Yufeng Wu , Yunrui Lu , Shiyu Zhu , Meixiang Xiang , Yao Xie
{"title":"AS-1005 The Prognosis of General Population With Left Bundle Branch Block: A Systematic Review and Meta-Analysis","authors":"Yufeng Wu , Yunrui Lu , Shiyu Zhu , Meixiang Xiang , Yao Xie","doi":"10.1016/j.jacc.2024.10.034","DOIUrl":"10.1016/j.jacc.2024.10.034","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Page C11"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shahnawaz Amdani MD , James K. Kirklin MD , Ryan Cantor PhD , Devin Koehl MSDS , Ashwin Lal MD , Peter Chau MD , Valerie Curren MBBCh , Jonathan B. Edelson MD , John J. Parent MD , Hannah Victor MSN, CNP , Ali Burnette MSN, FNP , Jacqueline M. Lamour MD
{"title":"Prevalence and Impact of Recurrent Rejection on Pediatric Heart Transplant Recipients","authors":"Shahnawaz Amdani MD , James K. Kirklin MD , Ryan Cantor PhD , Devin Koehl MSDS , Ashwin Lal MD , Peter Chau MD , Valerie Curren MBBCh , Jonathan B. Edelson MD , John J. Parent MD , Hannah Victor MSN, CNP , Ali Burnette MSN, FNP , Jacqueline M. Lamour MD","doi":"10.1016/j.jacc.2024.08.010","DOIUrl":"10.1016/j.jacc.2024.08.010","url":null,"abstract":"<div><h3>Background</h3><div>Studies evaluating the prevalence and impact of recurrent rejection (RR) in pediatric heart transplant (HT) are sparse.</div></div><div><h3>Objectives</h3><div>The purpose of this study was to describe prevalence and impact of RR on cardiac allograft vasculopathy (CAV) and graft loss after pediatric HT.</div></div><div><h3>Methods</h3><div>Data on HT from January 1, 2000, to June 30, 2020, in the Pediatric Heart Transplant Society database were included. Freedom from RR (≥2 rejection episodes) was compared by era (early: 2000-2009; current: 2010-2020). Outcomes for children experiencing RR were compared with those experiencing 0 or 1 rejection episodes and by type of RR (antibody-mediated rejection [AMR], acute cellular rejection [ACR], mixed [ACR/AMR]).</div></div><div><h3>Results</h3><div>Of 6,342 HT recipients, 1,035 (17%) experienced RR. In the current era, pediatric HT recipients were less likely to experience RR (<em>P <</em> 0.001). Freedom from CAV was similar for those experiencing RR to those experiencing 0 or 1 episode (96.6% vs 95.3% vs 96.6%); and similar regardless of the type of RR (AMR, ACR, or mixed) (65.5% vs 82.9% vs 100%) (<em>P ></em> 0.05). Freedom from graft loss was significantly lower for those experiencing RR to those experiencing 0 or 1 episode (56.3% vs 72.3% vs 82.3%) and lower for those experiencing recurrent mixed rejection or recurrent AMR compared with those experiencing recurrent ACR (65.3% vs 50% vs 81.8%). Black children experiencing RR subsequently had lower freedom from CAV and graft loss than White children (<em>P <</em> 0.05 for all).</div></div><div><h3>Conclusions</h3><div>Although prevalence of RR has decreased, children experiencing RR are at greatly increased risk for losing their graft, particularly those who have recurrent mixed or antibody-mediated rejection.</div></div>","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages 2170-2182"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142369535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaimie Coburn MBBCh, Pieter A. Neef MD, Simon Hobson MBChB, Jonathan R. Dalzell MD
{"title":"Clinical Signs of Congestion in Younger Patients With Decompensated Heart Failure","authors":"Jaimie Coburn MBBCh, Pieter A. Neef MD, Simon Hobson MBChB, Jonathan R. Dalzell MD","doi":"10.1016/j.jacc.2024.08.079","DOIUrl":"10.1016/j.jacc.2024.08.079","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Page e323"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zeya Li , Yu Zhao , Weihua Chen , Dongjie Du , Xianzhong Gu , Rongchong Huang
