Journal of Skin Cancer最新文献

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Decrease in Self-Reported Tanning Frequency among Utah Teens following the Passage of Utah Senate Bill 41: An Analysis of the Effects of Youth-Access Restriction Laws on Tanning Behaviors. 犹他州参议院第41号法案通过后,犹他州青少年自我报告的晒黑频率下降:青少年访问限制法律对晒黑行为的影响分析。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-08-20 DOI: 10.1155/2014/839601
Rebecca G Simmons, Kristi Smith, Meghan Balough, Michael Friedrichs
{"title":"Decrease in Self-Reported Tanning Frequency among Utah Teens following the Passage of Utah Senate Bill 41: An Analysis of the Effects of Youth-Access Restriction Laws on Tanning Behaviors.","authors":"Rebecca G Simmons,&nbsp;Kristi Smith,&nbsp;Meghan Balough,&nbsp;Michael Friedrichs","doi":"10.1155/2014/839601","DOIUrl":"https://doi.org/10.1155/2014/839601","url":null,"abstract":"<p><p>Introduction. Adolescent use of indoor tanning facilities is associated with an increased risk in later development of melanoma skin cancers. States that have imposed age restrictions on access to indoor tanning generally show lower self-reported rates of indoor tanning than states with no restrictions, but currently no studies have assessed indoor tanning use before and after such restrictions. Methods. In 2013, we compared self-reported indoor tanning data collected in the Prevention Needs Assessment (PNA) survey in 2011 to PNA 2013 data. We also assessed predictors of continued tanning after passage of the bill. Results. Prior to the passage of Senate Bill 41, 12% of students reported at least one incident of indoor tanning in the past 12 months. After passage, only 7% of students reported indoor tanning in the past 12 months (P < 0.0001). Students who continued indoor tanning were more likely to be older and female and to engage in other risk behaviors, including smoking and alcohol use. Lower parental education levels were also associated with continued tanning. Conclusion. Indoor tanning restrictions showed beneficial impact on tanning rates in adolescents in Utah. Stricter restrictions may show even greater impact than restrictions that allow for parental waivers. Stronger enforcement of bans is needed to further reduce youth access. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"839601"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/839601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32662843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Sun Protection Beliefs among Hispanics in the US. 美国西班牙裔美国人的防晒信仰
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-11-09 DOI: 10.1155/2014/161960
Marimer Santiago-Rivas, Chang Wang, Lina Jandorf
{"title":"Sun Protection Beliefs among Hispanics in the US.","authors":"Marimer Santiago-Rivas,&nbsp;Chang Wang,&nbsp;Lina Jandorf","doi":"10.1155/2014/161960","DOIUrl":"https://doi.org/10.1155/2014/161960","url":null,"abstract":"<p><p>Purpose. We reviewed the literature on sun protection beliefs in Hispanics living in the United States to explore what challenges are faced by area of research. Method. A review of PubMED, PsycINFO, and CINAHL databases was performed. Studies were published in peer-reviewed journals (in all years available) and written in English. The search terms used were [\"skin cancer\" OR \"sun protection\"] AND [\"Latino\" OR \"Hispanic\"] AND \"beliefs.\" Eligible papers were included in the final analysis after meeting the following inclusion criteria: (1) the records had to quantitatively examine and report sun protection beliefs in Hispanics, (2) the number of Hispanic participants in the sample had to be clearly specified, and (3) studies reporting differences in sun protection beliefs between Hispanics and other racial and ethnic groups were included in the review. Results. Of the 92 articles identified, 11 met inclusion criteria and addressed sun protection beliefs regarding skin cancer seriousness and susceptibility, and benefits and barriers of sun protection and skin cancer risk behaviors. Characteristics of studies and results were examined. Conclusion. There is insufficient evidence to determine a pattern of sun protection beliefs among Hispanics in the United States. More quality studies are needed which focus on sun protection beliefs in Hispanics. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"161960"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/161960","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32844359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
The experience of melanoma follow-up care: an online survey of patients in australia. 黑素瘤随访护理的经验:澳大利亚患者的在线调查。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-11-19 DOI: 10.1155/2014/429149
Janine Mitchell, Peta Callaghan, Jackie Street, Susan Neuhaus, Taryn Bessen
