Journal of Research in Clinical Medicine最新文献_第5页

A case report of Fahr’s disease presenting with cerebellar ataxia 以小脑共济失调为表现的Fahr病1例报告

Journal of Research in Clinical Medicine Pub Date : 2023-02-27 DOI: 10.34172/jrcm.2023.32087

M. Yazdchi, Ramin Khanalizadeh, N. Forghani, Z. Jalali, M. Talebi

引用次数: 0

A review on statins with a focus on type 2 diabetes 他汀类药物治疗2型糖尿病的综述

Journal of Research in Clinical Medicine Pub Date : 2023-02-26 DOI: 10.34172/jrcm.2023.32150

Vahieh Sadra, Mitar Niafar, V. Hosseini, A. Mehdizadeh

引用次数: 0

Comparison of liver elastography results in COVID-19 patients with and without increased liver enzymes 肝酶升高与不升高的COVID-19患者肝弹性成像结果的比较

Journal of Research in Clinical Medicine Pub Date : 2023-02-22 DOI: 10.34172/jrcm.2023.32226

Masood Faghieh Dinevari, S. Abbasian, Masoud Hejazi, A. Riazi

{"title":"Comparison of liver elastography results in COVID-19 patients with and without increased liver enzymes","authors":"Masood Faghieh Dinevari, S. Abbasian, Masoud Hejazi, A. Riazi","doi":"10.34172/jrcm.2023.32226","DOIUrl":"https://doi.org/10.34172/jrcm.2023.32226","url":null,"abstract":"Introduction: The coronavirus disease 20149 (COVID-19) may be associated with the elevated liver enzymes including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), in which the disease has been associated with more severity. Liver stiffness (LS) is associated with the increased liver enzymes. Liver elastography is a non-invasive technique that is used to evaluate LS. This study aimed to evaluate the functional status of liver and its relationship with liver elastography results in the patients with COVID-19. Methods: In this cross-sectional study, 90 patients with COVID-19, whose diagnosis was confirmed by polymerase chain reaction (PCR) test, were included. Levels of liver enzymes were measured and the patients underwent liver elastography. Liver size and interquartile range-median (IQR/M) of LS were also measured. Six months later, the patients underwent another liver elastography and measurement of liver enzymes. Results: The frequency of fatty liver in the case group was significantly higher compared to the control group but no significant difference was observed in the frequency of liver fibrosis between two groups. In patients with COVID-19, the LS and IQR/M values at the beginning and six months after recovery were significantly higher in the group with the increased liver enzymes (case) compared to the group without the increased enzymes (control). P value was 0.001. Conclusion: The use of elastography to evaluate LS in the patients with COVID-19 can be significantly effective in assessing the status of liver damage and inflammation of liver tissue. Since elastography is an inexpensive and non-invasive available tool, it can be used mainly in most medical centers.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86344714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A survey on the knowledge of patients’ companions about the concept and application of hospital triage 患者陪伴者对医院分诊概念及应用知识的调查

Journal of Research in Clinical Medicine Pub Date : 2022-12-27 DOI: 10.34172/jrcm.2022.032

M. Yasinzadeh, Hila Shahriari, M. Rezai, M. Eslami, Mehdi Banijamal, H. Amiri

{"title":"A survey on the knowledge of patients’ companions about the concept and application of hospital triage","authors":"M. Yasinzadeh, Hila Shahriari, M. Rezai, M. Eslami, Mehdi Banijamal, H. Amiri","doi":"10.34172/jrcm.2022.032","DOIUrl":"https://doi.org/10.34172/jrcm.2022.032","url":null,"abstract":"Introduction: Given the importance of the subject and the knowledge gap, we decided to perform this survey. Methods: In this descriptive cross-sectional study, the knowledge levels of patients’ companions about the concept and application of hospital triage were evaluated in 202 subjects. The research population included patient companions referred to the emergency department (ED). The exclusion criterion was the failure to complete the questionnaire. Convenience sampling was done. Questionnaires were delivered to the companions of the patients. In this study, the data gathering tool was a questionnaire consisting of two parts. The final questionnaire included 13 questions, 10 and 3 of which were closed (multiple choice) and open questions, respectively. Finally, the age, level of education, and gender were also asked from participants. The level of patient triage was also determined in this research. Results: 202 questionnaires were completed by companions of patients admitted to the ED. The mean age of those who completed the questionnaire was 39.95±17.92 years, and 192 individuals expressed their gender, of which 123 (64.1%) and 69 (35.9%) persons were male and female, respectively. The level of education was also reported in 180 people. Moreover, diploma and postgraduate diplomas, bachelor’s degrees, and postgraduate or doctoral degrees were observed in 59 (32.77%), 90 (50%), and 31 (17.22%) patients’ companions respectively. Conclusion: According to the results, it seems that the knowledge about the concept of triage among ordinary people of the society is lower than the desired level.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86201964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Posterior reversible encephalopathic syndrome in systemic lupus erythematous: A case report 系统性红斑狼疮后可逆性脑病综合征1例报告

