Journal of Supercritical Fluids最新文献_第4页

Phase boundaries and copolymerization of acrylic acid + butyl methacrylate in supercritical carbon dioxide under high-pressure single-fluid initiation 高压单流体引发的超临界二氧化碳中丙烯酸+甲基丙烯酸丁酯的相界和共聚作用

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-17 DOI: 10.1016/j.supflu.2024.106412

Ramses S. Meleán Brito , Joana E. Tasque , Juan M. Padró , Gerardo Martínez Delfa , Miriam C. Strumia , Facundo Mattea , Juan M. Giussi , Juan M. Milanesio

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Micronization of ciprofloxacin by the Supercritical Antisolvent (SAS) Technique 利用超临界反溶剂（SAS）技术微粉化环丙沙星

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-17 DOI: 10.1016/j.supflu.2024.106413

Fouad Zahran , Pablo Marzal , Helga K. Ruiz , Eduardo Pérez , Lourdes Calvo , Albertina Cabañas

{"title":"Micronization of ciprofloxacin by the Supercritical Antisolvent (SAS) Technique","authors":"Fouad Zahran , Pablo Marzal , Helga K. Ruiz , Eduardo Pérez , Lourdes Calvo , Albertina Cabañas","doi":"10.1016/j.supflu.2024.106413","DOIUrl":"10.1016/j.supflu.2024.106413","url":null,"abstract":"<div><div>Ciprofloxacin is a broad-spectrum antibiotic that is proposed for pulmonary administration. In this work micronization of ciprofloxacin was performed by the Supercritical Antisolvent Technique (SAS) using ciprofloxacin base (CIP) in ethanol/acetic acid and ciprofloxacin hydrochloride salt (CIP·HCl) in methanol at 40–60 ºC and 100–150 bar. Yields ranged from 40 % to 90 %. CIP precipitated incorporating acetate whilst CIP·HCl precipitated as the AH1 anhydrous form. CIP and CIP·HCl particles exhibited an acicular morphology (0.2–0.9 μm wide × 1–4 μm long). Micronization adding lactose, PVP K-10 and K-30 modified the precipitate morphology. CIP·HCl:lactose and CIP·HCl:PVP K-30 at a 4:1 drug:excipient mass ratio precipitated like flakes. CIP·HCl:PVP K-10 precipitated as submicron globular particles suitable for oral formulation. Increasing the PVP content, the morphology changed to sheets and flakes, which could be used for pulmonary administration. The antibacterial activity of the samples for <em>Staphylococcus epidermidis</em> was confirmed.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"215 ","pages":"Article 106413"},"PeriodicalIF":3.4,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0896844624002481/pdfft?md5=13d486dd42dd5050356e46807bcdecd3&pid=1-s2.0-S0896844624002481-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142310480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Lipase-catalyzed synthesis of poly(ω-pentadecalactone-co-globalide) in supercritical carbon dioxide 在超临界二氧化碳中脂肪酶催化合成聚(ω-十五内酯-共全球苷)

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-16 DOI: 10.1016/j.supflu.2024.106409

Roseny D. Santos , Evertan A. Rebelatto , Camila Guindani , Heloísa B. Madalosso , Leandro Scorsin , Diego A. Mayer , J. Vladimir Oliveira

