Annah Tayebwa, Mohammad Neaz Morshed, Vincent Nierstrasz
{"title":"Waste textile decolorization using supercritical carbon dioxide (ScCO₂) technology: Design and optimization","authors":"Annah Tayebwa, Mohammad Neaz Morshed, Vincent Nierstrasz","doi":"10.1016/j.supflu.2025.106871","DOIUrl":"10.1016/j.supflu.2025.106871","url":null,"abstract":"<div><div>This report presents a dry and chemical free approach to waste textile decolorization using supercritical carbon dioxide (ScCO₂) technology. Dispersed dyed polyester (PET) fabrics was decolorized in a laboratory-scale ScCO₂ system with pristine PET serving as a dye absorbent guided by the principle of ScCO₂ dyeing. The influence of key process parameters such as time, temperature, pressure, and dyed-to-absorber fabric loading on extraction efficiency was analyzed through the equilibrium constant for dye partitioning. Results revealed that PET fabrics treated at 10:90 dyed-to-absorber loading under 120 °C, 25 MPa for 60 min exhibited the highest decolorization efficiency of (79 – 85) % for all dyes, reflected by the lowest color strength (K/S) values of 0.93 – 2.46. The equilibrium constant (Keq) increased with temperature, pressure, and absorber loading, reflecting improved dye partitioning efficiency. In an attempt to predict the thermodynamic behavior waste textile decolorization using ScCO₂, Peng-Robinson Equation of State (PR-EOS) was used to model the behavior and correlated with experimental values. Results showed modest qualitative agreement with experimental data with an AARD of 27–32 %. In general, the experimental finding of the report demonstrates the promising potential of ScCO₂-mediated decolorization of waste textile fabric, offering a dry, energy-efficient strategy supporting textile recycling.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"230 ","pages":"Article 106871"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145784679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis of glycerol carbonate via direct carbonation of glycerol in CO2 over Pd/CeO2/TiO2 catalyst","authors":"Awais Khalid, Satam Alotibi","doi":"10.1016/j.supflu.2025.106827","DOIUrl":"10.1016/j.supflu.2025.106827","url":null,"abstract":"<div><div>We report herein the effect of Pd loading supported over CeO<sub>2</sub>/TiO<sub>2</sub> nanocomposite for catalytic carbonation of glycerol with CO<sub>2</sub>. The synthesized catalyst was thoroughly characterized using various spectroscopic and microscopic techniques and overserved uniformly dispersed 1.5 % Pd nanoparticles of 5–20 nm showed improved conversion of glycerol to 34 % with 60 % glycerol carbonate selectivity at 150°C. Reaction parameters, such as temperature, CO<sub>2</sub> pressure, mmol of 2-cyanopyridine, and the reaction time, were investigated. Sheldon’s hot filtration test confirmed the catalyst’s heterogeneity with no leaching up to five consecutive cycles.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106827"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145404738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xu Lu , Xicheng Yang , Jia Zhang , Pengpeng Zhang , Qian Liu , Feng Zhou , Yanpei Sun , Hongjuan Zhang , Dongyin Chen , Yang Jin , Lina Chen
{"title":"A novel extract of Dendrobium flexicaule flower: Volatile components and neuroprotective potential","authors":"Xu Lu , Xicheng Yang , Jia Zhang , Pengpeng Zhang , Qian Liu , Feng Zhou , Yanpei Sun , Hongjuan Zhang , Dongyin Chen , Yang Jin , Lina Chen","doi":"10.1016/j.supflu.2025.106840","DOIUrl":"10.1016/j.supflu.2025.106840","url":null,"abstract":"<div><div>In recent years, the remarkable bioactivities and nutritional value of <em>Dendrobium flexicaule</em> flowers have become increasingly evident, underscoring their potential for broad applications. However, optimal extraction techniques and their health-promoting effects remain inadequately unexplored. This study investigated the neuroprotective effects of supercritical fluid-extracted DFF extract (DFFE), identified its key constituents, and elucidated underlying mechanisms via integrated <em>in vitro</em> and <em>in silico</em> approaches. Herein, the extract was obtained using supercritical fluid extraction (SFE), which demonstrated superior efficiency in preserving thermo-labile compounds and minimizing oxidative degradation compared to conventional ethanol reflux extraction, as evidenced by enhanced recovery of unsaturated fatty acids and sterols. Gas chromatography-mass spectrometry (GC-MS) analysis identified a total of 96 chemical constituents in DFFE. Notably, DFFE significantly mitigated glutamate-induced damage in PC12 cells by reducing LDH release, ROS generation, and enhancing antioxidant enzyme activity. Network pharmacology revealed linoleic acid, hexadecenoic acid, and pentadecanoic acid as core bioactive components, targeting PPARG, GSK3β, IL6, PTGS2, and MAPK3, which modulate Alzheimer’s and TNF signaling pathways. Molecular docking demonstrated stable interactions between most bioactive components and core targets through hydrogen bonds, with binding energies predominantly less than −5 kcal/mol. Ultimately, the extraction process was optimized using a decision tree model, which highlighted temperature and pressure as crucial parameters. Overall, these findings underscore DFFE’s potential as a neuroprotective agent for functional food or therapeutic development.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106840"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iván Navarro-Cárdenas, Andreas Kilzer, Eckhard Weidner, Marcus Petermann
