Journal of Skin Cancer最新文献_第5页

Clinical and Demographic Features of Basal Cell Carcinoma in North Jordan. 北约旦基底细胞癌的临床和人口学特征。

IF 1.1

Journal of Skin Cancer Pub Date : 2018-10-04 eCollection Date: 2018-01-01 DOI: 10.1155/2018/2624054

Firas Al-Qarqaz, Maha Marji, Khaldon Bodoor, Rowida Almomani, Wisam Al Gargaz, Diala Alshiyab, Jihan Muhaidat, Mohammad Alqudah

{"title":"Clinical and Demographic Features of Basal Cell Carcinoma in North Jordan.","authors":"Firas Al-Qarqaz, Maha Marji, Khaldon Bodoor, Rowida Almomani, Wisam Al Gargaz, Diala Alshiyab, Jihan Muhaidat, Mohammad Alqudah","doi":"10.1155/2018/2624054","DOIUrl":"https://doi.org/10.1155/2018/2624054","url":null,"abstract":"Basal cell carcinoma (BCC) is the most common cancer affecting humans. It almost has no tendency for metastasis; however it can be destructive to surrounding tissue. Patients with darker skin colors have lower risk of developing skin cancers and the clinical characteristics may differ from populations with lighter skin colors. Methods. This is a retrospective clinical study (2003-2017). Data on age, gender, and location of tumor were collected and analyzed. Results. 335 cases were identified. Males tend to get BCC at a younger age than females. Face was the most common site in both males and females. Cheeks and nose were the most likely areas of the face to be involved. Scalp was the most common extrafacial site to be involved in males; however in females scalp was much less likely to be involved. Conclusion. BCC is less common in populations with darker skin. Males were more affected and at an earlier age compared to females. Facial skin followed by scalp was the most common site affected. Skin phototype, cultural and religious dress type, and different sun exposure behavior may explain many of the clinical and demographic findings related to BCC in patients with darker skin tones.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2018 ","pages":"2624054"},"PeriodicalIF":1.1,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2624054","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36737637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol. 基底鳞状癌:单中心临床病理评估和循证方案建议。

IF 1.1

Journal of Skin Cancer Pub Date : 2018-06-03 eCollection Date: 2018-01-01 DOI: 10.1155/2018/6061395

Jordan W Oldbury, Richard A J Wain, Sameera Abas, Christopher M Dobson, Srinivasan S Iyer

{"title":"Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol.","authors":"Jordan W Oldbury, Richard A J Wain, Sameera Abas, Christopher M Dobson, Srinivasan S Iyer","doi":"10.1155/2018/6061395","DOIUrl":"https://doi.org/10.1155/2018/6061395","url":null,"abstract":"Basosquamous carcinoma (BSC) is an uncommon skin malignancy with significant invasive and metastatic potential. There are currently no clear management guidelines. This study evaluates the management and outcomes of patients diagnosed with BSC over a 7-year period. We present an evidence-based unit protocol for the management of BSC. All patients treated for BSC between 2009 and 2015 were reviewed. Data collected included patient demographics, tumour-specific information, management strategy, presence of recurrence or metastasis, and details of follow-up. 74 patients were identified, making this one of the largest cohorts of BSC patients reported. Mean age at diagnosis was 75.4 years, with a male:female ratio of 1.6:1. The most common tumour site was the head and neck (n=43, 58.1%). All tumours were graded at pT1 (n=51) or pT2 (n=23). Inadequate excision occurred in 17 patients (23%). Mean excision margins were >4mm peripherally and deep. Inadequately excised BSCs were further treated with wide local excision (n=6) or radiotherapy (n=5), or both (n=1). There were no cases of local recurrence or metastatic disease. This study demonstrates a cohort of patients with BSCs that appear less aggressive than previously reported. Current management with surgical excision appears to produce adequate results. However, an evidence-based guideline is still lacking.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2018 ","pages":"6061395"},"PeriodicalIF":1.1,"publicationDate":"2018-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6061395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36285518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Essential Components of Melanoma Histopathological Reporting: The Surgical Oncologist's Perspective. 黑色素瘤组织病理学报告的基本组成部分:外科肿瘤学家的观点。