{"title":"Lipase-catalyzed synthesis of poly(ω-pentadecalactone-co-globalide) in supercritical carbon dioxide","authors":"Roseny D. Santos , Evertan A. Rebelatto , Camila Guindani , Heloísa B. Madalosso , Leandro Scorsin , Diego A. Mayer , J. Vladimir Oliveira","doi":"10.1016/j.supflu.2024.106409","DOIUrl":"10.1016/j.supflu.2024.106409","url":null,"abstract":"<div><div>This work investigates the enzymatic ring-opening polymerization of poly(ω-pentadecalactone-co-globalide) using supercritical carbon dioxide as a solvent. Copolymerizations were carried out in a high-pressure variable-volume view cell to evaluate the influence of CO<sub>2</sub>:monomers mass ratios and the use of chloroform as a cosolvent. Also, Novozym® 435 and Lipura® Flex were compared as catalysts. The highest molar mass obtained with the use of a cosolvent (M<sub>n</sub> = 24,380 g mol<sup>−1</sup>) was achieved in the 1:2:1 (CO<sub>2</sub>:monomers:chloroform) condition, reflecting the combined effect of the cosolvent and a higher concentration of the monomers, while reactions without it showed better results for molar mass (M<sub>n</sub> up to 27,902 g mol<sup>−1</sup>). Dispersity was higher when a cosolvent was used (Dispersity up to 7.51) than reactions with supercritical carbon dioxide only (Dispersity up to 5.36). Monomer conversions above 97 % and reaction yields from 55.77 wt% up to 79.61 wt% were achieved for copolymerizations with and without a cosolvent, using Novozym® 435 as catalyst. Lipura® Flex produced copolymers with high molar mass (M<sub>n</sub> up to 21,605 g mol<sup>−1</sup>), reaction yields up to 73 wt%, and monomer conversions from 82 % to 96 %.</div></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"215 ","pages":"Article 106409"},"PeriodicalIF":3.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0896844624002444/pdfft?md5=a7e9759219941e1e1796c17e325bf48d&pid=1-s2.0-S0896844624002444-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142310913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Multivariate gradient structure design of flexible thermoplastic polyurethane based composite foam for enhanced electromagnetic interference shielding performance 基于热塑性聚氨酯的柔性复合泡沫的多变量梯度结构设计，提高电磁干扰屏蔽性能

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-16 DOI: 10.1016/j.supflu.2024.106410

Panfeng Shao, Xiaohan Wang, Yishen Zhao, Fangfang Zou, Guangxian Li, Xia Liao

{"title":"Multivariate gradient structure design of flexible thermoplastic polyurethane based composite foam for enhanced electromagnetic interference shielding performance","authors":"Panfeng Shao, Xiaohan Wang, Yishen Zhao, Fangfang Zou, Guangxian Li, Xia Liao","doi":"10.1016/j.supflu.2024.106410","DOIUrl":"10.1016/j.supflu.2024.106410","url":null,"abstract":"<div><p>Flexible and efficient electromagnetic interference (EMI) shielding polymer composite foams are rapidly developing, but it is difficult to avoid the deterioration of shielding properties after foaming. To solve the issue, in this work, composite foams with multivariate gradient structure of thermoplastic polyurethane (TPU) mixed with multiwalled carbon nanotubes (MWCNTs) were constructed by combining the soft-hard domains proportional gradient of TPU with filler content gradient. Gradient-structured TPU/MWCNTs foams with impedance matching layer and high reflector layer were obtained and impedance matching layer with large cells significantly reduced the density while high reflector layer with a few cells maintained relatively perfect conductive network, whose shielding efficiency was 38.2 % higher than that of unfoamed sample. Furthermore, TPU/MWCNTs composite foams presented great stability even after 1000 times bending. This special multivariate gradient structure shows potential applications in microelectronic devices and aerospace fields and is critical to the development of high-performance EMI shielding polymer foams.</p></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"215 ","pages":"Article 106410"},"PeriodicalIF":3.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0896844624002456/pdfft?md5=818b9351d08c460e2a02cfcba5bce4db&pid=1-s2.0-S0896844624002456-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142239909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Supercritical fluid extraction of coumarins and flavonoids from citrus peel 从柑橘皮中超临界流体萃取香豆素和黄酮类化合物

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-05 DOI: 10.1016/j.supflu.2024.106396

Juan J. Mora , Henrique M. Tavares , Romina Curbelo , Eduardo Dellacassa , Eduardo Cassel , Miriam A. Apel , Gilsane L. von Poser , Rubem M.F. Vargas

