{"title":"Comment on \"Integrating traditional Chinese Medicine reduced the risk of hip fracture in patients with dementia\".","authors":"Weichu Sun","doi":"10.1016/j.jfma.2025.09.026","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.026","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electrolyte trajectories in chronic kidney disease primary Care: An 11-year follow-up study.","authors":"Chien-Hung Lin, Mu-Chi Chung, Chen-Yu Yeh, Laing-You Wu, Tsung-Hsien Chen, Peir-Haur Hung, Chi-Jung Chung","doi":"10.1016/j.jfma.2025.09.025","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.025","url":null,"abstract":"<p><strong>Background and aims: </strong>Long-term disturbances in mineral metabolism and their effects on chronic kidney disease (CKD) outcomes remain unclear. This study aimed to investigate whether longitudinal trajectories of sodium (Na), potassium (K), calcium (Ca), and phosphorus (P) are associated with the risk of progressing to dialysis.</p><p><strong>Methods: </strong>We conducted a longitudinal cohort study including 2978 pre-dialysis CKD patients aged ≥18 years. Patients were stratified into four groups using group-based multi-trajectory modeling based on changes in serum Na, K, Ca, and P. The association between these trajectory groups and incident dialysis was assessed using Cox proportional hazards regression models, adjusted for baseline estimated glomerular filtration rate (eGFR) and other potential confounders.</p><p><strong>Results: </strong>The mean age of the cohort was 70.02 years, with a median follow-up duration of 2.86 years. Patients in Group 3-characterized by higher K and P and lower Na and Ca-had a 3.68-fold higher risk of initiating dialysis compared to Group 1, with an average annual eGFR decline of -2.6 mL/min/1.73 m<sup>2</sup> (p < 0.0001). In sensitivity analyses limited to patients with CKD stage 3b, similar associations were observed. Furthermore, multi-electrolyte trajectories in the first 3 years were predictive of dialysis risk over the subsequent 2 years (hazard ratio = 3.41; 95 % CI: 1.02-11.40) in Group 3 versus Group 1.</p><p><strong>Conclusions: </strong>Longitudinal changes in serum Na, K, Ca, and P levels-especially within the first three years-are associated with increased risk of dialysis in CKD patients. Early identification of adverse electrolyte patterns may inform timely interventions to delay disease progression.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shwu Jen Lin, Yao Wen Kuo, Huey Dong Wu, Shih Hsing Yang
{"title":"The association between pre-discharge factors and early unplanned readmissions in adult home mechanical ventilation patients in Taiwan.","authors":"Shwu Jen Lin, Yao Wen Kuo, Huey Dong Wu, Shih Hsing Yang","doi":"10.1016/j.jfma.2025.09.021","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.021","url":null,"abstract":"<p><strong>Background: </strong>Purpose: Home mechanical ventilation offers significant benefits, but hospital readmissions remain a challenge, with rates as high as 20-40 % and associated mortality. While some studies have investigated risk factors for readmission, pre-discharge factors influencing unplanned readmissions in this population remain unclear. This study aimed to identify pre-discharge factors associated with unplanned hospital readmissions in home-ventilated patients.</p><p><strong>Methods: </strong>A 60-month retrospective cohort study was conducted, including patients receiving home mechanical ventilation. Demographic, respiratory, physiological, and laboratory parameters near discharge were collected. Readmissions were categorized as occurring within 30 days and beyond to identify pre-discharge factors associated with unplanned hospital readmissions.</p><p><strong>Results: </strong>Among a cohort of 6925 mechanically ventilated patients, 913 were readmitted. Of these, 127 were unplanned readmissions, with an average age of 70 years, predominantly female (68 subjects), and 33.1 % occurred within 30 days post-discharge. Logistic regression analysis identified cardiovascular disease, maximum inspiratory pressure, and low hemoglobin levels as significant predictors of early unplanned readmissions within 30 days.</p><p><strong>Conclusion: </strong>Unplanned hospital readmissions pose a considerable challenge for home-ventilated patients, particularly within the first 30 days post-discharge. Pre-discharge factors, including cardiovascular disease, low inspiratory muscle performance as assessed by PImax, and low hemoglobin levels, are key risk factors. Addressing these factors during discharge planning is crucial to reducing early readmissions and improving patient outcomes and resource allocation in healthcare.