IF 1.1

Journal of Skin Cancer Pub Date : 2018-05-02 eCollection Date: 2018-01-01 DOI: 10.1155/2018/9838410

Vinka Nurdjaja, Masato Yozu, Jon A Mathy

引用次数: 5

Predictors of Sun Protective Behaviors among Latino Day Laborers. 拉丁裔日工防晒行为的预测因素。

IF 1.1

Journal of Skin Cancer Pub Date : 2018-01-28 eCollection Date: 2018-01-01 DOI: 10.1155/2018/3454309

Javier F Boyas, Vinayak K Nahar

{"title":"Predictors of Sun Protective Behaviors among Latino Day Laborers.","authors":"Javier F Boyas, Vinayak K Nahar","doi":"10.1155/2018/3454309","DOIUrl":"https://doi.org/10.1155/2018/3454309","url":null,"abstract":"Objectives: Despite the substantial solar ultraviolet radiation experienced by Latino day laborers, little attention has been given to factors that are associated with sun protective behaviors. The purpose of this study was to examine psychological and nonpsychological predictors of sun protective behaviors among Latino day laborers.Methods: This cross-sectional study included a nonrandom sample of 137 Latino day laborers recruited from Mississippi and Illinois. Participants completed a self-report survey instrument, available in English and Spanish, on sun protective behaviors.Results: Multivariate regression results showed that sun protective behaviors were significantly greater among Latino day laborers: (a) who had greater perceptions that their supervisor also engaged in sun protective behaviors (β = 0.25, p ≤ 0.01); (b) who reported higher levels of health literacy (β = 0.23, p ≤ 0.001); (c) who have greater knowledge of skin cancer risk factors (β = 0.21, p ≤ 0.01); and (d) who have skin tone that was self-perceived to be more prone to sunburns (β = 0.19, p ≤ 0.01).Conclusions: Latino day laborers possess marginal levels of skin cancer knowledge and engage minimally in sun protective behaviors. Skin cancer prevention interventions are warranted for this high-risk group, particularly in the locations in which Latino day laborers work.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2018 ","pages":"3454309"},"PeriodicalIF":1.1,"publicationDate":"2018-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/3454309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35981716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management. 免疫毒性与检查点抑制转移性黑色素瘤:病例系列和临床管理。

IF 1.1

Journal of Skin Cancer Pub Date : 2018-01-21 eCollection Date: 2018-01-01 DOI: 10.1155/2018/9602540

Anna J Lomax, Jennifer Lim, Robert Cheng, Arianne Sweeting, Patricia Lowe, Neil McGill, Nicholas Shackel, Elizabeth L Chua, Catriona McNeil