{"title":"Supercritical fluid extraction of coumarins and flavonoids from citrus peel","authors":"Juan J. Mora , Henrique M. Tavares , Romina Curbelo , Eduardo Dellacassa , Eduardo Cassel , Miriam A. Apel , Gilsane L. von Poser , Rubem M.F. Vargas","doi":"10.1016/j.supflu.2024.106396","DOIUrl":"10.1016/j.supflu.2024.106396","url":null,"abstract":"<div><p>The production manufacture of juices generates a large amount of waste consisting mainly of fruit peels. The peels are source of molecules such as coumarins and flavonoids. In this study, the peels of <em>Citrus limonia</em>, <em>Citrus deliciosa</em>, <em>Citrus latifolia</em> and <em>Citrus sinensis</em> were the raw material for supercritical fluid extraction. The Box-Behnken design was used to optimize the global yield in function of process variables. The chemical analysis of the extract was carried out by LC-MS and GC-MS. CFD was applied to the mass and momentum conservation equations in the study of supercritical extraction using citrus peels, which allowed the determination of unknown parameters of the bidimensional mathematical model. The flavonoids, nobiletin, sinensetin and tangeretin, as well as the coumarin, citropten, were identified in all species investigated. The maximum global yield obtained were 3.93 % for <em>Citrus limonia</em>, 4.18 % for <em>Citrus deliciosa</em>, 3.48 % for <em>Citrus latifolia</em> and 5.32 % for <em>Citrus sinensis</em>.</p></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"215 ","pages":"Article 106396"},"PeriodicalIF":3.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0896844624002316/pdfft?md5=3e32724276d589a6119ca90e6728741a&pid=1-s2.0-S0896844624002316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142167829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Fabrication of electromagnetic wave absorption nanocomposite foam with adjustable conductive network by supercritical carbon dioxide foaming 利用超临界二氧化碳发泡技术制造具有可调导电网络的电磁波吸收纳米复合泡沫

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-09-05 DOI: 10.1016/j.supflu.2024.106395

Yishen Zhao , Kun Li , Yanru Li , Xiaoli Zhang , Shixun Zhang , Xia Liao , Jingbo Chen , Chul B. Park

{"title":"Fabrication of electromagnetic wave absorption nanocomposite foam with adjustable conductive network by supercritical carbon dioxide foaming","authors":"Yishen Zhao , Kun Li , Yanru Li , Xiaoli Zhang , Shixun Zhang , Xia Liao , Jingbo Chen , Chul B. Park","doi":"10.1016/j.supflu.2024.106395","DOIUrl":"10.1016/j.supflu.2024.106395","url":null,"abstract":"<div><p>Polymer nanocomposite foams with high electromagnetic interference (EMI) shielding performance have become the research hotspot to reduce electromagnetic wave pollution. Herein, we prepared polyethylene/poly (vinylidene fluoride)/carbon nanotubes/Fe<sub>3</sub>O<sub>4</sub>(PE/PVDF/Fe<sub>3</sub>O<sub>4</sub>/CNTs) nanocomposites and nanocomposite foams by following the simple melt blending and batch foaming procedures. The co-continuous structure system of PVDF/PE was achieved by altering the matrix ratio of PVDF/PE, while reaching a maximum average EMI shielding efficiency of ca. 28 dB for the nanocomposite with PVDF/PE ratio of 5:5. Furthermore, the largest specific EMI SE of as high as 275 dB‧cm<sup>2</sup>‧g<sup>−1</sup> was obtained for the nanocomposite foam with PVDF/PE ratio of 9: 1, in which the EMI shielding mechanism is mainly based on absorption, leading to a significantly reduction in the secondary EM wave pollution. Therefore, the preparation of porous polymer nanocomposite foams with excellent EM wave absorption performance served as a novel strategy to reduce secondary EM wave pollution that holds great potential for applications in both military and civilian fields.</p></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"215 ","pages":"Article 106395"},"PeriodicalIF":3.4,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0896844624002304/pdfft?md5=489bf1582d5d55b5498823c3484be72b&pid=1-s2.0-S0896844624002304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Comparative analysis of biological potential of acerola by-product extracts obtained by hydrothermal and gas-expanded liquid extraction 通过水热萃取和气体膨胀液体萃取获得的针叶树副产品提取物的生物潜力比较分析

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-08-31 DOI: 10.1016/j.supflu.2024.106394

Otília Mônica Alves Borges , Karina Cesca , Laís Benvenutti , Matheus Henrique Oliveira de Sousa , Neusa Fernandes de Moura , Jose David Sánchez-Martinez , Alejandro Cifuentes , Acácio A.F. Zielinski , Patrícia Poletto