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive factors and survival associated with varying degrees of cytopenia in patients undergoing chronic Hemodialysis: A cohort study.","authors":"Wei Wang, Pin-Han Wu, Chien-Yuan Chen, Shih-I Chen, Chiung-Ying Huang, Yi-Chih Lin, Chih-Kang Chiang, Yung-Ming Chen, Yu-Hsiang Chou","doi":"10.1016/j.jfma.2025.09.023","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.023","url":null,"abstract":"<p><strong>Background: </strong>Anemia and other hematologic abnormalities are common among patients undergoing chronic hemodialysis. Early identification of predictive factors associated with hemogram abnormalities is crucial, as these factors may be linked to overall survival and hematologic disorders.</p><p><strong>Method: </strong>In March 2021, a total of 478 patients with end-stage renal disease undergoing chronic hemodialysis were enrolled. Cytopenia was categorized into four groups: normal hemogram, single cytopenia, bicytopenia, and pancytopenia. Multivariate analyses were conducted to identify predictive factors for hemogram abnormalities. Survival analysis was performed to evaluate the overall survival of patients with varying degrees of cytopenia over a mean follow-up period of 3.3 years.</p><p><strong>Results: </strong>Multivariate analyses demonstrated that bicytopenia or pancytopenia was associated with a higher erythropoiesis-stimulating agent resistance index (ERI) (p = 0.007) and serum ferritin levels (p = 0.039). A significant difference in three-year survival was observed between patients with a normal hemogram and those with single cytopenia (p = 0.027), whereas no significant difference was found between patients with single cytopenia and those with either bicytopenia or pancytopenia (p = 0.266). Among patients with the longest duration of dialysis, the presence of any degree of cytopenia was significantly associated with poorer survival outcomes compared to those with a normal hemogram (p = 0.046).</p><p><strong>Conclusions: </strong>In our study, bicytopenia or pancytopenia in patients undergoing chronic hemodialysis was associated with a higher ERI and elevated serum ferritin levels. In addition, any degree of cytopenia was linked to poorer overall survival among patients with the longest duration of dialysis.</p>","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Right ventricular pacing burden and progression of renal failure in chronic kidney disease patients with permanent pacemakers\": Right ventricular pacing burden and renal failure.","authors":"Xiangquan Tian, Li Luo, Juan Wang, Peng Chen","doi":"10.1016/j.jfma.2025.09.019","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.019","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward a Taiwanese vision for health-care professionals: Reimagining workforce sustainability.","authors":"Hsuan Huang, Yi-Hsin Lin","doi":"10.1016/j.jfma.2025.09.020","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.020","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on Impact of amiodarone on plasma concentration of direct oral anticoagulant in patients with atrial fibrillation.","authors":"Gao Zhanyi, Wei Yuejuan","doi":"10.1016/j.jfma.2025.09.011","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.011","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on Impact of type D personality on clinical outcomes in Asian patients with stable coronary artery disease.","authors":"Deng Lvyu, Xia Zhonggen, Gan Daohui, Luo Biao","doi":"10.1016/j.jfma.2025.09.015","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.015","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Pregnancy and perinatal outcomes of mothers with inflammatory bowel disease in Taiwan: A national database analysis\".","authors":"Caifeng Yu, Qinxin Pan, Honglei Wang","doi":"10.1016/j.jfma.2025.09.001","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.001","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to comment on \"Controlling nutritional status score as a survival prognosticator in patients with head and neck cancer\".","authors":"Ming-Hsien Tsai, Chih-Yen Chien, Hui Lu, Fu-Min Fang","doi":"10.1016/j.jfma.2025.09.017","DOIUrl":"https://doi.org/10.1016/j.jfma.2025.09.017","url":null,"abstract":"","PeriodicalId":17305,"journal":{"name":"Journal of the Formosan Medical Association","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}