{"title":"Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management.","authors":"Anna J Lomax, Jennifer Lim, Robert Cheng, Arianne Sweeting, Patricia Lowe, Neil McGill, Nicholas Shackel, Elizabeth L Chua, Catriona McNeil","doi":"10.1155/2018/9602540","DOIUrl":"https://doi.org/10.1155/2018/9602540","url":null,"abstract":"Immune checkpoint inhibitors (anti-PD-1 and anti-CTLA-4 antibodies) are a standard of care for advanced melanoma. Novel toxicities comprise immune-related adverse events (irAE). With increasing use, irAE require recognition, practical management strategies, and multidisciplinary care. We retrospectively evaluated the incidence, kinetics, and management of irAE in 41 patients receiving anti-PD-1 antibody therapy (pembrolizumab) for advanced melanoma. 63% received prior anti-CTLA-4 antibody therapy (ipilimumab). IrAE occurred in 54%, most commonly dermatological (24%), rheumatological (22%), and thyroid dysfunction (12%). Thyroiditis was characterised by a brief asymptomatic hyperthyroid phase followed by a symptomatic hypothyroid phase requiring thyroxine replacement. Transplant rejection doses of methylprednisolone were necessary to manage refractory hepatotoxicity. A bullous pemphigoid-like skin reaction with refractory pruritus responded to corticosteroids and neuropathic analgesia. Disabling grade 3-4 oligoarthritis required sulfasalazine therapy in combination with steroids. The median interval between the last dose of anti-CTLA-4 antibody and the first dose of anti-PD-1 therapy was 2.0 months (range: 0.4 to 22.4). Toxicities may occur late; this requires vigilance and multidisciplinary management which may allow effective anticancer therapy to continue. Management algorithms for thyroiditis, hypophysitis, arthralgia/arthritis, colitis, steroid-refractory hepatitis, and skin toxicity are discussed.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2018 ","pages":"9602540"},"PeriodicalIF":1.1,"publicationDate":"2018-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/9602540","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35970102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Unintended Sunburn: A Potential Target for Sun Protection Messages. 意外晒伤：防晒信息的潜在目标。

IF 1.1

Journal of Skin Cancer Pub Date : 2017-01-01 Epub Date: 2017-04-03 DOI: 10.1155/2017/6902942

Geraldine F H McLeod, Anthony I Reeder, Andrew R Gray, Rob McGee

{"title":"Unintended Sunburn: A Potential Target for Sun Protection Messages.","authors":"Geraldine F H McLeod, Anthony I Reeder, Andrew R Gray, Rob McGee","doi":"10.1155/2017/6902942","DOIUrl":"10.1155/2017/6902942","url":null,"abstract":"New Zealand (NZ) has the highest melanoma incidence rate in the world. Primary prevention efforts focus on reducing sunburn incidence and increasing sun protective practices in the population. However, sunburn from excessive ultraviolet radiation (UVR) remains common. To reduce sunburn incidence, it is important to examine those individuals who experience unintended sunburn. This study aims to use data from the NZ Triennial Sun Protection Survey to describe respondents who were not intending to tan but were sunburnt after outdoor UVR exposure. Information on sociodemographics, concurrent weather conditions, sun protection attitudes and knowledge, and outdoor behaviour was also collected. The results showed 13.5% of respondents' experienced unintended sunburn during the survey weekend but had not attempted to obtain a tan that summer. Respondents who reported unintended sunburn were more likely than others to have been near water and in unshaded areas, used sunscreen, had higher SunSmart knowledge scores, had lower positive attitudes towards tanning, and were outdoors for a longer duration with less body coverage. As sunburn was unintended these respondents' outdoor sun protective behaviours may be amenable to change. Future public health initiatives should focus on increasing sun protection (clothing and shade) and reducing potential barriers to sun protection.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2017 ","pages":"6902942"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34969009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microvessel Density in Patients with Cutaneous Melanoma: An Up-to-Date Systematic Review and Meta-Analysis. 皮肤黑色素瘤患者的微血管密度:最新的系统回顾和荟萃分析。

IF 1.1

Journal of Skin Cancer Pub Date : 2017-01-01 Epub Date: 2017-12-26 DOI: 10.1155/2017/2049140

Konstantinos Perivoliotis, Panagiotis Ntellas, Katerina Dadouli, Prodromos Koutoukoglou, Maria Ioannou, Konstantinos Tepetes