Journal of Research in Clinical Medicine Pub Date : 2022-12-26 DOI: 10.34172/jrcm.2022.031

S. Hosseini

引用次数: 0

Shape memory polymers in osteochondral tissue engineering 形状记忆聚合物在骨软骨组织工程中的应用

Journal of Research in Clinical Medicine Pub Date : 2022-12-25 DOI: 10.34172/jrcm.2022.030

S. Saghati, R. Rahbarghazi, Sonia Fathi Karkan, Sajed Nazifkerdar, A. Khoshfetrat, Hamid Tayefi Nasrabadi

引用次数: 0

The prognostic values of platelet to lymphocyte ratio for predicting mortality in patients with acute mesenteric ischemia: a cross-sectional study 血小板与淋巴细胞比值预测急性肠系膜缺血患者死亡率的预后价值:一项横断面研究

Journal of Research in Clinical Medicine Pub Date : 2022-12-24 DOI: 10.34172/jrcm.2022.029

A. Ala, Jafar Ghobadi, Haleh Yaghubi, A. Adib

{"title":"The prognostic values of platelet to lymphocyte ratio for predicting mortality in patients with acute mesenteric ischemia: a cross-sectional study","authors":"A. Ala, Jafar Ghobadi, Haleh Yaghubi, A. Adib","doi":"10.34172/jrcm.2022.029","DOIUrl":"https://doi.org/10.34172/jrcm.2022.029","url":null,"abstract":"Introduction: Acute mesenteric ischemia (AMI) is a life-threatening disease that can cause multi-organ damage and ultimately lead to death. Early diagnosis and treatment significantly reduce morbidity and mortality rates in high-risk patients. This study aimed to explore the prognostic values of platelet to lymphocyte ratio (PLR) in predicting mortality in patients with mesenteric ischemia. Methods: This prospective study included 126 patients with a complaint of acute abdominal pain, suggesting mesenteric ischemia. Demographic data and measured variables were determined using a pre-designed questionnaire. Statistical analysis was conducted using t test analysis, Spearman correlation analysis, and receiver operating characteristic (ROC) curve. Results: Of 126 studied cases, mesenteric ischemia was confirmed in 47 patients. The mean age in patients with mesenteric ischemia (68 years) was significantly higher than that of non-ischemic patients (65 years). Mean blood bicarbonate level in non-ischemic patients (13.53 mmol/L) was higher than ischemic patients (11.15 mmol/L) (P<0.0001). PLR in patients with mesenteric ischemia and non-ischemic patients was 159 and 151, respectively; this difference was not statistically significant (P=0.14). The overall mortality rate in this study was 61%. Conclusion: Even though the PLR increases in patients with systemic inflammation, it cannot distinguish between patients with mesenteric ischemia and other inflammatory conditions.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84690074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seronegative spondyloarthropathy (reactive arthritis) fourteen days following E. coli UTI: Case report 大肠杆菌尿路感染后14天血清阴性的脊椎关节病(反应性关节炎):病例报告

Journal of Research in Clinical Medicine Pub Date : 2022-12-24 DOI: 10.34172/jrcm.2022.028

Inderbir Padda, Rajat Bhatt, Glady Mathew, Gurnaaz Malhi, Manpreet Hans

引用次数: 0

A novel method for early detection of MIC value – Broth dilution using indicator solution versus agar dilution: an original article 早期检测MIC值的新方法——指示剂溶液与琼脂稀释的肉汤稀释:一篇原创文章

