Martha Gulati, Mykela M Moore, Morgane Cibotti-Sun
{"title":"2025 High Blood Pressure Guideline-at-a-Glance.","authors":"Martha Gulati, Mykela M Moore, Morgane Cibotti-Sun","doi":"10.1016/j.jacc.2025.07.010","DOIUrl":"10.1016/j.jacc.2025.07.010","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Aldosteronism: Ubiquitous, Yet Unrecognized.","authors":"Jenifer M Brown, Anand Vaidya","doi":"10.1016/j.jacc.2025.08.014","DOIUrl":"10.1016/j.jacc.2025.08.014","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Why Can't We Get There?: Understanding Persistent Hypertension in Real-World Care.","authors":"Yuan Lu","doi":"10.1016/j.jacc.2025.08.009","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.08.009","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treat the Weight, Lower the Pressure: Glucagon-Like Peptide-1-Based Therapies and Blood Pressure.","authors":"Naveed Sattar, Christian Delles","doi":"10.1016/j.jacc.2025.07.059","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.07.059","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen E Joynt Maddox, Ezekiel J Emanuel, Robert A Berenson
{"title":"Policy Agenda to Close the Hypertension Gap.","authors":"Karen E Joynt Maddox, Ezekiel J Emanuel, Robert A Berenson","doi":"10.1016/j.jacc.2025.08.011","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.08.011","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The DASH Diet in 2025: Still Foundational, Still Underused.","authors":"Christina Filippou","doi":"10.1016/j.jacc.2025.08.010","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.08.010","url":null,"abstract":"","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel W Jones, Keith C Ferdinand, Sandra J Taler, Heather M Johnson, Daichi Shimbo, Marwah Abdalla, M Martine Altieri, Nisha Bansal, Natalie A Bello, Adam P Bress, Jocelyn Carter, Jordana B Cohen, Karen J Collins, Yvonne Commodore-Mensah, Leslie L Davis, Brent Egan, Sadiya S Khan, Donald M Lloyd-Jones, Bernadette Mazurek Melnyk, Eva A Mistry, Modele O Ogunniyi, Stacey L Schott, Sidney C Smith, Amy W Talbot, Wanpen Vongpatanasin, Karol E Watson, Paul K Whelton, Jeff D Williamson
{"title":"2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.","authors":"Daniel W Jones, Keith C Ferdinand, Sandra J Taler, Heather M Johnson, Daichi Shimbo, Marwah Abdalla, M Martine Altieri, Nisha Bansal, Natalie A Bello, Adam P Bress, Jocelyn Carter, Jordana B Cohen, Karen J Collins, Yvonne Commodore-Mensah, Leslie L Davis, Brent Egan, Sadiya S Khan, Donald M Lloyd-Jones, Bernadette Mazurek Melnyk, Eva A Mistry, Modele O Ogunniyi, Stacey L Schott, Sidney C Smith, Amy W Talbot, Wanpen Vongpatanasin, Karol E Watson, Paul K Whelton, Jeff D Williamson","doi":"10.1016/j.jacc.2025.05.007","DOIUrl":"10.1016/j.jacc.2025.05.007","url":null,"abstract":"<p><strong>Aim: </strong>The \"2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults\" retires and replaces the \"2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults.\"</p><p><strong>Methods: </strong>A comprehensive literature search was conducted from December 2023 to June 2024 to identify clinical studies, reviews, and other evidence performed on human subjects that were published since February 2015 in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline.</p><p><strong>Structure: </strong>The focus of this clinical practice guideline is to create a living, working document updating current knowledge in the field of high blood pressure aimed at all practicing primary care and specialty clinicians who manage patients with hypertension.</p>","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":" ","pages":""},"PeriodicalIF":22.3,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of HEPA Filtration Air Purifiers on Blood Pressure: A Pragmatic Randomized Crossover Trial","authors":"Doug Brugge, Misha Eliasziw, Mohan Thanikachalam, Vedaant Kuchhal, Chermaine Morson, Teresa Vazquez-Dodero, Amy Mertl, Pratham Tallam, Sangita Kunwar, Linda Sprague Martinez, Humza Shamoon Rashid, Kiran Singh-Smith, Hunter Gates, Sharly Palma, Warren Goldstein-Gelb, Shir Lerman Ginzburg, Scott Oakley Hersey, Francesca Majluf, Wig Zamore","doi":"10.1016/j.jacc.2025.06.037","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.06.037","url":null,"abstract":"<h3>Background</h3>Particulate matter (PM) pollution is a leading cause of cardiovascular risk and illness, including elevated blood pressure (BP).<h3>Objectives</h3>The purpose of this study was to test the efficacy of in-home air purifiers to reduce BP for adults living adjacent to highways.<h3>Methods</h3>We conducted a pragmatic randomized crossover trial of the effect of high-efficiency particulate arrestance (HEPA) vs sham filtration on BP. Residences were randomized to start with 1 month of HEPA filtration or 1 month of sham filtration. A 1-month wash out period with no filtration was followed by 1 month of the alternate filtration. Participant questionnaire data and BP were collected 4 times, at the start and end of each filtration period. PM concentrations were measured in a subset of residences. Linear mixed models were used to compare the mean change in BP between the HEPA and sham filtration periods. Models were adjusted for time invariant and time-varying covariates.