Journal of the American Dental Association最新文献

{"title":"Cartridge-based flavored water bottles may pose a risk of developing dental erosion","authors":"Marlus da Silva Pedrosa DDS, PhD, Clementina Astorga, Leonardo Luca Iannaccone, Apoena Aguiar Ribeiro DDS, MSc, PhD","doi":"10.1016/j.adaj.2025.12.004","DOIUrl":"10.1016/j.adaj.2025.12.004","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1077-1080"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toothpaste-induced contact stomatitis","authors":"Eleni-Marina Kalogirou DDS, MSc, PhD,&nbsp;Marianna Vasilaki BSc,&nbsp;Georgios Charalampakis DDS, MSc, PhD,&nbsp;Theodora Theodosopoulou BSc, MPharm, MSc,&nbsp;Konstantinos I. Tosios DDS, PhD","doi":"10.1016/j.adaj.2026.03.004","DOIUrl":"10.1016/j.adaj.2026.03.004","url":null,"abstract":"<div><h3>Background</h3><div>Toothpaste-induced contact stomatitis (TICS) has mainly been reported as single case reports or short case series. The authors’ objective in this study was to report 56 cases of TICS and to perform a scoping literature review.</div></div><div><h3>Methods</h3><div>The records of TICS cases diagnosed from 2022 through 2025 were retrieved from 2 private oral medicine practices, and data regarding demographic characteristics, clinical characteristics, symptoms, toothpaste brand and type used, and management were summarized. The literature was searched via PubMed or MEDLINE, Web of Science, and Embase (Ovid) for TICS cases with available toothpaste brand name and photographic documentation.</div></div><div><h3>Results</h3><div>Forty-one females and 15 males received a diagnosis of TICS manifesting as white desquamative lesions (35/56), erythema (30/56), and pinpoint hemorrhage (20/56) that mainly affected ventral tongue or floor of the mouth (33/56), lower labial mucosa (23/56), and anterior maxillary gingiva (18/56). Most patients (54/56) were symptomatic, reporting pain or irritation, burning, swelling, and discomfort during tongue movement or toothbrushing. All toothpastes used included flavors, hydrated silica, and sodium saccharin as well as cocamidopropyl betaine or sodium lauryl sulfate. Complete resolution was observed at 1 through 2 weeks after substituting the toothpaste in all cases. The literature review yielded 25 studies including 70 relevant cases.</div></div><div><h3>Conclusions</h3><div>White desquamative lesions, erythema, or pinpoint hemorrhage on ventral tongue or floor of the mouth, labial mucosa, or anterior gingiva in patients mentioning discomfort during toothbrushing would be suggestive of TICS, which is a clinical diagnosis made on the basis of response to substitution of the suspected agent.</div></div><div><h3>Practical Implications</h3><div>The authors provide a comprehensive overview of clinical manifestations and toothpastes that might be associated with TICS, which may enhance diagnostic awareness among the dental community.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1187-1201.e9"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147948630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral assessment of patients with X-linked hypophosphatemic rickets","authors":"Jaqueline Buzato DDS,&nbsp;Victor Luiz De Castro Santos MSc,&nbsp;Maria Carolina Botelho Pires de Campos MSc,&nbsp;Mariana Perotta PhD,&nbsp;Cintia Mussi Milani PhD,&nbsp;Natanael Henrique Mattos PhD,&nbsp;Carolina Aguiar Moreira PhD,&nbsp;Giordano Oliveira Zandoná MSc,&nbsp;Camila Paiva Perin PhD,&nbsp;Liliane Roskamp PhD","doi":"10.1016/j.adaj.2026.03.002","DOIUrl":"10.1016/j.adaj.2026.03.002","url":null,"abstract":"<div><h3>Background</h3><div>X-linked hypophosphatemic rickets (XLH) is a hereditary disorder caused by <em>PHEX</em> sequence variations, leading to excess fibroblast growth factor 23, chronic hypophosphatemia, and impaired mineralization of skeletal and dental tissues. Patients frequently have spontaneous periapical abscesses, taurodontism, periodontal disease, and delayed tooth eruption.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, the authors evaluated the oral health of 17 participants aged 4 through 61 years with clinically and genetically confirmed XLH. Standardized clinical examinations and radiographic assessments documented dental findings, periodontal status, and decayed, missing, and filled teeth index scores (calculated as the sum of decayed, missing, and filled permanent teeth).</div></div><div><h3>Results</h3><div>Spontaneous dental abscesses were reported in 12 participants (70.6%). Periodontitis was diagnosed in 10 participants (77%), taurodontism was diagnosed in 5 participants (29%), and root fusion was diagnosed in 2 participants (18%). Adults had at least 1 tooth with enlarged pulp chambers, prominent pulp horns, thin enamel and dentin, or open apexes. The mean decayed, missing, and filled teeth index score among adults was 14, exceeding the national mean in Brazil.