{"title":"The experience of melanoma follow-up care: an online survey of patients in australia.","authors":"Janine Mitchell,&nbsp;Peta Callaghan,&nbsp;Jackie Street,&nbsp;Susan Neuhaus,&nbsp;Taryn Bessen","doi":"10.1155/2014/429149","DOIUrl":"https://doi.org/10.1155/2014/429149","url":null,"abstract":"<p><p>Investigating patients' reports on the quality and consistency of melanoma follow-up care in Australia would assist in evaluating if this care is effective and meeting patients' needs. The objective of this study was to obtain and explore the patients' account of the technical and interpersonal aspects of melanoma follow-up care received. An online survey was conducted to acquire details of patients' experience. Participants were patients treated in Australia for primary melanoma. Qualitative and quantitative data about patient perceptions of the nature and quality of their follow-up care were collected, including provision of melanoma specific information, psychosocial support, and imaging tests received. Inconsistencies were reported in the provision and quality of care received. Patient satisfaction was generally low and provision of reassurance from health professionals was construed as an essential element of quality of care. \"Gaps\" in follow-up care for melanoma patients were identified, particularly provision of adequate psychosocial support and patient education. Focus on strategies for greater consistency in the provision of support, information, and investigations received, may generate a cost dividend which could be reinvested in preventive and supportive care and benefit patient well-being. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"429149"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/429149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32931667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Saphenous vein sparing superficial inguinal dissection in lower extremity melanoma. 保留隐静脉的下肢黑色素瘤腹股沟浅夹层。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-07-13 DOI: 10.1155/2014/652123
Muhammed Beşir Oztürk, Arzu Akan, Ozay Ozkaya, Onur Egemen, Ali Rıza Oreroğlu, Turgut Kayadibi, Mithat Akan
{"title":"Saphenous vein sparing superficial inguinal dissection in lower extremity melanoma.","authors":"Muhammed Beşir Oztürk,&nbsp;Arzu Akan,&nbsp;Ozay Ozkaya,&nbsp;Onur Egemen,&nbsp;Ali Rıza Oreroğlu,&nbsp;Turgut Kayadibi,&nbsp;Mithat Akan","doi":"10.1155/2014/652123","DOIUrl":"https://doi.org/10.1155/2014/652123","url":null,"abstract":"<p><p>Aim. The classic inguinal lymph node dissection is the main step for the regional control of the lower extremity melanoma, but this surgical procedure is associated with significant postoperative morbidity. The permanent lymphedema is the most devastating long-term complication leading to a significant decrease in the patient's quality of life. In this study we present our experience with modified, saphenous vein sparing, inguinal lymph node dissections for patients with melanoma of the lower extremity. Methods. Twenty one patients (10 women, 11 men) who underwent saphenous vein sparing superficial inguinal lymph node dissection for the melanoma of lower extremity were included in this study. The effects of saphenous vein sparing on postoperative complications were evaluated. Results. We have observed the decreased rate of long-term lymphedema in patients undergoing inguinal lymphadenectomy for the lower extremity melanoma. Conclusion. The inguinal lymphadenectomy with saphenous vein preservation in lower extremity melanoma patients seems to be an oncologically safe procedure and it may offer reduced long-term morbidity. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"652123"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/652123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32587967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study. 内部恶性肿瘤皮肤转移的临床病理和免疫组织化学相关性:一项为期五年的研究。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-08-25 DOI: 10.1155/2014/793937
Sarita Nibhoria, Kanwardeep Kaur Tiwana, Manmeet Kaur, Sumir Kumar
{"title":"A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study.","authors":"Sarita Nibhoria,&nbsp;Kanwardeep Kaur Tiwana,&nbsp;Manmeet Kaur,&nbsp;Sumir Kumar","doi":"10.1155/2014/793937","DOIUrl":"https://doi.org/10.1155/2014/793937","url":null,"abstract":"Cutaneous metastases from internal malignancies are uncommon and occur in 0.6%–10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian population and cutaneous metastases are quite rare. Cutaneous metastases carry a poor prognosis with average survival of few months. In the present five-year study 1924 malignant tumors were screened which included only nine cases of cutaneous metastatic deposits. A wide range of site and clinical presentations including nodules, plaques, and ulcers was noted. Histopathological findings were significant and corresponded with the primary internal malignancy. Cutaneous metastases from breast carcinoma (44.4%) were the most common finding followed by non-Hodgkin lymphoma and renal cell carcinoma (22.2% each) and carcinoma cervix (11.1%). The aim of our study is to classify the cutaneous metastases and to evaluate their clinicopathologic and immunohistochemical correlation with the primary tumor.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"793937"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/793937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32662842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Gene expression differences predict treatment outcome of merkel cell carcinoma patients. 基因表达差异预测默克尔细胞癌患者的治疗结果。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-01-30 DOI: 10.1155/2014/596459
Loren Masterson, Bryan J Thibodeau, Laura E Fortier, Timothy J Geddes, Barbara L Pruetz, Rajwant Malhotra, Richard Keidan, George D Wilson