{"title":"AS-0031 Mildly Decreased eGFR Modifies the Association Between Uric Acid and Risk of Kidney Function Decline: a 5-Year Population-Based Cohort Study","authors":"Zeya Li , Yu Zhao , Weihua Chen , Dongjie Du , Xianzhong Gu , Rongchong Huang","doi":"10.1016/j.jacc.2024.10.062","DOIUrl":"10.1016/j.jacc.2024.10.062","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages C21-C22"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daoyao Fu , Mengxuan Xiao , Yuan Sui , Wenjun Xiong
{"title":"AS-0076 Overexpression of USP2 Regulates MFN2 Deubiquitination Through the USP2/MFN2 Axis to Alleviate Mitochondrial Dysfunction and Myocardial Hypertrophy Induced by Angiotensin II–Induced Calcium Overload","authors":"Daoyao Fu , Mengxuan Xiao , Yuan Sui , Wenjun Xiong","doi":"10.1016/j.jacc.2024.10.007","DOIUrl":"10.1016/j.jacc.2024.10.007","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Page C2"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ze Zhang , Lei Zhu , Su-Tao Hu , Yu-Kun Zhang , Tian-Shu Gu , Chao Jiang , Jing-Kun Zhang , Xue Wu , Xing Liu , Tong Liu , Kang-Yin Chen
{"title":"AS-0248 Favorable Short-Term Clinical Outcomes in Patients With Type 2 Myocardial Infarction Complicated With Acute Respiratory Failure","authors":"Ze Zhang , Lei Zhu , Su-Tao Hu , Yu-Kun Zhang , Tian-Shu Gu , Chao Jiang , Jing-Kun Zhang , Xue Wu , Xing Liu , Tong Liu , Kang-Yin Chen","doi":"10.1016/j.jacc.2024.10.056","DOIUrl":"10.1016/j.jacc.2024.10.056","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages C19-C20"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Song Wen , Zehan Huang , Yuqing Huang , Feng Wang , Dunliang Ma , Feihuang Han , Qiheng Wan , Bin Zhang
{"title":"AS-0215 Predictors of Retrograde Percutaneous Coronary Intervention Success for Chronic Total Occlusion","authors":"Song Wen , Zehan Huang , Yuqing Huang , Feng Wang , Dunliang Ma , Feihuang Han , Qiheng Wan , Bin Zhang","doi":"10.1016/j.jacc.2024.10.040","DOIUrl":"10.1016/j.jacc.2024.10.040","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages C13-C14"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AS-0274 Precision Treatment of Complex Aortic Arch Lesions Using 3D Printing-based DISF Technique","authors":"Cheng Wei , Yu Sanjiu","doi":"10.1016/j.jacc.2024.10.052","DOIUrl":"10.1016/j.jacc.2024.10.052","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages C17-C18"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendon L. Neuen PhD , John W. Ostrominski MD , Brian Claggett PhD , Iris E. Beldhuis MD , Safia Chatur MD , Finnian R. McCausland MBBCh , Sunil V. Badve PhD , Clare Arnott PhD , Hiddo J.L. Heerspink PhD , Min Jun PhD , Michael Falster PhD , Juliana de Oliveira Costa PhD , Carol Pollock PhD , Meg J. Jardine PhD , Kenneth W. Mahaffey MD , Vlado Perkovic PhD , Scott D. Solomon MD , Muthiah Vaduganathan MD, MPH
{"title":"Bidirectional Relationship Between Kidney Disease Progression and Cardiovascular Events in Type 2 Diabetes","authors":"Brendon L. Neuen PhD , John W. Ostrominski MD , Brian Claggett PhD , Iris E. Beldhuis MD , Safia Chatur MD , Finnian R. McCausland MBBCh , Sunil V. Badve PhD , Clare Arnott PhD , Hiddo J.L. Heerspink PhD , Min Jun PhD , Michael Falster PhD , Juliana de Oliveira Costa PhD , Carol Pollock PhD , Meg J. Jardine PhD , Kenneth W. Mahaffey MD , Vlado Perkovic PhD , Scott D. Solomon MD , Muthiah Vaduganathan MD, MPH","doi":"10.1016/j.jacc.2024.08.006","DOIUrl":"10.1016/j.jacc.2024.08.006","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"84 22","pages":"Pages 2246-2250"},"PeriodicalIF":21.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}