<h3>Results</h3>A total of 154 participants were analyzed. The mean age was 41.1 years, 59.7% were women, 68.2% were non-Hispanic White, and a majority were of higher socioeconomic status. The mean baseline brachial systolic blood pressure (SBP)/diastolic BP was 118.8/76.5 mm Hg. HEPA filtration significantly reduced PM in comparison to both indoor sham and outdoor levels. Participants’ SBP at the start of the intervention period moderated the efficacy of the intervention <em>(P =</em> 0.03). Participants who had elevated brachial SBP (≥120 mm Hg) had a significant 2.8-mm Hg mean reduction in SBP after HEPA filtration <em>(P =</em> 0.03) and a 0.2-mm Hg mean increase in SBP after sham filtration <em>(P =</em> 0.85). The net result was a significant 3.0-mm Hg mean difference in favor of HEPA filtration <em>(P =</em> 0.04). There was no significant benefit on diastolic BP or for participants with normal SBP (<120 mm Hg).<h3>Conclusions</h3>The use of in-home HEPA air purifiers resulted in clinically important reductions in SBP for people with elevated SBP in environments with relatively low PM<sub>2.5</sub> concentrations.","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"1 1","pages":""},"PeriodicalIF":24.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tom Kai Ming Wang, Allan L. Klein, Paul C. Cremer, Massimo Imazio, Sarah Kohnstamm, Sushil Allen Luis, Vartan Mardigyan, Monica Mukherjee, Karen Ordovas, Sneha Vakamudi, George F. Wohlford
{"title":"2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on the Diagnosis and Management of Pericarditis: A Report of the American College of Cardiology Solution Set Oversight Committee","authors":"Tom Kai Ming Wang, Allan L. Klein, Paul C. Cremer, Massimo Imazio, Sarah Kohnstamm, Sushil Allen Luis, Vartan Mardigyan, Monica Mukherjee, Karen Ordovas, Sneha Vakamudi, George F. Wohlford","doi":"10.1016/j.jacc.2025.05.023","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.05.023","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Solution Set Oversight Committee</h2>Gurusher S. Panjrath, MBBS, FACC, <em>Chair</em>Nicole M. Bhave, MD, FACC, <em>Immediate Past Chair</em><em><sup>∗</sup></em>Niti R. Aggarwal, MD, FACC<em><sup>∗</sup></em>Katie Bates, ARNP, DNPEugene Chung, MD, MPH, FACCDavid M. Dudzinski, MD, JD, FACCJohn P. Erwin III, MD, FACC<em><sup>∗</sup></em>Martha Gulati, MD, MS, FACCRobert Hendel, MD, MACCDharam J. Kumbhani, MD, SM, FACC<em><sup>∗</sup></em>Chayakrit Krittanawong, MD, FACCBarbara Wiggins, PharmD, FACCMegan Coylewright, MD, MPH, FACC—<em>Ex Officio</em></section></section><section><section><h2>Table of Contents</h2><ul><li><span></span><span>Preface<!-- --> <!-- -->2</span></li><li><span>1.</span><span>Introduction<!-- --> <!-- -->3</span></li><li><span>2.</span><span>Assumptions and Definitions<!-- --> <!-- -->3<ul><li><span>2.1.</span><span>General Clinical Assumptions<!-- --> <!-- -->3</span></li><li><span>2.2.</span><span>Definitions<!-- --> <!-- -->3</span></li><li><span>2.3.</span><span>Abbreviations<!-- --> <!-- -->3</span></li></ul></span></li><li><span>3.</span><span>Summary Graphic<!-- --> <!-- -->4<ul><li><span></span><span>Figure 1. Novel Clinical and Advanced Multimodality Imaging Evaluation Guiding Therapeutics for Pericarditis<!-- --> <!-- -->4</span></li></ul></span></li><li><span>4.</span><span>Description, Rationale, and Implications<!-- --> <!-- -->4<ul><li><span>4.1.</span><span>General Perspectives for Pericardial Diseases<!-- --> <!-- -->4<ul><li><span>4.1.1.</span><span>Anatomy and Physiology<!-- --> <!-- -->4<ul><li><span></span><span>Figure 2. Anatomy of the Pericardium<!-- --> <!-- -->5</span></li></ul></span></li><li><span>4.1.2.</span><span>Epidemiology and Etiologies<!-- --> <!-- -->6</span></li><li><span>4.1.3.</span><span>The Role of Inflammation in Pericardial Disease<!-- --> <!-- -->6<ul><li><span></span><span>Figure 3. Pathophysiology of Pericardial</span></li></ul></span></li></ul></span></li></ul></span></li></ul></section></section><section><section><h2>Preface</h2>The American College of Cardiology (ACC) has a long history of developing documents (eg, decision pathways, appropriate use criteria) to provide clinicians with guidance on both clinical and nonclinical topics relevant to cardiovascular care. In most circumstances, these documents have been created to complement clinical practice guidelines and to inform clinicians about areas where evidence is new and evolving or where sufficient data is more limited. Despite this, numerous gaps persist,</section></section><section><section><section><h2>General Clinical Assumptions</h2><ul><li><span>1.</span><span>This CCG presumes the physician will collaborate with appropriate specialists, such as a cardiologist, pharmacist, and/or other relevant specialists (eg, rheumatologist, cardiac surgeon, radiologist), and/or pericardial center of excellence program members, including advanced practice providers, to guide clinical ","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"31 1","pages":""},"PeriodicalIF":24.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan D. Newman, Sanjay Rajagopalan, Robert D. Brook
{"title":"Breathing Easier: Air Filtration to Improve Indoor Air Quality as a Cardiovascular Intervention","authors":"Jonathan D. Newman, Sanjay Rajagopalan, Robert D. Brook","doi":"10.1016/j.jacc.2025.06.038","DOIUrl":"https://doi.org/10.1016/j.jacc.2025.06.038","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Funding Support and Author Disclosures</h2>Dr Newman has received funding from National Institutes of Health relevant to this paper. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.</section></section>","PeriodicalId":17187,"journal":{"name":"Journal of the American College of Cardiology","volume":"27 1","pages":""},"PeriodicalIF":24.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}