{"title":"Gene expression differences predict treatment outcome of merkel cell carcinoma patients.","authors":"Loren Masterson,&nbsp;Bryan J Thibodeau,&nbsp;Laura E Fortier,&nbsp;Timothy J Geddes,&nbsp;Barbara L Pruetz,&nbsp;Rajwant Malhotra,&nbsp;Richard Keidan,&nbsp;George D Wilson","doi":"10.1155/2014/596459","DOIUrl":"https://doi.org/10.1155/2014/596459","url":null,"abstract":"<p><p>Due to the rarity of Merkel cell carcinoma (MCC), prospective clinical trials have not been practical. This study aimed to identify biomarkers with prognostic significance. While sixty-two patients were identified who were treated for MCC at our institution, only seventeen patients had adequate formalin-fixed paraffin-embedded archival tissue and followup to be included in the study. Patients were stratified into good, moderate, or poor prognosis. Laser capture microdissection was used to isolate tumor cells for subsequent RNA isolation and gene expression analysis with Affymetrix GeneChip Human Exon 1.0 ST arrays. Among the 191 genes demonstrating significant differential expression between prognostic groups, keratin 20 and neurofilament protein have previously been identified in studies of MCC and were significantly upregulated in tumors from patients with a poor prognosis. Immunohistochemistry further established that keratin 20 was overexpressed in the poor prognosis tumors. In addition, novel genes of interest such as phospholipase A2 group X, kinesin family member 3A, tumor protein D52, mucin 1, and KIT were upregulated in specimens from patients with poor prognosis. Our pilot study identified several gene expression differences which could be used in the future as prognostic biomarkers in MCC patients. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"596459"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/596459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32179811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
The pink rim sign: location of pink as an indicator of melanoma in dermoscopic images. 粉红色边缘标志:在皮肤镜图像中,粉红色作为黑色素瘤的指示。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-02-03 DOI: 10.1155/2014/719740
Ryan K Rader, Katie S Payne, Uday Guntupalli, Harold S Rabinovitz, Maggie C Oliviero, Rhett J Drugge, Joseph J Malters, William V Stoecker
{"title":"The pink rim sign: location of pink as an indicator of melanoma in dermoscopic images.","authors":"Ryan K Rader,&nbsp;Katie S Payne,&nbsp;Uday Guntupalli,&nbsp;Harold S Rabinovitz,&nbsp;Maggie C Oliviero,&nbsp;Rhett J Drugge,&nbsp;Joseph J Malters,&nbsp;William V Stoecker","doi":"10.1155/2014/719740","DOIUrl":"https://doi.org/10.1155/2014/719740","url":null,"abstract":"<p><p>Background. In dermoscopic images, multiple shades of pink have been described in melanoma without specifying location of these areas within the lesion. Objective. The purpose of this study was to determine the statistics for the presence of centrally and peripherally located pink melanoma and benign melanocytic lesions. Methods. Three observers, untrained in dermoscopy, each retrospectively analyzed 1290 dermoscopic images (296 melanomas (170 in situ and 126 invasive), 994 benign melanocytic nevi) and assessed the presence of any shade of pink in the center and periphery of the lesion. Results. Pink was located in the peripheral region in 14.5% of melanomas and 6.3% of benign melanocytic lesions, yielding an odds ratio of 2.51 (95% CI: 1.7-3.8, P < 0.0001). Central pink was located in 12.8% of melanomas and 21.8% of benign lesions, yielding an odds ratio of 0.462 (95% CI: 0.67, P = 0.204). Pink in melanoma in situ tended to be present throughout the lesion (68% of pink lesions). Pink in invasive melanoma was present in 17% of cases, often presenting as a pink rim. Conclusions. The presence of pink in the periphery or rim of a dermoscopic melanocytic lesion image provides an indication of malignancy. We offer the \"pink rim sign\" as a clue to the dermoscopic diagnosis of invasive melanoma. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"719740"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/719740","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32184641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Validity and stability of the decisional balance for sun protection inventory. 防晒产品库存决策平衡的有效性和稳定性。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-12-07 DOI: 10.1155/2014/190541
Hui-Qing Yin, Joseph S Rossi, Colleen A Redding, Andrea L Paiva, Steven F Babbin, Wayne F Velicer
{"title":"Validity and stability of the decisional balance for sun protection inventory.","authors":"Hui-Qing Yin,&nbsp;Joseph S Rossi,&nbsp;Colleen A Redding,&nbsp;Andrea L Paiva,&nbsp;Steven F Babbin,&nbsp;Wayne F Velicer","doi":"10.1155/2014/190541","DOIUrl":"https://doi.org/10.1155/2014/190541","url":null,"abstract":"<p><p>The 8-item Decisional Balance for sun protection inventory (SunDB) assesses the relative importance of the perceived advantages (Pros) and disadvantages (Cons) of sun protective behaviors. This study examined the psychometric properties of the SunDB measure, including invariance of the measurement model, in a population-based sample of N = 1336 adults. Confirmatory factor analyses supported the theoretically based 2-factor (Pros, Cons) model, with high internal consistencies for each subscale (α ≥ .70). Multiple-sample CFA established that this factor pattern was invariant across multiple population subgroups, including gender, racial identity, age, education level, and stage of change subgroups. Multivariate analysis by stage of change replicated expected patterns for SunDB (Pros η (2) = .15, Cons η (2) = .02). These results demonstrate the internal and external validity and measurement stability of the SunDB instrument in adults, supporting its use in research and intervention. