内部恶性肿瘤皮肤转移的临床病理和免疫组织化学相关性:一项为期五年的研究。

IF 1.2 Q3 DERMATOLOGY
Journal of Skin Cancer Pub Date : 2014-01-01 Epub Date: 2014-08-25 DOI:10.1155/2014/793937
Sarita Nibhoria, Kanwardeep Kaur Tiwana, Manmeet Kaur, Sumir Kumar
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引用次数: 14

摘要

内部恶性肿瘤的皮肤转移并不常见,发生率为所有癌症患者的0.6%-10.4%。在大多数病例中,皮肤转移发生在原发性内部恶性肿瘤的初步诊断之后和病程晚期。皮肤肿瘤在亚洲人群中并不常见,皮肤转移也相当罕见。皮肤转移的预后较差,平均生存期只有几个月。在目前为期五年的研究中,共筛查了1924例恶性肿瘤,其中只有9例皮肤转移性沉积。广泛的部位和临床表现包括结节、斑块和溃疡。组织病理学结果显著,符合原发性内部恶性肿瘤。最常见的是乳腺癌的皮肤转移(44.4%),其次是非霍奇金淋巴瘤和肾细胞癌(各22.2%)和子宫颈癌(11.1%)。我们研究的目的是对皮肤转移进行分类,并评估其与原发肿瘤的临床病理和免疫组织化学相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study.

A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study.

A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study.

A clinicopathological and immunohistochemical correlation in cutaneous metastases from internal malignancies: a five-year study.
Cutaneous metastases from internal malignancies are uncommon and occur in 0.6%–10.4% of all patients with cancer. In most cases, cutaneous metastases develop after the initial diagnosis of the primary internal malignancy and late in the course of the disease. Skin tumors are infrequent in Asian population and cutaneous metastases are quite rare. Cutaneous metastases carry a poor prognosis with average survival of few months. In the present five-year study 1924 malignant tumors were screened which included only nine cases of cutaneous metastatic deposits. A wide range of site and clinical presentations including nodules, plaques, and ulcers was noted. Histopathological findings were significant and corresponded with the primary internal malignancy. Cutaneous metastases from breast carcinoma (44.4%) were the most common finding followed by non-Hodgkin lymphoma and renal cell carcinoma (22.2% each) and carcinoma cervix (11.1%). The aim of our study is to classify the cutaneous metastases and to evaluate their clinicopathologic and immunohistochemical correlation with the primary tumor.
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来源期刊
Journal of Skin Cancer
Journal of Skin Cancer DERMATOLOGY-
CiteScore
2.30
自引率
18.20%
发文量
12
审稿时长
21 weeks
期刊介绍: Journal of Skin Cancer is a peer-reviewed, Open Access journal that publishes clinical and translational research on the detection, diagnosis, prevention, and treatment of skin malignancies. The journal encourages the submission of original research articles, review articles, and clinical studies related to pathology, prognostic indicators and biomarkers, novel therapies, as well as drug sensitivity and resistance.
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