发布求助
文献互助 智能选刊 最新文献

Journal of The American Society of Nephrology最新文献

筛选
英文 中文
Authors' Reply: Eligibility for Predialysis Care and Effect on Patient Outcomes in Ontario Needs Further Study. 作者回复：安大略省透析前护理的资格和对患者预后的影响需要进一步研究。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-19 DOI: 10.1681/ASN.0000001280
Amber O Molnar, K Scott Brimble, Peter G Blake, Arsh K Jain
{"title":"Authors' Reply: Eligibility for Predialysis Care and Effect on Patient Outcomes in Ontario Needs Further Study.","authors":"Amber O Molnar, K Scott Brimble, Peter G Blake, Arsh K Jain","doi":"10.1681/ASN.0000001280","DOIUrl":"https://doi.org/10.1681/ASN.0000001280","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eligibility for Predialysis Care and Effect on Patient Outcomes in Ontario Needs Further Study. 安大略省透析前护理的资格及其对患者预后的影响需要进一步研究。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-19 DOI: 10.1681/ASN.0000001279
Albert Kadri
{"title":"Eligibility for Predialysis Care and Effect on Patient Outcomes in Ontario Needs Further Study.","authors":"Albert Kadri","doi":"10.1681/ASN.0000001279","DOIUrl":"https://doi.org/10.1681/ASN.0000001279","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Ultrasound Localization Microscopy to Assess the Intrarenal Microvasculature in Autosomal Dominant Polycystic Kidney Disease. 修正：超声定位显微镜评估常染色体显性多囊肾病肾内微血管。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-19 DOI: 10.1681/ASN.0000001307
Chengwu Huang, Ahmed Abdelfattah, Ryan M DeRuiter, Nathan Zhang, Kate M Knoll, Kendra E Petersen, Tao Wu, Youwen Zhang, Marie C Hogan, Alfonso Eirin, Lilach O Lerman, Shigao Chen, Maria V Irazabal
{"title":"Correction to: Ultrasound Localization Microscopy to Assess the Intrarenal Microvasculature in Autosomal Dominant Polycystic Kidney Disease.","authors":"Chengwu Huang, Ahmed Abdelfattah, Ryan M DeRuiter, Nathan Zhang, Kate M Knoll, Kendra E Petersen, Tao Wu, Youwen Zhang, Marie C Hogan, Alfonso Eirin, Lilach O Lerman, Shigao Chen, Maria V Irazabal","doi":"10.1681/ASN.0000001307","DOIUrl":"https://doi.org/10.1681/ASN.0000001307","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucagon-Like Peptide-1 Receptor Agonists and Multi-hormone Receptor Modulators for Kidney Protection in Nondiabetic Kidney Disease. 胰高血糖素样肽-1受体激动剂和多激素受体调节剂在非糖尿病肾病中的肾保护作用。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-19 DOI: 10.1681/ASN.0000001306
Sachin V Pasricha, Labib I Faruque, Mai Mohsen, Tyler D Brown, Kevin Yau, Kyle D Medak, David Z I Cherney, Marcel H A Muskiet, Ayodele Odutayo
{"title":"Glucagon-Like Peptide-1 Receptor Agonists and Multi-hormone Receptor Modulators for Kidney Protection in Nondiabetic Kidney Disease.","authors":"Sachin V Pasricha, Labib I Faruque, Mai Mohsen, Tyler D Brown, Kevin Yau, Kyle D Medak, David Z I Cherney, Marcel H A Muskiet, Ayodele Odutayo","doi":"10.1681/ASN.0000001306","DOIUrl":"https://doi.org/10.1681/ASN.0000001306","url":null,"abstract":"<p><p>Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), together with newer multi-hormone receptor modulators that target glucose-dependent insulinotropic polypeptide (GIP), glucagon and amylin, have emerged as promising therapies for chronic kidney disease. This review examines the mechanisms through which these agents may protect the kidney and summarizes the emerging clinical evidence in populations without diabetes. Kidney protection appears to arise through complementary direct and indirect routes. Direct effects include natriuresis through inhibition of the sodium-hydrogen exchanger (NHE)-3, modulation of glomerular hemodynamics through effects on afferent arteriolar tone and vasoconstrictor pathways, and attenuation of renal inflammation; mechanisms that are largely independent of glucose lowering. Indirect mechanisms include reductions in the metabolic, hemodynamic and cardiac burden on the kidney through weight loss, blood pressure lowering, and improvement of heart failure. Beyond selective GLP-1R-agonism, the added hormonal components of multi-hormone receptor modulators engage distinct physiological pathways whose interactions may be additive, synergistic or counteracting, but remain incompletely understood. The efficacy of GLP-1 RAs and multi-hormone receptor modulators in people without diabetes is currently supported by results from secondary kidney endpoints in phase-3 obesity and cardiovascular outcome trials, including reductions in albuminuria and preservation of estimated glomerular filtration rate. Several dedicated outcome studies of GLP-1 RAs and multi-hormone receptor modulators are now underway and will determine whether these therapies become a new pillar of care in nondiabetic kidney disease.