{"title":"Quiz questions from skin and systemic diseases","authors":"S. Jagadeesan, Prateek Nayak","doi":"10.25259/jsstd_20_2022","DOIUrl":"https://doi.org/10.25259/jsstd_20_2022","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"355 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82616701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quiz questions from tumors of skin and appendages","authors":"Parambath Nimitha","doi":"10.25259/jsstd_10_2022","DOIUrl":"https://doi.org/10.25259/jsstd_10_2022","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90634296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Caspase recruitment domain-containing proteins and dermatoses","authors":"Fibin Thanveer, L. Ali","doi":"10.25259/jsstd_8_2022","DOIUrl":"https://doi.org/10.25259/jsstd_8_2022","url":null,"abstract":"The caspase recruitment domain (CARD) is a protein interaction module that comes under the death domain superfamily. CARD mediates important cellular signaling events. Abnormalities in these cellular signaling events play a role in the pathogenesis of malignancies and immune disorders. The significance of CARD in dermatological diseases is less discussed. Mutations affecting CARD-containing proteins are reported to play a pathogenic role in certain patients with dermatoses such as psoriasis, pityriasis rubra pilaris, atopic dermatitis, and fungal infections. These underlying mutations are suggested to have therapeutic implications in various dermatoses, though more information is needed regarding this. This review discusses the association between dermatoses and mutations involving CARD-containing proteins.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81462600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Femina Azeez, K. Sobhanakumari, M. Zacharia, Seena Palakkal, Kiran Shaj
{"title":"Becker’s nevus and lichen planus: A rare coexistence","authors":"Femina Azeez, K. Sobhanakumari, M. Zacharia, Seena Palakkal, Kiran Shaj","doi":"10.25259/jsstd_11_2022","DOIUrl":"https://doi.org/10.25259/jsstd_11_2022","url":null,"abstract":"Becker’s nevus, an epidermal nevus, may occur alone or may be associated with musculoskeletal anomalies. There are reports of certain inflammatory and neoplastic diseases showing a predilection for Becker’s nevus. We report a patient who manifested lesions of lichen planus. Interestingly, the lesions showed a predilection for a cutaneous area that harbored a Becker’s nevus. We reviewed similar cases where a Becker’s nevus was reported as a site of predilection for other dermatoses and suggest that the possibility of the former acting as an immunocompromised district of Ruocco (an area that shows less resistance to a disease process in comparison to other body areas) may be considered.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85136554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikhila K. Narayanan, M. Vineetha, Seena Palakkal, P. L. Jayalakshmy, Lissy Skaria, C. M. Issac, T. K. Jaseela
{"title":"Minocycline-induced acute generalized exanthematous pustulosis in a patient with lepromatous leprosy","authors":"Nikhila K. Narayanan, M. Vineetha, Seena Palakkal, P. L. Jayalakshmy, Lissy Skaria, C. M. Issac, T. K. Jaseela","doi":"10.25259/jsstd_76_2021","DOIUrl":"https://doi.org/10.25259/jsstd_76_2021","url":null,"abstract":"Cutaneous manifestations of leprosy are variable. It is a known fact that, in addition to the skin lesions related to the disease, multidrug therapy can also have an impact on patient’s skin. In this report, we discuss a young girl with leprosy, who developed acute generalized exanthematous pustulosis to minocycline, which was given as an anti-leprosy drug.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87637925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Jose, M. Zacharia, P. L. Jayalakshmy, K. Sobhanakumari
{"title":"Alagille syndrome: A rare cause for xanthomatosis","authors":"N. Jose, M. Zacharia, P. L. Jayalakshmy, K. Sobhanakumari","doi":"10.25259/jsstd_1_2022","DOIUrl":"https://doi.org/10.25259/jsstd_1_2022","url":null,"abstract":"Alagille syndrome (ALGS) is a rare, autosomal dominant disorder characterized by typical facial features, cholestatic jaundice, and renal, cardiac, eye, and vertebral anomalies. Cholestasis can lead to multiple xanthomas in childhood. We report this case to emphasize the cutaneous features and the lipid abnormalities associated with ALGS. We highlight the importance of a detailed evaluation in patients with multiple xanthomas, especially children, as it may reveal an underlying serious systemic involvement.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83786220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vulvar inflammatory disorders: A review","authors":"S. Prabhu, Swathy Krishna","doi":"10.25259/jsstd_11_2021","DOIUrl":"https://doi.org/10.25259/jsstd_11_2021","url":null,"abstract":"Vulvar inflammatory disorders (VID) are a miscellaneous group of non-infectious conditions of the vulvar area, which can be broadly classified based on etiology and pathology. Here, we discuss a few pertinent VID including vulvar dermatitis, psoriasis, lichen planus, and lichen sclerosus. This review will focus only on common VID, and a few rare conditions with characteristic features such as Crohn’s disease, plasma cell vulvitis, acantholytic disorder of genitocrural area, desquamative vulvitis, and atrophic vulvovaginitis. A thorough history taking and relevant investigations including dermoscopy and biopsy are relevant to proper diagnosis and management of VID. Early management of VID is essential since these conditions are prone to interfere with psychosexual functioning of the patient. Potent topical steroids are the first line management in most cases, followed by topical calcineurin inhibitors, emollients, and antihistamines. Vulvar area is resistant to steroid induced atrophy; hence, use of potent topical steroids does not pose a problem. Oral steroids or steroid sparing agents are used in resistant cases.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79775910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vulvar premalignancies – A dermatologist’s perspective","authors":"A. Kavitha, P. Deeksha","doi":"10.25259/jsstd_32_2021","DOIUrl":"https://doi.org/10.25259/jsstd_32_2021","url":null,"abstract":"Vulvar malignancies are rarely encountered in dermatology, yet it is imperative to develop a thorough clinical and diagnostic acumen, as early detection and appropriate treatment can improve quality of life or even prevent fatal outcome. The common premalignant vulvar lesions are vulvar intraepithelial neoplasia (VIN), vulvar Paget’s disease, and melanoma in situ. These are notable since they are associated with a high post-treatment recurrence rate. The incidence of VIN is increasing in younger women. Early diagnosis and tailoring the management on individual basis may help to reduce the long-term morbidity. This review describes etiology, clinical features, management, and prognosis of vulvar premalignancies.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74836654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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