</div></div><div><h3>Conclusions</h3><div>Patients with XLH exhibit a high prevalence of dental complications, particularly spontaneous abscesses and periodontal disease. These findings underscore the importance of early diagnosis and continuous follow-up to effectively monitor and preserve oral health.</div></div><div><h3>Practical Implications</h3><div>Patients with XLH often develop spontaneous dental abscesses and periodontal disease, even in teeth without caries or trauma. Early recognition of radiographic features such as enlarged pulp chambers, taurodontism, open apexes, and thin dentin helps clinicians avoid misdiagnosis and unnecessary treatments. Dentists should implement tailored preventive strategies and schedule frequent monitoring to reduce complications and prevent early tooth loss.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1127-1134"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When simplicity sells","authors":"Mohammed Turky MSc, PhD","doi":"10.1016/j.adaj.2026.07.015","DOIUrl":"10.1016/j.adaj.2026.07.015","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1234-1235"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors’ Response","authors":"W. Benton Swanson DDS, PhD,&nbsp;David T. Wu DMD, DMSc,&nbsp;Mutsumi Yoshida PhD,&nbsp;Jeanne Ambruster BA,&nbsp;Charles S. Sfeir DDS, PhD,&nbsp;William R. Wagner PhD,&nbsp;David J. Mooney PhD,&nbsp;William V. Giannobile DDS, DMSc,&nbsp;David H. Kohn PhD","doi":"10.1016/j.adaj.2026.08.004","DOIUrl":"10.1016/j.adaj.2026.08.004","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1089-1090"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving perinatal oral health care access","authors":"Sarah Cook DDS, MPH,&nbsp;Rocio B. Quinonez DMD, MS, MPH,&nbsp;Martha Ann Keels DDS, PhD,&nbsp;Paul Mihas MA,&nbsp;Zachary A. Brian DMD, MHA","doi":"10.1016/j.adaj.2026.03.005","DOIUrl":"10.1016/j.adaj.2026.03.005","url":null,"abstract":"<div><h3>Background</h3><div>Oral health during the perinatal period is correlated to health of mother and child. In 2022, North Carolina (NC) legislators revised Medicaid for Pregnant Women (MPW) policies to expand oral health care coverage up to 12 months postpartum. However, usage of benefits remains low across the state. The authors sought to address low usage by means of identifying consumer-centered system-level strategies.</div></div><div><h3>Methods</h3><div>Using qualitative methodology, one-on-one interviews were held with 14 MPW beneficiaries selected by means of convenience sample and recruited in rural and urban NC counties. Participant transcripts were systematically analyzed for themes using MAXQDA software, Version 2022 (VERBI Software). Interviews continued until data saturation was achieved, indicating sufficient information power.</div></div><div><h3>Results</h3><div>Three of 14 participants knew about their MPW oral health care coverage. Themes identified were grouped into 2 categories: barriers to usage and suggestions to improve usage. Barriers included access challenges (8/14), time constraints and lack of prioritization of oral health care (7/14), and economic challenges (6/14). Suggestions included improved education (14/14), access to care interventions (11/14), financial support (10/14), and emotional support services (5/14).</div></div><div><h3>Conclusions</h3><div>On the basis of the themes in participant responses, the authors recommend enhancement of informational resources provided by means of NC Medicaid to MPW beneficiaries, increasing funding for Medicaid caseworkers to aid MPW beneficiaries in accessing care, improving education on oral health care and MPW oral health care benefits for prenatal health care providers, and increasing accessibility of Medicaid providers. Future researchers should investigate oral and prenatal health care provider attitudes and perspectives.</div></div><div><h3>Practical Implications</h3><div>The authors propose real-world implementation of these recommendations and suggest specific action steps to do so.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1151-1161.e23"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unpacking X (formerly Twitter) discourse on fluoride and related topics during the 2024 US presidential election","authors":"Owen Visser MS,&nbsp;Naman Singhal BTech, MS,&nbsp;Mohit Katta MS,&nbsp;Eugene Pinsky PhD,&nbsp;Somnath Datta PhD,&nbsp;Astha Singhal BDS, MPH, PhD","doi":"10.1016/j.adaj.2026.03.007","DOIUrl":"10.1016/j.adaj.2026.03.007","url":null,"abstract":"<div><h3>Background</h3><div>Fluoride is a cornerstone of caries prevention, yet public trust in fluoride has become increasingly contested, particularly on social media platforms where health misinformation and political narratives intersect. Understanding how fluoride is discussed online may inform strategies to improve communication and public confidence in oral health interventions.