</p>","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Authors' Reply: Carry Life UF System: Potential and Risks of Steady Concentration Peritoneal Dialysis. 作者回复：携带生命UF系统：稳定浓度腹膜透析的潜力和风险。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-15 DOI: 10.1681/ASN.0000001261
Martin Wilkie, Olof Heimbürger, Charlotte de Leon, Jörgen Hegbrant
{"title":"Authors' Reply: Carry Life UF System: Potential and Risks of Steady Concentration Peritoneal Dialysis.","authors":"Martin Wilkie, Olof Heimbürger, Charlotte de Leon, Jörgen Hegbrant","doi":"10.1681/ASN.0000001261","DOIUrl":"https://doi.org/10.1681/ASN.0000001261","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carry Life UF System: Potential and Risks of Steady Concentration Peritoneal Dialysis. 携带生命UF系统：稳定浓度腹膜透析的潜力和风险。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-15 DOI: 10.1681/ASN.0000001260
Ettore Pasquinucci, Fabio Rosario Salerno, Margherita Scola, Vincenzo La Milia
{"title":"Carry Life UF System: Potential and Risks of Steady Concentration Peritoneal Dialysis.","authors":"Ettore Pasquinucci, Fabio Rosario Salerno, Margherita Scola, Vincenzo La Milia","doi":"10.1681/ASN.0000001260","DOIUrl":"https://doi.org/10.1681/ASN.0000001260","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kidney Protection from Glucagon-Like Peptide-1 Receptor Agonists: Simply a Result of Weight Loss, or Something Else? 胰高血糖素样肽-1受体激动剂对肾脏的保护作用：仅仅是减肥的结果，还是其他原因？
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-14 DOI: 10.1681/ASN.0000001303
Allon N Friedman, Gavin Hale
{"title":"Kidney Protection from Glucagon-Like Peptide-1 Receptor Agonists: Simply a Result of Weight Loss, or Something Else?","authors":"Allon N Friedman, Gavin Hale","doi":"10.1681/ASN.0000001303","DOIUrl":"https://doi.org/10.1681/ASN.0000001303","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
β-Blockers in Hemodialysis Outcome Trial. β受体阻滞剂在血液透析结局试验中的应用。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-12 DOI: 10.1681/ASN.0000001264
Areef Ishani, Christopher Donnelly, Srihari Raju, Sarah Leatherman
{"title":"β-Blockers in Hemodialysis Outcome Trial.","authors":"Areef Ishani, Christopher Donnelly, Srihari Raju, Sarah Leatherman","doi":"10.1681/ASN.0000001264","DOIUrl":"https://doi.org/10.1681/ASN.0000001264","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Alzheimer's Disease Cerebrospinal Fluid Biomarkers in CKD: A Caution for Clinicians. 在CKD中使用阿尔茨海默病脑脊液生物标志物：对临床医生的警告。
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-12 DOI: 10.1681/ASN.0000001256
Aditi Gupta
{"title":"Using Alzheimer's Disease Cerebrospinal Fluid Biomarkers in CKD: A Caution for Clinicians.","authors":"Aditi Gupta","doi":"10.1681/ASN.0000001256","DOIUrl":"https://doi.org/10.1681/ASN.0000001256","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microvascular Inflammation in Kidney Transplants: More Heterogeneous Than We Thought? 肾移植中的微血管炎症：比我们想象的更异质性？
IF 9.7 1区 医学
Journal of The American Society of Nephrology Pub Date : 2026-10-12 DOI: 10.1681/ASN.0000001275
Alexandre Loupy, Michael Mengel
{"title":"Microvascular Inflammation in Kidney Transplants: More Heterogeneous Than We Thought?","authors":"Alexandre Loupy, Michael Mengel","doi":"10.1681/ASN.0000001275","DOIUrl":"https://doi.org/10.1681/ASN.0000001275","url":null,"abstract":"","PeriodicalId":17217,"journal":{"name":"Journal of The American Society of Nephrology","volume":" ","pages":""},"PeriodicalIF":9.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书