Journal of Research in Clinical Medicine Pub Date : 2022-12-17 DOI: 10.34172/jrcm.2022.027

Rohon Das Roy, Subhayan Das Gupta

{"title":"A novel method for early detection of MIC value – Broth dilution using indicator solution versus agar dilution: an original article","authors":"Rohon Das Roy, Subhayan Das Gupta","doi":"10.34172/jrcm.2022.027","DOIUrl":"https://doi.org/10.34172/jrcm.2022.027","url":null,"abstract":"Introduction: The adequate protocol for treatment of an infection is often determined on the basis of the minimum inhibitory concentration (MIC) of the causative organism. Traditional methods (agar dilution, microbroth dilution, and gradient diffusion) are labour intensive and time consuming (they are usually take over 48 hours to report the results). On the other hand, automated systems (VITEK™, Phoenix™, MicroScan WalkAway™) and rapid methods of MIC detection (using dielectrophoresis (DEP), magnetic bead rotation sensors and microfluidic incubation) require expensive instruments. This study is aimed to develop a rapid MIC detection method with the ability to applied to a resource limited setting. Methods: Agar dilution method and a novel broth dilution method (containing indicator solution) were simultaneously performed using amikacin, ceftriaxone, piperacillin-tazobactam, imipenem, cefoxitin and azithromycin. Results: Isolates of Escherichia coli, Enterobacter spp, Klebsiella spp, Staphylococcus aureus, Proteus mirabilis, Acinetobacter spp and Pseudomonas spp were used. The MIC values for Enterobacteriaceae and S. aureus isolates for each antibiotic were obtained within 4 to 5 hours by a novel broth dilution method. The obtained MIC values were corresponded with the MIC shown on the following day by agar dilution method. Conclusion: Broth dilution method with indicator solution is effective in rapid determination of the MIC for cephalosporins, penicillin, carbapenems, cephamycin, aminoglycosides and macrolides for most isolates of Enterobacteriaceae and S. aureus. Unfortunately this method did not work for the non-fermenter group of organisms like Pseudomonas spp and Acinetobacter spp, as their results could not be obtained before 24 hours. The method is time saving, relatively inexpensive and is applicable to resource limited settings.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78687777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of calcium and phosphorus homeostasis between hemodialysis and peritoneal dialysis in patients with end-stage renal disease 终末期肾病患者血液透析与腹膜透析钙磷稳态的比较

Journal of Research in Clinical Medicine Pub Date : 2022-12-10 DOI: 10.34172/jrcm.2022.026

Vahieh Sadra, Mehran Rahimi, F. Najafipour, R. Habibi

{"title":"Comparison of calcium and phosphorus homeostasis between hemodialysis and peritoneal dialysis in patients with end-stage renal disease","authors":"Vahieh Sadra, Mehran Rahimi, F. Najafipour, R. Habibi","doi":"10.34172/jrcm.2022.026","DOIUrl":"https://doi.org/10.34172/jrcm.2022.026","url":null,"abstract":"Introduction: Chronic kidney disease (CKD) and subsequent end-stage renal disease (ESRD) are public health problems worldwide, and their prevalence is increasing worldwide. Abnormalities in calcium and phosphorus are common problems that need to be considered alongside other important factors when choosing a dialysis method. Hence, the present study aimed to assess and compare the calcium and phosphorus homeostasis in ESRD patients on hemodialysis and peritoneal dialysis (PD). Methods: In this descriptive cross-sectional study, 150 patients with ESRD on hemodialysis and 150 patients with ESRD on PD in the dialysis department of Imam Reza hospital of Tabriz University were selected randomly. The serum levels of calcium, phosphorus, and intact parathyroid hormone (iPTH) before the initiation of dialysis and one year afterward were considered for comparison. Results: In the hemodialysis group, 33.1% of patients were female and 66.9% were male but in the PD group, sex distribution was 47% males and 53% females. Following one year of dialysis, mean calcium (Ca), phosphorus (P), and iPTH levels were significantly higher in the hemodialysis group compared to PD patients (P<0.05). Also, the mean Ca×P product was significantly higher in patients undergoing PD (P=0.05). Conclusion: Our findings suggested that calcium, phosphorus and iPTH levels increase with prolonged hemodialysis rather than PD, and the rate of Ca×P in patients is significantly higher in PD patients after one year.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86569872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0