{"title":"Phase behavior in heterogeneous catalytic hydrogenation of oils in supercritical fluids","authors":"Iván Navarro-Cárdenas, Andreas Kilzer, Eckhard Weidner, Marcus Petermann","doi":"10.1016/j.supflu.2025.106841","DOIUrl":"10.1016/j.supflu.2025.106841","url":null,"abstract":"<div><div>Conventional catalytic hydrogenation of oils is essentially constrained by mass-transfer resistance because of the poor solubility of hydrogen in liquid-phase substrates. Supercritical fluids (SCFs) offer a solution by creating a single, homogeneous reaction medium that dissolves both hydrogen and high-molecular-weight oils, thus overcoming the interfacial transport limitations. This review synthesizes several research to establish a unified framework for the supercritical hydrogenation of different feedstocks, including heavy oils, vegetable oils, and emerging streams like bio- and plastic-derived pyrolysis oils. The central goal of this work is to provide a deep understanding of phase behavior which is a critical aspect of the process design, directly influencing reaction rates, selectivity, and overall efficiency. By integrating principles of thermodynamics, heat and mass transfer, catalysis selection, and reactor design, this review provides applicable design metrics for developing a more suitable upgrading technology with higher space yield times for a wide spectrum of complex oils.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106841"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of drug loading onto MCM-48 via supercritical CO2 deposition: Effects of drug type, temperature, and silica structure","authors":"Yuto Asai, Ikuo Ushiki","doi":"10.1016/j.supflu.2025.106824","DOIUrl":"10.1016/j.supflu.2025.106824","url":null,"abstract":"<div><div>Mesoporous silica is a promising drug delivery carrier owing to its high surface area, tunable pores, and ability to stabilize amorphous drugs. In this study, supercritical fluid deposition (SCFD) using supercritical CO<sub>2</sub> (15 MPa) was employed to load ibuprofen and ketoprofen into MCM-48 mesoporous silica. The effects of drug type, temperature (313 K to 333 K), and silica framework were evaluated systematically. Transmission electron microscopy (TEM) and nitrogen adsorption confirmed that the three-dimensional cubic mesostructure of MCM-48 remained intact after impregnation. Fourier-transform infrared spectroscopy (FT-IR), and thermogravimetric analysis (TGA) verified the successful incorporation, with distinct thermal events indicating external and pore-confined adsorption. Ibuprofen consistently achieved higher loading than ketoprofen, driven by its greater solubility in supercritical CO<sub>2</sub>, indicating that solubility is the dominant factor over surface affinity. Temperature had only a modest influence owing to the opposing effects of decreased CO<sub>2</sub> density and reduced competitive CO<sub>2</sub> adsorption at higher temperatures. Compared with SBA-15, MCM-48 exhibited superior uptake across all conditions, which was attributed to its larger surface area and interconnected pore network. These results demonstrate that SCFD enables the efficient, solvent-free incorporation of active compounds while preserving mesostructural integrity, offering guidance for the design of high-performance mesoporous carriers in pharmaceutical and related applications.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106824"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145364356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The development of GelMA based hydrogels combined with acellular small intestinal submucosa for peripheral nerve injuries","authors":"Zeynep Caglar , Busra Kilic , Halil Murat Aydin","doi":"10.1016/j.supflu.2025.106842","DOIUrl":"10.1016/j.supflu.2025.106842","url":null,"abstract":"<div><div>Peripheral nerve injuries are a major public health concern. The slow self-regeneration of the complex structure of the peripheral nervous system significantly impacts functional recovery. For this reason, studies on nerve tissue engineering for peripheral nerve repair are critical. Here, we constructed a gelMA-based decellularized SIS hybrid construct to promote