2006 International Conference on Microtechnologies in Medicine and Biology最新文献_第7页

Finite Element Analysis of Planar Micromachined Silicon Electrodes for Cortical Stimulation 平面微加工硅电极皮层刺激的有限元分析

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251533

R. Field, Maysam Ghovanloo

引用次数: 0

Evaluation of Cell Velocity Regulation in a Microfabricated Adhesion-Based Cell Separation Device 微制造黏附细胞分离装置中细胞速度调节的评价

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251501

J. Miwa, Y. Suzuki, N. Kasagi

引用次数: 2

Effects of pH on the Morphological Structures and Release Properties in Chitosan Microspheres pH对壳聚糖微球形态结构及释放特性的影响

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251535

S. Kuo, S. Chang, Pei-Hwa Tsai, S. Chen

{"title":"Effects of pH on the Morphological Structures and Release Properties in Chitosan Microspheres","authors":"S. Kuo, S. Chang, Pei-Hwa Tsai, S. Chen","doi":"10.1109/MMB.2006.251535","DOIUrl":"https://doi.org/10.1109/MMB.2006.251535","url":null,"abstract":"With an attempt to expand the versatilities and applications in chitosan microspheres, distinct morphological structures and properties of chitosan microspheres were produced by treating with various pH values of Na5P3O10/NaOH solution reagents, also under various volume ratio of these solution (17/3, 19/1, pure Na5P3O10 or pure NaOH solution). The prepared chitosan microsphere had a good spherical shape and was in a range of 185.8plusmn13.8 mum to 380.9plusmn11.5 mum in diameter. When pH values decreased from initially pH 12 (except in case for pure Na5P3O10 where the pH being 8.8) to pH 7, the chitosan microspheres size varied, and reached a maximum diameter after treatment with pH 7 of these reaction agents. The prepared chitosan microspheres upon treatment with pH 7 of various ratios Na5P3O10/NaOH solution, all exhibited a shrunken surface morphological structure. This densely shrunken structure of microspheres yielded a stronger mechanical strength and a slower release rate of drug (5-FU), no matter what the ratios of Na5P3O10/NaOH solution was used. From the data of FTIR analyses, the protonated amino peak of NH 3 + at around 1562 cm-1 has decreased significantly. It could be attributed to the crosslinking reaction between phosphoric and ammonium ion of the chitosan microspheres","PeriodicalId":170356,"journal":{"name":"2006 International Conference on Microtechnologies in Medicine and Biology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125334640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adsorption-induced inactivation of heavy meromyosin on polymer surfaces imposes effective drag force on sliding actin filaments in vitro 吸附诱导的重肌球蛋白在聚合物表面的失活对滑动的肌动蛋白丝施加有效的阻力

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251514

K. Hanson, G. Solana, V. Vaidyanathan, D. Nicolau

{"title":"Adsorption-induced inactivation of heavy meromyosin on polymer surfaces imposes effective drag force on sliding actin filaments in vitro","authors":"K. Hanson, G. Solana, V. Vaidyanathan, D. Nicolau","doi":"10.1109/MMB.2006.251514","DOIUrl":"https://doi.org/10.1109/MMB.2006.251514","url":null,"abstract":"Actin and myosin are of interest as potential force-generating elements in engineered nanodevices. Such applications require surface coatings which are both biocompatible and amenable to nanolithographic processing, but the manner in which surfaces modulate motor protein function has not been rigorously studied. Here we examine motor protein surface density and bioactivity on a variety of polymer surfaces, and compare the results to in vitro actomyosin motility characteristics. Filament velocities were found to be controlled by the proportion, rather than density, of active heavy meromyosin (HMM), consistent with the imposition of an effective drag force by inactivated HMM due to weak actin-binding interactions. Interpretation of the results with respect to previous models suggests that the inactive HMM fraction has no force-generating ability, and that the effective drag imposed on polystyrene is lower than that on methacrylate polymers and nitrocellulose, consistent with a higher degree of protein denaturation on aromatic surface structures","PeriodicalId":170356,"journal":{"name":"2006 International Conference on Microtechnologies in Medicine and Biology","volume":"250 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115206491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bubble lodging in bifurcating microvessel networks: a microfluidic model 分岔微血管网络中的气泡倒伏:微流控模型

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251528

A. Calderón, Y. Heo, D. Huh, F. Nobuyuki, S. Takayama, J. Fowlkes, J. Bull

{"title":"Bubble lodging in bifurcating microvessel networks: a microfluidic model","authors":"A. Calderón, Y. Heo, D. Huh, F. Nobuyuki, S. Takayama, J. Fowlkes, J. Bull","doi":"10.1109/MMB.2006.251528","DOIUrl":"https://doi.org/10.1109/MMB.2006.251528","url":null,"abstract":"Lodging of cardiovascular gas bubbles is investigated in a microfluidic model of small arteriole bifurcations. These experiments address the dynamics of the lodging mechanism of gas bubbles in bifurcations. This work is motivated by a novel gas embolotherapy technique for the potential treatment of cancer by tumor infarction. The experimental model arteriole bifurcations were constructed from a transparent elastomer (polydimethylsiloxane). A single air bubble was suspended in water within the parent tube of the bifurcation and a specified driving pressure was imposed via constant elevation reservoirs that were open to atmospheric pressure. The driving pressure and bubble size were varied, and their effects on the bubble lodging were assessed. The results show that the pressure to lodge a bubble in a bifurcation is less than to dislodge it. It was also possible to occlude an entire bifurcation and multiple bifurcation devices with bubbles. Splitting ratios were assessed in the range of lodging to dislodging pressure where we observed an instability in bubble splitting. From the results we estimate that gas bubbles from embolotherapy can lodge in vessels 21 mum or smaller in diameter. These findings may be useful in developing strategies for microbubble delivery in gas embolotherapy","PeriodicalId":170356,"journal":{"name":"2006 International Conference on Microtechnologies in Medicine and Biology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129506977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell-based field effect devices for cell adhesion analysis 用于细胞粘附分析的基于细胞的场效应装置

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251521

T. Sakata, Y. Miyahara

引用次数: 1

Fabrication of Taste Sensor Chip and Portable Taste Sensor System 味觉传感芯片及便携式味觉传感系统的研制

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251522

S. Etoh, M. Iwakura, K. Nakashi, R. Hattori, R. Hayashi, K. Toko

引用次数: 4

Receding meniscus induced docking of yeast cells inside microfluidic channels at single cell level 退半月板诱导酵母细胞在单细胞水平上在微流体通道内对接

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251540

Min Cheol Park, J. Hur, K. Kwon, Jee-Won Park, Sang-Hyun Park, K. Suh

引用次数: 0

A new injectable tissue engineered scaffold for regenerative medicine 一种用于再生医学的新型可注射组织工程支架

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251477

H. Hosseinkhani, M. Hosseinkhani, H. Kobayashi

引用次数: 1

Controlled Bacterial Micro-actuation 可控细菌微驱动

2006 International Conference on Microtechnologies in Medicine and Biology Pub Date : 2006-05-09 DOI: 10.1109/MMB.2006.251498

Sylvain Martel

引用次数: 35