{"title":"Microvessel Density in Patients with Cutaneous Melanoma: An Up-to-Date Systematic Review and Meta-Analysis.","authors":"Konstantinos Perivoliotis, Panagiotis Ntellas, Katerina Dadouli, Prodromos Koutoukoglou, Maria Ioannou, Konstantinos Tepetes","doi":"10.1155/2017/2049140","DOIUrl":"https://doi.org/10.1155/2017/2049140","url":null,"abstract":"Background: We conducted a meta-analysis, in order to appraise the effect of microvessel density (MVD) on the survival of patients with cutaneous melanoma.Methods: This study was conducted according to the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic literature search in electronic databases (MEDLINE, Web of Science, and Cochrane Central Register of Controlled Clinical Trials) was performed. Fixed Effects or Random Effects model was used, based on the Cochran Q test.Results: In total 9 studies (903 patients) were included. Pooled HR for overall survival (OS) and disease-free survival (DFS) were 2.62 (95% CI: 0.71-9.60, p = 0.15) and 2.64 (95% CI: 0.82-8.47, p = 0.10), respectively. Odds ratios of overall survival between high and low MVD groups, at 12 (1.45, 95% CI: 0.16-13.24), 36 (2.93, 95% CI: 0.63-13.59), and 60 (4.09, 95% CI: 0.85-19.77) months did not reach statistical significance. Significant superiority of low MVD group, in terms of DFS, at all time intervals (OR: 4.69, p < 0.0001; OR: 2.18, p = 0.004; OR: 7.46, p = 0.01, resp.) was documented.Discussion: MVD does not affect the HR of OS and DFS. A strong correlation with DFS rates at 12, 36, and 60 months was recorded.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2017 ","pages":"2049140"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2049140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35828878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

A Matching-Adjusted Indirect Comparison of Sonidegib and Vismodegib in Advanced Basal Cell Carcinoma. Sonidegib和Vismodegib治疗晚期基底细胞癌的间接比较。

IF 1.1

Journal of Skin Cancer Pub Date : 2017-01-01 Epub Date: 2017-05-21 DOI: 10.1155/2017/6121760

Dawn Odom, Deirdre Mladsi, Molly Purser, James A Kaye, Eirini Palaka, Alina Charter, Jo Annah Jensen, Dalila Sellami

{"title":"A Matching-Adjusted Indirect Comparison of Sonidegib and Vismodegib in Advanced Basal Cell Carcinoma.","authors":"Dawn Odom, Deirdre Mladsi, Molly Purser, James A Kaye, Eirini Palaka, Alina Charter, Jo Annah Jensen, Dalila Sellami","doi":"10.1155/2017/6121760","DOIUrl":"10.1155/2017/6121760","url":null,"abstract":"Objectives: Based on single-arm trial data (BOLT), sonidegib was approved in the US and EU to treat locally advanced basal cell carcinomas (BCCs) ineligible for curative surgery or radiotherapy. Vismodegib, the other approved targeted therapy, also was assessed in a single-arm trial (ERIVANCE). We examined the comparative effectiveness of the two drugs using a matching-adjusted indirect comparison (MAIC) versus an unadjusted indirect comparison.Methods: After comparing trials and identifying potential prognostic factors, an MAIC was conducted to adjust for differences in key patient baseline characteristics. Due to BOLT's small sample size, the number of matching variables was restricted to two. Efficacy results for sonidegib were generated so that selected baseline characteristics matched those from ERIVANCE and were compared with published ERIVANCE results.Results: Matching variables were baseline percentages of patients receiving prior radiotherapy and surgery. After weighting, sonidegib objective response rate (ORR) and median progression-free survival (PFS) were effectively unchanged (prematched versus postmatched ORR and PFS, 56.1% versus 56.7% and 22.1 versus 22.1 months, resp.). Vismodegib's ORR and PFS were 47.6% and 9.5 months.Conclusions: Comparative effectiveness of sonidegib versus vismodegib remains unchanged after adjusting BOLT patient-level data to match published ERIVANCE baseline percentages of patients receiving prior surgery and radiotherapy.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2017 ","pages":"6121760"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/6121760","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35084092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Perceptions and Practices of the Iranian Population regarding Skin Cancers: A Literature Review. 伊朗人对皮肤癌的看法和做法:文献综述。

IF 1.1

Journal of Skin Cancer Pub Date : 2017-01-01 Epub Date: 2017-11-19 DOI: 10.1155/2017/4934108