functional regeneration after peripheral nerve injury. A supercritical carbon dioxide (scCO<sub>2</sub>) decellularization protocol was developed for bovine small intestinal submucosa (SIS) decellularization. A conventional method involving the combinations of physical, chemical, and enzymatic treatments was used for evaluating the efficiency of the scCO<sub>2</sub> technology for SIS decellularization. The efficiency of decellularization methods was evaluated using both qualitative and quantitative analyses. In this regard, it was shown that the scCO<sub>2</sub> technology was an efficient and high-yielding method for the decellularization of SIS. Then, SIS was incubated with gelMA solutions to obtain hybrid hydrogels. FT-IR and SEM were used to prove the success of hybrid tissue scaffold synthesis as well as to investigate structural changes. The water retention capacity, degradation properties and mechanical strength of the hybrid scaffolds were investigated and compared with the acellular SIS. Lastly the ability of hybrid membranes to induce neural cell adhesion and proliferation was evaluated via <em>in vitro</em> cell culture of Schwann cells in terms of cell viability, proliferation and morphological changes.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106842"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Gallo, Marco Armandi, Fabiana Mangano, Silvia Ronchetti, Mauro Banchero, Luigi Manna
{"title":"Silica-alumina aerogels functionalized with amino-groups for the adsorption of CO2","authors":"Marta Gallo, Marco Armandi, Fabiana Mangano, Silvia Ronchetti, Mauro Banchero, Luigi Manna","doi":"10.1016/j.supflu.2025.106835","DOIUrl":"10.1016/j.supflu.2025.106835","url":null,"abstract":"<div><div>To overcome climate challenges, emerging CO<sub>2</sub> capture technologies focus on innovative solid sorbents, like aerogels. Silica aerogels, in particular, have emerged as an exceptional class of materials with unique properties even though their adsorption selectivity towards CO<sub>2</sub>, and their thermal and mechanical properties are limited. In this research, a hybrid silica-alumina aerogel has been prepared, to merge the elevated surface area typical of silica with the basic character (favorable to CO<sub>2</sub> adsorption) and the high thermal and mechanical resistance typical of alumina. For the first time, these silica-alumina aerogels were functionalized with 3-aminopropyltriethoxysilane (APTES) amino groups through a one-pot process. This approach was chosen to directly introduce functional groups during gel formation, reducing the number of post-synthesis steps. The functionalization with amino groups aims to strengthen the interactions with CO₂ molecules via acid–base interactions, thus enhancing adsorption capacity and selectivity. Three samples with increasing APTES content as well as a reference without any functionalization were prepared and characterized in terms of physico-chemical and adsorption properties. The results of CO<sub>2</sub> and N<sub>2</sub> adsorption tests as well as <em>in situ</em> FTIR suggest that low functionalization does not confer a significant advantage in CO<sub>2</sub> capture. Higher APTES contents, instead, lead to a significant increase in the total quantity of adsorbed CO<sub>2</sub> and in higher selectivity over N<sub>2</sub> (calculated according to the Ideal Adsorbed Solution Theory). Moreover, also the strength of interaction increases, since not only physisorption, but also chemisorption takes place.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106835"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145473167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guangyu Liu , Xinxin Fan , Cailin Wang , Junwen Chen , Shengzhu Zhang , Mingzhuo Li , Qihui Hu , Yuxing Li
{"title":"A mechanistic model for X65 steel corrosion in supercritical CO2 flow and phase change pipeline transportation environment","authors":"Guangyu Liu , Xinxin Fan , Cailin Wang , Junwen Chen , Shengzhu Zhang , Mingzhuo Li , Qihui Hu , Yuxing Li","doi":"10.1016/j.supflu.2025.106825","DOIUrl":"10.1016/j.supflu.2025.106825","url":null,"abstract":"<div><div>Phase transitions in long-distance CO<sub>2</sub> pipelines are inevitable, yet their coupled effects on corrosion under real pipeline flow conditions remain inadequately understood. This study systematically investigates the influence of phase transition and flow velocity on the corrosion mechanisms of X65 steel in CO<sub>2</sub> pipelines through corrosion experiments, microscopic characterization of corrosion product films, and theoretical modeling of droplet spreading and pit development. The findings reveal that flow conditions transform the dominant corrosion mode in the phase transition environment from pitting corrosion in static conditions to uniform corrosion in dynamic conditions. This shift primarily arises from variations in flow rate and CO<sub>2</sub> density, which alter droplet size distribution on the steel surface. Most droplets become smaller than the critical radius required for downward pit propagation, leading to lateral pit expansion rather than deepening. Consequently, uniform corrosion is intensified, while pitting corrosion is mitigated. Furthermore, changes in wall shear stress and droplet dynamics during phase transitions disrupt the structural integrity of corrosion products, further exacerbating uniform corrosion.