</div></div><div><h3>Methods</h3><div>The authors analyzed publicly available posts from X (formerly Twitter) (X Corp) during the 2024 US presidential election that referenced fluoride and related topics. Natural language processing techniques were used to classify post sentiment and emotional tone and to identify dominant discussion themes. Comparisons were made between fluoride-related posts and general posts by the same users to assess differences in sentiment distribution and emotional expression.</div></div><div><h3>Results</h3><div>Fluoride-related discourse was considerably more negative than general discourse on the platform. Negative sentiment toward fluoride was frequently associated with distrust in government and public health institutions, political polarization, and perceived health risks. Positive discourse emphasized caries prevention, dental products, and evidence-based public health benefits. Users expressing negative sentiments toward fluoride were also more likely to express negative sentiments in non–fluoride-related posts.</div></div><div><h3>Conclusions</h3><div>Online discussions about fluoride during a politically charged period reflected broader sociopolitical beliefs and emotional responses rather than isolated concerns about dental science.</div></div><div><h3>Practical Implications</h3><div>Dental care professionals should recognize that patient concerns about fluoride may stem from emotionally driven narratives encountered online. Communication strategies that acknowledge concerns while clearly explaining the safety and benefits of fluoride may support effective patient counseling and public engagement.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1118-1126.e7"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protecting patients beyond the chair","authors":"Thomas M. Paumier DDS","doi":"10.1016/j.adaj.2026.08.009","DOIUrl":"10.1016/j.adaj.2026.08.009","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1073-1076"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart peptide–based materials and their clinical application for caries management","authors":"Yipeng Fu BDS, MDS, PhD,&nbsp;Richard D. Cannon MA, PhD,&nbsp;Lei Cheng BDS, MDS, PhD,&nbsp;Kai Chun Li PhD,&nbsp;Manikandan Ekambaram BDS, MDS, PhD,&nbsp;Paul R. Cooper PhD,&nbsp;May L. Mei BDS, MDS, PhD","doi":"10.1016/j.adaj.2026.07.002","DOIUrl":"10.1016/j.adaj.2026.07.002","url":null,"abstract":"<div><h3>Background</h3><div>Caries remains the most prevalent biofilm-mediated disease, requiring a shift toward minimally invasive, biologically driven management. Conventional therapies lack specificity and may disrupt microbial balance. Smart peptide–based materials provide a precision-guided strategy enabling the simultaneous targeting of cariogenic pathogens and promotion of biomimetic remineralization.</div></div><div><h3>Types of Studies Reviewed</h3><div>The authors examined the literature regarding the design principles, mechanisms of action, and translational potential of smart peptide–based anticaries systems, including antimicrobial, remineralizing, and environmentally responsive constructs, and clinical use in caries management.</div></div><div><h3>Results</h3><div>Smart peptides are engineered to sense disease-associated cues such as acidic pH, specific cariogenic bacteria, or tooth-binding ability. Targeted antimicrobial peptides selectively inhibit cariogenic pathogens while preserving commensal microbiota. Remineralizing peptides guide biomimetic mineralization in early lesions. Multifunctional constructs that integrate these properties address both microbial dysbiosis and tissue demineralization. Although most systems remain preclinical, emerging in vivo and early clinical evidence support their feasibility and translational potential.</div></div><div><h3>Conclusions and Practical Implications</h3><div>Smart peptide–based materials provide a precision-guided and minimally invasive approach for caries management. By means of integrating pathogen-targeted antimicrobial activity with biomimetic tissue repair and environmental responsiveness, these materials align closely with the principles of precision dentistry. Continued development and clinical validation may enable personalized, microbiome-sparing, and lesion-specific interventions in routine oral health care.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Pages 1105-1117"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental-Medical Terminology","authors":"Steven A. Saxe DMD,&nbsp;Daniel L. Orr II DDS, MS (Anesth), PhD, JD, MD","doi":"10.1016/j.adaj.2026.07.032","DOIUrl":"10.1016/j.adaj.2026.07.032","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"157 10","pages":"Page 1086"},"PeriodicalIF":4.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}