Vinayak K Nahar, Zachria Hasani, Brian Martin, Javier F Boyas, Rosa Chabok, Leena S Philip, Ghazal Ghafari, Leila Seidfaraji, Stacy Chelf, Ram Lakhan, Amanda H Wilkerson, Marcelle Savoy, Manoj Sharma

{"title":"Perceptions and Practices of the Iranian Population regarding Skin Cancers: A Literature Review.","authors":"Vinayak K Nahar, Zachria Hasani, Brian Martin, Javier F Boyas, Rosa Chabok, Leena S Philip, Ghazal Ghafari, Leila Seidfaraji, Stacy Chelf, Ram Lakhan, Amanda H Wilkerson, Marcelle Savoy, Manoj Sharma","doi":"10.1155/2017/4934108","DOIUrl":"https://doi.org/10.1155/2017/4934108","url":null,"abstract":"Despite being preventable, more than 15% of all cancer cases in Iran occur in the skin, making them the most commonly diagnosed malignancy in the country. The purpose of this study is to gain an insight into the current skin cancer related knowledge, attitudes, beliefs, and practices among the Iranian population. A systematic computer based literature search was conducted using databases for articles published through April 2017. Research studies included those that measured skin cancer or sun protection related knowledge, attitudes, beliefs, and behaviors in different Iranian population groups. Exclusion criteria for the articles included (1) irrelevant topics to the review article's aim, (2) articles that focused on the treatment of skin cancers instead of prevention practices, and (3) similar studies conducted on populations not indigenous to Iran. A total of 25 articles that met the eligibility criteria were included in the review. Predominant data were collected via questionnaires. Skin cancer related knowledge varied from low to high across the studies. Moreover, there was a pattern of low perceived skin cancer susceptibility and severity. Overall, there was low usage of sun protection methods among the Iranian population. The findings of this study show that efforts to prevent skin cancer are needed. Education concerning the dangers of sun exposure as well as strategies used to prevent or lower the risk of developing skin cancer should be stressed.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2017 ","pages":"4934108"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/4934108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35749491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma. BEREP4免疫组化染色在基底细胞癌检测中的应用。

IF 1.1

Journal of Skin Cancer Pub Date : 2017-01-01 Epub Date: 2017-12-31 DOI: 10.1155/2017/2692604

Anthony Paulo Sunjaya, Angela Felicia Sunjaya, Sukmawati Tansil Tan

{"title":"The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma.","authors":"Anthony Paulo Sunjaya, Angela Felicia Sunjaya, Sukmawati Tansil Tan","doi":"10.1155/2017/2692604","DOIUrl":"https://doi.org/10.1155/2017/2692604","url":null,"abstract":"Basal Cell Carcinoma (BCC) is the most common type of malignant cancer found in the world today with a 3-10% increase in incidence each year. The American Cancer Society reported that 8 out of 10 patients with skin cancer are suffering from BCC with over 2 million new cases each year. BCC needs to be detected at the early stages to prevent local destruction causing disabilities to patients and increasing treatment costs. Furthermore, BCC patients who have undergone surgery are still at risk for recurrence, especially when the surgery performed fails to remove all the BCC cells, even when conventional histopathological testing after surgery has reported a surgically free margin. This review aims to evaluate studies on the use of BerEP4 immunohistochemistry staining on pathological sections of various types of BCC as well as its shortfalls. BerEP4 is a monoclonal antibody which detects specific epithelial-glycoprotein-adhesion-molecules (EpCAM) found on BCC cells. Various studies have shown that BerEP4 has a high sensitivity and specificity in detecting only BCC cells. The use of BerEP4 immunohistochemistry testing for the routine examination of cases of BCC is expected to be able to increase and improve early diagnosis as well as prevent recurrence after surgery.","PeriodicalId":17172,"journal":{"name":"Journal of Skin Cancer","volume":"2017 ","pages":"2692604"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/2692604","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35849384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22