.24 ± 0.749 and \"the amount of time spent with the pharmacists\" had a mean score of 3.94 ± 0.791. No significant association was found between socio-demographic variables and overall patients' satisfaction with PC. <b>Conclusion:</b> The reliability of the questionnaire was high and the HIV patients had a good satisfaction with the PC they received in the facility.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"22 ","pages":"23259582231159093"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/46/d7/10.1177_23259582231159093.PMC9989440.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9428508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}