{"title":"Comparative analysis of biological potential of acerola by-product extracts obtained by hydrothermal and gas-expanded liquid extraction","authors":"Otília Mônica Alves Borges , Karina Cesca , Laís Benvenutti , Matheus Henrique Oliveira de Sousa , Neusa Fernandes de Moura , Jose David Sánchez-Martinez , Alejandro Cifuentes , Acácio A.F. Zielinski , Patrícia Poletto","doi":"10.1016/j.supflu.2024.106394","DOIUrl":"10.1016/j.supflu.2024.106394","url":null,"abstract":"<div><p>The acerola non-pomace, a by-product from the juice clarification step and rich in phenolic compounds and ascorbic acid, was investigated for its biological potential through <em>in vitro</em> tests. Extracts were obtained using hydrothermal extraction (HT) at 121°C as well as CO<sub>2</sub>-expanded ethanol (GXL) at 40°C. The GXL extract contained 159 mg/g of ascorbic acid, while the HT extract showed 70 mg/g. Catechin was found only in the HT extract, and quercetin only in the GXL extract. Both extracts exhibited similar antiglycemic potential, but the GXL extract showed twice the neuroprotective potential against acetylcholinesterase (AChE, IC<sub>50</sub>=302 μg/mL) and lipoxygenase (LOX, IC<sub>50</sub>=227 μg/mL) activities. In human breast cancer cells (MDA-MB-231), the GXL extract demonstrated better antitumor potential with an IC<sub>50</sub> of 100 μg/mL compared to 250 μg/mL for the HT extract.</p></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"214 ","pages":"Article 106394"},"PeriodicalIF":3.4,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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An experimental and modeling study of propane oxidation kinetics in low temperature supercritical water 低温超临界水中丙烷氧化动力学的实验和模型研究

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-08-26 DOI: 10.1016/j.supflu.2024.106392

A. Mansfield , N. Sophonrat

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Chemometric assisted green extraction of tyrosinase inhibitor from Durio zibethinus rind for skin whitening agents in cosmetic products 化学计量学辅助绿色提取 Durio zibethinus 外皮中的酪氨酸酶抑制剂，用于化妆品中的皮肤美白剂

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-08-26 DOI: 10.1016/j.supflu.2024.106393

Sofiyyah Ismail , Erna Normaya , Syamimi Sulfiza Shamsuri , Anwar Iqbal , Mohd Bijarimi Mat Piah , Sharifuddin Md Zain , Mohammad Norazmi Ahmad

{"title":"Chemometric assisted green extraction of tyrosinase inhibitor from Durio zibethinus rind for skin whitening agents in cosmetic products","authors":"Sofiyyah Ismail , Erna Normaya , Syamimi Sulfiza Shamsuri , Anwar Iqbal , Mohd Bijarimi Mat Piah , Sharifuddin Md Zain , Mohammad Norazmi Ahmad","doi":"10.1016/j.supflu.2024.106393","DOIUrl":"10.1016/j.supflu.2024.106393","url":null,"abstract":"<div><p>Cosmetics typically contain artificial substances that could be harmful to people's health. Extended usage and exposure to these harmful substances are frequently linked to a number of negative impacts and illnesses. This study processed a <em>Durio zibethinus</em> rind, rich in natural antityrosinase properties, with a chemometric-assisted green extraction system. The TPC value was obtained at the optimum conditions (34.4 MPa, 62°C, and 86 min). GC-MS and FTIR spectroscopy were performed to identify the phenolic compounds and their functional group, respectively. The optimized extract contains 77 % of the mushroom tyrosinase activity. PCA shows that aspidospermidin-17-ol,1-acetyl-19,21-apoxy-15,16-dimethoxy- (AP) resembles the similar cluster with hydroquinone. COSMO-RS was used to investigate the extraction mechanism of CO<sub>2</sub> and AP during the SFE process. DFT and molecular docking were used to calculate the chemical reactivity and explain the tyrosinase inhibition mechanism, respectively. ADME-Tox and OSIRIS Property Explorer showed no violation of Lipinski’s rule, and toxicity with AP. In conclusion, a high-value, natural and safe cosmetic ingredient (AP) for cosmetopea was discovered using an innovative green extraction system.</p></div>","PeriodicalId":17078,"journal":{"name":"Journal of Supercritical Fluids","volume":"214 ","pages":"Article 106393"},"PeriodicalIF":3.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Supercritical fluid impregnation of phenolic compounds from passion fruit bagasse in corn starch aerogels: Phase behavior and effect of operation mode 玉米淀粉气凝胶中百香果蔗渣酚类化合物的超临界流体浸渍：相行为和操作模式的影响

IF 3.4 3区工程技术

Journal of Supercritical Fluids Pub Date : 2024-08-24 DOI: 10.1016/j.supflu.2024.106387

Erick Jarles Santos de Araujo , Arthur Jessé Oliveira Braga , José Claudio Klier Monteiro Filho , Papa Matar Ndiaye , Rodney Alexandre Ferreira Rodrigues , Julian Martínez

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