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"190541"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/190541","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32940780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Melanoma Development and Progression Are Associated with Rad6 Upregulation and β -Catenin Relocation to the Cell Membrane. 黑色素瘤的发生和发展与Rad6上调和β -Catenin迁移到细胞膜有关。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-05-06 DOI: 10.1155/2014/439205
Karli Rosner, Darius R Mehregan, Evangelia Kirou, Judith Abrams, Seongho Kim, Michelle Campbell, Jillian Frieder, Kelsey Lawrence, Brittany Haynes, Malathy P V Shekhar
{"title":"Melanoma Development and Progression Are Associated with Rad6 Upregulation and β -Catenin Relocation to the Cell Membrane.","authors":"Karli Rosner,&nbsp;Darius R Mehregan,&nbsp;Evangelia Kirou,&nbsp;Judith Abrams,&nbsp;Seongho Kim,&nbsp;Michelle Campbell,&nbsp;Jillian Frieder,&nbsp;Kelsey Lawrence,&nbsp;Brittany Haynes,&nbsp;Malathy P V Shekhar","doi":"10.1155/2014/439205","DOIUrl":"https://doi.org/10.1155/2014/439205","url":null,"abstract":"<p><p>We have previously demonstrated that Rad6 and β -catenin enhance each other's expression through a positive feedback loop to promote breast cancer development/progression. While β -catenin has been implicated in melanoma pathogenesis, Rad6 function has not been investigated. Here, we examined the relationship between Rad6 and β -catenin in melanoma development and progression. Eighty-eight cutaneous tumors, 30 nevi, 29 primary melanoma, and 29 metastatic melanomas, were immunostained with anti- β -catenin and anti-Rad6 antibodies. Strong expression of Rad6 was observed in only 27% of nevi as compared to 100% of primary and 96% of metastatic melanomas. β -Catenin was strongly expressed in 97% of primary and 93% of metastatic melanomas, and unlike Rad6, in 93% of nevi. None of the tumors expressed nuclear β -catenin. β -Catenin was exclusively localized on the cell membrane of 55% of primary, 62% of metastatic melanomas, and only 10% of nevi. Cytoplasmic β -catenin was detected in 90% of nevi, 17% of primary, and 8% of metastatic melanoma, whereas 28% of primary and 30% of metastatic melanomas exhibited β -catenin at both locations. These data suggest that melanoma development and progression are associated with Rad6 upregulation and membranous redistribution of β -catenin and that β -catenin and Rad6 play independent roles in melanoma development. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"439205"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/439205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32394086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Six years of experience in photodynamic therapy for Basal cell carcinoma: results and fluorescence diagnosis from 191 lesions. 基底细胞癌光动力治疗六年经验:191个病灶的结果和荧光诊断。
IF 1.1
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-09-14 DOI: 10.1155/2014/849248
M Fernández-Guarino, A Harto, B Pérez-García, A Royuela, P Jaén
{"title":"Six years of experience in photodynamic therapy for Basal cell carcinoma: results and fluorescence diagnosis from 191 lesions.","authors":"M Fernández-Guarino,&nbsp;A Harto,&nbsp;B Pérez-García,&nbsp;A Royuela,&nbsp;P Jaén","doi":"10.1155/2014/849248","DOIUrl":"https://doi.org/10.1155/2014/849248","url":null,"abstract":"<p><p>Background. Photodynamic therapy (PDT) has become a therapeutic option for basal cell carcinoma (BCC) in the last decade. Objectives. To study the results and predictors of BCC response to treatment with PDT and to evaluate fluorescence diagnosis of BCC. Methods. A descriptive, retrospective, and observational study was carried out. Patients with biopsy-confirmed BCC who were treated with methyl aminolevulinate and red light according to standard treatment protocols (2 sessions separated by 2 weeks, 630 nm, 37 J/cm(2), 8 minutes, Aktilite) were selected. Response was scored as clinically complete and incomplete and the patients were followed up every three months. Results. Data from 191 BCC in 181 patients with a mean age of 69.55 years and a mean follow-up period of 34.4 months were collected. The overall response was 74% of the BCC treated, with the best response in superficial BCC with a 95% of complete response. The regression analysis revealed that the superficial histological type was the primary factor predictive of a complete response. Conclusions. In the treatment of BCC with PDT, the most significant factor for predicting response is the histological type. </p>","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2014 ","pages":"849248"},"PeriodicalIF":1.1,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/849248","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32735194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
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