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106825"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145383119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minxing Zhang , Lidia Montero , Jose A. Mendiola , Elena Ibáñez
{"title":"Towards sustainable extraction of bioactive compounds from guayusa (Ilex guayusa): A comparative study on compressed fluids’ performance","authors":"Minxing Zhang , Lidia Montero , Jose A. Mendiola , Elena Ibáñez","doi":"10.1016/j.supflu.2025.106801","DOIUrl":"10.1016/j.supflu.2025.106801","url":null,"abstract":"<div><div><em>Ilex guayusa</em>, a traditional Amazonian plant rich in caffeine and polyphenols, has attracted interest for its antioxidant and neuroprotective properties. This study evaluates the potential of green compressed fluid extraction techniques to recover bioactive compounds from <em>I. guayusa</em> leaves using environmentally friendly solvents: pressurized liquid extraction (PLE), gas-expanded liquids (GXL), and supercritical fluid extraction (SFE). A mixture design approach combining CO2, ethanol, water, and 2-methyltetrahydrofuran (2-MTHF) in different proportions as solvents was applied to optimize extraction conditions. Among the tested methods, GXL extraction yielded the highest phenolic content and demonstrated superior antioxidant (ABTS and DPPH) and anti-inflammatory (inhibition of lipoxigenase, LOX) activities. Conventional water maceration showed stronger cholinesterase inhibition, suggesting complementary neuroprotective potential. Chemical profiling (HPLC-DAD-ESI-MS/MS) of the optimized extract confirmed the presence of phenolic acids and flavonoids associated with the observed bioactivities. These findings highlight the effectiveness of compressed fluid-based green extraction for obtaining multifunctional phytochemicals from <em>I. guayusa</em>, with promising applications in functional foods and nutraceuticals.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106801"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145271493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fluidization characteristics of supercritical fluidized beds: A comprehensive review","authors":"Yanna Li , Liangzhao Sun , Gongpeng Wu , Yan He","doi":"10.1016/j.supflu.2025.106799","DOIUrl":"10.1016/j.supflu.2025.106799","url":null,"abstract":"<div><div>Fluidized beds (FBs) are widely used in many industrial applications, and continuous improvement of their performance is imperative. However, the inherent limitations of gas-solid FBs, particularly concerning fluidization characteristics, mass transfer efficiency, and operational stability, cannot be adequately addressed solely through structural optimization. Accordingly, fluidized bed reactors using supercritical fluids (SCFs) as fluidizing agents have attracted considerable attention in recent years due to their unique physicochemical properties. Supercritical fluidized beds offer higher fluidization uniformity, reduced bubble diameter, improved particle mixing, and greater bed expansion compared to conventional gas-solid FBs. This review comprehensively examines the advancements in supercritical fluidization technology, with emphasis on supercritical water and carbon dioxide. The main findings indicate that operational parameters, including temperature, pressure, and superficial fluid velocity, exert a substantial influence on fluidization characteristics by modulating the properties of the SCF. Particle properties, including diameter, shape, and size distribution, significantly affect minimum fluidization velocity, bubble dynamics, and bed homogeneity. Predictive correlations for critical parameters are discussed, highlighting their role in reactor design and optimization. Despite notable progress, challenges persist, such as limited experimental data and the limited applicability of traditional fluidized bed testing methodologies to the supercritical domain. This review is of considerable significance for the optimized design of supercritical fluidized beds and provides direction for future applications of supercritical fluidized beds across a wider range of fields.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"229 ","pages":"Article 106799"},"PeriodicalIF":4.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145271492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}